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$61 Cheap Flights from Fort Myers (RSW) to Greenville (GSP)

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina

Cheap Flights from Fort Myers to Greenville (RSW-GSP)

Prices were available within the past 7 days and start at $61 for one-way flights and $122 for roundtrip, for the period specified. Prices and availability are subject to change.

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

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Fort Myers (RSW) to Greenville (GSP) at a glance

Travelers can choose from a range of airlines providing flights from Fort Myers (RSW) to Greenville (GSP) on this domestic short-haul route. Whether you're seeking cheap flights from Fort Myers or prefer nonstop options, compare full-service and budget airlines to discover the itinerary that aligns with your schedule and budget. Explore the iconic sights and neighborhoods of Greenville while gathering essential information for your journey from Southwest Florida International Airport to Greenville-Spartanburg International Airport.

  • Fastest flight duration: around 2 hours non-stop
  • Route distance: roughly 600 miles (970 km)
  • Flights per week: around 11 departures on average
  • Typical fares (one-way): economy tickets often range from $65–$410, depending on seasonality and how far ahead you book

Flights from Southwest Florida International Airport (RSW) to Greenville-Spartanburg International Airport (GSP)

According to recent traveler bookings, the top airlines flying from Fort Myers to Greenville are often selected for their one-stop and non-stop options. Common layover points include Charlotte-Douglas International Airport (CLT) with around a 1 hour and 15 minute layover, Hartsfield-Jackson Atlanta International Airport (ATL) offering a layover of approximately 1 hour, and Nashville International Airport (BNA) which features a 1 hour and 30 minute layover. These choices allow you to balance price, travel time, and cabin class to create the ideal itinerary for your journey.

  • American Airlines: This full-service airline provides one-stop options, with one-way ticket prices generally between $115 and $415. It accounts for about 43% of the departures on this route. Expect an in-flight duration of 3 hours and a total travel time of around 4 hours and 15 minutes, including layover.
  • Delta: Another full-service carrier, Delta offers one-stop services with one-way fares that usually range from $115 to $485. It represents approximately 33% of the flights on this route, featuring a flying time of 3 hours and a full journey time of roughly 4 hours and 15 minutes, considering the layover.
  • Breeze: As a low-cost option, Breeze provides non-stop flights with one-way fares typically spanning from $65 to $175. This airline covers around 18% of the departures for this route, ensuring a total travel time of just 2 hours.
  • Southwest Airlines: Known for its low-cost offerings, Southwest Airlines features one-stop services with one-way fares usually ranging from $130 to $435. It comprises about 4% of the departures on this route, with an in-flight duration of 3 hours and a total journey time of approximately 4 hours and 15 minutes, including layover.

Best time to fly from Fort Myers (RSW) to Greenville (GSP)

The most popular months for travelers flying from Fort Myers to Greenville are February, March, and April, when peak temperatures in Greenville reach up to 59.9°F in April. If you prefer quieter travel, consider July, the least busy time to visit with temperatures around 79.5°F and typically the lowest average one-way fare (around $135). Flight availability peaks in February, March, October, and November, with approximately 12 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 8 flights per week.

  • Cheapest time to fly: July usually offers good deals with average one-way fare around $135, roughly 29% cheaper than the yearly average.
  • Most flight options: February, March, October, and November have the highest number of flights from Fort Myers to Greenville, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
MonthTemperatureDemandWeekly FlightsAverage one-way Fare
January41.4°F (5.2°C)Average8$223
February45.3°F (7.4°C)Moderately High12$240
March51.8°F (11.0°C)Moderately High12$260
April59.9°F (15.5°C)Moderately High10$226
May68.4°F (20.2°C)Average11$167
June76.1°F (24.5°C)Average11$159
July79.5°F (26.4°C)Moderately Low11$135
August77.5°F (25.3°C)Average11$166
September72.3°F (22.4°C)Moderately Low9$174
October61.9°F (16.6°C)Average12$181
November51.1°F (10.6°C)Average12$184
December45.3°F (7.4°C)Moderately Low10$173

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Fort Myers (RSW) to Greenville (GSP)

  • Fort Myers to Greenville (FMY-GSP): Located approximately 8 miles from Southwest Florida International Airport (RSW), Page Field Airport (FMY) serves as a convenient alternative.
  • Fort Myers to Greenville (RSW-GMU): Greenville Downtown Airport (GMU) is roughly 8 miles from Greenville-Spartanburg International Airport (GSP), providing an accessible option for travelers.

