A historic city with a prominent ancient amphitheater and a hilltop church.

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Check availability on Palestrina 4 Star Hotels

Tonight
Oct 15 - Oct 16
Tomorrow
Oct 16 - Oct 17
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Palestrina 4-star hotels

An outdoor cafe with tables and chairs, a view of the street, and buildings in the background.
A modern interior with a white armchair, wooden panel wall, and a glass door leading to an outdoor balcony.
A hotel facade with a sign reading "HOTEL DELLE NAZIONI".
A hotel reception area with a wooden reception desk, a glass door entrance, and a view of the street outside.

1. Hotel Delle Nazioni

Hotel Delle Nazioni
Rome City Centre
United States
eric
$191 nightly
$227 total
Nov 8 - Nov 9
Total with taxes and fees
Hotel Delle Nazioni
A rooftop restaurant with tables set for dining, overlooking a cityscape.
A lobby with a fireplace, red and blue chairs, marble walls, and wall sconces.
A marble-floored lobby with a red carpeted staircase, a reception desk, and a red chair.
A multi-story hotel with a classic architectural style, featuring a prominent entrance and several balconies.

2. Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo
Rome City Centre
United States
Jan
$171 nightly
$205 total
Nov 14 - Nov 15
Total with taxes and fees
Bettoja Hotel Mediterraneo
A dining area with round tables and purple chairs, large windows with a city view, and a red sofa.
A multi-story hotel with a classic architectural style, featuring balconies and illuminated windows.
A terrace with a table set for dining, overlooking a cityscape with historic buildings and a prominent archway.
A bar with various drinks and bottles, a fruit bowl, and a cityscape with mountains in the background.

3. Marcella Royal Hotel - Rooftop Garden

Marcella Royal Hotel - Rooftop Garden
Rome City Centre
United Kingdom
Kelly Ann
$151 nightly
$183 total
Nov 8 - Nov 9
Total with taxes and fees
Marcella Royal Hotel - Rooftop Garden
A courtyard with outdoor seating, a statue, and surrounding buildings.
A room with green patterned sofas, a coffee table with magazines, a fireplace, and a television mounted on the wall.
A spacious lobby with a central round table, multiple seating arrangements, and red curtains.
A hotel room with a large bed, a sitting area with a chair and a small table, a desk, and a chandelier.

4. Hotel Quirinale

Hotel Quirinale
Rome City Centre
United States
Kayleigh
$148 nightly
$179 total
Nov 15 - Nov 16
Total with taxes and fees
Hotel Quirinale
An outdoor patio with wooden flooring, white and black chairs, and large umbrellas.
A hotel room with three beds, a television, a desk, and a window with curtains.
A reception desk with four individuals standing behind it, each with a laptop.
A modern hotel building with a sign for 'HOTELS' and 'La Fatalignorante Rooftop Restaurant'.

5. iQ Hotel Roma

iQ Hotel Roma
Rome City Centre
United States
Ronald
$237 nightly
$277 total
Nov 15 - Nov 16
Total with taxes and fees
iQ Hotel Roma
An outdoor cafe with wooden tables and chairs, surrounded by greenery and potted plants.
A modern living room with a leather sofa, a glass coffee table, and a fireplace.
A hotel room with a balcony, a dining table with a chair, and a view of a building and trees.
A modern lobby with a wooden reception desk, yellow chairs, a round table, and a bookshelf filled with books and decorative items.

6. The Hoxton, Rome

The Hoxton, Rome
Salario
United Kingdom
Kevin
$182 nightly
$217 total
Nov 15 - Nov 16
Total with taxes and fees
The Hoxton, Rome
A historic building with multiple stories, ornate architectural details, and a street in front with cars and illuminated storefronts.
A hot tub with steps and metal railings, surrounded by mosaic-tiled walls and a stone-like textured wall.
An outdoor dining area with a table set for two, a candle, and a view of a building with a tower.
A professional kitchen with stainless steel appliances, a large pot on the counter, and chefs in white uniforms.

