$214 Cheap Flights from San Francisco (SFO) to Santo Domingo (SDQ)

View $214 flight on Tue, Oct 7, 2025Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)

Cheap Flights from San Francisco to Santo Domingo (SFO-SDQ)

Prices were available within the past 7 days and start at $214 for one-way flights and $392 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Mon, Oct 27 - Wed, Nov 12
SFO
San Francisco
SDQ
Santo Domingo
$392 Roundtrip, found 2 days ago
$392
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Mon, Oct 27 from San Francisco to Santo Domingo, returning Wed, Nov 12, priced at $392 found 2 days ago
JetBlue Airways
Mon, Nov 3 - Sat, Nov 8
SFO
San Francisco
SDQ
Santo Domingo
$393 Roundtrip, found 2 days ago
$393
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Mon, Nov 3 from San Francisco to Santo Domingo, returning Sat, Nov 8, priced at $393 found 2 days ago
JetBlue Airways
Sat, Oct 25 - Sat, Nov 1
SFO
San Francisco
SDQ
Santo Domingo
$402 Roundtrip, found 2 days ago
$402
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Sat, Oct 25 from San Francisco to Santo Domingo, returning Sat, Nov 1, priced at $402 found 2 days ago
JetBlue Airways
Wed, Oct 22 - Fri, Oct 31
SFO
San Francisco
SDQ
Santo Domingo
$411 Roundtrip, found 2 days ago
$411
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Wed, Oct 22 from San Francisco to Santo Domingo, returning Fri, Oct 31, priced at $411 found 2 days ago
JetBlue Airways
Sat, Oct 25 - Sat, Nov 1
SFO
San Francisco
SDQ
Santo Domingo
$412 Roundtrip, found 2 days ago
$412
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Sat, Oct 25 from San Francisco to Santo Domingo, returning Sat, Nov 1, priced at $412 found 2 days ago
JetBlue Airways
Sun, Oct 26 - Thu, Nov 6
SFO
San Francisco
SDQ
Santo Domingo
$422 Roundtrip, found 2 days ago
$422
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Sun, Oct 26 from San Francisco to Santo Domingo, returning Thu, Nov 6, priced at $422 found 2 days ago
Copa
Wed, Oct 29 - Thu, Oct 30
SFO
San Francisco
SDQ
Santo Domingo
$457 Roundtrip, found 2 days ago
$457
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Oct 29 from San Francisco to Santo Domingo, returning Thu, Oct 30, priced at $457 found 2 days ago
Frontier Airlines
Sat, Nov 8 - Sun, Nov 16
SFO
San Francisco
SDQ
Santo Domingo
$498 Roundtrip, found 2 days ago
$498
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Nov 8 from San Francisco to Santo Domingo, returning Sun, Nov 16, priced at $498 found 2 days ago
avianca
Tue, Oct 21 - Sat, Oct 25
SFO
San Francisco
SDQ
Santo Domingo
$547 Roundtrip, found 3 hours ago
$547
Roundtrip
found 3 hours ago
Select avianca flight, departing Tue, Oct 21 from San Francisco to Santo Domingo, returning Sat, Oct 25, priced at $547 found 3 hours ago
Aeromexico
Thu, Feb 26 - Thu, Mar 5
SFO
San Francisco
SDQ
Santo Domingo
$600 Roundtrip, found 13 hours ago
$600
Roundtrip
found 13 hours ago
Select Aeromexico flight, departing Thu, Feb 26 from San Francisco to Santo Domingo, returning Thu, Mar 5, priced at $600 found 13 hours ago

Find the cheapest month to fly from San Francisco (SFO) to Santo Domingo (SDQ)

October is typically the cheapest month to fly

From $411 - $869 per traveler.

Alternative airports near Santo Domingo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Las Americas Intl. SDQ. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $506
SDQ
Las Americas Intl.
Cheapest
Average driving time to city center22 min
Flights from $506
Flights from San Francisco (SFO) to Santo Domingo (SDQ)
Origin airport
San Francisco Intl.
Destination airport
Las Americas Intl.
Airlines serving
Aeromexico, American Airlines, Copa, Delta, Frontier Airlines, JetBlue Airways, United, avianca
Roundtrip price
$392
Distance
3426 mi

San Francisco to Santo Domingo Flights

The cheapest times to fly from San Francisco to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Francisco to Santo Domingo are during the month of October. You can find some of the cheapest flights from San Francisco to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Francisco to Santo Domingo

Sunday is one of the best days to book for cheap flights from San Francisco to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Francisco to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Francisco to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $214 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Francisco to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Francisco to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ) cost?
Snag a cheap one-way flight from $214 or cheap return flight from $392 from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)?
Planning your getaway for October can help you save, as it's the cheapest month for flights between SFO and SDQ. You'll often find the lowest fares during the off-season.
What is the cheapest airline that flies from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)?
To find the cheapest airline flying from SFO to SDQ, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)?
You'll have to hop on a flight with a layover when traveling from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from SFO to SDQ?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)?
To avoid possible delays on the San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ) route, travel before 3 PM. Flights after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ) last-minute?
Booking your flight from SFO to SDQ shortly before your getaway is generally more expensive. But if there's some wiggle room with your itinerary, you could land a cheap last-minute fare.
Is it cheaper to book a SFO to SDQ flight and hotel package?
Compared with arranging flights and hotels separately, booking a SFO to SDQ flight and hotel package with Expedia could result in significant savings. What's more, having everything in one convenient place will take the hassle out of planning your trip. Just secure your flights and choose from our wide range of stays, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)?
In most instances, you're able to reschedule or cancel your SFO to SDQ flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you need further details, go to our Customer Service portal.

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*Available to One Key members.