$416 Cheap Flights from Myrtle Beach (MYR) to Prague (PRG)

View $416 flight on Wed, Jan 14, 2026Opens in a new window

Popular airlines from Myrtle Beach to Prague (PRG-Vaclav Havel)

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Cheap Flights from Myrtle Beach to Prague (MYR-PRG)

Prices were available within the past 7 days and start at $416 for one-way flights and $559 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Apr 3 - Fri, Apr 10
MYR
Myrtle Beach
PRG
Prague
$559 Roundtrip, found 20 hours ago
$559
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Fri, Apr 3 from Myrtle Beach to Prague, returning Fri, Apr 10, priced at $559 found 20 hours ago
Delta
Tue, Dec 30 - Tue, Jan 13
MYR
Myrtle Beach
PRG
Prague
$708 Roundtrip, found 3 days ago
$708
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Dec 30 from Myrtle Beach to Prague, returning Tue, Jan 13, priced at $708 found 3 days ago
British Airways
Thu, Jan 15 - Thu, Jan 22
MYR
Myrtle Beach
PRG
Prague
$711 Roundtrip, found 1 day ago
$711
Roundtrip
found 1 day ago
Select British Airways flight, departing Thu, Jan 15 from Myrtle Beach to Prague, returning Thu, Jan 22, priced at $711 found 1 day ago
United
Wed, Dec 31 - Mon, Jan 12
MYR
Myrtle Beach
PRG
Prague
$715 Roundtrip, found 3 days ago
$715
Roundtrip
found 3 days ago
Select United flight, departing Wed, Dec 31 from Myrtle Beach to Prague, returning Mon, Jan 12, priced at $715 found 3 days ago
United
Wed, Dec 31 - Sat, Jan 17
MYR
Myrtle Beach
PRG
Prague
$716 Roundtrip, found 3 days ago
$716
Roundtrip
found 3 days ago
Select United flight, departing Wed, Dec 31 from Myrtle Beach to Prague, returning Sat, Jan 17, priced at $716 found 3 days ago
Delta
Fri, Apr 3 - Fri, Apr 10
MYR
Myrtle Beach
PRG
Prague
$718 Roundtrip, found 20 hours ago
$718
Roundtrip
found 20 hours ago
Select Delta flight, departing Fri, Apr 3 from Myrtle Beach to Prague, returning Fri, Apr 10, priced at $718 found 20 hours ago
Delta
Fri, Apr 3 - Fri, Apr 10
MYR
Myrtle Beach
PRG
Prague
$724 Roundtrip, found 20 hours ago
$724
Roundtrip
found 20 hours ago
Select Delta flight, departing Fri, Apr 3 from Myrtle Beach to Prague, returning Fri, Apr 10, priced at $724 found 20 hours ago
American Airlines
Fri, Apr 3 - Fri, Apr 10
MYR
Myrtle Beach
PRG
Prague
$727 Roundtrip, found 20 hours ago
$727
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Fri, Apr 3 from Myrtle Beach to Prague, returning Fri, Apr 10, priced at $727 found 20 hours ago
Delta
Tue, Dec 30 - Sat, Jan 17
MYR
Myrtle Beach
PRG
Prague
$736 Roundtrip, found 3 days ago
$736
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Dec 30 from Myrtle Beach to Prague, returning Sat, Jan 17, priced at $736 found 3 days ago
KLM
Fri, Apr 3 - Fri, Apr 10
MYR
Myrtle Beach
PRG
Prague
$1,097 Roundtrip, found 20 hours ago
$1,097
Roundtrip
found 20 hours ago
Select KLM flight, departing Fri, Apr 3 from Myrtle Beach to Prague, returning Fri, Apr 10, priced at $1,097 found 20 hours ago

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Vaclav Havel Airport (PRG) cost?
Get a cheap one-way flight from $416 or cheap return flight from $559 from Myrtle Beach Intl. Airport (MYR) to Vaclav Havel Airport (PRG) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to Vaclav Havel Airport (PRG)?
April is the cheapest month to fly from MYR to PRG. Timing your trip outside of the busy season is often the key to better flight prices.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to Vaclav Havel Airport (PRG)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MYR to PRG flight.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Vaclav Havel Airport (PRG)?
Direct flights from Myrtle Beach Intl. Airport (MYR) to Vaclav Havel Airport (PRG) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MYR to PRG?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Vaclav Havel Airport (PRG)?
To avoid potential delays on the Myrtle Beach Intl. Airport (MYR) to Vaclav Havel Airport (PRG) route, aim to fly before 3 PM. Later departures are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Vaclav Havel Airport (PRG) last-minute?
Booking your plane ticket from MYR to PRG right before your trip is usually more expensive. However, if there's some wiggle room with your schedule, you could land a cheap last-minute fare.
Is it cheaper to book a MYR to PRG flight and hotel package?
You'll generally save money by booking a MYR to PRG flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. Once you've chosen your preferred accommodations and flights, consider other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Vaclav Havel Airport (PRG)?
Typically, you're able to reschedule or cancel your MYR to PRG flight. However, there may be additional charges, especially if your booking was made over 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you need further details, visit our Customer Service portal.

Travel information

Origin airport
Myrtle Beach Intl.
Destination airport
Vaclav Havel
Airlines serving
Air France, American Airlines, British Airways, Delta, KLM, United
Roundtrip price
$559
Distance
4607 mi

Book with confidence

Myrtle Beach to Prague Flights

The cheapest times to fly from Myrtle Beach to Prague

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Prague are during the month of April. You can find some of the cheapest flights from Myrtle Beach to Prague with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Prague

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Prague: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Prague

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Prague in 2026. You can also book with separate airlines for your outbound and return journeys, from $416 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Prague flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Prague airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Myrtle Beach to Prague Flights

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*Available to One Key members.