Berkeley Vacations from $248

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Your Berkeley Vacation

When a city break is calling, answer it with a Berkeley vacation package. The neighborhood of Downtown St. Louis, which is great for festivals, bars and pubs and dining, makes a fantastic base for your adventures. Ready to explore your new surroundings? Blanche M. Touhill Performing Arts Center, St. Louis Mills Mall and Payne-Gentry Historical House are among the top places to visit during your trip to Berkeley. Whatever your travel plans or budget, putting together a tailored Berkeley vacation is a breeze with Expedia.

The Latest Berkeley Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

Save 100% on your flight
$248
per person
Nov 12 - Nov 14
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,657 reviews)
Residence Inn by Marriott St. Louis West County

Residence Inn by Marriott St. Louis West County

$676
per person
Nov 3 - Nov 10
found 2 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (266 reviews)
Ive stayed here before. Rooms are nice because they have a desk kitchen snd couch. Bed was not good. We stayed here because our ac went out. I called and confirmed pet friendly booked and paid for the room only to arrive and be told its $100 pet fee. Thats not fair or ok.

Reviewed on Sep 4, 2026

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

Midtown
Save 100% on your flight
$639
per person
Nov 3 - Nov 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
7.8/10 Good! (1,002 reviews)
Moonrise Hotel

Moonrise Hotel

Delmar Loop
Save 100% on your flight
$639
per person
Nov 3 - Nov 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (2,016 reviews)
Amazing hotel! The staff goes above and beyond

Reviewed on Sep 15, 2026

The Cheshire

The Cheshire

Save 100% on your flight
$628
per person
Nov 18 - Nov 23
just found
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
8.8/10 Excellent! (1,004 reviews)
Great place. Have stayed here six or more times in the last five years. Always a pleasant experience. Reasonably good breakfast. Coffee always available. Excellent staff interaction they’re all very helpful and personable. Walking distance to an excellent restaurant Basso just across the parking lot with good happy hour vibes and really good food. We’ll never stay anywhere else when we come to St. Louis

Reviewed on Sep 15, 2026

Where to stay in Berkeley

Find the best Berkeley areas and neighborhoods for the activities you enjoy most. Learn more about Berkeley
A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

4 out of top 10 points of interest in this area

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis
The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Find hotels in Clayton
A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Find hotels in Central West End
A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Find hotels in Creve Coeur
A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

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Berkeley Hotel Deals

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$111 nightly
$130 total
Oct 2 - Oct 3
Total with taxes and fees
Renaissance St. Louis Airport Hotel
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
$110 total
Oct 4 - Oct 5
Total with taxes and fees
8.8/10 Excellent! (3,398 reviews)
"We enjoyed the hotel. Lobby was beautiful and staff was helpful."

Reviewed on Sep 16, 2026

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$152 nightly
$179 total
Oct 1 - Oct 2
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
See all 2,022 properties in Berkeley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Berkeley attractions

James S. McDonnell Prologue Room

You can spend time exploring the galleries in James S. McDonnell Prologue Room during your travels in St. Louis. Discover the top-notch restaurants and acclaimed theater scene in this family-friendly area.
See properties

Things to do

The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

$175
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
Self Guided Walking & Driving Audio Tour St. Louis

Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP

$15
per traveler
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.