$685 Cheap Flights from Quito (UIO) to Santander (SDR)

View $685 flight on Tue, Dec 9, 2025Opens in a new window

Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Santander (SDR)

Cheap Flights from Quito to Santander (UIO-SDR)

Prices were available within the past 7 days and start at $685 for one-way flights and $1,606 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Mon, Oct 6 - Fri, Oct 10
UIO
Quito
SDR
Santander
$1,606 Roundtrip, found 6 days ago
$1,606
Roundtrip
found 6 days ago
Select Iberia flight, departing Mon, Oct 6 from Quito to Santander, returning Fri, Oct 10, priced at $1,606 found 6 days ago
Iberia
Mon, Oct 6 - Fri, Oct 10
UIO
Quito
SDR
Santander
$1,646 Roundtrip, found 6 days ago
$1,646
Roundtrip
found 6 days ago
Select Iberia flight, departing Mon, Oct 6 from Quito to Santander, returning Fri, Oct 10, priced at $1,646 found 6 days ago
Iberia
Mon, Oct 6 - Fri, Oct 10
UIO
Quito
SDR
Santander
$1,686 Roundtrip, found 6 days ago
$1,686
Roundtrip
found 6 days ago
Select Iberia flight, departing Mon, Oct 6 from Quito to Santander, returning Fri, Oct 10, priced at $1,686 found 6 days ago
Iberia
Mon, Oct 6 - Fri, Oct 10
UIO
Quito
SDR
Santander
$1,687 Roundtrip, found 6 days ago
$1,687
Roundtrip
found 6 days ago
Select Iberia flight, departing Mon, Oct 6 from Quito to Santander, returning Fri, Oct 10, priced at $1,687 found 6 days ago
LATAM Airlines Group
Mon, Oct 6 - Fri, Oct 10
UIO
Quito
SDR
Santander
$1,705 Roundtrip, found 6 days ago
$1,705
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Mon, Oct 6 from Quito to Santander, returning Fri, Oct 10, priced at $1,705 found 6 days ago
LATAM Airlines Group
Mon, Oct 6 - Fri, Oct 10
UIO
Quito
SDR
Santander
$1,716 Roundtrip, found 6 days ago
$1,716
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Mon, Oct 6 from Quito to Santander, returning Fri, Oct 10, priced at $1,716 found 6 days ago
LATAM Airlines Group
Mon, Oct 6 - Fri, Oct 10
UIO
Quito
SDR
Santander
$1,725 Roundtrip, found 6 days ago
$1,725
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Mon, Oct 6 from Quito to Santander, returning Fri, Oct 10, priced at $1,725 found 6 days ago
Iberia
Mon, Oct 6 - Fri, Oct 10
UIO
Quito
SDR
Santander
$1,726 Roundtrip, found 6 days ago
$1,726
Roundtrip
found 6 days ago
Select Iberia flight, departing Mon, Oct 6 from Quito to Santander, returning Fri, Oct 10, priced at $1,726 found 6 days ago
LATAM Airlines Group
Mon, Oct 6 - Fri, Oct 10
UIO
Quito
SDR
Santander
$1,834 Roundtrip, found 6 days ago
$1,834
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Mon, Oct 6 from Quito to Santander, returning Fri, Oct 10, priced at $1,834 found 6 days ago
LATAM Airlines Group
Mon, Oct 6 - Fri, Oct 10
UIO
Quito
SDR
Santander
$1,844 Roundtrip, found 6 days ago
$1,844
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Mon, Oct 6 from Quito to Santander, returning Fri, Oct 10, priced at $1,844 found 6 days ago

Frequently asked questions

How much does a flight from Mariscal Sucre Intl. Airport (UIO) to Santander Airport (SDR) cost?
Get a cheap one-way flight from $685 or cheap return flight from $1,606 from Mariscal Sucre Intl. Airport (UIO) to Santander Airport (SDR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Mariscal Sucre Intl. Airport (UIO) to Santander Airport (SDR)?
The cheapest month to fly from UIO to SDR is October, when demand is low. Off-peak months are usually when better flight deals are available between these airports.
What is the cheapest airline that flies from Mariscal Sucre Intl. Airport (UIO) to Santander Airport (SDR)?
To find the cheapest airline that'll fly you from UIO to SDR, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Mariscal Sucre Intl. Airport (UIO) to Santander Airport (SDR)?
You'll have to catch a flight with a layover if you're traveling from Mariscal Sucre Intl. Airport (UIO) to Santander Airport (SDR). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from UIO to SDR?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can change based on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mariscal Sucre Intl. Airport (UIO) to Santander Airport (SDR)?
To avoid possible delays on the Mariscal Sucre Intl. Airport (UIO) to Santander Airport (SDR) route, fly before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mariscal Sucre Intl. Airport (UIO) to Santander Airport (SDR) last-minute?
Booking your plane ticket from UIO to SDR shortly before your getaway is typically more expensive. But if there's some wiggle room with your travel times and dates, you could score a cheap last-minute fare.
Is it cheaper to book an UIO to SDR flight and hotel package?
Compared with arranging flights and hotels separately, booking an UIO to SDR flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one convenient place takes the hassle out of travel planning. Simply pick your flights and choose from our extensive range of stays, then personalize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Mariscal Sucre Intl. Airport (UIO) to Santander Airport (SDR)?
In most cases, you can cancel or modify your UIO to SDR flight. However, additional charges may apply, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you'd like further details, head to our Customer Service portal.

Travel information

Travel information

Origin airport
Mariscal Sucre Intl.
Destination airport
Santander
Roundtrip price
$1,605
Distance
5452 mi

Book with confidence

Book with confidence

Quito to Santander Flights

The cheapest times to fly from Quito to Santander

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Quito to Santander are during the month of October. You can find some of the cheapest flights from Quito to Santander with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Quito to Santander

Sunday is one of the best days to book for cheap flights from Quito to Santander: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Quito to Santander

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Quito to Santander in 2025. You can also book with separate airlines for your outbound and return journeys, from $685 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Quito to Santander flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Quito to Santander airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Quito to Santander Flights

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*Available to One Key members.