$400 Cheap Flights from Santo Domingo (SDQ) to Prague (PRG)

View $400 flight on Wed, Dec 24, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG)

Cheap Flights from Santo Domingo to Prague (SDQ-PRG)

Prices were available within the past 7 days and start at $400 for one-way flights and $918 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Condor
Sun, Nov 16 - Mon, Nov 24
SDQ
Santo Domingo
PRG
Prague
$918 Roundtrip, found 2 days ago
$918
Roundtrip
found 2 days ago
Select Condor flight, departing Sun, Nov 16 from Santo Domingo to Prague, returning Mon, Nov 24, priced at $918 found 2 days ago
JetBlue Airways
Mon, Nov 17 - Mon, Nov 24
SDQ
Santo Domingo
PRG
Prague
$937 Roundtrip, found 2 days ago
$937
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Mon, Nov 17 from Santo Domingo to Prague, returning Mon, Nov 24, priced at $937 found 2 days ago
Condor
Sun, Nov 16 - Thu, Nov 27
SDQ
Santo Domingo
PRG
Prague
$968 Roundtrip, found 2 days ago
$968
Roundtrip
found 2 days ago
Select Condor flight, departing Sun, Nov 16 from Santo Domingo to Prague, returning Thu, Nov 27, priced at $968 found 2 days ago
JetBlue Airways
Thu, Nov 20 - Mon, Nov 24
SDQ
Santo Domingo
PRG
Prague
$986 Roundtrip, found 2 days ago
$986
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Thu, Nov 20 from Santo Domingo to Prague, returning Mon, Nov 24, priced at $986 found 2 days ago
Condor
Wed, Nov 19 - Mon, Nov 24
SDQ
Santo Domingo
PRG
Prague
$1,022 Roundtrip, found 2 days ago
$1,022
Roundtrip
found 2 days ago
Select Condor flight, departing Wed, Nov 19 from Santo Domingo to Prague, returning Mon, Nov 24, priced at $1,022 found 2 days ago
Condor
Wed, Nov 19 - Thu, Nov 27
SDQ
Santo Domingo
PRG
Prague
$1,071 Roundtrip, found 2 days ago
$1,071
Roundtrip
found 2 days ago
Select Condor flight, departing Wed, Nov 19 from Santo Domingo to Prague, returning Thu, Nov 27, priced at $1,071 found 2 days ago
United
Tue, Nov 18 - Mon, Nov 24
SDQ
Santo Domingo
PRG
Prague
$1,082 Roundtrip, found 2 days ago
$1,082
Roundtrip
found 2 days ago
Select United flight, departing Tue, Nov 18 from Santo Domingo to Prague, returning Mon, Nov 24, priced at $1,082 found 2 days ago
United
Wed, Nov 19 - Fri, Nov 28
SDQ
Santo Domingo
PRG
Prague
$1,095 Roundtrip, found 2 days ago
$1,095
Roundtrip
found 2 days ago
Select United flight, departing Wed, Nov 19 from Santo Domingo to Prague, returning Fri, Nov 28, priced at $1,095 found 2 days ago
Air Europa
Tue, Dec 30 - Fri, Jan 2
SDQ
Santo Domingo
PRG
Prague
$1,809 Roundtrip, found 5 days ago
$1,809
Roundtrip
found 5 days ago
Select Air Europa flight, departing Tue, Dec 30 from Santo Domingo to Prague, returning Fri, Jan 2, priced at $1,809 found 5 days ago
KLM
Fri, Dec 26 - Tue, Dec 30
SDQ
Santo Domingo
PRG
Prague
$1,841 Roundtrip, just found
$1,841
Roundtrip
just found
Select KLM flight, departing Fri, Dec 26 from Santo Domingo to Prague, returning Tue, Dec 30, priced at $1,841 just found

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG) cost?
Lock in a cheap one-way flight from $400 or cheap return flight from $918 from Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG)?
November is the most affordable month to fly from SDQ to PRG. Timing your trip outside of the busy season is often the key to finding a great deal.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll fly you from SDQ to PRG. Then, sort your results by "Price (lowest to highest)" to score a good deal.
How many flights per day from Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG)?
You'll have to hop on a flight with a layover if you're traveling from Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from SDQ to PRG?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can change based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG)?
To avoid potential delays on the Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG) route, travel before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG) last-minute?
Booking your plane ticket from SDQ to PRG shortly before your trip is usually more expensive. However, if you're flexible with your departure dates and times, you could grab a cheap last-minute fare.
Is it cheaper to book a SDQ to PRG flight and hotel package?
Opting for a SDQ to PRG flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Choose from our wide range of stays and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Vaclav Havel Airport (PRG)?
It's usually possible to reschedule or cancel your SDQ to PRG flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Las Americas Intl.
Destination airport
Vaclav Havel
Roundtrip price
$917
Distance
4983 mi

Book with confidence

Santo Domingo to Prague Flights

The cheapest times to fly from Santo Domingo to Prague

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Prague are during the month of November. You can find some of the cheapest flights from Santo Domingo to Prague with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Prague

Sunday is one of the best days to book for cheap flights from Santo Domingo to Prague: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Prague

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Prague in 2025. You can also book with separate airlines for your outbound and return journeys, from $400 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Prague flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Prague airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santo Domingo to Prague Flights

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*Available to One Key members.