Title: The Best 5 Star Hotels in Cherokee, OK  | Expedia.com

[Cherokee Travel Guide](https://expedia.com/Cherokee.dx183820)[Hotels in Cherokee](https://expedia.com/Cherokee-Hotels.d183820.Travel-Guide-Hotels)[Vacation Rentals in Cherokee](https://expedia.com/Cherokee-Vacation-Rentals.d183820.Travel-Guide-VacationRentals)[Flights to Cherokee](https://expedia.com/Cheap-Flights-To-Cherokee.d183820.Travel-Guide-Flights)[Car Rentals in Cherokee](https://expedia.com/Car-Rentals-In-Cherokee.d183820.Car-Rental-Guide)[Cherokee Vacation Packages](https://expedia.com/Cherokee.d183820.Destination-Travel-Guides)

![Dig Sites Stretch Across Salt Plains Nat'l Wildlife Refuge, OK](https://images.trvl-media.com/place/183820/ebb76607-a598-47b5-ae5f-16ccb9576f06.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/183820/ebb76607-a598-47b5-ae5f-16ccb9576f06.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Cherokee 5 Star Hotels

Tonight

[Mar 10 - Mar 11](https://www.expedia.com/Hotel-Search?regionId=183820&startDate=2026-03-10&endDate=2026-03-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 11 - Mar 12](https://www.expedia.com/Hotel-Search?regionId=183820&startDate=2026-03-11&endDate=2026-03-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=183820&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=183820&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Learn more about Cherokee

Dig for hourglass-shaped selenite crystals at Salt Plains National Wildlife Refuge, a rare geological wonder. Great Salt Plains State Park offers excellent bird watching with over 300 species and scenic hiking trails.

[See all hotels in Cherokee](https://www.expedia.com/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25&adults=2&regionId=183820)

![Dig Sites Stretch Across Salt Plains Nat'l Wildlife Refuge, OK](https://images.trvl-media.com/place/183820/ebb76607-a598-47b5-ae5f-16ccb9576f06.jpg?impolicy=fcrop&w=900&h=572&p=1&q=high)

## Top Cherokee Hotel Reviews

## Find out more about Cherokee

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your impending break. There's no reason to delay a getaway to Cherokee any longer. You'll join the multitudes of vacationers who have made Cherokee so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve the great vacation you're dreaming about. Our 5-star hotels in Cherokee are the perfect places to relax in during your next escape.

### 5-Star Hotels in Cherokee

You'll have a wonderful time at one of these 5-star hotels. Michelin-starred restaurants, top-notch customer care, and rejuvenating spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A full-body massage to help your cares fall away? Fluffy down pillows, lip-smacking main courses, and even space for your family pet in some cases...these hotels are one-of-a-kind. 

You won't sleep and order room service the entire time, though. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Cherokee are the perfect place to rest up after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs. 

### Your Getaway Starts Today

The results are in, and Cherokee 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Decide on one of Expedia's Cherokee 5-star hotels today and settle down in total tranquility tomorrow.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Cherokee?

> - Search for the lowest price per night

### What makes a hotel 5 stars in Cherokee?

### Are there any 5-star all-inclusive resorts in Cherokee?

## Explore a world of travel with Expedia

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