Title: The Best 5 Star Hotels in Ispra from $111 | Expedia.com

[Ispra Travel Guide](https://expedia.com/Ispra.dx6048875)[Hotels in Ispra](https://expedia.com/Ispra-Hotels.d6048875.Travel-Guide-Hotels)[Vacation Rentals in Ispra](https://expedia.com/Ispra-Vacation-Rentals.d6048875.Travel-Guide-VacationRentals)[Flights to Ispra](https://expedia.com/Cheap-Flights-To-Ispra.d6048875.Travel-Guide-Flights)[Things to do in Ispra](https://expedia.com/Things-To-Do-In-Ispra.d6048875.Travel-Guide-Activities)[Car Rentals in Ispra](https://expedia.com/Car-Rentals-In-Ispra.d6048875.Car-Rental-Guide)[Ispra Vacation Packages](https://expedia.com/Ispra.d6048875.Destination-Travel-Guides)

![lake maggiore night](https://images.trvl-media.com/place/6048875/6c2e50cc-824c-4a9b-b476-54d5a223d674.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6048875/6c2e50cc-824c-4a9b-b476-54d5a223d674.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Ispra 5 Star Hotels

Tonight

[Mar 30 - Mar 31](https://www.expedia.com/Hotel-Search?regionId=6048875&startDate=2026-03-30&endDate=2026-03-31&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 31 - Apr 1](https://www.expedia.com/Hotel-Search?regionId=6048875&startDate=2026-03-31&endDate=2026-04-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6048875&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6048875&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Ispra 5-star hotels

![Front of property](https://images.trvl-media.com/lodging/1000000/30000/21400/21396/652af29a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food court](https://images.trvl-media.com/lodging/1000000/30000/21400/21396/afba7473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/30000/21400/21396/5e85c2cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21400/21396/6e692cd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grand Hotel Des Iles Borromees

[](https://www.expedia.com/Stresa-Hotels-Grand-Hotel-Des-Iles-Borromees.h21396.Hotel-Information)

Stresa

9.4/10

Exceptional

(1,000 reviews)

"Very good service . Excellent breakfast, great facility. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

olga

$253 nightly

$287 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Stresa-Hotels-Grand-Hotel-Des-Iles-Borromees.h21396.Hotel-Information)

![Balcony view](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/a63a9b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/bee644b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/94388290.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/8000000/7340000/7330400/7330325/89825982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Resort Collina d'Oro, Starhotels Collezione

[](https://www.expedia.com/Collina-DOro-Hotels-Resort-Collina-DOro.h7330325.Hotel-Information)

Collina d'Oro

9.2/10

Wonderful

(170 reviews)

"Clean and super nice! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

elizabetta

$259 nightly

$281 total

Apr 8 - Apr 9

Total with taxes and fees

[](https://www.expedia.com/Collina-DOro-Hotels-Resort-Collina-DOro.h7330325.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/5c9de641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/62d33525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/4e92b857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/50000/47200/47139/ddccecbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Principe Leopoldo

[](https://www.expedia.com/Lugano-Hotels-Villa-Principe-Leopoldo.h47139.Hotel-Information)

Loreto

9.2/10

Wonderful

(350 reviews)

"The hospitality is very attentin"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Isabella

$384 nightly

$410 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Lugano-Hotels-Villa-Principe-Leopoldo.h47139.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/800000/794100/794099/410b25e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/800000/794100/794099/91f0083d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, Turkish bath, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/1000000/800000/794100/794099/a29003e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/1000000/800000/794100/794099/def9ba8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa e Palazzo Aminta Hotel Beauty and SPA

[](https://www.expedia.com/Stresa-Hotels-Villa-E-Palazzo-Aminta-Hotel-Beauty-And-SPA.h794099.Hotel-Information)

Stresa

9.2/10

Wonderful

(346 reviews)

"An amazing hotel, service, food, accomodations, Highly recommended!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

