Title: The Best 5 Star Hotels in Penonome from $187 | Expedia.com [Penonome Travel Guide](https://expedia.com/Penonome.dx6058652)[Hotels in Penonome](https://expedia.com/Penonome-Hotels.d6058652.Travel-Guide-Hotels)[Vacation Rentals in Penonome](https://expedia.com/Penonome-Vacation-Rentals.d6058652.Travel-Guide-VacationRentals)[Flights to Penonome](https://expedia.com/Cheap-Flights-To-Penonome.d6058652.Travel-Guide-Flights)[Things to do in Penonome](https://expedia.com/Things-To-Do-In-Penonome.d6058652.Travel-Guide-Activities)[Car Rentals in Penonome](https://expedia.com/Car-Rentals-In-Penonome.d6058652.Car-Rental-Guide)[Penonome Vacation Packages](https://expedia.com/Penonome.d6058652.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Penonome 5 Star Hotels Tonight [Mar 22 - Mar 23](https://www.expedia.com/Hotel-Search?regionId=6058652&startDate=2026-03-22&endDate=2026-03-23&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 23 - Mar 24](https://www.expedia.com/Hotel-Search?regionId=6058652&startDate=2026-03-23&endDate=2026-03-24&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6058652&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6058652&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Penonome 5-star hotels ![12 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9da9e571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 4 Bedrooms, Resort View | Frette Italian sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/232137bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/23a76ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/60de636a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection [](https://www.expedia.com/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) El Chiru 9.2/10 Wonderful (727 reviews) "The property is beautiful and our kids loved their time in the many pools - as well as in the ocean! My one minor complaint is that the shower leaked out the bottom of the door - otherwise, everything was great!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Amy $220 nightly $242 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![Couples treatment rooms, sauna, steam room, Turkish bath](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/0362f822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/e700615b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, steam room, Turkish bath](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/c72e250d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/w5989h3988x0y0-bc4b4741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel La Compania Del Valle [](https://www.expedia.com/El-Valle-De-Anton-Hotels-Hotel-La-Compania-Del-Valle.h111207482.Hotel-Information) El Valle de Anton 9.8/10 Exceptional (98 reviews) "Wow the artwork was amazing. Loved the happy hour. Lovely hotel" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jane $259 nightly $285 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/El-Valle-De-Anton-Hotels-Hotel-La-Compania-Del-Valle.h111207482.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Penonome-Hotels.s50-0-d6058652.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Penonome-Hotels.s50-0-d6058652.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Penonome. ![Playa Blanca Beach Resort - All Inclusive](https://images.trvl-media.com/lodging/1000000/970000/967200/967117/09199a01_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Playa Blanca Beach Resort - All Inclusive 115 Km Via Interamericana Rio Hato Cocle $170 nightly $187 total Mar 25 - Mar 26 Total with taxes and fees [](https://expedia.com/Rio-Hato-Hotels-Playa-Blanca-Beach-Resort-All-Inclusive.h967117.Hotel-Information) ![Casa Simona](https://images.trvl-media.com/lodging/121000000/120710000/120707000/120706939/2c2e51f5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa Simona Calle Ranita de Oro El Valle de Antón Coclé Province [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=120706939&PinnedHotelID=120706939&HadPinnedHotel=true®ionId=6058652) [](https://expedia.com/El-Valle-De-Anton-Hotels-Casa-Simona.h120706939.Hotel-Information) ![Valle de Antòn Suites ](https://images.trvl-media.com/lodging/101000000/100200000/100199800/100199716/d4a53057_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Valle de Antòn Suites A un costado del Mercado de Artesanias El Valle de Anton Coclè [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=100199716&PinnedHotelID=100199716&HadPinnedHotel=true®ionId=6058652) [](https://expedia.com/El-Valle-De-Anton-Hotels-Valle-De-Anton-Suites.h100199716.Hotel-Information) Still don't see what you're looking for? [See all properties in Penonome.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6058652&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6058652&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6058652&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6058652&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6058652&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F23%2F2026&endDate=3%2F24%2F2026®ionId=6058652&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Penonome Known as 'the city of flowers,' Penonome welcomes visitors with its colorful Corpus Christi festival and traditional artisan workshops showcasing Panama hats. Explore the nearby El Valle de Antón volcano crater for hiking trails, or visit the Penonomé Museum to discover the region's rich indigenous heritage. [See all hotels in Penonome](https://www.expedia.com/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06&adults=2®ionId=6058652) ![Adobe](https://images.trvl-media.com/place/6058652/ba6da4af-23fc-44e9-ac06-cf4370c23785.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Penonome Hotel Reviews ![The Buenaventura Golf & Beach Resort Panama, Autograph Collection](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9da9e571_y.jpg) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection 10/10 Excellent "Great stay. The hotel is beautiful! We loved it." [](https://expedia.com/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![Hotel La Compania Del Valle](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/0362f822_y.jpg) ### Hotel La Compania Del Valle 10/10 Excellent "Brand new property with clean spacious rooms. Ample storage in the room and large bathroom with walk in shower and Molton brown toiletries. There was complimentary bottled water although the tap water is safe to drink, and 6 complimentary coffee pods a day. The yoga instructor was excellent and the yoga was complimentary 9am Thursday to Monday on a roof terrace on the spa. There is a roof terrace bar with amazing views of the surrounding mountains with complimentary drinks for guests each evening 5pm to 7pm which was a really nice touch. All the staff are professional and friendly. The breakfasts are excellent quality and lots of variety. The dinners in the terra vegetarian restaurant and tempo restaurants were excellent quality. We didn’t eat in fuego so can’t comment on that. The food prices are at the higher end but all great quality. We paid around $70-80 for 2 people for 2 courses each and 1 drink each. Our only criticism was the room rate included breakfast however we were charged extra ($30 for 2) for a takeout breakfast on the day we had an early pick up for a trip out with a guide which was a bit steep given the room rate. There were lots of birds in the area and the hotel could attract many to the gardens/grounds if the hummingbird feeders were regularly replenished (they were practically empty our full 5 day stay). A suggestion would be to use up any left over fruit such as papaya or banana to set up a feeding station for wild birds in the hotel gardens " [](https://expedia.com/El-Valle-De-Anton-Hotels-Hotel-La-Compania-Del-Valle.h111207482.Hotel-Information) ## Find out more about Penonome You enjoy the finer things in life, both at home and on vacation. Add even more pleasure on your next trip to Penonome by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. There's no reason to delay a getaway to Penonome any longer. You'll join the multitudes of vacationers who have made Penonome so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve an outstanding getaway. Our 5-star hotels in Penonome are the perfect places to relax in when you really need to escape. ### 5-Star Hotels in Penonome You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and attentive guest service are all waiting for you. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready to kick back and indulge. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A mud wrap treatment that will leave you feeling great? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. Can't wait to get outside? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Penonome are the perfect place to relax after an exciting day. ### Make Your Escape The results are in, and Penonome 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Don't put off your dream vacation any longer -- Expedia can help you land a great deal on accommodation. 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