Berkeley Vacations from $340
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Your Berkeley Vacation
When a city break is calling, answer it with a Berkeley vacation package. The neighborhood of Downtown St. Louis, which is great for festivals, bars and pubs and dining, makes a fantastic base for your adventures. Ready to explore your new surroundings? Blanche M. Touhill Performing Arts Center, St. Louis Mills Mall and Payne-Gentry Historical House are among the top places to visit during your trip to Berkeley. Whatever your travel plans or budget, putting together a tailored Berkeley vacation is a breeze with Expedia.
The Latest Berkeley Vacation Packages
The Wildwood Hotel
Reviewed on Aug 19, 2026
Remodeled and Inviting Free EV
Reviewed on Aug 7, 2026
Moonrise Hotel
Reviewed on Aug 19, 2026
Where to stay in Berkeley
Downtown St. Louis
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Berkeley Hotel Deals
Renaissance St. Louis Airport Hotel
Travelodge by Wyndham St. Louis
"The staff was wonderful. However, there were fruit flies, gnats and I don't mean just a few. We checked into one room - were inundated with bugs all night. They put us in another room, plugged in a ZEVO and it wasn't any better. We ended up having to book another hotel for the rest of our stay. Just ..."
Reviewed on Aug 17, 2026
Hyatt Regency St. Louis at The Arch
"Amazing customer service and the perfect spot to visit the city"
Reviewed on Aug 19, 2026
Stay near popular Berkeley attractions
James S. McDonnell Prologue Room
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
