Penonome Vacations from $842

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Your Penonome Vacation

Take the hassle out of organizing your next amazing adventure with a Penonome vacation package. Whether you're visiting for its history, food or something else, this city offers endless possibilities for fun. Fill your trip to Penonome with tours of some of its top attractions. First stop? Make a beeline for 8 de Diciembre Park. Whoever you're taking time off with and whatever the size of your budget, your ultimate Penonome vacation is just a few clicks away with Expedia.

The Latest Penonome vacation packages

Price found within the past 48 hours. Click for updated prices.
Casa Fofo Family House

Casa Fofo Family House

3 out of 5
Save 100% on your flight
Price was $1,315, price is now $842 per person
$842
per person
Dec 18 - Dec 22
found 8 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
No reviews
Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Price was $3,503, price is now $1,760 per person
$1,760
per person
Jan 6 - Jan 13
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
No reviews
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $3,598, price is now $2,132 per person
$2,132
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (997 reviews)
I had a wonderful stay at Central Hotel Panama! The hotel is historic, beautifully maintained, and exceptionally clean. From the moment we arrived, the staff were warm, friendly, and consistently reliable—we truly felt welcomed and well cared for. The location is unbeatable—right in the heart of Casco Viejo and surrounded by vibrant culture, dining, and history. As solo female travelers, we felt completely safe and at ease throughout our stay, both inside and outside the hotel. The ambience of the hotel is elegant yet inviting, with thoughtful touches that reflect the charm of Panama. I especially appreciated the peaceful atmosphere and attention to detail. I loved staying here and would gladly return—again and again. Highly recommend this hotel to anyone looking for a blend of history, comfort, and genuine hospitality in Panama City.

Reviewed on Oct 15, 2025

Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,893, price is now $1,871 per person
$1,871
per person
Dec 26 - Dec 31
found 1 hour ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.8/10 Exceptional! (21 reviews)
It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment.

Reviewed on Jul 23, 2025

Mahogany Suites

Mahogany Suites

2 out of 5
Price was $2,000, price is now $1,306 per person
$1,306
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
No reviews
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Discover the most popular places to visit in Penonome

Penonomena History and Tradition Museum

4/5(1 review)

You can spend time exploring the galleries in Penonomena History and Tradition Museum during your travels in Penonome. Amble around the area's parks or experience its museums.

Penonomena History and Tradition Museum

8 de Diciembre Park

4/5(2 reviews)

Explore the great outdoors at 8 de Diciembre Park, a lovely green space in Penonome. Take in the museums while you're in the area.

8 de Diciembre Park

What to do in Penonome

Canopy- Anton Valley

Canopy-ziplining Adventures in Anton Valley

$195
per adult
Canopy-ziplining Adventures in Anton Valley
See all activities in Penonome

Penonome Hotel Deals

Hotel Coclé

Hotel Coclé

3.5 out of 5
Via Interamericana, Iguana Mall shopping center, Penonome, Cocle
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $74 total per night from Oct 21 to Oct 22
$74 total
Oct 21 - Oct 22
Total with taxes and fees
8.6/10 Excellent! (199 reviews)
"Straight forward simlw room, not fancy, basic snd everything worked."

Reviewed on Jun 26, 2025

Hotel Coclé
Enjoy family size cozy home

Enjoy family size cozy home

Penonomé
$95 nightly
The price is $95 total per night from Oct 20 to Oct 21
$95 total
Oct 20 - Oct 21
Total with taxes and fees
10/10 Exceptional! (2 reviews)
Mike
"Excellent host and very neat and clean property and very close to center of Penonome for events. Quiet neighborhood and great wifi"

Reviewed on Mar 5, 2025

Enjoy family size cozy home
Grand Decameron Panama, A Trademark All Inclusive Resort

Grand Decameron Panama, A Trademark All Inclusive Resort

3.5 out of 5
Avenida Principal Farallon Kilometro 115, Carretera Interamericana - Penonome, Rio Hato, Cocle
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $168 total per night from Oct 28 to Oct 29
$168 total
Oct 28 - Oct 29
Total with taxes and fees
7.2/10 Good! (1,000 reviews)
"Pool,and amenities"

Reviewed on Aug 30, 2025

Grand Decameron Panama, A Trademark All Inclusive Resort
See all 331 properties in Penonome
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Penonome Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
16,300
Max Temp Winter
85ºF
Max Temp Summer
85ºF
Top Sights
Mercado de Artesanías La Pintada and 8 de Diciembre Park

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Frequently asked questions

How much does a Penonome vacation package cost?
You'll find cheap prices from $842 on Expedia for your Penonome getaway. However, a range of factors like the length of stay, the season and your choice of hotel will influence how much your vacation to Penonome costs.
What are the cheapest months to go to Penonome?
January, July and December are great times to look for cheap Penonome vacation packages. Opting to travel in less busy months means you can generally find reduced prices on hotels and flights.
How many days is enough for Penonome?
With a well-organized travel plan, you can easily hit the main Penonome attractions in a few days. But if you'd like to discover hidden spots or go on day trips, consider booking your Penonome vacation for longer.
How to find the best Penonome package deals?
Bagging a cheap Penonome package deal is a cinch with Expedia. After you've entered your trip dates and destination under our "Packages" tab, set your maximum budget, add some filters and see what's available. You can tailor your search by "Amenities," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most affordable Penonome package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Penonome vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging stays and flights separately. Better still, you can customize your Penonome getaway to fit your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Penonome?
Score fantastic discounts by reserving your flights ahead of time with Expedia. If spontaneity is more your thing, snap up one of our last-minute deals for a spur-of-the-moment Penonome escape.
How to plan a trip to Penonome?

  1. Choose your travel dates: What you'd like to do in Penonome and your preferred season can help you decide when to travel.
  2. Set a budget: Consider costs such as transportation, flights and meals when working out how much to save for your trip to Penonome. Then, select a hotel that suits your budget, whether that's an affordable option or a more upscale getaway.
  3. Organize your Penonome escape with Expedia's trip planning tool: Search for and book hotels and activities all in one place. You can also collaborate with friends and family to plan an unforgettable trip to Penonome together.
  4. Decide how long to go away for: Now that you're up to speed on Penonome, you can work out the perfect length of your vacation. Pull together a draft plan and give yourself enough time to cover everything you want to do.
  5. Bundle your airfare and accommodations: After you've settled on your trip dates and duration, book the perfect Penonome vacation package for you.
  6. Book experiences or activities in advance: Whether it's a ticket to a major attraction or a walking tour, you won't have to worry about missing out on Penonome's highlights. Find all the incredible things to do in Penonome with our dedicated activity guide.

Does Expedia offer Book Now, Pay Later Penonome vacation packages?
Secure your perfect escape to Penonome with help from our Book Now, Pay Later vacations. No need to scrimp and save or wait for payday — we've joined forces with online lender Affirm to offer you flexibility and choice. Our vacation packages with payment plans let you spread the total cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily budget for your trip and snap up bargains while they last.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.