$309 Cheap Flights from Medellín (MDE) to Salta (SLA)

View $309 flight on Sat, Dec 20, 2025Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Salta (SLA-Martín Miguel de Güemes Intl.)

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Cheap Flights from Medellín to Salta (MDE-SLA)

Prices were available within the past 7 days and start at $309 for one-way flights and $871 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Fri, Dec 19 - Tue, Jan 13
MDE
Medellin
SLA
Salta
$871 Roundtrip, found 2 days ago
$871
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Fri, Dec 19 from Medellin to Salta, returning Tue, Jan 13, priced at $871 found 2 days ago
LATAM Airlines Group
Mon, Dec 22 - Tue, Jan 13
MDE
Medellin
SLA
Salta
$883 Roundtrip, found 2 days ago
$883
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 22 from Medellin to Salta, returning Tue, Jan 13, priced at $883 found 2 days ago
LATAM Airlines Group
Fri, Dec 19 - Sun, Jan 11
MDE
Medellin
SLA
Salta
$971 Roundtrip, found 2 days ago
$971
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Fri, Dec 19 from Medellin to Salta, returning Sun, Jan 11, priced at $971 found 2 days ago
LATAM Airlines Group
Mon, Dec 22 - Sun, Jan 11
MDE
Medellin
SLA
Salta
$983 Roundtrip, found 2 days ago
$983
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 22 from Medellin to Salta, returning Sun, Jan 11, priced at $983 found 2 days ago
LATAM Airlines Group
Fri, Dec 19 - Wed, Jan 14
MDE
Medellin
SLA
Salta
$1,002 Roundtrip, found 2 days ago
$1,002
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Fri, Dec 19 from Medellin to Salta, returning Wed, Jan 14, priced at $1,002 found 2 days ago
LATAM Airlines Group
Mon, Dec 22 - Wed, Jan 14
MDE
Medellin
SLA
Salta
$1,014 Roundtrip, found 2 days ago
$1,014
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 22 from Medellin to Salta, returning Wed, Jan 14, priced at $1,014 found 2 days ago
LATAM Airlines Group
Sun, Dec 21 - Tue, Jan 13
MDE
Medellin
SLA
Salta
$1,028 Roundtrip, found 2 days ago
$1,028
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Sun, Dec 21 from Medellin to Salta, returning Tue, Jan 13, priced at $1,028 found 2 days ago
Copa
Thu, Dec 25 - Wed, Jan 14
MDE
Medellin
SLA
Salta
$1,074 Roundtrip, found 2 days ago
$1,074
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Dec 25 from Medellin to Salta, returning Wed, Jan 14, priced at $1,074 found 2 days ago
Aerolineas Argentinas
Wed, Dec 24 - Mon, Jan 12
MDE
Medellin
SLA
Salta
$1,254 Roundtrip, found 2 days ago
$1,254
Roundtrip
found 2 days ago
Select Aerolineas Argentinas flight, departing Wed, Dec 24 from Medellin to Salta, returning Mon, Jan 12, priced at $1,254 found 2 days ago
avianca
Mon, Dec 22 - Sun, Jan 11
MDE
Medellin
SLA
Salta
$1,336 Roundtrip, found 2 days ago
$1,336
Roundtrip
found 2 days ago
Select avianca flight, departing Mon, Dec 22 from Medellin to Salta, returning Sun, Jan 11, priced at $1,336 found 2 days ago
Flights from Medellín (MDE) to Salta (SLA)
Origin airport
José María Córdova Intl.
Destination airport
Martín Miguel de Güemes Intl.
Roundtrip price
$871
Distance
2244 mi

Medellín to Salta Flights

The cheapest times to fly from Medellín to Salta

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Salta are during the month of December. You can find some of the cheapest flights from Medellín to Salta with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Salta

Sunday is one of the best days to book for cheap flights from Medellín to Salta: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Salta

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Salta in 2025. You can also book with separate airlines for your outbound and return journeys, from $309 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Salta flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Salta airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Martin Miguel de Guemes Intl. Airport (SLA) cost?
Lock in a cheap one-way flight from $309 or cheap return flight from $871 from Jose Maria Cordova Intl. Airport (MDE) to Martin Miguel de Guemes Intl. Airport (SLA) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Martin Miguel de Guemes Intl. Airport (SLA)?
Planning your getaway for December may help you find better deals, as it's the cheapest month for flights between MDE and SLA. You'll usually find the lowest fares during the off-season.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Martin Miguel de Guemes Intl. Airport (SLA)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest MDE to SLA flight.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Martin Miguel de Guemes Intl. Airport (SLA)?
You'll need to hop on a flight with a layover if you're traveling from Jose Maria Cordova Intl. Airport (MDE) to Martin Miguel de Guemes Intl. Airport (SLA). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from MDE to SLA?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Martin Miguel de Guemes Intl. Airport (SLA)?
To avoid potential delays on the Jose Maria Cordova Intl. Airport (MDE) to Martin Miguel de Guemes Intl. Airport (SLA) route, aim to travel before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Martin Miguel de Guemes Intl. Airport (SLA) last-minute?
Holding off until right before your break to book your flight from MDE to SLA often results in higher prices. While you might find some last-minute discounts, there's no guarantee. Keep your travel plans flexible to boost your chances of getting a bargain.
Is it cheaper to book a MDE to SLA flight and hotel package?
Booking a MDE to SLA flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our wide range of accommodations and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Martin Miguel de Guemes Intl. Airport (SLA)?
It's usually possible to cancel or reschedule your MDE to SLA flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.