7. Hotel Artemide

Hotel Artemide
Rome City Centre
United States
Lisa
$304 nightly
$352 total
Nov 15 - Nov 16
Total with taxes and fees
Hotel Artemide
A modern hotel dining area with white chairs, tables, and a central island with a kitchen.
A gym with treadmills, weight machines, and a green accent wall.
A modern hotel room with a white sofa, a small white table, a desk with a chair, a bed, a mirror, and a nightstand with a lamp.
A hotel room with two beds, a desk, a chair, and a large window with curtains.

8. iH Hotels Roma Z3

iH Hotels Roma Z3
Collatino
Canada
NAVEEN
$65 nightly
$88 total
Nov 8 - Nov 9
Total with taxes and fees
iH Hotels Roma Z3
An outdoor seating area with wicker chairs and tables, a 'VIVANI' sign, and greenery.
An outdoor dining area with wicker chairs, a wooden table, and string lights.
A modern bedroom with a large bed, a nightstand, a desk, and a large window.
A view through a window of a building with classical architecture, including a dome and columns.

9. Hotel 55 Fifty five

Hotel 55 Fifty five
Rome City Centre
United States
JESUS ANTONIO
$116 nightly
$144 total
Nov 15 - Nov 16
Total with taxes and fees
Hotel 55 Fifty five
A narrow alleyway with a shop on the left and a door on the right.
Living area
A modern spa room with a large bathtub, candles, and flowers.
A rooftop terrace with wicker furniture, potted plants, and a view of surrounding buildings.

10. Condotti Boutique Hotel

Condotti Boutique Hotel
Rome City Centre
United States
Diana
$152 nightly
$184 total
Nov 8 - Nov 9
Total with taxes and fees
Condotti Boutique Hotel
A balcony with a table set with two glasses of red drink, a bowl of nuts, and a vase of flowers.
A bedroom with a large bed, a brick wall, a window with a view of buildings, and a vase with flowers.
A modern living area with a staircase, a bottle of champagne, glasses, and a tray with snacks.
A hotel entrance with a reception desk, a potted plant, and a stone fountain.

11. Argentina Residenza Style Hotel

Argentina Residenza Style Hotel
Rome City Centre
United States
Nathaniel
$223 nightly
$262 total
Nov 15 - Nov 16
Total with taxes and fees
Argentina Residenza Style Hotel
A restaurant with tables set for dining, a wall of wine bottles, and autumn foliage decorations.
Two people seated on outdoor chairs on a rooftop terrace, overlooking a cityscape at dusk.
A hotel entrance with a sign indicating amenities like a place to eat and drink.
A modern, open-plan bedroom with a bed, desk, and seating area.

12. Hotel Ripa Roma

Hotel Ripa Roma
Gianicolense
Canada
Nan
$116 nightly
$144 total
Nov 8 - Nov 9
Total with taxes and fees
Hotel Ripa Roma
A balcony with a table set for two, overlooking a cityscape with domed buildings.
A hotel room with a bed, a desk with a lamp, a chair, and a view of the outside.
A hotel entrance with numbered doors, a revolving door, and two potted plants.
A bar area with a bartender, bar counter, and seating arrangement.

13. UNA Hotels Decò Roma

UNA Hotels Decò Roma
Rome City Centre
Australia
Matthew
$114 nightly
$142 total
Nov 5 - Nov 6
Total with taxes and fees
UNA Hotels Decò Roma
A rooftop dining area with a table set for two, surrounded by potted plants and overlooking historic buildings.
A modern closet with a sliding door, built-in shelves, and a hanging rack.
A modern restaurant interior with hexagonal ceiling panels, black tables, and chairs.
A modern hotel room with a large bed, a nightstand, a wall-mounted mirror, and a ceiling light fixture.