IRINA

$304 nightly

$342 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/Stresa-Hotels-Villa-E-Palazzo-Aminta-Hotel-Beauty-And-SPA.h794099.Hotel-Information)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/45ac639e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/a3776c28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double or Twin Room, Balcony, Lake View | Lake view](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/8e586bde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/980000/972600/972505/988a8310.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Swiss Diamond Hotel & SPA

[](https://www.expedia.com/Vico-Morcote-Hotels-Swiss-Diamond-Hotel.h972505.Hotel-Information)

Vico Morcote

9.0/10

Wonderful

(436 reviews)

"Beautiful property, very friendly and helpful staff. The breakfast buffet was excellent! We had a wonderful time."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Sabrina

$388 nightly

$414 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/Vico-Morcote-Hotels-Swiss-Diamond-Hotel.h972505.Hotel-Information)

![Aerial view](https://images.trvl-media.com/lodging/1000000/530000/523000/522952/8b4040fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/530000/523000/522952/56ca90a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/530000/523000/522952/415430bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite | Lake view](https://images.trvl-media.com/lodging/1000000/530000/523000/522952/f46cf048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Relais & Chateaux Villa Crespi

[](https://www.expedia.com/Orta-San-Giulio-Hotels-Relais-Chateaux-Villa-Crespi.h522952.Hotel-Information)

Orta San Giulio

9.6/10

Exceptional

(94 reviews)

"We had a wonderful experience at the Villa Crespi."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Philippe

$410 nightly

$457 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/Orta-San-Giulio-Hotels-Relais-Chateaux-Villa-Crespi.h522952.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/6d77591e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Terrace, Lake View | Minibar, in-room safe, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/828f00e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/ea960e9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/113000000/112640000/112636700/112636609/c0f3f8f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Swiss Diamond Boutique Hotel La Romantica

[](https://www.expedia.com/Melide-Hotels-Swiss-Diamond-Boutique-Hotel-La-Romantica.h112636609.Hotel-Information)

Melide

9.8/10

Exceptional

(19 reviews)

"Beautiful location and friendly staffs are impressive. Would love to visit again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susan

$514 nightly

$545 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/Melide-Hotels-Swiss-Diamond-Boutique-Hotel-La-Romantica.h112636609.Hotel-Information)

![View from room](https://images.trvl-media.com/lodging/25000000/24050000/24046800/24046747/750c11ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/25000000/24050000/24046800/24046747/366c4dbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cocktail bar, alfresco dining, open daily](https://images.trvl-media.com/lodging/25000000/24050000/24046800/24046747/e7f92862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/25000000/24050000/24046800/24046747/95d16782.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Casa Fantini

[](https://www.expedia.com/Pella-Hotels-Hotel-Casa-Fantini.h24046747.Hotel-Information)

Pella

9.8/10

Exceptional

(32 reviews)

"Casa Fantini is a rare gem. My stay was beyond expectations in all ways. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karren

$378 nightly

$422 total

Apr 25 - Apr 26

Total with taxes and fees

[](https://www.expedia.com/Pella-Hotels-Hotel-Casa-Fantini.h24046747.Hotel-Information)

![Presidential Apartment | Terrace/patio](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930326/292b89ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Apartment | Private kitchen | Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930326/28b5e99e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930326/e121e643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/81000000/80940000/80930400/80930326/d08baeed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Swiss Hotel Apartments - Collina d'Oro

[](https://www.expedia.com/Collina-DOro-Hotels-Swiss-Hotel-Apartments-Collina-DOro.h80930326.Hotel-Information)

Collina d'Oro

10/10

Exceptional

(1 review)

[](https://www.expedia.com/Collina-DOro-Hotels-Swiss-Hotel-Apartments-Collina-DOro.h80930326.Hotel-Information)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Ispra.

