Berkeley Vacations from $439
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Your Berkeley Vacation
When a city break is calling, answer it with a Berkeley vacation package. The neighborhood of Downtown St. Louis, which is great for festivals, bars and pubs and dining, makes a fantastic base for your adventures. Ready to explore your new surroundings? Blanche M. Touhill Performing Arts Center, St. Louis Mills Mall and Payne-Gentry Historical House are among the top places to visit during your trip to Berkeley. Whatever your travel plans or budget, putting together a tailored Berkeley vacation is a breeze with Expedia.
The Latest Berkeley Vacation Packages
The Knight Center at Washington University
Reviewed on Sep 29, 2026
Where to stay in Berkeley
Downtown St. Louis
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Berkeley Hotel Deals
Renaissance St. Louis Airport Hotel
"Staff was great! Would come back to stay."
Reviewed on Sep 27, 2026
Clayton Plaza Hotel & Extended Stay
"Missed 3 wake up call requests. Almost missed flight connection."
Reviewed on Sep 30, 2026
Hyatt Regency St. Louis at The Arch
Stay near popular Berkeley attractions
James S. McDonnell Prologue Room
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
