Title: The Best 5 Star Hotels in Santa Fe  | Expedia.com

[Santa Fe Travel Guide](https://expedia.com/Santa-Fe.dx6224616)[Hotels in Santa Fe](https://expedia.com/Santa-Fe-Hotels.d6224616.Travel-Guide-Hotels)[Vacation Rentals in Santa Fe](https://expedia.com/Santa-Fe-Vacation-Rentals.d6224616.Travel-Guide-VacationRentals)[Flights to Santa Fe](https://expedia.com/Cheap-Flights-To-Santa-Fe.d6224616.Travel-Guide-Flights)[Car Rentals in Santa Fe](https://expedia.com/Car-Rentals-In-Santa-Fe.d6224616.Car-Rental-Guide)[Santa Fe Vacation Packages](https://expedia.com/Santa-Fe.d6224616.Destination-Travel-Guides)

![After the rain...](https://images.trvl-media.com/place/6224616/99065f3c-1087-4054-b969-a6cdda2d6dcf.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Binin Urlaub

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## Check availability on Santa Fe 5 Star Hotels

Tonight

[Mar 4 - Mar 5](https://www.expedia.com/Hotel-Search?regionId=6224616&startDate=2026-03-04&endDate=2026-03-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 5 - Mar 6](https://www.expedia.com/Hotel-Search?regionId=6224616&startDate=2026-03-05&endDate=2026-03-06&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6224616&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6224616&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Learn more about Santa Fe

Escape to Santa Fe! Enjoy its adventures and natural setting. 

[See all hotels in Santa Fe](https://www.expedia.com/Hotel-Search?startDate=2026-03-19&endDate=2026-03-20&adults=2&regionId=6224616)

![After the rain...](https://images.trvl-media.com/place/6224616/99065f3c-1087-4054-b969-a6cdda2d6dcf.jpg?impolicy=fcrop&w=900&h=597&p=1&q=high)

Photo by Binin Urlaub

## Top Santa Fe Hotel Reviews

## Find out more about Santa Fe

You enjoy the finer things in life, both at home and on vacation. Add an extra layer of enjoyment on your next trip to Santa Fe by treating yourself to the best of the best when it comes to lodging. It's an ideal pairing. There's no reason to delay a getaway to Santa Fe any longer. You'll join the multitudes of vacationers who have made Santa Fe so fashionable in the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Book one of Expedia's luxurious 5-star hotels in Santa Fe and get ready to enjoy the getaway of a lifetime.

### Get a Great Deal on 5-Star Hotels in Santa Fe

You'll have a fantastic time at one of these 5-star hotels. Spa treatments, delicious meals, and attentive guest service are all waiting for you. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready for a wonderful adventure. How do you want to relax? A mud wrap treatment that will leave you feeling outstanding? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A full-body massage to help your cares fall away? 

Can't wait to get outside? Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Santa Fe are waiting for you to rest up after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs. 

### Make Your Escape

The results are in, and Santa Fe 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Your great getaway is just a mouse-click away. Opt for one of Expedia's Santa Fe 5-star hotels today and settle down in luxe surroundings tomorrow.

## Explore a world of travel with Expedia

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- [Hotels near Catholic Church of Santa Fe ](https://www.expedia.com/Catholic-Church-Of-Santa-Fe-Hotels.0-l6224700-0.Travel-Guide-Filter-Hotels)
- [Hotels near Town Square ](https://www.expedia.com/Town-Square-Hotels.0-l6224711-0.Travel-Guide-Filter-Hotels)
- [Hotels near Alto de Piedra Waterfall ](https://www.expedia.com/Alto-De-Piedra-Waterfall-Hotels.0-l553248621532965236-0.Travel-Guide-Filter-Hotels)
- [Hotels near Cerro Tute ](https://www.expedia.com/Cerro-Tute-Hotels.0-l553248621532965233-0.Travel-Guide-Filter-Hotels)
- [Hotels near Quebrada Bulava ](https://www.expedia.com/Quebrada-Bulava-Hotels.0-l553248621532965235-0.Travel-Guide-Filter-Hotels)
- [Hotels near Cascada de Bermejo ](https://www.expedia.com/Cascada-De-Bermejo-Hotels.0-l553248621532965237-0.Travel-Guide-Filter-Hotels)
- [Hotels near Orchid House ](https://www.expedia.com/Orchid-House-Hotels.0-l6224705-0.Travel-Guide-Filter-Hotels)

- [Flights to El Cuay ](https://www.expedia.com/Cheap-Flights-To-El-Cuay.d829297080754270208.Travel-Guide-Flights)
- [Flights to El Alto ](https://www.expedia.com/Cheap-Flights-To-El-Alto.d829297084000657408.Travel-Guide-Flights)

- [Catholic Church of Santa Fe ](https://www.expedia.com/Catholic-Church-Of-Santa-Fe-Santa-Fe.d6224700.Vacation-Attraction)
- [Town Square ](https://www.expedia.com/Town-Square-Santa-Fe.d6224711.Vacation-Attraction)
- [Cascada de Bermejo ](https://www.expedia.com/Cascada-De-Bermejo-Santa-Fe.d553248621532965237.Vacation-Attraction)
- [Cerro Tute ](https://www.expedia.com/Cerro-Tute-Santa-Fe.d553248621532965233.Vacation-Attraction)
- [Orchid House ](https://www.expedia.com/Orchid-House-Santa-Fe.d6224705.Vacation-Attraction)
- [Quebrada Las Trancas Spa ](https://www.expedia.com/Quebrada-Las-Trancas-Spa-Santa-Fe.d553248635976022318.Vacation-Attraction)
- [Alto de Piedra Waterfall ](https://www.expedia.com/Alto-De-Piedra-Waterfall-Santa-Fe.d553248621532965236.Vacation-Attraction)

- [Car rentals near Catholic Church of Santa Fe ](https://www.expedia.com/Car-Rentals-In-Catholic-Church-Of-Santa-Fe.d6224700.Car-Rental-Guide)