![Sheraton Milan Malpensa Airport Hotel & Conference Center](https://images.trvl-media.com/lodging/4000000/3780000/3773300/3773290/9a8b6535_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Sheraton Milan Malpensa Airport Hotel & Conference Center

S.S. 336 Ferno VA

$197 nightly

$223 total

Apr 3 - Apr 4

Total with taxes and fees

9.2/10 Wonderful! (2,499 reviews)

[](https://expedia.com/Milan-Hotels-Sheraton-Milan-Malpensa-Airport-Hotel-Conference-Center.h3773290.Hotel-Information)

![Hotel Villa Malpensa](https://images.trvl-media.com/lodging/3000000/2530000/2524100/2524044/8a9987e9_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Villa Malpensa

Via Don Andrea Sacconago 1 Vizzola Ticino VA

$141 nightly

$160 total

Mar 31 - Apr 1

Total with taxes and fees

9/10 Wonderful! (1,217 reviews)

[](https://expedia.com/Milan-Hotels-Hotel-Villa-Malpensa.h2524044.Hotel-Information)

![Hotel Osteria della Pista](https://images.trvl-media.com/lodging/3000000/2530000/2523100/2523034/06441981_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Osteria della Pista

Via Verbano 1 Casorate Sempione VA

$101 nightly

$111 total

Apr 12 - Apr 13

Total with taxes and fees

9.4/10 Exceptional! (1,254 reviews)

[](https://expedia.com/Milan-Hotels-Hotel-Osteria-Della-Pista.h2523034.Hotel-Information)

Still don't see what you're looking for?

[See all properties in Ispra.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F31%2F2026&endDate=4%2F1%2F2026&regionId=6048875&star=50)

You can also use these popular filters to refine your search.

[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F31%2F2026&endDate=4%2F1%2F2026&regionId=6048875&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F31%2F2026&endDate=4%2F1%2F2026&regionId=6048875&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F31%2F2026&endDate=4%2F1%2F2026&regionId=6048875&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F31%2F2026&endDate=4%2F1%2F2026&regionId=6048875&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F31%2F2026&endDate=4%2F1%2F2026&regionId=6048875&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Ispra

Lakeside paths along Lake Maggiore offer peaceful views while the JRC Visitors' Centre showcases fascinating scientific research. Enjoy gelato at the charming harbor before taking a boat to explore the Borromean Islands in nearby Stresa.

[See all hotels in Ispra](https://www.expedia.com/Hotel-Search?startDate=2026-04-13&endDate=2026-04-14&adults=2&regionId=6048875)

![lake maggiore night](https://images.trvl-media.com/place/6048875/6c2e50cc-824c-4a9b-b476-54d5a223d674.jpg?impolicy=fcrop&w=900&h=407&p=1&q=high)

## Top Ispra Hotel Reviews

![Grand Hotel Des Iles Borromees](https://images.trvl-media.com/lodging/1000000/30000/21400/21396/652af29a_y.jpg)

### Grand Hotel Des Iles Borromees

10/10 Excellent

"Very good service . Excellent breakfast, great facility. "

[](https://expedia.com/Stresa-Hotels-Grand-Hotel-Des-Iles-Borromees.h21396.Hotel-Information)

## Find out more about Ispra

Ready for an incredible adventure? Add even more enjoyment on your next trip to Ispra by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Ispra so popular in the last year. There's no reason to delay a getaway to Ispra any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Reserve one of our 5-star hotels in Ispra and indulge in the finer things in life for a while. You deserve the great vacation you're dreaming about.

### Get a Great Deal on 5-Star Hotels in Ispra

You'll have a wonderful time at one of these 5-star hotels. Michelin-starred restaurants, concierges, and pillow-fluffing are all at the ready. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready to kick back and indulge. How do you want to relax? A concierge to help you pick out your next adventure? A Swedish massage to help your cares fall away? High thread-count sheets, lip-smacking main courses, and even spectacular views...these hotels are one-of-a-kind. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

Can't wait to get outside? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Ispra are the perfect place to rest up after an exciting day.

### Make Your Escape

The results are in, and Ispra 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Don't put off your dream vacation any longer -- Expedia can help you land a great deal on accommodation. Select one of our Ispra 5-star hotels today and settle down in the lap of luxury when you're ready.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Ispra?

> - Search for the lowest price per night from $111

### What makes a hotel 5 stars in Ispra?

### Are there any 5-star all-inclusive resorts in Ispra?

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