$539 Cheap Flights from Naples (NAP) to Medellín (MDE)

View $539 flight on Sun, Mar 15, 2026Opens in a new window

Popular airlines from Naples Intl. Airport (NAP) to Jose Maria Cordova Intl. Airport (MDE)

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Cheap Flights from Naples to Medellín (NAP-MDE)

Prices were available within the past 7 days and start at $539 for one-way flights and $1,114 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Sun, Mar 15 - Mon, Mar 30
NAP
Naples
MDE
Medellin
$1,114 Roundtrip, found 2 days ago
$1,114
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Sun, Mar 15 from Naples to Medellin, returning Mon, Mar 30, priced at $1,114 found 2 days ago
Lufthansa
Sun, Mar 15 - Mon, Mar 30
NAP
Naples
MDE
Medellin
$1,190 Roundtrip, found 2 days ago
$1,190
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Sun, Mar 15 from Naples to Medellin, returning Mon, Mar 30, priced at $1,190 found 2 days ago
Lufthansa
Sun, Mar 15 - Mon, Mar 30
NAP
Naples
MDE
Medellin
$1,206 Roundtrip, found 2 days ago
$1,206
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Sun, Mar 15 from Naples to Medellin, returning Mon, Mar 30, priced at $1,206 found 2 days ago
Air Europa
Sun, Mar 15 - Mon, Mar 30
NAP
Naples
MDE
Medellin
$1,228 Roundtrip, found 2 days ago
$1,228
Roundtrip
found 2 days ago
Select Air Europa flight, departing Sun, Mar 15 from Naples to Medellin, returning Mon, Mar 30, priced at $1,228 found 2 days ago
Iberia
Sun, Mar 15 - Mon, Mar 30
NAP
Naples
MDE
Medellin
$1,257 Roundtrip, found 2 days ago
$1,257
Roundtrip
found 2 days ago
Select Iberia flight, departing Sun, Mar 15 from Naples to Medellin, returning Mon, Mar 30, priced at $1,257 found 2 days ago
Iberia
Sun, Mar 15 - Mon, Mar 30
NAP
Naples
MDE
Medellin
$1,292 Roundtrip, found 2 days ago
$1,292
Roundtrip
found 2 days ago
Select Iberia flight, departing Sun, Mar 15 from Naples to Medellin, returning Mon, Mar 30, priced at $1,292 found 2 days ago
Air Europa
Sun, Mar 15 - Mon, Mar 30
NAP
Naples
MDE
Medellin
$1,297 Roundtrip, found 2 days ago
$1,297
Roundtrip
found 2 days ago
Select Air Europa flight, departing Sun, Mar 15 from Naples to Medellin, returning Mon, Mar 30, priced at $1,297 found 2 days ago
Iberia
Sun, Mar 15 - Mon, Mar 30
NAP
Naples
MDE
Medellin
$1,298 Roundtrip, found 2 days ago
$1,298
Roundtrip
found 2 days ago
Select Iberia flight, departing Sun, Mar 15 from Naples to Medellin, returning Mon, Mar 30, priced at $1,298 found 2 days ago
Swiss International Air Lines
Sun, Mar 15 - Mon, Mar 30
NAP
Naples
MDE
Medellin
$1,398 Roundtrip, found 2 days ago
$1,398
Roundtrip
found 2 days ago
Select Swiss International Air Lines flight, departing Sun, Mar 15 from Naples to Medellin, returning Mon, Mar 30, priced at $1,398 found 2 days ago
ITA Airways
Sun, Mar 15 - Mon, Mar 30
NAP
Naples
MDE
Medellin
$1,476 Roundtrip, found 2 days ago
$1,476
Roundtrip
found 2 days ago
Select ITA Airways flight, departing Sun, Mar 15 from Naples to Medellin, returning Mon, Mar 30, priced at $1,476 found 2 days ago
Flights from Naples (NAP) to Medellín (MDE)
Origin airport
Naples Intl.
Destination airport
José María Córdova Intl.
Roundtrip price
$1,114
Distance
5924 mi

Naples to Medellín Flights

The cheapest times to fly from Naples to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Naples to Medellín are during the month of March. You can find some of the cheapest flights from Naples to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Naples to Medellín

Sunday is one of the best days to book for cheap flights from Naples to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Naples to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Naples to Medellín in 2026. You can also book with separate airlines for your outbound and return journeys, from $539 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Naples to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Naples to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Naples Intl. Airport (NAP) to Jose Maria Cordova Intl. Airport (MDE) cost?
Get a cheap one-way flight from $539 or cheap return flight from $1,114 from Naples Intl. Airport (NAP) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Naples Intl. Airport (NAP) to Jose Maria Cordova Intl. Airport (MDE)?
The cheapest month to fly from NAP to MDE is March, when there's less demand. Off-peak months are typically when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Naples Intl. Airport (NAP) to Jose Maria Cordova Intl. Airport (MDE)?
Use the filters on Expedia to compare airlines and find the cheapest carrier that'll fly you from NAP to MDE. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Naples Intl. Airport (NAP) to Jose Maria Cordova Intl. Airport (MDE)?
You'll need to take a flight with a layover when traveling from Naples Intl. Airport (NAP) to Jose Maria Cordova Intl. Airport (MDE). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from NAP to MDE?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change depending on a number of factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Naples Intl. Airport (NAP) to Jose Maria Cordova Intl. Airport (MDE)?
To land at Jose Maria Cordova Intl. Airport (MDE) on schedule, pick a flight that leaves Naples Intl. Airport (NAP) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Naples Intl. Airport (NAP) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Last-minute bookings from NAP to MDE are usually more expensive. To secure the best rates, start looking for flights well ahead of time. That being said, if you're flexible with your travel dates, you may land a cheap ticket right before your journey.
Is it cheaper to book a NAP to MDE flight and hotel package?
Compared with arranging flights and hotels separately, booking a NAP to MDE flight and hotel package with Expedia could result in significant savings. Better still, having it all in one place will take the stress out of planning your trip. Just secure your flights and choose from our wide range of hotels, then customize your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Naples Intl. Airport (NAP) to Jose Maria Cordova Intl. Airport (MDE)?
In most instances, you can cancel or modify your NAP to MDE flight. However, additional charges may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you need more information, visit our Customer Service portal.

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*Available to One Key members.