$405 Cheap Flights from Knoxville (TYS) to Prague (PRG)

View $405 flight on Mon, Dec 1, 2025Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG)

Cheap Flights from Knoxville to Prague (TYS-PRG)

Prices were available within the past 7 days and start at $405 for one-way flights and $505 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Mon, Dec 1 - Sun, Dec 7
TYS
Knoxville
PRG
Prague
$505 Roundtrip, found 18 hours ago
$505
Roundtrip
found 18 hours ago
Select Lufthansa flight, departing Mon, Dec 1 from Knoxville to Prague, returning Sun, Dec 7, priced at $505 found 18 hours ago
United
Sat, Jan 24 - Sat, Jan 31
TYS
Knoxville
PRG
Prague
$506 Roundtrip, found 13 hours ago
$506
Roundtrip
found 13 hours ago
Select United flight, departing Sat, Jan 24 from Knoxville to Prague, returning Sat, Jan 31, priced at $506 found 13 hours ago
Delta
Sat, Jan 24 - Sat, Jan 31
TYS
Knoxville
PRG
Prague
$507 Roundtrip, found 13 hours ago
$507
Roundtrip
found 13 hours ago
Select Delta flight, departing Sat, Jan 24 from Knoxville to Prague, returning Sat, Jan 31, priced at $507 found 13 hours ago
United
Sat, Jan 24 - Sat, Jan 31
TYS
Knoxville
PRG
Prague
$507 Roundtrip, found 13 hours ago
$507
Roundtrip
found 13 hours ago
Select United flight, departing Sat, Jan 24 from Knoxville to Prague, returning Sat, Jan 31, priced at $507 found 13 hours ago
United
Sat, Jan 24 - Sat, Jan 31
TYS
Knoxville
PRG
Prague
$508 Roundtrip, found 13 hours ago
$508
Roundtrip
found 13 hours ago
Select United flight, departing Sat, Jan 24 from Knoxville to Prague, returning Sat, Jan 31, priced at $508 found 13 hours ago
American Airlines
Sat, Jan 24 - Sat, Jan 31
TYS
Knoxville
PRG
Prague
$508 Roundtrip, found 13 hours ago
$508
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Sat, Jan 24 from Knoxville to Prague, returning Sat, Jan 31, priced at $508 found 13 hours ago
United
Sat, Jan 24 - Sat, Jan 31
TYS
Knoxville
PRG
Prague
$509 Roundtrip, found 13 hours ago
$509
Roundtrip
found 13 hours ago
Select United flight, departing Sat, Jan 24 from Knoxville to Prague, returning Sat, Jan 31, priced at $509 found 13 hours ago
British Airways
Sat, Jan 24 - Sat, Jan 31
TYS
Knoxville
PRG
Prague
$510 Roundtrip, found 13 hours ago
$510
Roundtrip
found 13 hours ago
Select British Airways flight, departing Sat, Jan 24 from Knoxville to Prague, returning Sat, Jan 31, priced at $510 found 13 hours ago
Delta
Sat, Jan 24 - Sat, Jan 31
TYS
Knoxville
PRG
Prague
$512 Roundtrip, found 13 hours ago
$512
Roundtrip
found 13 hours ago
Select Delta flight, departing Sat, Jan 24 from Knoxville to Prague, returning Sat, Jan 31, priced at $512 found 13 hours ago
Delta
Sat, Jan 24 - Sat, Jan 31
TYS
Knoxville
PRG
Prague
$518 Roundtrip, found 13 hours ago
$518
Roundtrip
found 13 hours ago
Select Delta flight, departing Sat, Jan 24 from Knoxville to Prague, returning Sat, Jan 31, priced at $518 found 13 hours ago

Alternative airports near Prague

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Vaclav Havel PRG. Cheapest and Closest option available. Average driving time to city center is 19 minutes. Flights from $665
PRG
Vaclav Havel
CheapestClosest
Average driving time to city center19 min
Flights from $665

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG) cost?
Lock in a cheap one-way flight from $405 or cheap return flight from $505 from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG)?
December is the cheapest month to fly from TYS to PRG. Traveling during quieter months is often the key to scoring lower fares.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from TYS to PRG. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG)?
Direct flights from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TYS to PRG?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a number of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG)?
Book a flight from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG) last-minute?
Last-minute fares from TYS to PRG are generally more expensive. To secure the best prices, start looking for flights ahead of time. That said, if you can play around with your travel dates, it's possible to land a cheap ticket right before you leave.
Is it cheaper to book a TYS to PRG flight and hotel package?
You'll generally save money by securing a TYS to PRG flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. Once you've chosen your preferred flights and accommodations, you can add extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Vaclav Havel Airport (PRG)?
Usually, it's possible to reschedule or cancel your TYS to PRG flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
McGhee Tyson
Destination airport
Vaclav Havel
Airlines serving
Aer Lingus, Air Canada, American Airlines, British Airways, Brussels Airlines, Delta, Finnair, KLM, Lufthansa, Scandinavian Airlines, United
Roundtrip price
$505
Distance
4699 mi

Book with confidence

Knoxville to Prague Flights

The cheapest times to fly from Knoxville to Prague

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Prague are during the month of December. You can find some of the cheapest flights from Knoxville to Prague with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Prague

Sunday is one of the best days to book for cheap flights from Knoxville to Prague: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Prague

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Prague in 2025. You can also book with separate airlines for your outbound and return journeys, from $405 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Prague flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Prague airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Prague Flights

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*Available to One Key members.