Title: Isla Loma Partida Luxury Vacations 2026 | Expedia.com ![](https://images.trvl-media.com/place/6246124/0ff5f005-6032-40dc-9075-f437c081a55f.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Isla Loma Partida Luxury Vacations ## Book a Luxury Hotel + Flight or Car together to unlock savings Photo by Gloria Reichlin - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Top Luxury vacation packages in Isla Loma Partida Price found within the past 48 hours. Click for updated prices. ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Las Americas Golden Tower Panama San Francisco $884 per person May 15 - May 22 found 2 days ago Roundtrip flight included Bridgetown (BGI) to Panama City (PTY) 9/10 Wonderful! (1,017 reviews) Breakfast was fresh, staff members very nice, did not use the parking Reviewed on Mar 30, 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco Save 100% on your flight $1,050 per person May 15 - May 22 found 2 days ago Roundtrip flight included Bridgetown (BGI) to Panama City (PTY) 8.4/10 Very Good! (1,448 reviews) The hotel is beautiful with an amazing breakfast , it is in a really good location and it’s clean but they need to work on training the staff to have a better customer service specifically in the casino they are terrible all of them , we spent 7 nights at the hotel so we went every day to the casino and their staff is really bad Reviewed on Mar 30, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/786350eb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight $1,669 per person May 15 - May 22 found 2 days ago Roundtrip flight included Bridgetown (BGI) to Panama City (PTY) 9/10 Wonderful! (1,000 reviews) Great breakfast, outstanding location, lovely property. Reviewed on Mar 29, 2026 ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $892 per person May 15 - May 22 found 2 days ago Roundtrip flight included Bridgetown (BGI) to Panama City (PTY) 9/10 Wonderful! (5,100 reviews) Desayuno espectacular!!!! Habitaciones súper agradables!!! Y el personal muy amable!!! Reviewed on Mar 31, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla Loma Partida [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-01/2026-05-08/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=BOC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Luxury vacations in Isla Loma Partida Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista $892 per person May 15 - May 22 found 2 days ago Roundtrip flight included Bridgetown (BGI) to Panama City (PTY) 9/10 Wonderful! (5,100 reviews) Desayuno espectacular!!!! Habitaciones súper agradables!!! Y el personal muy amable!!! Reviewed on Mar 31, 2026 ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### W Panama Bella Vista Save 100% on your flight $1,277 per person May 15 - May 22 found 2 days ago Roundtrip flight included Bridgetown (BGI) to Panama City (PTY) 9/10 Wonderful! (1,019 reviews) Breakfast is worth it in the morning! Nice view out of the hotel. The W is next to everything. Reviewed on Mar 30, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla Loma Partida [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-01/2026-05-08/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=BOC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Luxury vacations in Isla Loma Partida Price found within the past 48 hours. Click for updated prices. ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### W Panama Bella Vista $652 per person Jun 18 - Jun 21 found 1 hour ago Roundtrip flight included Miami (MIA) to Panama City (PTY) 9/10 Wonderful! (1,019 reviews) Breakfast is worth it in the morning! Nice view out of the hotel. The W is next to everything. Reviewed on Mar 30, 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/786350eb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo $1,038 per person May 7 - May 10 found 13 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9/10 Wonderful! (1,000 reviews) Great breakfast, outstanding location, lovely property. Reviewed on Mar 29, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla Loma Partida [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-01/2026-05-08/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=BOC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Luxury vacations in Isla Loma Partida Price found within the past 48 hours. Click for updated prices. ![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Villa Botero By Casa Mojito B&B $609 per person Jun 23 - Jun 27 found 1 day ago Roundtrip non-stop flight included Miami (MIA) to Panama City (PTY) 9.8/10 Exceptional! (64 reviews) excellent breakfast every day and varied menu. nice room, had a a fridge and coffee maker, sitting area and very clean pool. walkable to beach and few restaurants - beach was very nice. Reviewed on Mar 22, 2026 ![Hotel Plaza Herrera](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/68c712fa_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Plaza Herrera Casco Viejo $1,109 per person May 6 - May 10 found 1 day ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Panama City (PTY) 9.8/10 Exceptional! (26 reviews) Internet was good. Suite was spacious. Shower and clothing closet on a seperate floor from bedroom. Ceiling fan was quiet and finctioning. A/C also quiet and functioning. Deck fan operates on a chain that was to short. Hammock on the deck takes alot of space where some decent seating and a small table might be. Great view of the park and street activity. Location is not know to Uber. Early morning coffee is available. Paid for morning breakfast with room online ... used 1 of 2 breakfasts, no credit offered. Breakfast quality is reasonable and tasted good. Staff are probably best asset at this property. They try very hard to make guests welcome amd comfortable. I did not feel like was being worked for an expected tip at all. Reviewed on Mar 24, 2026 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco $798 per person May 28 - Jun 1 found 1 day ago Roundtrip flight included Bridgetown (BGI) to Panama City (PTY) 8.4/10 Very Good! (1,448 reviews) The hotel is beautiful with an amazing breakfast , it is in a really good location and it’s clean but they need to work on training the staff to have a better customer service specifically in the casino they are terrible all of them , we spent 7 nights at the hotel so we went every day to the casino and their staff is really bad Reviewed on Mar 30, 2026 Don't see what you're looking for? See all available trips from Columbus to Isla Loma Partida [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-01/2026-05-08/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=BOC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## All you need to know about luxury vacations in Isla Loma Partida #### What can I expect from a luxury Isla Loma Partida vacation? Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Isla Loma Partida vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. #### How can I find all-inclusive luxury vacation packages in Isla Loma Partida? By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5\* filter to find truly sensational stays. You barely need to lift a finger. #### Can I book a cheap Isla Loma Partida luxury vacation? Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $609\. Prices and availability are subject to change. Additional terms may apply. #### How can I book a luxury family vacation in Isla Loma Partida? Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. #### Can I book a package in Isla Loma Partida with a luxury vacation home? A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package. #### How can I find the best luxury vacation deals in Isla Loma Partida? Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months. #### Can I book a luxury holiday in Isla Loma Partida with free cancellation and/or flexible dates? Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. #### Why should I book my luxury trip to Isla Loma Partida with Expedia? A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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](https://expedia.com/Isla-Loma-Partida-Vacation-Rentals.d3000419307.Travel-Guide-VacationRentals)[ Car Rentals in Isla Loma Partida ](https://expedia.com/Car-Rentals-In-Isla-Loma-Partida.d3000419307.Car-Rental-Guide)[ Isla Loma Partida Vacations ](https://expedia.com/Isla-Loma-Partida.d3000419307.Destination-Travel-Guides) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app