$243 Cheap Flights from Mobile (MOB) to Columbus (CMH)

View $243 flight on Tue, Jun 30, 2026Opens in a new window

Popular airlines from Mobile Regional Airport (MOB) to John Glenn Columbus Intl. Airport (CMH)

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Cheap Flights from Mobile to Columbus (MOB-CMH)

Prices were available within the past 7 days and start at $243 for one-way flights and $309 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Nov 11 - Tue, Nov 17
MOB
Mobile
CMH
Columbus
$309 Roundtrip, found 2 days ago
$309
Roundtrip
found 2 days ago
Select United flight, departing Wed, Nov 11 from Mobile to Columbus, returning Tue, Nov 17, priced at $309 found 2 days ago
American Airlines
Wed, Nov 11 - Tue, Nov 17
MOB
Mobile
CMH
Columbus
$311 Roundtrip, found 2 days ago
$311
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Nov 11 from Mobile to Columbus, returning Tue, Nov 17, priced at $311 found 2 days ago
United
Wed, Nov 11 - Tue, Nov 17
MOB
Mobile
CMH
Columbus
$314 Roundtrip, found 2 days ago
$314
Roundtrip
found 2 days ago
Select United flight, departing Wed, Nov 11 from Mobile to Columbus, returning Tue, Nov 17, priced at $314 found 2 days ago
American Airlines
Wed, Aug 5 - Mon, Aug 10
MOB
Mobile
CMH
Columbus
$317 Roundtrip, found 8 hours ago
$317
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Aug 5 from Mobile to Columbus, returning Mon, Aug 10, priced at $317 found 8 hours ago
American Airlines
Wed, Jun 24 - Sun, Jun 28
MOB
Mobile
CMH
Columbus
$323 Roundtrip, found 10 hours ago
$323
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Jun 24 from Mobile to Columbus, returning Sun, Jun 28, priced at $323 found 10 hours ago
Delta
Fri, Jan 1 - Tue, Jan 5
MOB
Mobile
CMH
Columbus
$345 Roundtrip, found 3 days ago
$345
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Jan 1 from Mobile to Columbus, returning Tue, Jan 5, priced at $345 found 3 days ago
Delta
Wed, Aug 5 - Mon, Aug 10
MOB
Mobile
CMH
Columbus
$351 Roundtrip, found 8 hours ago
$351
Roundtrip
found 8 hours ago
Select Delta flight, departing Wed, Aug 5 from Mobile to Columbus, returning Mon, Aug 10, priced at $351 found 8 hours ago
Delta
Fri, Aug 14 - Mon, Aug 17
MOB
Mobile
CMH
Columbus
$361 Roundtrip, found 2 days ago
$361
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Aug 14 from Mobile to Columbus, returning Mon, Aug 17, priced at $361 found 2 days ago
United
Thu, Aug 13 - Sun, Aug 16
MOB
Mobile
CMH
Columbus
$362 Roundtrip, found 2 days ago
$362
Roundtrip
found 2 days ago
Select United flight, departing Thu, Aug 13 from Mobile to Columbus, returning Sun, Aug 16, priced at $362 found 2 days ago
Delta
Fri, Oct 16 - Mon, Oct 19
MOB
Mobile
CMH
Columbus
$365 Roundtrip, found 2 days ago
$365
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Oct 16 from Mobile to Columbus, returning Mon, Oct 19, priced at $365 found 2 days ago

What you need to know for your flight from Mobile Regional to John Glenn Columbus Intl.

Mobile (MOB) to Columbus (CMH) at a glance

Travel between Mobile (MOB) and Columbus (CMH) with a range of airlines on this domestic short-haul route. Explore various options for Mobile to Columbus flights, comparing full-service carriers to identify the itinerary that aligns with your budget and schedule. As you prepare to discover the iconic sights and neighborhoods of Columbus, gather essential information about flights from Mobile Regional Airport (MOB) to John Glenn Columbus International Airport (CMH).

  • Fastest flight duration: around 3h 15m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 700 miles (1,130 km)
  • Flights per week: around 7 departures on average
  • Typical fares (one-way): economy tickets often range from $125–$450, depending on seasonality and how far ahead you book

Flights from Mobile Regional Airport (MOB) to John Glenn Columbus International Airport (CMH)

Based on recent traveler bookings, here are the top airlines favored for one-stop flights from Mobile to Columbus. Many passengers opt for routes with layovers at Hartsfield-Jackson Atlanta International Airport (ATL, approximately 1 hour and 30 minutes), Charlotte-Douglas International Airport (CLT, around 55 minutes), and Washington Dulles International Airport (IAD, about 1 hour and 30 minutes). These options provide the flexibility to choose between price, total travel time, and cabin class, helping you find the perfect itinerary.

  • Delta: As a comprehensive airline, Delta provides a one-stop service with one-way fares generally falling between $125 and $815. It represents around 53% of the departures from this route, featuring an in-flight duration of 3 hours and 15 minutes, while the entire trip, including layover time, spans approximately 4 hours and 45 minutes.
  • American Airlines: Another full-service option, American Airlines offers one-stop travel with one-way ticket prices usually ranging from $125 to $510. This airline covers about 25% of the flights on this route, with a flying time of 3 hours and 15 minutes and a total travel duration, including layovers, of roughly 4 hours and 45 minutes.
  • United: United is a full-service airline that also provides one-stop service, with one-way fares typically ranging from $130 to $405. It accounts for approximately 22% of departures on this route, featuring a flight time of 3 hours and 15 minutes and an overall journey time of about 4 hours and 45 minutes, including layovers.

