$553 Cheap Flights from Tampa (TPA) to Santander (SDR)

View $553 flight on Fri, Sep 26, 2025Opens in a new window

Popular airlines from Tampa Intl. Airport (TPA) to Santander (SDR)

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Cheap Flights from Tampa to Santander (TPA-SDR)

Prices were available within the past 7 days and start at $553 for one-way flights and $931 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Tue, Sep 16 - Tue, Sep 23
TPA
Tampa
SDR
Santander
$931 Roundtrip, found 16 hours ago
$931
Roundtrip
found 16 hours ago
Select Iberia flight, departing Tue, Sep 16 from Tampa to Santander, returning Tue, Sep 23, priced at $931 found 16 hours ago
Iberia
Sun, Sep 14 - Sat, Sep 20
TPA
Tampa
SDR
Santander
$958 Roundtrip, found 16 hours ago
$958
Roundtrip
found 16 hours ago
Select Iberia flight, departing Sun, Sep 14 from Tampa to Santander, returning Sat, Sep 20, priced at $958 found 16 hours ago
Iberia
Tue, Sep 16 - Mon, Sep 22
TPA
Tampa
SDR
Santander
$961 Roundtrip, found 16 hours ago
$961
Roundtrip
found 16 hours ago
Select Iberia flight, departing Tue, Sep 16 from Tampa to Santander, returning Mon, Sep 22, priced at $961 found 16 hours ago
Iberia
Mon, Sep 15 - Tue, Sep 23
TPA
Tampa
SDR
Santander
$969 Roundtrip, found 16 hours ago
$969
Roundtrip
found 16 hours ago
Select Iberia flight, departing Mon, Sep 15 from Tampa to Santander, returning Tue, Sep 23, priced at $969 found 16 hours ago
American Airlines
Fri, Sep 12 - Fri, Sep 19
TPA
Tampa
SDR
Santander
$982 Roundtrip, found 16 hours ago
$982
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Fri, Sep 12 from Tampa to Santander, returning Fri, Sep 19, priced at $982 found 16 hours ago
Iberia
Thu, Sep 11 - Fri, Sep 19
TPA
Tampa
SDR
Santander
$991 Roundtrip, found 16 hours ago
$991
Roundtrip
found 16 hours ago
Select Iberia flight, departing Thu, Sep 11 from Tampa to Santander, returning Fri, Sep 19, priced at $991 found 16 hours ago
Iberia
Sun, Sep 14 - Sat, Sep 20
TPA
Tampa
SDR
Santander
$996 Roundtrip, found 16 hours ago
$996
Roundtrip
found 16 hours ago
Select Iberia flight, departing Sun, Sep 14 from Tampa to Santander, returning Sat, Sep 20, priced at $996 found 16 hours ago
American Airlines
Sat, Sep 13 - Tue, Sep 23
TPA
Tampa
SDR
Santander
$996 Roundtrip, found 16 hours ago
$996
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Sat, Sep 13 from Tampa to Santander, returning Tue, Sep 23, priced at $996 found 16 hours ago
Iberia
Mon, Sep 15 - Mon, Sep 22
TPA
Tampa
SDR
Santander
$999 Roundtrip, found 16 hours ago
$999
Roundtrip
found 16 hours ago
Select Iberia flight, departing Mon, Sep 15 from Tampa to Santander, returning Mon, Sep 22, priced at $999 found 16 hours ago
Iberia
Sun, Sep 14 - Sat, Sep 20
TPA
Tampa
SDR
Santander
$1,005 Roundtrip, found 16 hours ago
$1,005
Roundtrip
found 16 hours ago
Select Iberia flight, departing Sun, Sep 14 from Tampa to Santander, returning Sat, Sep 20, priced at $1,005 found 16 hours ago
Flights from Tampa (TPA) to Santander (SDR)
Origin airport
Tampa Intl.
Destination airport
Santander
Roundtrip price
$931
Distance
4379 mi

Tampa to Santander Flights

The cheapest times to fly from Tampa to Santander

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tampa to Santander are during the month of September. You can find some of the cheapest flights from Tampa to Santander with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tampa to Santander

Sunday is one of the best days to book for cheap flights from Tampa to Santander: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tampa to Santander

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tampa to Santander in 2025. You can also book with separate airlines for your outbound and return journeys, from $553 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tampa to Santander flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tampa to Santander airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tampa Intl. Airport (TPA) to Santander Airport (SDR) cost?
Lock in a cheap one-way flight from $553 or cheap return flight from $931 from Tampa Intl. Airport (TPA) to Santander Airport (SDR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Tampa Intl. Airport (TPA) to Santander Airport (SDR)?
September is the cheapest month to fly from TPA to SDR. Traveling during an off-peak travel window is often the key to scoring lower fares.
What is the cheapest airline that flies from Tampa Intl. Airport (TPA) to Santander Airport (SDR)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest TPA to SDR flight.
How many flights per day from Tampa Intl. Airport (TPA) to Santander Airport (SDR)?
There aren't any daily nonstop flights available from Tampa Intl. Airport (TPA) to Santander Airport (SDR). But you can choose flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from TPA to SDR?
Usually you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* But this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tampa Intl. Airport (TPA) to Santander Airport (SDR)?
To avoid possible delays on the Tampa Intl. Airport (TPA) to Santander Airport (SDR) route, travel before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tampa Intl. Airport (TPA) to Santander Airport (SDR) last-minute?
Holding off until right before your break to book a ticket from TPA to SDR often results in higher prices. While you may come across some last-minute offers, they aren't always guaranteed. Allow some flexibility in your schedule for a better chance of landing a bargain.
Is it cheaper to book a TPA to SDR flight and hotel package?
You can save money by booking a TPA to SDR flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. Once you've chosen your preferred flights and accommodations, you can add extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from Tampa Intl. Airport (TPA) to Santander Airport (SDR)?
In most instances, you can cancel or modify your TPA to SDR flight. However, there may be additional fees, especially if you made your booking over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you need further details, head to our Customer Service portal.

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*Available to One Key members.