$317 Cheap Flights from Reynosa (REX) to Santo Domingo (SDQ)

View $317 flight on Thu, Jan 1, 2026Opens in a new window

Popular airlines from Reynosa, Tamaulipas (REX-General Lucio Blanco Intl.) to Las Americas Intl. Airport (SDQ)

Cheap Flights from Reynosa to Santo Domingo (REX-SDQ)

Prices were available within the past 7 days and start at $317 for one-way flights and $543 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Tue, Jan 6 - Wed, Jan 14
REX
Reynosa
SDQ
Santo Domingo
$543 Roundtrip, found 5 days ago
$543
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Tue, Jan 6 from Reynosa to Santo Domingo, returning Wed, Jan 14, priced at $543 found 5 days ago
Aeromexico
Tue, Jan 6 - Mon, Jan 12
REX
Reynosa
SDQ
Santo Domingo
$564 Roundtrip, found 5 days ago
$564
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Tue, Jan 6 from Reynosa to Santo Domingo, returning Mon, Jan 12, priced at $564 found 5 days ago
Aeromexico
Tue, Jan 6 - Sun, Jan 11
REX
Reynosa
SDQ
Santo Domingo
$580 Roundtrip, found 5 days ago
$580
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Tue, Jan 6 from Reynosa to Santo Domingo, returning Sun, Jan 11, priced at $580 found 5 days ago
Aeromexico
Tue, Jan 6 - Thu, Jan 15
REX
Reynosa
SDQ
Santo Domingo
$585 Roundtrip, found 5 days ago
$585
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Tue, Jan 6 from Reynosa to Santo Domingo, returning Thu, Jan 15, priced at $585 found 5 days ago
Aeromexico
Mon, Jan 5 - Mon, Jan 12
REX
Reynosa
SDQ
Santo Domingo
$595 Roundtrip, found 5 days ago
$595
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Mon, Jan 5 from Reynosa to Santo Domingo, returning Mon, Jan 12, priced at $595 found 5 days ago
Aeromexico
Thu, Jan 8 - Mon, Jan 12
REX
Reynosa
SDQ
Santo Domingo
$616 Roundtrip, found 5 days ago
$616
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Thu, Jan 8 from Reynosa to Santo Domingo, returning Mon, Jan 12, priced at $616 found 5 days ago
Aeromexico
Mon, Jan 5 - Mon, Jan 12
REX
Reynosa
SDQ
Santo Domingo
$628 Roundtrip, found 5 days ago
$628
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Mon, Jan 5 from Reynosa to Santo Domingo, returning Mon, Jan 12, priced at $628 found 5 days ago
Aeromexico
Thu, Jan 8 - Sun, Jan 11
REX
Reynosa
SDQ
Santo Domingo
$632 Roundtrip, found 5 days ago
$632
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Thu, Jan 8 from Reynosa to Santo Domingo, returning Sun, Jan 11, priced at $632 found 5 days ago
Aeromexico
Thu, Jan 8 - Thu, Jan 15
REX
Reynosa
SDQ
Santo Domingo
$637 Roundtrip, found 5 days ago
$637
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Thu, Jan 8 from Reynosa to Santo Domingo, returning Thu, Jan 15, priced at $637 found 5 days ago
Aeromexico
Sun, Jan 4 - Mon, Jan 12
REX
Reynosa
SDQ
Santo Domingo
$653 Roundtrip, found 5 days ago
$653
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Sun, Jan 4 from Reynosa to Santo Domingo, returning Mon, Jan 12, priced at $653 found 5 days ago

Frequently asked questions

How much does a flight from General Lucio Blanco Intl. Airport (REX) to Las Americas Intl. Airport (SDQ) cost?
Get a cheap one-way flight from $317 or cheap return flight from $543 from General Lucio Blanco Intl. Airport (REX) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from General Lucio Blanco Intl. Airport (REX) to Las Americas Intl. Airport (SDQ)?
Traveling in January is a great way to save, as it's the cheapest month for flights between REX and SDQ. You'll typically find the lowest fares during the off-season.
What is the cheapest airline that flies from General Lucio Blanco Intl. Airport (REX) to Las Americas Intl. Airport (SDQ)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest REX to SDQ flight.
How many flights per day from General Lucio Blanco Intl. Airport (REX) to Las Americas Intl. Airport (SDQ)?
You'll need to take a flight with a layover if you're traveling from General Lucio Blanco Intl. Airport (REX) to Las Americas Intl. Airport (SDQ). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from REX to SDQ?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from General Lucio Blanco Intl. Airport (REX) to Las Americas Intl. Airport (SDQ)?
To avoid possible delays on the General Lucio Blanco Intl. Airport (REX) to Las Americas Intl. Airport (SDQ) route, aim to fly before 3 PM. Later flights have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from General Lucio Blanco Intl. Airport (REX) to Las Americas Intl. Airport (SDQ) last-minute?
Waiting until just before your trip to book a flight from REX to SDQ often results in higher prices. Although you may find some last-minute offers, there's no guarantee. Be flexible with your itinerary for the best chance of getting a bargain.
Is it cheaper to book a REX to SDQ flight and hotel package?
You'll generally save money by booking a REX to SDQ flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've selected your ideal flights and accommodations, you can add extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from General Lucio Blanco Intl. Airport (REX) to Las Americas Intl. Airport (SDQ)?
In most cases, you can modify or cancel your REX to SDQ flight. However, additional fees may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you need more information, go to our Customer Service portal.

Travel information

Origin airport
General Lucio Blanco Intl.
Destination airport
Las Americas Intl.
Roundtrip price
$543
Distance
1895 mi

Book with confidence

Reynosa to Santo Domingo Flights

The cheapest times to fly from Reynosa to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Reynosa to Santo Domingo are during the month of January. You can find some of the cheapest flights from Reynosa to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Reynosa to Santo Domingo

Sunday is one of the best days to book for cheap flights from Reynosa to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Reynosa to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Reynosa to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $317 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Reynosa to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Reynosa to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Reynosa to Santo Domingo Flights

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*Available to One Key members.