$149 Cheap Flights from Syracuse (SYR) to Santo Domingo (SDQ)

View $149 flight on Thu, Oct 2, 2025Opens in a new window

Popular airlines from Hancock Intl. Airport (SYR) to Las Americas Intl. Airport (SDQ)

Cheap Flights from Syracuse to Santo Domingo (SYR-SDQ)

Prices were available within the past 7 days and start at $149 for one-way flights and $325 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Oct 2 - Mon, Oct 6
SYR
Syracuse
SDQ
Santo Domingo
$325 Roundtrip, found 1 day ago
$325
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Oct 2 from Syracuse to Santo Domingo, returning Mon, Oct 6, priced at $325 found 1 day ago
American Airlines
Thu, Oct 2 - Mon, Oct 6
SYR
Syracuse
SDQ
Santo Domingo
$325 Roundtrip, found 1 day ago
$325
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Oct 2 from Syracuse to Santo Domingo, returning Mon, Oct 6, priced at $325 found 1 day ago
Delta
Thu, Oct 2 - Mon, Oct 6
SYR
Syracuse
SDQ
Santo Domingo
$329 Roundtrip, found 1 day ago
$329
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Oct 2 from Syracuse to Santo Domingo, returning Mon, Oct 6, priced at $329 found 1 day ago
Delta
Wed, Oct 29 - Tue, Dec 2
SYR
Syracuse
SDQ
Santo Domingo
$333 Roundtrip, found 1 day ago
$333
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Oct 29 from Syracuse to Santo Domingo, returning Tue, Dec 2, priced at $333 found 1 day ago
Delta
Tue, Nov 18 - Tue, Dec 9
SYR
Syracuse
SDQ
Santo Domingo
$334 Roundtrip, found 10 hours ago
$334
Roundtrip
found 10 hours ago
Select Delta flight, departing Tue, Nov 18 from Syracuse to Santo Domingo, returning Tue, Dec 9, priced at $334 found 10 hours ago
American Airlines
Tue, Nov 18 - Tue, Dec 9
SYR
Syracuse
SDQ
Santo Domingo
$337 Roundtrip, found 10 hours ago
$337
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Tue, Nov 18 from Syracuse to Santo Domingo, returning Tue, Dec 9, priced at $337 found 10 hours ago
American Airlines
Thu, Oct 2 - Mon, Oct 6
SYR
Syracuse
SDQ
Santo Domingo
$337 Roundtrip, found 1 day ago
$337
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Oct 2 from Syracuse to Santo Domingo, returning Mon, Oct 6, priced at $337 found 1 day ago
JetBlue Airways
Sat, Oct 4 - Sun, Oct 5
SYR
Syracuse
SDQ
Santo Domingo
$369 Roundtrip, found 4 days ago
$369
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Sat, Oct 4 from Syracuse to Santo Domingo, returning Sun, Oct 5, priced at $369 found 4 days ago
United
Fri, Oct 17 - Fri, Oct 31
SYR
Syracuse
SDQ
Santo Domingo
$389 Roundtrip, found 3 days ago
$389
Roundtrip
found 3 days ago
Select United flight, departing Fri, Oct 17 from Syracuse to Santo Domingo, returning Fri, Oct 31, priced at $389 found 3 days ago
Frontier Airlines
Fri, Jan 9 - Sun, Jan 25
SYR
Syracuse
SDQ
Santo Domingo
$475 Roundtrip, found 17 hours ago
$475
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Fri, Jan 9 from Syracuse to Santo Domingo, returning Sun, Jan 25, priced at $475 found 17 hours ago

Find the cheapest month to fly from Syracuse (SYR) to Santo Domingo (SDQ)

February is typically the cheapest month to fly

From $350 - $678 per traveler.

Frequently asked questions

How much does a flight from Hancock Intl. Airport (SYR) to Las Americas Intl. Airport (SDQ) cost?
Snag a cheap one-way flight from $149 or cheap return flight from $325 from Hancock Intl. Airport (SYR) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Hancock Intl. Airport (SYR) to Las Americas Intl. Airport (SDQ)?
October is the cheapest month to fly from SYR to SDQ. Timing your trip outside of the busy season is often the key to finding better deals on flights.
What is the cheapest airline that flies from Hancock Intl. Airport (SYR) to Las Americas Intl. Airport (SDQ)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest SYR to SDQ flight.
How many flights per day from Hancock Intl. Airport (SYR) to Las Americas Intl. Airport (SDQ)?
There are no daily direct flights departing from Hancock Intl. Airport (SYR) to Las Americas Intl. Airport (SDQ). But you can book flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from SYR to SDQ?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a range of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Hancock Intl. Airport (SYR) to Las Americas Intl. Airport (SDQ)?
To touch down at Las Americas Intl. Airport (SDQ) on time, select a flight that takes off from Hancock Intl. Airport (SYR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Hancock Intl. Airport (SYR) to Las Americas Intl. Airport (SDQ) last-minute?
Booking your flight from SYR to SDQ right before your trip is typically more expensive. But if there's some wiggle room with your departure dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a SYR to SDQ flight and hotel package?
Compared with arranging hotels and flights separately, booking a SYR to SDQ flight and hotel package with Expedia could result in significant savings. Better still, managing everything in one place will take the stress out of planning your trip. Just pick your flights and select from our wide range of hotels, then tailor your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from Hancock Intl. Airport (SYR) to Las Americas Intl. Airport (SDQ)?
Usually, it's possible to reschedule or cancel your SYR to SDQ flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Travel information

Origin airport
Hancock Intl.
Destination airport
Las Americas Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, JetBlue Airways, United
Roundtrip price
$324
Distance
1746 mi

Book with confidence

Book with confidence

Syracuse to Santo Domingo Flights

The cheapest times to fly from Syracuse to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Syracuse to Santo Domingo are during the month of October. You can find some of the cheapest flights from Syracuse to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Syracuse to Santo Domingo

Sunday is one of the best days to book for cheap flights from Syracuse to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Syracuse to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Syracuse to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $149 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Syracuse to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Syracuse to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Syracuse to Santo Domingo Flights

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Explore a world of travel with Expedia

*Available to One Key members.