$231 Cheap Flights from Harrisburg (MDT) to Greenville (GSP)
Popular airlines from Harrisburg Intl. Airport (MDT) to Greenville-Spartanburg Intl. Airport (GSP)
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Cheap Flights from Harrisburg to Greenville (MDT-GSP)
Alternative airports near Greenville
Prices were available within the past 7 days. Prices and availability are subject to change.
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Harrisburg (MDT) to Greenville (GSP) at a glance
Travel between Harrisburg (MDT) and Greenville (GSP) with a range of airlines on this domestic short-haul route. You can compare various options from full-service carriers to find the best fit for your budget and schedule while planning your visit to discover Greenville's renowned attractions and neighborhoods. Check out all the essential details for flights from Harrisburg International Airport (MDT) to Greenville-Spartanburg International Airport (GSP).
- Fastest flight duration: around 2h 45m in-flight, plus roughly 1h 15m layover with one stop
- Route distance: roughly 450 miles (725 km)
- Flights per week: around 8 departures on average
- Typical fares (one-way): economy tickets often range from $115–$405, depending on seasonality and how far ahead you book
Flights from Harrisburg International Airport (MDT) to Greenville-Spartanburg International Airport (GSP)
Based on recent traveler bookings, here are the top airlines favored for flights from Harrisburg to Greenville, typically featuring one-stop services. Many routes include popular layovers at Charlotte-Douglas International Airport (CLT) with a layover of around 1 hour, Philadelphia International Airport (PHL) with about a 1 hour and 15-minute layover, and Washington Dulles International Airport (IAD), also approximately 1 hour and 15 minutes. This offers you the flexibility to mix and match pricing, total travel time, and cabin class for the ideal itinerary.
- American Airlines: This full-service airline provides one-stop travel options, with one-way ticket prices generally falling between $115 and $410. It represents around 62% of flights on this route, featuring an in-flight duration of 2 hours and 45 minutes, with an overall travel time of about 4 hours, including layover.
- United: A full-service airline, United offers one-stop services with one-way fares typically ranging from $115 to $335. With approximately 20% of departures on this route, passengers can expect a flight time of 2 hours and 45 minutes and a total travel duration of roughly 4 hours, factoring in the layover.
- Delta: As a full-service carrier, Delta provides one-stop options with one-way fares usually between $115 and $350. It accounts for around 18% of departures on this route, with an in-flight time of 2 hours and 45 minutes, leading to a total journey duration of about 4 hours, including the layover.
Best time to fly from Harrisburg (MDT) to Greenville (GSP)
The most popular months for travelers flying from Harrisburg to Greenville are February, March, and June, when peak temperatures in Greenville reach up to 76.1°F in June. If you prefer quieter travel, consider December, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 45.3°F. For better deals, July usually offers the lowest average one-way fare around $189. Flight availability peaks in December, with approximately 12 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 7 flights per week.
- Cheapest time to fly: July usually offers good deals with average one-way fare around $189, roughly 16% cheaper than the yearly average.
- More budget-friendly months to fly: June, December, and February typically offer average one-way fares roughly ranging from $191 to $207.
- Most flight options: December has the highest number of flights from Harrisburg to Greenville, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
| Month | Temperature | Demand | Weekly Flights | Average one-way Fare |
| January | 41.4°F (5.2°C) | Average | 7 | $238 |
| February | 45.3°F (7.4°C) | Moderately High | 8 | $207 |
| March | 51.8°F (11.0°C) | Moderately High | 8 | $235 |
| April | 59.9°F (15.5°C) | Average | 8 | $220 |
| May | 68.4°F (20.2°C) | Moderately Low | 8 | $224 |
| June | 76.1°F (24.5°C) | Moderately High | 9 | $191 |
| July | 79.5°F (26.4°C) | Average | 9 | $189 |
| August | 77.5°F (25.3°C) | Moderately Low | 9 | $221 |
| September | 72.3°F (22.4°C) | Average | 9 | $235 |
| October | 61.9°F (16.6°C) | Average | 8 | $302 |
| November | 51.1°F (10.6°C) | Average | 8 | $234 |
| December | 45.3°F (7.4°C) | Moderately Low | 12 | $207 |
*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.
