A pier with a boat rental sign, a colorful building, and a calm sea.

Find 5 Star Hotels in Layton, FL from $234

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Check availability on Layton 5 Star Hotels

Tonight
Oct 12 - Oct 13
Tomorrow
Oct 13 - Oct 14
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Layton 5-star hotels

A bathroom with a bathtub, a shower, and a glass door leading to a balcony with a bed and a table.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.
A tropical resort with a swimming pool, palm trees, and a waterfall.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.

1. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
United States
Morgan
$264 nightly
$297 total
Nov 3 - Nov 4
Total with taxes and fees
Cheeca Lodge & Spa
An aerial view of a resort with a central pool, multiple buildings, and a beach area with sun loungers.
A beach with white chairs and kayaks, palm trees, and a clear view of the ocean.
An aerial view of a resort with a large building, a beach, and a pier in the background.
A beach scene with two white chairs, a hammock, and palm trees.

2. Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
Marathon
United States
Clinton
$271 nightly
$305 total
Oct 18 - Oct 19
Total with taxes and fees
Isla Bella Beach Resort & Spa
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A gated entrance to a resort with palm trees and a clear sky.
A pool area with clear blue water, white lounge chairs, and palm trees.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.

3. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
United States
Christian
$558 nightly
$626 total
Oct 15 - Oct 16
Total with taxes and fees
The Islands of Islamorada
A resort pool with a view of the sea, surrounded by palm trees and lounge chairs.
A modern white building with a garage, surrounded by palm trees and a clear blue sky.
A wooden deck with a spiral staircase leading to an upper level.
A modern kitchen with white cabinetry, a marble island, and wooden bar stools.

4. Sea Glass Cove

Sea Glass Cove
Marathon
Sea Glass Cove
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Layton.
Hawks Cay Resort

Hawks Cay Resort

61 Hawks Cay Blvd Marathon FL
$272 nightly
$304 total
Oct 19 - Oct 20
Total with taxes and fees
8.2/10 Very Good! (1,004 reviews)
Hawks Cay Resort
Amara Cay Resort

Amara Cay Resort

80001 Overseas Hwy Islamorada FL
$208 nightly
$234 total
Oct 18 - Oct 19
Total with taxes and fees
8.8/10 Excellent! (1,319 reviews)
Amara Cay Resort
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

84001 Overseas Hwy Islamorada FL
$304 nightly
$342 total
Nov 3 - Nov 4
Total with taxes and fees
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Layton

Nestled in the Florida Keys, this small coastal gem invites you to explore Anne's Beach and Long Key State Park's pristine shorelines. Snorkel from Bud n' Mary's Dive Center or kayak through Curry Hammock State Park's mangroves for an authentic Keys experience.

See all hotels in Layton
A pier with a boat rental sign, a colorful building, and a calm sea.

Top Layton Hotel Reviews

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

10/10 Excellent
"8 days in the keys, 4 in Marathon and 4 in Key Largo. We started here and absolutely loved it. Front desk was polite and helpful, property/grounds were very well maintained, and we enjoyed walking directly out onto the beach from our room. The food services were a little slow, but the staff was great. (Not their fault, needed to add more staff during dinner service). Hammocks on the beach were a great touch. We left here after a few days and came up to Bakers Cay. If I could get my $ back and get back down to Isla Bella I would! Honestly confused by those who rated their stay here low."
Mandy 3-night trip
Posted 17 hours ago
Isla Bella Beach Resort & Spa

Find out more about Layton

Why not demand complete opulence during your trip to Layton? After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Layton so popular in the last year. There's no reason to delay a getaway to Layton any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Layton and get ready to enjoy the getaway of a lifetime. Don't wait any longer!

5-Star Hotels in Layton

You'll have a fantastic time at one of these 5-star hotels. Exceptional service, delicious meals, and one-on-one attention are all waiting for you. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready for a wonderful adventure. How do you want to relax? A Swedish massage to help your cares fall away? A concierge to help you make reservations at that outstanding restaurant? High thread-count sheets, piping hot coffees, and even a hot tub in the bathroom...these hotels will astonish you.

Ready for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Layton are waiting for you to rest up after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Your Getaway Starts Today

The results are in, and Layton 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Opt for one of the 5-star hotels in Layton today and relax in the lap of luxury tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Layton?
How much you pay for a 5-star hotel in Layton can vary according to when you prefer to travel and how long you plan to stay, among a range of factors. Take advantage of our price per night filter and other search tools to find the best rate on an indulgent stay.
  • Search for the lowest price per night from $234
What makes a hotel 5 stars in Layton?
In Layton, a hotel must offer a specific level of upscale conveniences to earn 5 stars. These can include on-site gyms, spas and saunas, gourmet restaurants, complimentary luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their exceptional standard of service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer extra touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Layton?
Find an indulgent getaway that includes your lodging, food, activities and entertainment in Layton with Expedia's filter tool. Search for hotels rated 5 stars and select the "All inclusive" filter. Be sure to check what's included in the upfront price. This way, you're ready to take advantage of the many perks on offer when you get there.

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