$212 Cheap Flights from San Francisco (SFO) to Santo Domingo (SDQ)

View $212 flight on Mon, Feb 2, 2026Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)

Cheap Flights from San Francisco to Santo Domingo (SFO-SDQ)

Prices were available within the past 7 days and start at $212 for one-way flights and $418 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Tue, Nov 18 - Wed, Nov 19
SFO
San Francisco
SDQ
Santo Domingo
$418 Roundtrip, found 2 days ago
$418
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Tue, Nov 18 from San Francisco to Santo Domingo, returning Wed, Nov 19, priced at $418 found 2 days ago
JetBlue Airways
Sun, Nov 16 - Mon, Nov 17
SFO
San Francisco
SDQ
Santo Domingo
$422 Roundtrip, found 2 days ago
$422
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Sun, Nov 16 from San Francisco to Santo Domingo, returning Mon, Nov 17, priced at $422 found 2 days ago
JetBlue Airways
Fri, Oct 31 - Thu, Nov 13
SFO
San Francisco
SDQ
Santo Domingo
$428 Roundtrip, found 3 days ago
$428
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Fri, Oct 31 from San Francisco to Santo Domingo, returning Thu, Nov 13, priced at $428 found 3 days ago
JetBlue Airways
Mon, Feb 16 - Tue, Feb 17
SFO
San Francisco
SDQ
Santo Domingo
$432 Roundtrip, found 2 days ago
$432
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Mon, Feb 16 from San Francisco to Santo Domingo, returning Tue, Feb 17, priced at $432 found 2 days ago
JetBlue Airways
Thu, Dec 4 - Fri, Dec 12
SFO
San Francisco
SDQ
Santo Domingo
$439 Roundtrip, found 3 days ago
$439
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Thu, Dec 4 from San Francisco to Santo Domingo, returning Fri, Dec 12, priced at $439 found 3 days ago
JetBlue Airways
Sun, Nov 9 - Thu, Nov 13
SFO
San Francisco
SDQ
Santo Domingo
$441 Roundtrip, found 3 days ago
$441
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Sun, Nov 9 from San Francisco to Santo Domingo, returning Thu, Nov 13, priced at $441 found 3 days ago
Copa
Thu, May 7 - Wed, May 13
SFO
San Francisco
SDQ
Santo Domingo
$460 Roundtrip, found 4 hours ago
$460
Roundtrip
found 4 hours ago
Select Copa flight, departing Thu, May 7 from San Francisco to Santo Domingo, returning Wed, May 13, priced at $460 found 4 hours ago
avianca
Wed, May 20 - Mon, May 25
SFO
San Francisco
SDQ
Santo Domingo
$550 Roundtrip, found 1 day ago
$550
Roundtrip
found 1 day ago
Select avianca flight, departing Wed, May 20 from San Francisco to Santo Domingo, returning Mon, May 25, priced at $550 found 1 day ago
Aeromexico
Sat, Feb 7 - Sat, Feb 14
SFO
San Francisco
SDQ
Santo Domingo
$602 Roundtrip, found 2 hours ago
$602
Roundtrip
found 2 hours ago
Select Aeromexico flight, departing Sat, Feb 7 from San Francisco to Santo Domingo, returning Sat, Feb 14, priced at $602 found 2 hours ago
American Airlines
Fri, Nov 28 - Thu, Dec 4
SFO
San Francisco
SDQ
Santo Domingo
$618 Roundtrip, just found
$618
Roundtrip
just found
Select American Airlines flight, departing Fri, Nov 28 from San Francisco to Santo Domingo, returning Thu, Dec 4, priced at $618 just found

Find the cheapest month to fly from San Francisco (SFO) to Santo Domingo (SDQ)

October is typically the cheapest month to fly

From $411 - $922 per traveler.

Alternative airports near Santo Domingo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Las Americas Intl. SDQ. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $513
SDQ
Las Americas Intl.
Cheapest
Average driving time to city center22 min
Flights from $513

Frequently asked questions

How much does a flight from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ) cost?
Snag a cheap one-way flight from $212 or cheap return flight from $418 from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)?
Planning your getaway for November can help you save, as it's the cheapest month for flights between SFO and SDQ. You'll often find the lowest fares during the off-season.
What is the cheapest airline that flies from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)?
To find the cheapest airline flying from SFO to SDQ, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)?
You'll have to hop on a flight with a layover when traveling from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from SFO to SDQ?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)?
To avoid possible delays on the San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ) route, travel before 3 PM. Flights after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ) last-minute?
Booking your flight from SFO to SDQ shortly before your getaway is generally more expensive. But if there's some wiggle room with your itinerary, you could land a cheap last-minute fare.
Is it cheaper to book a SFO to SDQ flight and hotel package?
Compared with arranging flights and hotels separately, booking a SFO to SDQ flight and hotel package with Expedia could result in significant savings. What's more, having everything in one convenient place will take the hassle out of planning your trip. Just secure your flights and choose from our wide range of stays, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from San Francisco Intl. Airport (SFO) to Las Americas Intl. Airport (SDQ)?
In most instances, you're able to reschedule or cancel your SFO to SDQ flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you need further details, go to our Customer Service portal.

Travel information

Origin airport
San Francisco Intl.
Destination airport
Las Americas Intl.
Airlines serving
Aeromexico, American Airlines, Copa, Delta, JetBlue Airways, United, avianca
Roundtrip price
$417
Distance
3426 mi

Book with confidence

San Francisco to Santo Domingo Flights

The cheapest times to fly from San Francisco to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Francisco to Santo Domingo are during the month of November. You can find some of the cheapest flights from San Francisco to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Francisco to Santo Domingo

Sunday is one of the best days to book for cheap flights from San Francisco to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Francisco to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Francisco to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $212 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Francisco to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Francisco to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

San Francisco to Santo Domingo Flights

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*Available to One Key members.