$758 Cheap Flights from Medford (MFR) to Johannesburg (JNB)

View $758 flight on Mon, Jan 26, 2026Opens in a new window

Popular airlines from Rogue Valley Intl. Airport (MFR) to O.R. Tambo Intl. Airport (JNB)

Cheap Flights from Medford to Johannesburg (MFR-JNB)

Prices were available within the past 7 days and start at $758 for one-way flights and $1,235 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Mon, Mar 16 - Mon, Mar 30
MFR
Medford
JNB
Johannesburg
$1,235 Roundtrip, found 2 days ago
$1,235
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Mar 16 from Medford to Johannesburg, returning Mon, Mar 30, priced at $1,235 found 2 days ago
American Airlines
Mon, Nov 24 - Wed, Dec 3
MFR
Medford
JNB
Johannesburg
$1,260 Roundtrip, found 21 hours ago
$1,260
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Mon, Nov 24 from Medford to Johannesburg, returning Wed, Dec 3, priced at $1,260 found 21 hours ago
American Airlines
Thu, Apr 9 - Thu, Apr 23
MFR
Medford
JNB
Johannesburg
$1,266 Roundtrip, found 2 hours ago
$1,266
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Apr 9 from Medford to Johannesburg, returning Thu, Apr 23, priced at $1,266 found 2 hours ago
American Airlines
Wed, Mar 11 - Mon, Mar 30
MFR
Medford
JNB
Johannesburg
$1,310 Roundtrip, found 2 days ago
$1,310
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Mar 11 from Medford to Johannesburg, returning Mon, Mar 30, priced at $1,310 found 2 days ago
American Airlines
Thu, Apr 9 - Thu, Apr 23
MFR
Medford
JNB
Johannesburg
$1,360 Roundtrip, found 2 hours ago
$1,360
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Apr 9 from Medford to Johannesburg, returning Thu, Apr 23, priced at $1,360 found 2 hours ago
American Airlines
Fri, Nov 28 - Wed, Dec 3
MFR
Medford
JNB
Johannesburg
$1,410 Roundtrip, found 21 hours ago
$1,410
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Fri, Nov 28 from Medford to Johannesburg, returning Wed, Dec 3, priced at $1,410 found 21 hours ago
Qatar Airways
Thu, Apr 9 - Thu, Apr 23
MFR
Medford
JNB
Johannesburg
$1,435 Roundtrip, found 2 hours ago
$1,435
Roundtrip
found 2 hours ago
Select Qatar Airways flight, departing Thu, Apr 9 from Medford to Johannesburg, returning Thu, Apr 23, priced at $1,435 found 2 hours ago
British Airways
Sun, Nov 23 - Mon, Dec 1
MFR
Medford
JNB
Johannesburg
$1,463 Roundtrip, found 21 hours ago
$1,463
Roundtrip
found 21 hours ago
Select British Airways flight, departing Sun, Nov 23 from Medford to Johannesburg, returning Mon, Dec 1, priced at $1,463 found 21 hours ago
Alaska Airlines
Sat, Mar 14 - Tue, Mar 31
MFR
Medford
JNB
Johannesburg
$1,464 Roundtrip, found 1 day ago
$1,464
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Sat, Mar 14 from Medford to Johannesburg, returning Tue, Mar 31, priced at $1,464 found 1 day ago
United
Thu, Apr 9 - Thu, Apr 23
MFR
Medford
JNB
Johannesburg
$1,712 Roundtrip, found 2 hours ago
$1,712
Roundtrip
found 2 hours ago
Select United flight, departing Thu, Apr 9 from Medford to Johannesburg, returning Thu, Apr 23, priced at $1,712 found 2 hours ago

Frequently asked questions

How much does a flight from Rogue Valley Intl. Airport (MFR) to O.R. Tambo Intl. Airport (JNB) cost?
Get a cheap one-way flight from $758 or cheap return flight from $1,235 from Rogue Valley Intl. Airport (MFR) to O.R. Tambo Intl. Airport (JNB) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Rogue Valley Intl. Airport (MFR) to O.R. Tambo Intl. Airport (JNB)?
March is the cheapest month to fly from MFR to JNB. Planning your trip for the off-season is often the key to finding a great deal.
What is the cheapest airline that flies from Rogue Valley Intl. Airport (MFR) to O.R. Tambo Intl. Airport (JNB)?
To find the cheapest airline that'll fly you from MFR to JNB, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Rogue Valley Intl. Airport (MFR) to O.R. Tambo Intl. Airport (JNB)?
There are no daily nonstop flights from Rogue Valley Intl. Airport (MFR) to O.R. Tambo Intl. Airport (JNB). But you can book flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way in no time.
What day of the week has the most flights from MFR to JNB?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on a range of factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Rogue Valley Intl. Airport (MFR) to O.R. Tambo Intl. Airport (JNB)?
To land at O.R. Tambo Intl. Airport (JNB) on time, pick a flight that leaves Rogue Valley Intl. Airport (MFR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Rogue Valley Intl. Airport (MFR) to O.R. Tambo Intl. Airport (JNB) last-minute?
Waiting until just before your departure to book a flight from MFR to JNB often results in higher prices. Although you may find some last-minute offers, there's no guarantee. Keep your travel plans flexible to boost your chances of snagging a bargain.
Is it cheaper to book a MFR to JNB flight and hotel package?
Securing a MFR to JNB flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Choose from our impressive range of stays and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Rogue Valley Intl. Airport (MFR) to O.R. Tambo Intl. Airport (JNB)?
In most instances, you're able to reschedule or cancel your MFR to JNB flight. However, there may be additional charges, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you want more information, go to our Customer Service portal.

Travel information

Origin airport
Rogue Valley Intl.
Destination airport
O.R. Tambo Intl.
Airlines serving
Air France, American Airlines, British Airways, Delta, KLM, Qatar Airways, United, Virgin Atlantic
Roundtrip price
$1,235
Distance
10456 mi

Book with confidence

Medford to Johannesburg Flights

The cheapest times to fly from Medford to Johannesburg

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medford to Johannesburg are during the month of March. You can find some of the cheapest flights from Medford to Johannesburg with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medford to Johannesburg

Sunday is one of the best days to book for cheap flights from Medford to Johannesburg: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medford to Johannesburg

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medford to Johannesburg in 2025. You can also book with separate airlines for your outbound and return journeys, from $758 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medford to Johannesburg flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medford to Johannesburg airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Medford to Johannesburg Flights

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*Available to One Key members.