14. The Hive Hotel

The Hive Hotel
Rome City Centre
United States
Kristi
$129 nightly
$159 total
Nov 15 - Nov 16
Total with taxes and fees
The Hive Hotel
An outdoor dining area with tables set for breakfast, overlooking a cityscape with domed buildings and a tower.
A breakfast tray with croissants, eggs, bacon, and fruit on a hotel room table.
A hotel lobby with a reception desk, seating area, and a carpet with the hotel name.
A buffet with various food items, including breads, pastries, and fruits.

15. Gioberti Hotel

Gioberti Hotel
Rome City Centre
United States
John
$150 nightly
$182 total
Nov 8 - Nov 9
Total with taxes and fees
Gioberti Hotel
A building facade with a large awning, a chandelier, and potted plants.
A modern hotel lobby with a central coffee table, comfortable seating, and a bookshelf.
A modern hotel corridor with a reception desk, a dark carpet, and a minimalist design.
A modern bar area with a counter, stools, and tables.

16. Hotel Villafranca

Hotel Villafranca
Rome City Centre
United States
Ravonda
$96 nightly
$122 total
Nov 1 - Nov 2
Total with taxes and fees
Hotel Villafranca
The entrance to Hotel Napoleon with a large wooden door, a glass window above, and a sign with the hotel's name. There are two potted plants on either side of the door.
A hotel room with a bed, a desk, a chair, a mirror, and a wall-mounted TV.
A balcony with chairs, a table, potted plants, and a view of the city and mountains.
A breakfast setup with croissants, a teapot, cups, and a pitcher on a table.

17. Napoleon Hotel

Napoleon Hotel
Rome City Centre
United States
Robert
$122 nightly
$135 total
Nov 5 - Nov 6
Total with taxes and fees
Napoleon Hotel
A multi-story building with a corner entrance, featuring a boutique store named 'nina' on the ground floor.
A spacious hotel room with a large bed, a sitting area, a dining table with fruit, and a chandelier.
A room with a red chair, a sliding glass door leading to a balcony with potted plants and a view of buildings.
A reception desk with two staff members, a chandelier, and a clock on the wall.

18. Augusta Lucilla Palace

Augusta Lucilla Palace
Rome City Centre
United States
Jose
$107 nightly
$134 total
Nov 8 - Nov 9
Total with taxes and fees
Augusta Lucilla Palace
A modern bar area with a counter, bar stools, and hanging pendant lights.
A poolside area with lounge chairs, umbrellas, and a pool.
A modern multi-story hotel with curved balconies, large windows, and a landscaped courtyard.
A restaurant with round tables, green chairs, and large windows with plants.

19. The Social Hub Rome

The Social Hub Rome
Tiburtino
United Kingdom
Paul
$75 nightly
$99 total
Nov 15 - Nov 16
Total with taxes and fees
The Social Hub Rome
A rooftop bar with a panoramic city view, featuring a curved bar and seating area.
A multi-story building with classical architecture, featuring ornate balconies and multiple windows.
A couple dining at a table with a cityscape view, including a prominent dome structure.
A modern lobby with marble columns, a reception desk, and a glass partition.

20. Best Western Plus Hotel Universo

Best Western Plus Hotel Universo
Rome City Centre
United States
Van
$193 nightly
$229 total
Nov 15 - Nov 16
Total with taxes and fees
Best Western Plus Hotel Universo
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Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

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$613 nightly
$697 total
Nov 3 - Nov 4
Total with taxes and fees
9.2/10 Wonderful! (1,001 reviews)
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
InterContinental Rome Ambasciatori Palace by IHG

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$492 nightly
$563 total
Nov 15 - Nov 16
Total with taxes and fees
InterContinental Rome Ambasciatori Palace by IHG
Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World

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$430 nightly
$495 total
Nov 9 - Nov 10
Total with taxes and fees
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Palestrina

Ancient temples and Renaissance palaces await in Palestrina's historic center, where the National Archaeological Museum showcases remarkable Roman mosaics. Take a guided tour of Palazzo Barberini to see the famous Nile Mosaic, then enjoy traditional Laziale cuisine at family-run trattorias in the medieval quarter.

