Title: Isla Loma Partida Luxury Vacations 2026 | Expedia.com ![](https://images.trvl-media.com/place/6246124/0ff5f005-6032-40dc-9075-f437c081a55f.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Isla Loma Partida Luxury Vacations ## Book a Luxury Hotel + Flight or Car together to unlock savings Photo by Gloria Reichlin - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Top Luxury vacation packages in Isla Loma Partida Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $827 per person Jun 17 - Jun 21 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (5,182 reviews) Breakfast was really good 5 stars only negative was the pool bar and face cloths. Other than that property is beyond nice Reviewed on Apr 5, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/786350eb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo $921 per person May 29 - Jun 1 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,000 reviews) Breakfast was good, staff friendly, good selection. Reviewed on Apr 2, 2026 ![Hotel Plaza Herrera](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/68c712fa_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Plaza Herrera Casco Viejo $928 per person May 29 - Jun 1 found 17 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9.8/10 Exceptional! (34 reviews) Internet was good. Suite was spacious. Shower and clothing closet on a seperate floor from bedroom. Ceiling fan was quiet and finctioning. A/C also quiet and functioning. Deck fan operates on a chain that was to short. Hammock on the deck takes alot of space where some decent seating and a small table might be. Great view of the park and street activity. Location is not know to Uber. Early morning coffee is available. Paid for morning breakfast with room online ... used 1 of 2 breakfasts, no credit offered. Breakfast quality is reasonable and tasted good. Staff are probably best asset at this property. They try very hard to make guests welcome amd comfortable. I did not feel like was being worked for an expected tip at all. Reviewed on Mar 24, 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco $977 per person Jun 17 - Jun 21 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 8.4/10 Very Good! (1,482 reviews) Please change the information associated with this Hotel. Deposit is $300.00, not $200.00\. There is no laundry facility; only laundry service is available, which is quite inconvenient. Very few people are bilingual. The breakfast is the same every day. Toiletries and towels were supplied sparingly. The mini fridge did not work, and the replacement did not work as well. Room service is not an option if you want your food at least warm. Reviewed on Apr 5, 2026 ![Radisson Riviera Panama](https://images.trvl-media.com/lodging/113000000/112080000/112075500/112075473/00458f1e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Radisson Riviera Panama $990 per person Jun 27 - Jul 4 found 10 hours ago Roundtrip flight included New York (JFK) to Panama City (PTY) 8.6/10 Excellent! (129 reviews) Great and lovely place!!! The staff was so helpful even when I had some water temperature issues it was a great stay, if you’re looking for activities as a solo traveler maybe try another resort since most of the excursions you need more than 1 person. Reviewed on Apr 1, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla Loma Partida [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-06/2026-05-13/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=BOC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Luxury vacations in Isla Loma Partida Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $827 per person Jun 17 - Jun 21 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (5,182 reviews) Breakfast was really good 5 stars only negative was the pool bar and face cloths. Other than that property is beyond nice Reviewed on Apr 5, 2026 ![Hotel La Compania Del Valle](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/0362f822_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel La Compania Del Valle $1,359 per person Jun 27 - Jul 4 found 10 hours ago Roundtrip flight included New York (JFK) to Panama City (PTY) 9.8/10 Exceptional! (100 reviews) Brand new property with clean spacious rooms. Ample storage in the room and large bathroom with walk in shower and Molton brown toiletries. There was complimentary bottled water although the tap water is safe to drink, and 6 complimentary coffee pods a day. The yoga instructor was excellent and the yoga was complimentary 9am Thursday to Monday on a roof terrace on the spa. There is a roof terrace bar with amazing views of the surrounding mountains with complimentary drinks for guests each evening 5pm to 7pm which was a really nice touch. All the staff are professional and friendly. The breakfasts are excellent quality and lots of variety. The dinners in the terra vegetarian restaurant and tempo restaurants were excellent quality. We didn’t eat in fuego so can’t comment on that. The food prices are at the higher end but all great quality. We paid around $70-80 for 2 people for 2 courses each and 1 drink each. Our only criticism was the room rate included breakfast however we were charged extra ($30 for 2) for a takeout breakfast on the day we had an early pick up for a trip out with a guide which was a bit steep given the room rate. There were lots of birds in the area and the hotel could attract many to the gardens/grounds if the hummingbird feeders were regularly replenished (they were practically empty our full 5 day stay). A suggestion would be to use up any left over fruit such as papaya or banana to set up a feeding station for wild birds in the hotel gardens Reviewed on Mar 20, 2026 ![Hyatt Regency Panama City](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/616200e0_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Regency Panama City Bella Vista $931 per person Jun 17 - Jun 21 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9.8/10 Exceptional! (217 reviews) The hotel is lovely, it’s a shame that the staff service doesn’t reflect. Our check in process by the check in staff was very cold. I had already messaged the hotel as we had stayed there a few days prior and non of my requests were met. There was a turn down service on our last night there which seemed quite odd as it was offered before. The breakfast was good for a city hotel. Staff have to promoted about hot drinks, the time your drinks arrive you’ve almost finished breakfast. Overall a good stay. Reviewed on Apr 2, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla Loma Partida [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-06/2026-05-13/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=BOC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Luxury vacations in Isla Loma Partida Price found within the past 48 hours. Click for updated prices. ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco $859 per person Jun 16 - Jun 19 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 8.4/10 Very Good! (1,482 reviews) Please change the information associated with this Hotel. Deposit is $300.00, not $200.00\. There is no laundry facility; only laundry service is available, which is quite inconvenient. Very few people are bilingual. The breakfast is the same every day. Toiletries and towels were supplied sparingly. The mini fridge did not work, and the replacement did not work as well. Room service is not an option if you want your food at least warm. Reviewed on Apr 5, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/786350eb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo $921 per person May 29 - Jun 1 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,000 reviews) Breakfast was good, staff friendly, good selection. Reviewed on Apr 2, 2026 ![Hotel Plaza Herrera](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/68c712fa_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Plaza Herrera Casco Viejo $928 per person May 29 - Jun 1 found 17 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9.8/10 Exceptional! (34 reviews) Internet was good. Suite was spacious. Shower and clothing closet on a seperate floor from bedroom. Ceiling fan was quiet and finctioning. A/C also quiet and functioning. Deck fan operates on a chain that was to short. Hammock on the deck takes alot of space where some decent seating and a small table might be. Great view of the park and street activity. Location is not know to Uber. Early morning coffee is available. Paid for morning breakfast with room online ... used 1 of 2 breakfasts, no credit offered. Breakfast quality is reasonable and tasted good. Staff are probably best asset at this property. They try very hard to make guests welcome amd comfortable. I did not feel like was being worked for an expected tip at all. Reviewed on Mar 24, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla Loma Partida [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-06/2026-05-13/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=BOC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Luxury vacations in Isla Loma Partida Price found within the past 48 hours. Click for updated prices. ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/890b736a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites $694 per person Jun 10 - Jun 14 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9.4/10 Exceptional! (8 reviews) This is a very nice gated country club. It has great amenities and the apartment is in excellent condition and very comfortable. We only had one issue and that was with the dryer not working, which we didn’t discover until we had already washed a load of clothes. There isn’t a lobby that is staffed at this location, and it’s not clear who to contact with issues. The “check-in” occurred at the security gate as you arrive to the country club. But despite the lack of clear instructions you get when booking, I still recommend this place, especially if you have more than a one night stay, and would stay here again. Reviewed on Mar 16, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/786350eb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo $1,245 per person May 17 - May 21 found 19 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,000 reviews) Breakfast was good, staff friendly, good selection. Reviewed on Apr 2, 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco $965 per person May 20 - May 24 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 8.4/10 Very Good! (1,482 reviews) Please change the information associated with this Hotel. Deposit is $300.00, not $200.00\. There is no laundry facility; only laundry service is available, which is quite inconvenient. Very few people are bilingual. The breakfast is the same every day. Toiletries and towels were supplied sparingly. The mini fridge did not work, and the replacement did not work as well. Room service is not an option if you want your food at least warm. Reviewed on Apr 5, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla Loma Partida [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-06/2026-05-13/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=BOC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## All you need to know about luxury vacations in Isla Loma Partida #### What can I expect from a luxury Isla Loma Partida vacation? Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Isla Loma Partida vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. #### How can I find all-inclusive luxury vacation packages in Isla Loma Partida? By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5\* filter to find truly sensational stays. You barely need to lift a finger. #### Can I book a cheap Isla Loma Partida luxury vacation? Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $694\. Prices and availability are subject to change. Additional terms may apply. #### How can I book a luxury family vacation in Isla Loma Partida? Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. #### Can I book a package in Isla Loma Partida with a luxury vacation home? A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package. #### How can I find the best luxury vacation deals in Isla Loma Partida? Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months. #### Can I book a luxury holiday in Isla Loma Partida with free cancellation and/or flexible dates? Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. #### Why should I book my luxury trip to Isla Loma Partida with Expedia? A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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](https://expedia.com/Isla-Loma-Partida-Vacation-Rentals.d3000419307.Travel-Guide-VacationRentals)[ Car Rentals in Isla Loma Partida ](https://expedia.com/Car-Rentals-In-Isla-Loma-Partida.d3000419307.Car-Rental-Guide)[ Isla Loma Partida Vacations ](https://expedia.com/Isla-Loma-Partida.d3000419307.Destination-Travel-Guides) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app