$173 Cheap Flights from Tupelo (TUP) to Columbus (CMH)

View $173 flight on Tue, Mar 3, 2026Opens in a new window

Popular airlines from Tupelo, MS (TUP-Tupelo Regional) to John Glenn Columbus Intl. Airport (CMH)

Cheap Flights from Tupelo to Columbus (TUP-CMH)

Prices were available within the past 7 days and start at $173 for one-way flights and $322 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Contour Airlines
Wed, Mar 25 - Thu, Apr 2
TUP
Tupelo
CMH
Columbus
$322 Roundtrip, found 15 hours ago
$322
Roundtrip
found 15 hours ago
Select Contour Airlines flight, departing Wed, Mar 25 from Tupelo to Columbus, returning Thu, Apr 2, priced at $322 found 15 hours ago
Contour Airlines
Tue, Mar 31 - Wed, Apr 1
TUP
Tupelo
CMH
Columbus
$325 Roundtrip, found 22 hours ago
$325
Roundtrip
found 22 hours ago
Select Contour Airlines flight, departing Tue, Mar 31 from Tupelo to Columbus, returning Wed, Apr 1, priced at $325 found 22 hours ago
Contour Airlines
Tue, Mar 3 - Tue, Mar 10
TUP
Tupelo
CMH
Columbus
$326 Roundtrip, found 18 hours ago
$326
Roundtrip
found 18 hours ago
Select Contour Airlines flight, departing Tue, Mar 3 from Tupelo to Columbus, returning Tue, Mar 10, priced at $326 found 18 hours ago
Contour Airlines
Tue, Mar 31 - Fri, Apr 3
TUP
Tupelo
CMH
Columbus
$333 Roundtrip, found 22 hours ago
$333
Roundtrip
found 22 hours ago
Select Contour Airlines flight, departing Tue, Mar 31 from Tupelo to Columbus, returning Fri, Apr 3, priced at $333 found 22 hours ago
Contour Airlines
Tue, Mar 3 - Tue, Mar 10
TUP
Tupelo
CMH
Columbus
$335 Roundtrip, found 2 days ago
$335
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Tue, Mar 3 from Tupelo to Columbus, returning Tue, Mar 10, priced at $335 found 2 days ago
Contour Airlines
Tue, Mar 3 - Tue, Mar 10
TUP
Tupelo
CMH
Columbus
$337 Roundtrip, found 18 hours ago
$337
Roundtrip
found 18 hours ago
Select Contour Airlines flight, departing Tue, Mar 3 from Tupelo to Columbus, returning Tue, Mar 10, priced at $337 found 18 hours ago
Contour Airlines
Tue, Mar 3 - Tue, Mar 10
TUP
Tupelo
CMH
Columbus
$342 Roundtrip, found 18 hours ago
$342
Roundtrip
found 18 hours ago
Select Contour Airlines flight, departing Tue, Mar 3 from Tupelo to Columbus, returning Tue, Mar 10, priced at $342 found 18 hours ago
Contour Airlines
Tue, Mar 3 - Sat, Mar 7
TUP
Tupelo
CMH
Columbus
$349 Roundtrip, found 18 hours ago
$349
Roundtrip
found 18 hours ago
Select Contour Airlines flight, departing Tue, Mar 3 from Tupelo to Columbus, returning Sat, Mar 7, priced at $349 found 18 hours ago
Contour Airlines
Mon, Mar 30 - Tue, Mar 31
TUP
Tupelo
CMH
Columbus
$359 Roundtrip, found 22 hours ago
$359
Roundtrip
found 22 hours ago
Select Contour Airlines flight, departing Mon, Mar 30 from Tupelo to Columbus, returning Tue, Mar 31, priced at $359 found 22 hours ago
Contour Airlines
Tue, Mar 3 - Tue, Mar 10
TUP
Tupelo
CMH
Columbus
$362 Roundtrip, found 18 hours ago
$362
Roundtrip
found 18 hours ago
Select Contour Airlines flight, departing Tue, Mar 3 from Tupelo to Columbus, returning Tue, Mar 10, priced at $362 found 18 hours ago

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Alternative airports near Columbus

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to John Glenn Columbus Intl. CMH. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $337
CMH
John Glenn Columbus Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $337

Frequently asked questions

How much does a flight from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) cost?
You can find cheap one-way flights from $173 and cheap return flights from $322 Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) with Expedia. One-way flights typically cost between $542 and $571. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
The cheapest month to fly from TUP to CMH is March when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
Enter TUP to CMH and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
Contour Airlines is the carrier that flies from Tupelo, MS (TUP) to Columbus, OH (CMH). Use Expedia's flight search tool to compare airlines on this route and find our cheapest option for your trip. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
To find a cheap flight from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
The earliest flight from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) typically departs at 7:45 AM, operated by Contour Airlines and American Airlines. This seasonal service is active in June, allowing you to start your day early and make the most of your time in Columbus. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
a Monday typically has the most flights from Tupelo Regional (TUP) to John Glenn Columbus Intl. (CMH), with approximately 2 flights available. This gives you plenty of options for your travel plans. A major airline on this route is Contour Airlines.
What are the most popular departure times for flights from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
The most popular departure times for flights from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) are typically between 6am and 9am. About 87% of passengers prefer this time window. Airlines like American Airlines and United Airlines frequently operate flights during this period. This timing is favored as it allows for a full day in Columbus upon arrival.
How long does it take to fly from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
A flight from TUP to CMH with a layover takes around 7 hours 50 minutes, with the route covering approximately 511 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
Select the "Business class" and "First class" filters when looking for TUP to CMH flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight with Expedia?
It's easy to earn miles on a Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Columbus from Tupelo Regional (TUP)?
If you're planning to travel to Columbus from Tupelo Regional (TUP), you can fly into John Glenn Columbus Intl. (CMH) Some flights may connect through major hubs like Nashville Intl. (BNA), Dallas-Fort Worth Intl. (DFW) before reaching Columbus. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) at the last minute?
Typically, booking a last minute flight from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight and hotel package?
Securing a Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) Columbus Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.)?
If you booked your Tupelo, MS (TUP-Tupelo Regional) to Columbus, OH (CMH-John Glenn Columbus Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tupelo Regional
Destination airport
John Glenn Columbus Intl.
Roundtrip price
$322
Distance
511 mi

Book with confidence

Tupelo to Columbus Flights

The cheapest times to fly from Tupelo to Columbus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tupelo to Columbus are during the month of March. You can find some of the cheapest flights from Tupelo to Columbus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tupelo to Columbus

Sunday is one of the best days to book for cheap flights from Tupelo to Columbus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tupelo to Columbus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tupelo to Columbus in 2026. You can also book with separate airlines for your outbound and return journeys, from $173 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tupelo to Columbus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tupelo to Columbus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Tupelo to Columbus Flights

*Flight schedules are subject to change.

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*Available to One Key members.