How to find the best prices for flights from Fort Myers (RSW) to Greenville (GSP)

Getting some of the best deals on flights from Fort Myers to Greenville is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are generally available when booking at least two months in advance, although most travelers tend to book between two to eight weeks ahead. Departures in the morning, from 5 a.m. to 12 p.m., not only offer lower prices but are also the most popular flight times. Additionally, flying on Thursday provides both affordability and popularity among travelers.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Greenville hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Greenville-Spartanburg International Airport from Southwest Florida International Airport

Greenville welcomes travelers from Fort Myers with a range of transport options based on price, convenience, and proximity. Greenville city center is approximately a 20-minute drive (covering about 16 miles) from Greenville-Spartanburg International Airport, depending on traffic. Here's how to reach Greenville efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Greenville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Greenville-Spartanburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Greenville-Spartanburg International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Fort Myers to Greenville Flights

The cheapest times to fly from Fort Myers to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to Greenville are during the month of January. You can find some of the cheapest flights from Fort Myers to Greenville with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Fort Myers to Greenville

Sunday is one of the best days to book for cheap flights from Fort Myers to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Fort Myers to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $61 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently Asked Questions

How much does a flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) cost?

You can find cheap one-way flights from $61 and cheap return flights $122 Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) with Expedia. One-way flights typically cost between $156 and $888, and return flights often range between $305 and $1221. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) ticket fares go up or down.

*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.

What is the cheapest month to fly from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

July is typically the cheapest month to fly from Fort Myers, FL (RSW) to Greenville, SC (GSP), with average return fares around $292. This price is about 18% lower than the average throughout the year, as July often sees less demand for travel after the summer peak. Other cheap months to fly from RSW to GSP include August and September.

*Averages based on flights available on Expedia in the last year.

Which airlines fly direct from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

Enter RSW to GSP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.

How do I find cheap flights from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

To find a cheap flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.

What is the best airline to fly with from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

The best airline to fly with from Fort Myers, FL (RSW) to Greenville, SC (GSP) will differ from traveler to traveler. If you like to fly early, MX offers early morning flights. If price is the most important factor, MX typically offers the lowest fares. American Airlines offers the most daily flights from RSW to GSP, which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.

What is the best time to fly from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

The ideal time to fly from Fort Myers, FL (RSW) to Greenville, SC (GSP) is in July or September. These months have average prices around $292 for a return flight, making them budget-friendly options. While they may not be the most popular months, they still offer a good balance of price and availability.

*Prices based on flights available on Expedia in the last year.

How many flights per day from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

On average, there are around 1 nonstop flights per day from Southwest Florida Intl. (RSW) to Greenville-Spartanburg Intl. (GSP). For more options, look at flights that include layovers.

What is the earliest flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

The earliest flight from Fort Myers, FL (RSW) to Greenville, SC (GSP) generally departs at around 5:00 AM, operated by WN. This seasonal service is available in April and May, making it a great choice for early risers. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.

How long does it take to fly from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

Flying nonstop from RSW to GSP takes around 1 hour 50 minutes, with the route covering approximately 579 miles. Flights with a layover typically take 4 hours 30 minutes longer than direct options. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.

Can you fly business or first class from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

First class is available on flights from RSW to GSP. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight with Expedia?

It's easy to earn miles on a Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

What airports do you fly into for Greenville from Southwest Florida Intl. (RSW)?

From Southwest Florida Intl. (RSW), you can fly into Pitt-Greenville (PGV) and Greenville-Spartanburg Intl. (GSP) in Greenville. Compare routes and airports on Expedia to find the best flight options for your travel plans.

Is it cheaper to buy a plane ticket from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) at the last minute?

Typically, booking a last minute flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

Is it cheaper to book a Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package?

Securing a Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

Can I cancel or change the date of my flight from Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

If you booked your Fort Myers, FL (RSW-Southwest Florida Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Southwest Florida Intl. Airport
Destination airport
Greenville-Spartanburg Intl. Airport
Distance
578 miles away
Airlines serving
Breeze Airways, American Airlines, Delta, Southwest Airlines, United
Popular airline
Breeze Airways
Roundtrip price
$122
Average flight time
1 hour 47 mins
*Available to One Key members.