$253 Cheap Flights from Santo Domingo (SDQ) to Medellin (EOH)

View $253 flight on Tue, Nov 25, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Medellin (EOH-Enrique Olaya Herrera)

Cheap Flights from Santo Domingo to Medellin (SDQ-EOH)

Prices were available within the past 7 days and start at $253 for one-way flights and $531 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Tue, Nov 25 - Wed, Nov 26
SDQ
Santo Domingo
EOH
Medellin
$531 Roundtrip, just found
$531
Roundtrip
just found
Select avianca flight, departing Tue, Nov 25 from Santo Domingo to Medellin, returning Wed, Nov 26, priced at $531 just found
avianca
Tue, Nov 4 - Tue, Nov 11
SDQ
Santo Domingo
EOH
Medellin
$543 Roundtrip, just found
$543
Roundtrip
just found
Select avianca flight, departing Tue, Nov 4 from Santo Domingo to Medellin, returning Tue, Nov 11, priced at $543 just found
avianca
Sun, Nov 16 - Fri, Nov 21
SDQ
Santo Domingo
EOH
Medellin
$543 Roundtrip, found 1 day ago
$543
Roundtrip
found 1 day ago
Select avianca flight, departing Sun, Nov 16 from Santo Domingo to Medellin, returning Fri, Nov 21, priced at $543 found 1 day ago
avianca
Wed, Nov 26 - Mon, Dec 1
SDQ
Santo Domingo
EOH
Medellin
$555 Roundtrip, found 3 hours ago
$555
Roundtrip
found 3 hours ago
Select avianca flight, departing Wed, Nov 26 from Santo Domingo to Medellin, returning Mon, Dec 1, priced at $555 found 3 hours ago
avianca
Fri, Nov 14 - Mon, Nov 17
SDQ
Santo Domingo
EOH
Medellin
$565 Roundtrip, just found
$565
Roundtrip
just found
Select avianca flight, departing Fri, Nov 14 from Santo Domingo to Medellin, returning Mon, Nov 17, priced at $565 just found
avianca
Sat, Feb 14 - Thu, Feb 19
SDQ
Santo Domingo
EOH
Medellin
$577 Roundtrip, found 1 hour ago
$577
Roundtrip
found 1 hour ago
Select avianca flight, departing Sat, Feb 14 from Santo Domingo to Medellin, returning Thu, Feb 19, priced at $577 found 1 hour ago
avianca
Thu, Nov 20 - Sun, Nov 23
SDQ
Santo Domingo
EOH
Medellin
$600 Roundtrip, just found
$600
Roundtrip
just found
Select avianca flight, departing Thu, Nov 20 from Santo Domingo to Medellin, returning Sun, Nov 23, priced at $600 just found
avianca
Thu, Mar 19 - Mon, Mar 23
SDQ
Santo Domingo
EOH
Medellin
$608 Roundtrip, just found
$608
Roundtrip
just found
Select avianca flight, departing Thu, Mar 19 from Santo Domingo to Medellin, returning Mon, Mar 23, priced at $608 just found
avianca
Tue, Nov 4 - Tue, Nov 11
SDQ
Santo Domingo
EOH
Medellin
$620 Roundtrip, just found
$620
Roundtrip
just found
Select avianca flight, departing Tue, Nov 4 from Santo Domingo to Medellin, returning Tue, Nov 11, priced at $620 just found
avianca
Thu, Dec 18 - Tue, Dec 23
SDQ
Santo Domingo
EOH
Medellin
$642 Roundtrip, just found
$642
Roundtrip
just found
Select avianca flight, departing Thu, Dec 18 from Santo Domingo to Medellin, returning Tue, Dec 23, priced at $642 just found

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $231
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city center29 min
Flights from $231
Flights from Santo Domingo (SDQ) to Medellin (EOH)
Origin airport
Las Americas Intl.
Destination airport
Enrique Olaya Herrera
Airlines serving
avianca
Roundtrip price
$531
Distance
933 mi

Santo Domingo to Medellin Flights

The cheapest times to fly from Santo Domingo to Medellin

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Medellin are during the month of November. You can find some of the cheapest flights from Santo Domingo to Medellin with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Medellin

Sunday is one of the best days to book for cheap flights from Santo Domingo to Medellin: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Medellin

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Medellin in 2025. You can also book with separate airlines for your outbound and return journeys, from $253 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Medellin flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Medellin airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Enrique Olaya Herrera Airport (EOH) cost?
Lock in a cheap one-way flight from $253 or cheap return flight from $531 from Las Americas Intl. Airport (SDQ) to Enrique Olaya Herrera Airport (EOH) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to Enrique Olaya Herrera Airport (EOH)?
Traveling in November is a good way to save, as it's the cheapest month for flights between SDQ and EOH. You'll often find the lowest fares during the off-season.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to Enrique Olaya Herrera Airport (EOH)?
To find the cheapest airline flying from SDQ to EOH, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Las Americas Intl. Airport (SDQ) to Enrique Olaya Herrera Airport (EOH)?
Direct flights from Las Americas Intl. Airport (SDQ) to Enrique Olaya Herrera Airport (EOH) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SDQ to EOH?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Enrique Olaya Herrera Airport (EOH)?
Book a flight from Las Americas Intl. Airport (SDQ) to Enrique Olaya Herrera Airport (EOH) that takes off before 3 PM to reduce the risk of cancellations and delays. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Enrique Olaya Herrera Airport (EOH) last-minute?
Last-minute fares from SDQ to EOH are generally more expensive. To secure the cheapest rates, start searching for flights well in advance. That said, if you're flexible with your travel dates, you may land a cheap ticket right before your trip.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Enrique Olaya Herrera Airport (EOH)?
In most instances, you're able to cancel or reschedule your SDQ to EOH flight. However, additional charges may apply, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want more information, head to our Customer Service portal.

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*Available to One Key members.