See all hotels in Palestrina
A historic city with a prominent ancient amphitheater and a hilltop church.

Top Palestrina Hotel Reviews

Hotel Quirinale

Hotel Quirinale

10/10 Excellent
"El Hotel tiene 150 años de fundado y está impecable, es una mezcla donde tienes mobiliarios de época con un servicio impecable. Las atenciones excelentes, el ambiente en el patio interior, sobre todo cuando hay música en vivo, buenísimo. Los desayunos son buenos y cenamos en el restaurante y fue muy bueno tanto el servicio como la cena en sí. El vino que pedimos buenísimo. La ubicación excelente, con línea de Metro en la esquina de la manzana del hotel y muy cerca de la Terminal de trenes Roma Termini. Excelente Hotel por donde quiera que lo mires."
MIGUELINA 3-night trip
Posted 2 hours ago
Hotel Quirinale
Hotel Delle Nazioni

Hotel Delle Nazioni

10/10 Excellent
"Excellent location in Rome! We loved our stay at this hotel in Oct 2026. The location was perfect, right down the "road" from the Trevi Fountain, less than a block away. The staff was friendly. We had drinks at the restaurant, street level, great for people watching. We especially loved the rooftop bar for snacks and drinks. The man working there was fabulous. Our bedroom was comfy after a day of touring Rome. The breakfast was more than we could ever eat. We felt safe the entire time. What a great place. I would stay there again! It was very clean and modern. Shops were nearby, literally on the same block. Restaurants were everywhere, we never had to look for one."
DEBORAH 3-night trip
Posted 4 hours ago
Hotel Delle Nazioni
Hotel Ripa Roma

Hotel Ripa Roma

10/10 Excellent
"This was very close to our daughter but an excellent hotel. They upgraded our room and had a lot of fun with it. The breakfast was amazing!"
Kimberly 1-night trip
Posted 5 hours ago
Hotel Ripa Roma
Aria Palace by OMNIA Hotels

Aria Palace by OMNIA Hotels

10/10 Excellent
"The staff treated us great and the property itself was very clean, no complaints. Would definitely rebook in the future!"
Nathaniel 6-night trip
Posted 1 day ago
Aria Palace by OMNIA Hotels
Hotel Artemide

Hotel Artemide

10/10 Excellent
"Beautiful hotel! We had an amazing stay!"
Crystal 2-night trip
Posted 3 days ago
Hotel Artemide
Condotti Boutique Hotel

Condotti Boutique Hotel

8/10 Good
"Lovely location. Convenient and close to everything"
Roshanak 3-night trip
Posted 3 days ago
Condotti Boutique Hotel
The Guardian Hotel

The Guardian Hotel

8/10 Good
"Clean room"
Vicente 2-night trip
Posted 3 days ago
The Guardian Hotel

Find out more about Palestrina

The beginning of any well-deserved trip kicks off with choosing a destination. Palestrina has been a popular option with guests because it offers so much to do. However, "location, location, location" applies to more than just what city where your plane lands. When you want a journey that is great from beginning to end, you need the ideal accommodation.

Properties as Stunning as the City

Palestrina saw its fair share of visitors in the last year. Expedia's review section contains reviews on which room will fulfill your desires for an astounding holiday. When you book a 4-star suite you can breathe easy knowing that these properties aim to exceed your expectations. These hotels aim to make the grounds and facilities pleasing during your vacation. You'll never need to search for a refreshing dip, gourmet meal, or to sustain your workout routine.

Rooms have been designed to keep you as cozy as possible, with amenities like ultra-comfortable bedding, specially designed bathroom products, and in-room tea or coffee. So, sit back and relax. Moreover, if you find that you're need of anything more, you can trust the staff will do their best to ensure you continue to be pleased during your time. These hotels are so lovely that you'll regret the day you have to return back home.

Book a 4-Star Hotel in Palestrina Today!

Your vacation to Palestrina should be a complete escape from your daily routine. Check out Expedia's large number of 4-star hotels in Palestrina that will take your getaway to the next level.

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