$747 Cheap Flights from Medellín (MDE) to Prague (PRG)

View $747 flight on Sun, Feb 22, 2026Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Vaclav Havel Airport (PRG)

Cheap Flights from Medellín to Prague (MDE-PRG)

Prices were available within the past 7 days and start at $747 for one-way flights and $1,050 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Thu, Nov 13 - Thu, Dec 4
MDE
Medellin
PRG
Prague
$1,050 Roundtrip, found 3 days ago
$1,050
Roundtrip
found 3 days ago
Select United flight, departing Thu, Nov 13 from Medellin to Prague, returning Thu, Dec 4, priced at $1,050 found 3 days ago
United
Thu, Nov 13 - Mon, Nov 24
MDE
Medellin
PRG
Prague
$1,058 Roundtrip, found 3 days ago
$1,058
Roundtrip
found 3 days ago
Select United flight, departing Thu, Nov 13 from Medellin to Prague, returning Mon, Nov 24, priced at $1,058 found 3 days ago
United
Wed, Feb 25 - Mon, Mar 2
MDE
Medellin
PRG
Prague
$1,060 Roundtrip, found 4 days ago
$1,060
Roundtrip
found 4 days ago
Select United flight, departing Wed, Feb 25 from Medellin to Prague, returning Mon, Mar 2, priced at $1,060 found 4 days ago
United
Wed, Nov 19 - Fri, Dec 5
MDE
Medellin
PRG
Prague
$1,073 Roundtrip, found 3 days ago
$1,073
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 19 from Medellin to Prague, returning Fri, Dec 5, priced at $1,073 found 3 days ago
United
Thu, Nov 13 - Sun, Nov 23
MDE
Medellin
PRG
Prague
$1,078 Roundtrip, found 3 days ago
$1,078
Roundtrip
found 3 days ago
Select United flight, departing Thu, Nov 13 from Medellin to Prague, returning Sun, Nov 23, priced at $1,078 found 3 days ago
United
Thu, Feb 19 - Thu, Feb 26
MDE
Medellin
PRG
Prague
$1,080 Roundtrip, found 4 days ago
$1,080
Roundtrip
found 4 days ago
Select United flight, departing Thu, Feb 19 from Medellin to Prague, returning Thu, Feb 26, priced at $1,080 found 4 days ago
Copa
Mon, Feb 23 - Thu, Feb 26
MDE
Medellin
PRG
Prague
$1,165 Roundtrip, found 4 days ago
$1,165
Roundtrip
found 4 days ago
Select Copa flight, departing Mon, Feb 23 from Medellin to Prague, returning Thu, Feb 26, priced at $1,165 found 4 days ago
KLM
Mon, Feb 23 - Wed, Feb 25
MDE
Medellin
PRG
Prague
$1,345 Roundtrip, found 4 days ago
$1,345
Roundtrip
found 4 days ago
Select KLM flight, departing Mon, Feb 23 from Medellin to Prague, returning Wed, Feb 25, priced at $1,345 found 4 days ago
Turkish Airlines
Sun, Feb 22 - Tue, Feb 24
MDE
Medellin
PRG
Prague
$1,347 Roundtrip, found 4 days ago
$1,347
Roundtrip
found 4 days ago
Select Turkish Airlines flight, departing Sun, Feb 22 from Medellin to Prague, returning Tue, Feb 24, priced at $1,347 found 4 days ago
Lufthansa
Fri, Nov 7 - Fri, Nov 14
MDE
Medellin
PRG
Prague
$1,547 Roundtrip, found 2 days ago
$1,547
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Fri, Nov 7 from Medellin to Prague, returning Fri, Nov 14, priced at $1,547 found 2 days ago

Alternative airports near Prague

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Vaclav Havel PRG. Cheapest and Closest option available. Average driving time to city center is 19 minutes. Flights from $1,345
PRG
Vaclav Havel
CheapestClosest
Average driving time to city center19 min
Flights from $1,345

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Vaclav Havel Airport (PRG) cost?
Lock in a cheap one-way flight from $747 or cheap return flight from $1,050 from Jose Maria Cordova Intl. Airport (MDE) to Vaclav Havel Airport (PRG) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Vaclav Havel Airport (PRG)?
November is the least expensive month to fly from MDE to PRG. Traveling during quieter months is often the key to finding better deals on flights.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Vaclav Havel Airport (PRG)?
To find the cheapest airline that'll fly you from MDE to PRG, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Vaclav Havel Airport (PRG)?
You'll need to hop on a flight with a layover when traveling from Jose Maria Cordova Intl. Airport (MDE) to Vaclav Havel Airport (PRG). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from MDE to PRG?
Typically you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Vaclav Havel Airport (PRG)?
To arrive at Vaclav Havel Airport (PRG) on time, select a flight that leaves Jose Maria Cordova Intl. Airport (MDE) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Vaclav Havel Airport (PRG) last-minute?
Waiting until just before your departure to book a ticket from MDE to PRG often results in higher prices. While it's possible to find some last-minute deals, there's no guarantee. Keep your travel schedule open for the best chance of getting a bargain.
Is it cheaper to book a MDE to PRG flight and hotel package?
Compared with arranging flights and hotels separately, booking a MDE to PRG flight and hotel package with Expedia could result in significant savings. What's more, managing everything in one place takes the hassle out of planning your trip. Simply secure your flights and select from our wide range of hotels, then personalize your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Vaclav Havel Airport (PRG)?
Typically, you can cancel or modify your MDE to PRG flight. However, there may be additional charges, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you want more information, head to our Customer Service portal.

Travel information

Origin airport
José María Córdova Intl.
Destination airport
Vaclav Havel
Airlines serving
American Airlines, Iberia, KLM, LATAM Airlines Group, Lufthansa, Turkish Airlines, United
Roundtrip price
$1,050
Distance
5877 mi

Book with confidence

Medellín to Prague Flights

The cheapest times to fly from Medellín to Prague

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Prague are during the month of November. You can find some of the cheapest flights from Medellín to Prague with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Prague

Sunday is one of the best days to book for cheap flights from Medellín to Prague: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Prague

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Prague in 2025. You can also book with separate airlines for your outbound and return journeys, from $747 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Prague flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Prague airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Medellín to Prague Flights

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*Available to One Key members.