$139 Cheap Flights from St. Louis (STL) to Greenville (GSP)

View $139 flight on Tue, Oct 7, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)

Cheap Flights from St. Louis to Greenville (STL-GSP)

Prices were available within the past 7 days and start at $139 for one-way flights and $174 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Wed, Oct 29 - Wed, Nov 5
STL
St. Louis
GSP
Greenville
$174 Roundtrip, found 4 days ago
$174
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Wed, Oct 29 from St. Louis to Greenville, returning Wed, Nov 5, priced at $174 found 4 days ago
United
Wed, Oct 29 - Wed, Nov 5
STL
St. Louis
GSP
Greenville
$194 Roundtrip, found 4 days ago
$194
Roundtrip
found 4 days ago
Select United flight, departing Wed, Oct 29 from St. Louis to Greenville, returning Wed, Nov 5, priced at $194 found 4 days ago
Southwest Airlines
Wed, Oct 1 - Wed, Oct 8
STL
St. Louis
GSP
Greenville
$196 Roundtrip, found 6 days ago
$196
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Wed, Oct 1 from St. Louis to Greenville, returning Wed, Oct 8, priced at $196 found 6 days ago
Delta
Wed, Oct 29 - Wed, Nov 5
STL
St. Louis
GSP
Greenville
$198 Roundtrip, found 4 days ago
$198
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Oct 29 from St. Louis to Greenville, returning Wed, Nov 5, priced at $198 found 4 days ago
Southwest Airlines
Wed, Oct 1 - Tue, Oct 7
STL
St. Louis
GSP
Greenville
$199 Roundtrip, found 5 days ago
$199
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Oct 1 from St. Louis to Greenville, returning Tue, Oct 7, priced at $199 found 5 days ago
American Airlines
Sat, Oct 11 - Wed, Oct 15
STL
St. Louis
GSP
Greenville
$202 Roundtrip, found 4 days ago
$202
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 11 from St. Louis to Greenville, returning Wed, Oct 15, priced at $202 found 4 days ago
Southwest Airlines
Wed, Oct 1 - Tue, Oct 7
STL
St. Louis
GSP
Greenville
$205 Roundtrip, found 5 days ago
$205
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Oct 1 from St. Louis to Greenville, returning Tue, Oct 7, priced at $205 found 5 days ago
Delta
Sat, Oct 11 - Wed, Oct 15
STL
St. Louis
GSP
Greenville
$206 Roundtrip, found 4 days ago
$206
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Oct 11 from St. Louis to Greenville, returning Wed, Oct 15, priced at $206 found 4 days ago
Southwest Airlines
Wed, Oct 29 - Wed, Nov 5
STL
St. Louis
GSP
Greenville
$209 Roundtrip, found 4 days ago
$209
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Wed, Oct 29 from St. Louis to Greenville, returning Wed, Nov 5, priced at $209 found 4 days ago
American Airlines
Wed, Oct 29 - Sat, Nov 1
STL
St. Louis
GSP
Greenville
$210 Roundtrip, found 4 days ago
$210
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Oct 29 from St. Louis to Greenville, returning Sat, Nov 1, priced at $210 found 4 days ago

Find the cheapest month to fly from St. Louis (STL) to Greenville (GSP)

August is typically the cheapest month to fly

From $191 - $526 per traveler.
Flights from St. Louis (STL) to Greenville (GSP)
Origin airport
Lambert-St. Louis Intl.
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$173
Distance
523 mi

St. Louis to Greenville Flights

The cheapest times to fly from St. Louis to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Greenville are during the month of October. You can find some of the cheapest flights from St. Louis to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Greenville

Sunday is one of the best days to book for cheap flights from St. Louis to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $139 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Lock in a cheap one-way flight from $139 or cheap return flight from $174 from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)?
October is the cheapest month to fly from STL to GSP. Planning your trip for the off-season is often the key to finding a great deal.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll take you from STL to GSP. Then, sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)?
Nonstop flights from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from STL to GSP?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)?
To avoid potential delays on the Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP) route, aim to travel before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Booking your plane ticket from STL to GSP right before your getaway is typically more expensive. However, if there's some wiggle room with your travel times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a STL to GSP flight and hotel package?
You'll generally save money by securing a STL to GSP flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After selecting your ideal flights and accommodations, you can add extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Greenville-Spartanburg Intl. Airport (GSP)?
In most cases, you can reschedule or cancel your STL to GSP flight. However, there may be additional fees, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want further details, head to our Customer Service portal.

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*Available to One Key members.