Berkeley Vacations from $171
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Your Berkeley Vacation
When a city break is calling, answer it with a Berkeley vacation package. The neighborhood of Downtown St. Louis, which is great for festivals, bars and pubs and dining, makes a fantastic base for your adventures. Ready to explore your new surroundings? Blanche M. Touhill Performing Arts Center, St. Louis Mills Mall and Payne-Gentry Historical House are among the top places to visit during your trip to Berkeley. Whatever your travel plans or budget, putting together a tailored Berkeley vacation is a breeze with Expedia.
The Latest Berkeley Vacation Packages
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Reviewed on Sep 9, 2026
Remodeled and Inviting Free EV
Reviewed on Aug 7, 2026
Where to stay in Berkeley
Downtown St. Louis
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Berkeley Hotel Deals
Renaissance St. Louis Airport Hotel
"The rooms and hotel were nice."
Reviewed on Sep 9, 2026
Travelodge by Wyndham St. Louis
"Got in, no one at the desk for atleast 25 minutes. Booked a handicap king size room. They gave us a room in the 2nd floor (no elevators) the room was dirty and a double bed. Went to get our room fixed and the front desk told us they didn’t have our room anymore because the over booked it. Gave us ..."
Reviewed on Sep 8, 2026
Hyatt Regency St. Louis at The Arch
"I stayed in St Louis it was a very nice clean place the only bad thing that I seen was the beds are uncomfortable but other than that everything was Top Notch"
Reviewed on Sep 9, 2026
Stay near popular Berkeley attractions
James S. McDonnell Prologue Room
Things to do
StL's Signature "Sights and Bites" - Private Tour in St. Louis
St. Louis Ghost Tour: Sinister Sins & Shadows