Travelers have the option to upgrade their flight from Mobile to Columbus, with Delta providing first-class service on this route.

Best time to fly from Mobile (MOB) to Columbus (CMH)

The most popular months for travelers flying from Mobile to Columbus are March, May, and August, when peak temperatures in Columbus reach up to 73°F in August. If you prefer quieter travel, consider June, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 70.9°F. For better deals, July usually offers the lowest average one-way fare around $158. Flight availability peaks in October, with approximately 9 flights per week, making it easier to find convenient departure times. February, March, April, May, July, September, and December have the fewest flights, with approximately 7 flights per week.

  • Cheapest time to fly: July usually offers good deals with average one-way fare around $158, roughly 46% cheaper than the yearly average.
  • Most flight options: October has the highest number of flights from Mobile to Columbus, with approximately 9 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January28.6°F (-1.9°C)Average8$347
February31.5°F (-0.3°C)Low7$440
March41.7°F (5.4°C)High7$378
April52.0°F (11.1°C)Average7$287
May63.1°F (17.3°C)High7$297
June70.9°F (21.6°C)Low8$236
July74.7°F (23.7°C)Average7$158
August73.0°F (22.8°C)High8$252
September67.3°F (19.6°C)Average7$253
October55.8°F (13.2°C)Average9$263
November43.2°F (6.2°C)Low8$355
December35.4°F (1.9°C)Average7$310

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Mobile (MOB) to Columbus (CMH)

  • Pensacola to Columbus (PNS-CMH): Located approximately 64 miles from Mobile Regional Airport (MOB), Pensacola International Airport (PNS) offers a variety of travel options. One-way economy tickets on this route generally fall between $120 and $380, influenced by the season and how far in advance you book. Flights typically require one stop, with common layover points at Hartsfield-Jackson Atlanta International Airport (ATL) and Charlotte-Douglas International Airport (CLT). Major airlines operating on this route include Delta and American Airlines, with business and first-class service also available.

How to find the best prices for flights from Mobile (MOB) to Columbus (CMH)

Getting some of the best deals on flights from Mobile to Columbus is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are generally available when booking 2-8 weeks in advance, although most travelers tend to book within 2 weeks. Afternoon departures (12pm-6pm) usually offer lower prices, while morning flights (5am-12pm) remain the most popular. Additionally, flying on Fridays provides both cheaper fares and increased travel demand.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at John Glenn Columbus International Airport from Mobile Regional Airport

Columbus welcomes travelers from Mobile with a range of transport options based on price, convenience, and proximity. Here's how to reach Columbus efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Columbus, with private rides that can be arranged in advance.
  • Car rental: Renting a car from John Glenn Columbus International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at John Glenn Columbus International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From John Glenn Columbus International Airport, Columbus Bus Station, a bus station, is located about 8.6 miles from the airport and is typically reached by car.

Frequently asked questions

How much does a flight from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) cost?
You can find cheap one-way flights from $243 and cheap return flights from $309 Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) with Expedia. One-way flights typically cost between $242 and $710, and return flights often range between $326 and $1073. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
April is the cheapest month to fly from Mobile (MOB) to Columbus (CMH), with average return fares around $304. This price is about 16% lower than the average for the year, as spring travel often sees reduced demand. Other affordable months to consider are July and September.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
Enter MOB to CMH and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Mobile, AL (MOB) to Columbus, OH (CMH), with round-trip tickets starting from around $248. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
To find a cheap flight from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
The best times to fly from Mobile, AL (MOB) to Columbus, OH (CMH) are April and September. Average return flight prices are around $304, making these months both affordable and convenient. These months typically see less travel demand, allowing for a smoother journey.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
The earliest flight from Mobile, AL (MOB) to Columbus, OH (CMH) generally departs at around 5:05 AM, operated by American Airlines. This seasonal service is available in November, allowing you to make the most of your travel day. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
The most popular departure times for flights from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) are in the early morning, from 6am to 9am. This time window accounts for about 24% of total traffic. Many major carriers, including Delta and United, offer flights during this period. Early departures are favored as they allow you to arrive in Columbus with plenty of time to explore the city.
How long does it take to fly from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
Flights from MOB to CMH with one stop typically take around 5 hours 20 minutes, covering approximately 711 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
First class seats are offered on the MOB to CMH route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight with Expedia?
It's easy to earn miles on a Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Columbus from Mobile Regional (MOB)?
From Mobile Regional (MOB), you can fly into John Glenn Columbus Intl. (CMH) and Columbus Metropolitan (CSG) in Columbus. Some flights may connect through major hubs like George Bush Intercontinental (IAH), Washington Dulles Intl. (IAD), Charlotte-Douglas Intl. (CLT) before reaching Columbus. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) at the last minute?
Typically, booking a last minute flight from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight and hotel package?
Securing a Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) Columbus Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
If you booked your Mobile, AL (MOB-Mobile Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mobile Regional
Destination airport
John Glenn Columbus Intl.
Roundtrip price
$308
Distance
710 mi

Book with confidence

Mobile to Columbus Flights

The cheapest times to fly from Mobile to Columbus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mobile to Columbus are during the month of November. You can find some of the cheapest flights from Mobile to Columbus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mobile to Columbus

Sunday is one of the best days to book for cheap flights from Mobile to Columbus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mobile to Columbus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mobile to Columbus in 2026. You can also book with separate airlines for your outbound and return journeys, from $243 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mobile to Columbus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mobile to Columbus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mobile to Columbus Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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