$186 Cheap Flights from Medellín (MDE) to Charlotte (CLT)

View $186 flight on Mon, Nov 17, 2025Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT)

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Cheap Flights from Medellín to Charlotte (MDE-CLT)

Prices were available within the past 7 days and start at $186 for one-way flights and $270 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Thu, Oct 9 - Wed, Nov 12
MDE
Medellin
CLT
Charlotte
$270 Roundtrip, found 4 hours ago
$270
Roundtrip
found 4 hours ago
Select Spirit Airlines flight, departing Thu, Oct 9 from Medellin to Charlotte, returning Wed, Nov 12, priced at $270 found 4 hours ago
Spirit Airlines
Wed, Nov 12 - Sun, Nov 16
MDE
Medellin
CLT
Charlotte
$292 Roundtrip, found 1 day ago
$292
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Wed, Nov 12 from Medellin to Charlotte, returning Sun, Nov 16, priced at $292 found 1 day ago
Spirit Airlines
Wed, Nov 12 - Sun, Nov 16
MDE
Medellin
CLT
Charlotte
$301 Roundtrip, found 1 day ago
$301
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Wed, Nov 12 from Medellin to Charlotte, returning Sun, Nov 16, priced at $301 found 1 day ago
Spirit Airlines
Wed, Nov 5 - Wed, Dec 10
MDE
Medellin
CLT
Charlotte
$306 Roundtrip, found 8 hours ago
$306
Roundtrip
found 8 hours ago
Select Spirit Airlines flight, departing Wed, Nov 5 from Medellin to Charlotte, returning Wed, Dec 10, priced at $306 found 8 hours ago
Spirit Airlines
Thu, Oct 9 - Wed, Nov 12
MDE
Medellin
CLT
Charlotte
$313 Roundtrip, found 4 hours ago
$313
Roundtrip
found 4 hours ago
Select Spirit Airlines flight, departing Thu, Oct 9 from Medellin to Charlotte, returning Wed, Nov 12, priced at $313 found 4 hours ago
Spirit Airlines
Fri, Oct 31 - Wed, Nov 5
MDE
Medellin
CLT
Charlotte
$318 Roundtrip, found 6 days ago
$318
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Fri, Oct 31 from Medellin to Charlotte, returning Wed, Nov 5, priced at $318 found 6 days ago
American Airlines
Mon, Dec 22 - Wed, Dec 31
MDE
Medellin
CLT
Charlotte
$469 Roundtrip, found 1 day ago
$469
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Dec 22 from Medellin to Charlotte, returning Wed, Dec 31, priced at $469 found 1 day ago
United
Mon, Nov 24 - Mon, Dec 29
MDE
Medellin
CLT
Charlotte
$474 Roundtrip, just found
$474
Roundtrip
just found
Select United flight, departing Mon, Nov 24 from Medellin to Charlotte, returning Mon, Dec 29, priced at $474 just found
Delta
Sun, Nov 9 - Mon, Dec 8
MDE
Medellin
CLT
Charlotte
$492 Roundtrip, found 8 hours ago
$492
Roundtrip
found 8 hours ago
Select Delta flight, departing Sun, Nov 9 from Medellin to Charlotte, returning Mon, Dec 8, priced at $492 found 8 hours ago
LATAM Airlines Group
Wed, Dec 17 - Mon, Jan 19
MDE
Medellin
CLT
Charlotte
$502 Roundtrip, found 6 days ago
$502
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Wed, Dec 17 from Medellin to Charlotte, returning Mon, Jan 19, priced at $502 found 6 days ago

Find the cheapest month to fly from Medellín (MDE) to Charlotte (CLT)

February is typically the cheapest month to fly

From $295 - $1,000 per traveler.

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT) cost?
Lock in a cheap one-way flight from $186 or cheap return flight from $270 from Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT)?
October is the cheapest month to fly from MDE to CLT. Traveling during quieter months is often the key to scoring lower fares.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest MDE to CLT flight.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT)?
You'll have to catch a flight with a layover when traveling from Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from MDE to CLT?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT)?
To avoid potential delays on the Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT) route, fly before 3 PM. Flights after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT) last-minute?
Holding off until just before your trip to book your flight from MDE to CLT often results in higher prices. While it's possible to find some last-minute discounts, they're not always guaranteed. Be flexible with your itinerary to maximize your chances of landing a bargain.
Is it cheaper to book a MDE to CLT flight and hotel package?
You can save money by booking a MDE to CLT flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. Once you've chosen your preferred flights and accommodations, consider other add-ons like activities, car rentals and tours.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Charlotte-Douglas Intl. Airport (CLT)?
Typically, you can cancel or modify your MDE to CLT flight. However, there may be additional fees, especially if you made your booking over 24 hours ago. Check your itinerary for the airline's policies and fees on flight changes, or if you'd like further details, visit our Customer Service portal.

Travel information

Travel information

Origin airport
José María Córdova Intl.
Destination airport
Charlotte-Douglas Intl.
Airlines serving
Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, Spirit Airlines, United
Roundtrip price
$269
Distance
2037 mi

Book with confidence

Book with confidence

Medellín to Charlotte Flights

The cheapest times to fly from Medellín to Charlotte

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Charlotte are during the month of October. You can find some of the cheapest flights from Medellín to Charlotte with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Charlotte

Sunday is one of the best days to book for cheap flights from Medellín to Charlotte: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Charlotte

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Charlotte in 2025. You can also book with separate airlines for your outbound and return journeys, from $186 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Charlotte flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Charlotte airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Medellín to Charlotte Flights

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Explore a world of travel with Expedia

*Available to One Key members.