$686 Cheap Flights from Porto (OPO) to São Tomé Island (TMS)

View $686 flight on Mon, Dec 29, 2025Opens in a new window

Popular airlines from Porto Airport (OPO) to São Tomé Island (TMS-São Tomé Intl.)

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Cheap Flights from Porto to São Tomé Island (OPO-TMS)

Prices were available within the past 7 days and start at $686 for one-way flights and $728 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAP Portugal
Sat, May 2 - Sat, May 16
OPO
Porto
TMS
São Tomé Island
$728 Roundtrip, found 5 days ago
$728
Roundtrip
found 5 days ago
Select TAP Portugal flight, departing Sat, May 2 from Porto to São Tomé Island, returning Sat, May 16, priced at $728 found 5 days ago
TAP Portugal
Sat, May 2 - Sat, May 16
OPO
Porto
TMS
São Tomé Island
$732 Roundtrip, found 5 days ago
$732
Roundtrip
found 5 days ago
Select TAP Portugal flight, departing Sat, May 2 from Porto to São Tomé Island, returning Sat, May 16, priced at $732 found 5 days ago
TAP Portugal
Sat, May 2 - Sat, May 16
OPO
Porto
TMS
São Tomé Island
$735 Roundtrip, found 5 days ago
$735
Roundtrip
found 5 days ago
Select TAP Portugal flight, departing Sat, May 2 from Porto to São Tomé Island, returning Sat, May 16, priced at $735 found 5 days ago
TAP Portugal
Sat, May 2 - Sat, May 16
OPO
Porto
TMS
São Tomé Island
$799 Roundtrip, found 5 days ago
$799
Roundtrip
found 5 days ago
Select TAP Portugal flight, departing Sat, May 2 from Porto to São Tomé Island, returning Sat, May 16, priced at $799 found 5 days ago
TAP Portugal
Sat, May 2 - Sat, May 16
OPO
Porto
TMS
São Tomé Island
$803 Roundtrip, found 5 days ago
$803
Roundtrip
found 5 days ago
Select TAP Portugal flight, departing Sat, May 2 from Porto to São Tomé Island, returning Sat, May 16, priced at $803 found 5 days ago
TAP Portugal
Sat, May 2 - Sat, May 16
OPO
Porto
TMS
São Tomé Island
$806 Roundtrip, found 5 days ago
$806
Roundtrip
found 5 days ago
Select TAP Portugal flight, departing Sat, May 2 from Porto to São Tomé Island, returning Sat, May 16, priced at $806 found 5 days ago
TAP Portugal
Sat, Nov 22 - Sat, Nov 29
OPO
Porto
TMS
São Tomé Island
$855 Roundtrip, found 2 days ago
$855
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Sat, Nov 22 from Porto to São Tomé Island, returning Sat, Nov 29, priced at $855 found 2 days ago
TAP Portugal
Sat, Nov 22 - Sat, Nov 29
OPO
Porto
TMS
São Tomé Island
$862 Roundtrip, found 2 days ago
$862
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Sat, Nov 22 from Porto to São Tomé Island, returning Sat, Nov 29, priced at $862 found 2 days ago
TAP Portugal
Sat, May 2 - Sat, May 16
OPO
Porto
TMS
São Tomé Island
$895 Roundtrip, found 5 days ago
$895
Roundtrip
found 5 days ago
Select TAP Portugal flight, departing Sat, May 2 from Porto to São Tomé Island, returning Sat, May 16, priced at $895 found 5 days ago
TAP Portugal
Sat, May 2 - Sat, May 16
OPO
Porto
TMS
São Tomé Island
$899 Roundtrip, found 5 days ago
$899
Roundtrip
found 5 days ago
Select TAP Portugal flight, departing Sat, May 2 from Porto to São Tomé Island, returning Sat, May 16, priced at $899 found 5 days ago

Frequently asked questions

How much does a flight from Dr. Francisco de Sa Carneiro Airport (OPO) to Sao Tome Intl. Airport (TMS) cost?
Secure a cheap one-way flight from $686 or cheap return flight from $728 from Dr. Francisco de Sa Carneiro Airport (OPO) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Dr. Francisco de Sa Carneiro Airport (OPO) to Sao Tome Intl. Airport (TMS)?
May is the cheapest month to fly from OPO to TMS. Planning your trip for the off-season is often the key to landing a great deal.
What is the cheapest airline that flies from Dr. Francisco de Sa Carneiro Airport (OPO) to Sao Tome Intl. Airport (TMS)?
To find the cheapest airline that'll fly you from OPO to TMS, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Dr. Francisco de Sa Carneiro Airport (OPO) to Sao Tome Intl. Airport (TMS)?
Direct flights from Dr. Francisco de Sa Carneiro Airport (OPO) to Sao Tome Intl. Airport (TMS) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from OPO to TMS?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Dr. Francisco de Sa Carneiro Airport (OPO) to Sao Tome Intl. Airport (TMS)?
Book a flight from Dr. Francisco de Sa Carneiro Airport (OPO) to Sao Tome Intl. Airport (TMS) that leaves before 3 PM to reduce the likelihood of delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Dr. Francisco de Sa Carneiro Airport (OPO) to Sao Tome Intl. Airport (TMS) last-minute?
Waiting until right before your break to book a flight from OPO to TMS often results in higher prices. While it's possible to find some last-minute deals, there's no guarantee. Keep your travel schedule open for the best chance of getting a bargain.
Is it cheaper to book an OPO to TMS flight and hotel package?
Compared with arranging hotels and flights separately, booking an OPO to TMS flight and hotel package with Expedia could result in significant savings. Better yet, having it all in one place will take the hassle out of planning your trip. Just secure your flights and select from our extensive range of stays, then personalize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Dr. Francisco de Sa Carneiro Airport (OPO) to Sao Tome Intl. Airport (TMS)?
Usually, it's possible to cancel or reschedule your OPO to TMS flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Dr. Francisco de Sa Carneiro
Destination airport
São Tomé Intl.
Roundtrip price
$727
Distance
2982 mi

Book with confidence

Porto to São Tomé Island Flights

The cheapest times to fly from Porto to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Porto to São Tomé Island are during the month of May. You can find some of the cheapest flights from Porto to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Porto to São Tomé Island

Sunday is one of the best days to book for cheap flights from Porto to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Porto to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Porto to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $686 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Porto to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Porto to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Porto to São Tomé Island Flights
*Available to One Key members.