$222 Cheap Flights from Portland (PDX) to Santiago (STI)

View $222 flight on Fri, Jan 23, 2026Opens in a new window

Popular airlines from Portland International Airport (PDX) to Cibao Intl. Airport (STI)

Cheap Flights from Portland to Santiago (PDX-STI)

Prices were available within the past 7 days and start at $222 for one-way flights and $468 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Jan 23 - Fri, Feb 13
PDX
Portland
STI
Santiago de los Caballeros
$468 Roundtrip, found 5 hours ago
$468
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, Jan 23 from Portland to Santiago de los Caballeros, returning Fri, Feb 13, priced at $468 found 5 hours ago
Delta
Fri, Jan 23 - Fri, Feb 13
PDX
Portland
STI
Santiago de los Caballeros
$468 Roundtrip, found 5 hours ago
$468
Roundtrip
found 5 hours ago
Select Delta flight, departing Fri, Jan 23 from Portland to Santiago de los Caballeros, returning Fri, Feb 13, priced at $468 found 5 hours ago
American Airlines
Tue, Jan 6 - Tue, Jan 27
PDX
Portland
STI
Santiago de los Caballeros
$472 Roundtrip, found 10 hours ago
$472
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Tue, Jan 6 from Portland to Santiago de los Caballeros, returning Tue, Jan 27, priced at $472 found 10 hours ago
American Airlines
Fri, Dec 5 - Sun, Dec 14
PDX
Portland
STI
Santiago de los Caballeros
$477 Roundtrip, found 2 days ago
$477
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Dec 5 from Portland to Santiago de los Caballeros, returning Sun, Dec 14, priced at $477 found 2 days ago
American Airlines
Tue, Jan 6 - Tue, Jan 27
PDX
Portland
STI
Santiago de los Caballeros
$481 Roundtrip, found 10 hours ago
$481
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Tue, Jan 6 from Portland to Santiago de los Caballeros, returning Tue, Jan 27, priced at $481 found 10 hours ago
American Airlines
Fri, Dec 5 - Fri, Dec 12
PDX
Portland
STI
Santiago de los Caballeros
$484 Roundtrip, found 1 day ago
$484
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Dec 5 from Portland to Santiago de los Caballeros, returning Fri, Dec 12, priced at $484 found 1 day ago
American Airlines
Fri, Dec 5 - Sun, Dec 14
PDX
Portland
STI
Santiago de los Caballeros
$485 Roundtrip, found 2 days ago
$485
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Dec 5 from Portland to Santiago de los Caballeros, returning Sun, Dec 14, priced at $485 found 2 days ago
American Airlines
Fri, Dec 5 - Fri, Dec 12
PDX
Portland
STI
Santiago de los Caballeros
$485 Roundtrip, found 1 day ago
$485
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Dec 5 from Portland to Santiago de los Caballeros, returning Fri, Dec 12, priced at $485 found 1 day ago
American Airlines
Thu, Dec 4 - Sun, Dec 14
PDX
Portland
STI
Santiago de los Caballeros
$486 Roundtrip, found 1 day ago
$486
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Dec 4 from Portland to Santiago de los Caballeros, returning Sun, Dec 14, priced at $486 found 1 day ago
United
Tue, Jan 6 - Tue, Jan 27
PDX
Portland
STI
Santiago de los Caballeros
$499 Roundtrip, found 10 hours ago
$499
Roundtrip
found 10 hours ago
Select United flight, departing Tue, Jan 6 from Portland to Santiago de los Caballeros, returning Tue, Jan 27, priced at $499 found 10 hours ago

Find the cheapest month to fly from Portland (PDX) to Santiago de los Caballeros (STI)

October is typically the cheapest month to fly

From $464 - $779 per traveler.

Alternative airports near Santiago de los Caballeros

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Gregorio Luperon Intl. POP. Cheapest option available. Average driving time to city center is 59 minutes. Flights from $603
POP
Gregorio Luperon Intl.
Cheapest
Average driving time to city center59 min
Flights from $603

Frequently asked questions

How much does a flight from Portland Intl. Airport (PDX) to Cibao Intl. Airport (STI) cost?
Get a cheap one-way flight from $222 or cheap return flight from $468 from Portland Intl. Airport (PDX) to Cibao Intl. Airport (STI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Portland Intl. Airport (PDX) to Cibao Intl. Airport (STI)?
Traveling in January is a good way to save, as it's the cheapest month for flights between PDX and STI. You'll typically find the lowest fares during the off-season.
What is the cheapest airline that flies from Portland Intl. Airport (PDX) to Cibao Intl. Airport (STI)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest PDX to STI flight.
How many flights per day from Portland Intl. Airport (PDX) to Cibao Intl. Airport (STI)?
You'll need to hop on a flight with a layover when traveling from Portland Intl. Airport (PDX) to Cibao Intl. Airport (STI). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from PDX to STI?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary based on a range of factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Portland Intl. Airport (PDX) to Cibao Intl. Airport (STI)?
To touch down at Cibao Intl. Airport (STI) on schedule, opt for a flight that leaves from Portland Intl. Airport (PDX) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Portland Intl. Airport (PDX) to Cibao Intl. Airport (STI) last-minute?
Waiting until right before your break to book your flight from PDX to STI generally means paying more. While you may find some last-minute offers, they aren't always guaranteed. Keep your travel schedule open to boost your chances of snagging a bargain.
Is it cheaper to book a PDX to STI flight and hotel package?
You can save money by booking a PDX to STI flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After choosing your preferred accommodations and flights, consider adding extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Portland Intl. Airport (PDX) to Cibao Intl. Airport (STI)?
In most instances, you can reschedule or cancel your PDX to STI flight. However, additional charges may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you need further information, go to our Customer Service portal.

Travel information

Origin airport
Portland Intl.
Destination airport
Cibao Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$467
Distance
3449 mi

Book with confidence

Portland to Santiago Flights

The cheapest times to fly from Portland to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Portland to Santiago are during the month of January. You can find some of the cheapest flights from Portland to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Portland to Santiago

Sunday is one of the best days to book for cheap flights from Portland to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Portland to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Portland to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $222 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Portland to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Portland to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Portland to Santiago Flights

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*Available to One Key members.