Alternative routes from Harrisburg (MDT) to Greenville (GSP)
- Harrisburg to Greenville (HAR-GSP): Capital City Airport (HAR) lies approximately 5 miles from Harrisburg International Airport (MDT).
- Harrisburg to Greenville (MDT-GMU): Greenville Downtown Airport (GMU) is located around 8 miles from Greenville-Spartanburg International Airport (GSP).
- Lancaster to Greenville (LNS-GSP): Lancaster Airport (LNS) is roughly 25 miles away from Harrisburg International Airport (MDT).
How to find the best prices for flights from Harrisburg (MDT) to Greenville (GSP)
Getting some of the best deals on flights from Harrisburg to Greenville is all about timing and flexibility. Here are some key tips to help you save:
- Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, which aligns with when most travelers make their reservations. Departures in the morning (5 am-12 pm) tend to offer lower prices and are popular among travelers. Additionally, flying on Wednesday often results in cheaper fares, although Thursday remains the most popular travel day.
- Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
- Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Greenville hotel and flight deals.
- Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
- Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
- Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.
*Members only. Savings vary and are not available on all bundles. Select hotels.
Arriving at Greenville-Spartanburg International Airport from Harrisburg International Airport
Greenville welcomes travelers from Harrisburg with a range of transport options based on price, convenience, and proximity. For departures, Harrisburg International Airport is roughly a 15-minute drive (covering about 12 miles) from central Harrisburg. Greenville city center is approximately a 20-minute drive (covering about 16 miles) from Greenville-Spartanburg International Airport, depending on traffic. Here's how to reach Greenville efficiently:
- Hotel transfer: Transfers offer a convenient way to reach your hotel in Greenville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
- Car rental: Renting a car from Greenville-Spartanburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Greenville-Spartanburg International Airport on Expedia.
- Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
Harrisburg to Greenville Flights
The cheapest times to fly from Harrisburg to Greenville
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Harrisburg to Greenville are during the month of November. You can find some of the cheapest flights from Harrisburg to Greenville with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Harrisburg to Greenville
Sunday is one of the best days to book for cheap flights from Harrisburg to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Harrisburg to Greenville
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Harrisburg to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $231 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Harrisburg to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Harrisburg to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently Asked Questions
How much does a flight from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) cost?
You can find cheap one-way flights from $231 and cheap return flights $319 Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) with Expedia. One-way flights usually range from $215 to $637, and return flights typically cost between $349 and $1039. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) ticket fares go up or down.
*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The cheapest month to fly from MDT to GSP is November when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Enter MDT to GSP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), with round-trip tickets starting from around $228 with a layover in Philadelphia Intl. (PHL). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
To find a cheap flight from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The earliest flight from Harrisburg (MDT) to Greenville (GSP) usually departs at around 5:00 AM local time, operated by American Airlines. This seasonal service is active in December, giving you an early start to your trip. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The most popular departure times for flights from Harrisburg Intl. (MDT) to Greenville-Spartanburg Intl. (GSP) are in the morning, from 6am to 9am. About 34% of passengers prefer this time window. Many major carriers, including American Airlines, Delta and United, offer flights during this window. This timing is popular because it allows you to arrive in Greenville early and make the most of your day.
How long does it take to fly from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Flying from MDT to GSP with a connection usually takes about 3 hours 50 minutes, traveling roughly 473 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
First class seats are offered on the MDT to GSP route. First class cabins are available on:
- American Airlines
- Delta Air Lines
- United Airlines
How do I earn miles on a Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight with Expedia?
It's easy to earn miles on a Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.
*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Greenville from Harrisburg Intl. (MDT)?
From Harrisburg Intl. (MDT), you can fly into Pitt-Greenville (PGV) and Greenville-Spartanburg Intl. (GSP) in Greenville. Some flights may connect through major hubs like Logan Intl. (BOS) before reaching Greenville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) at the last minute?
Typically, booking a last minute flight from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package?
Securing a Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
If you booked your Harrisburg, PA (MDT-Harrisburg Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.
Travel information
Origin airport | Harrisburg Intl. Airport |
|---|---|
Destination airport | Greenville-Spartanburg Intl. Airport |
Distance | 472 miles away |
Airlines serving | American Airlines, Delta, United |
Popular airline | American Airlines |
Roundtrip price | $319 |