The Gateway Arch in St. Louis, Missouri, with the city skyline in the background.

Berkeley Vacations from $171

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Your Berkeley Vacation

When a city break is calling, answer it with a Berkeley vacation package. The neighborhood of Downtown St. Louis, which is great for festivals, bars and pubs and dining, makes a fantastic base for your adventures. Ready to explore your new surroundings? Blanche M. Touhill Performing Arts Center, St. Louis Mills Mall and Payne-Gentry Historical House are among the top places to visit during your trip to Berkeley. Whatever your travel plans or budget, putting together a tailored Berkeley vacation is a breeze with Expedia.

The Latest Berkeley Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Dec 19 - Dec 21

    Holiday Inn St. Louis Arpt West-Earth City by IHG + Flight

    Earth City
    2 nights
    3.5 star property
    7.6/10 - Good (1,000 reviews)
    "It was clean and have no complaints."
    Reviewed November 3, 2026
    Roundtrip • Atlanta (ATL) - St. Louis (STL)
    ATL - STL • Nonstop STL - ATL • Nonstop
    $217
    $171
    per traveler
    found 1 day ago
    Holiday Inn St. Louis Arpt West-Earth City by IHG
  • Dec 19 - Dec 21

    The Wildwood Hotel + Flight

    Wildwood
    2 nights
    3.5 star property
    9.2/10 - Wonderful (1,679 reviews)
    "The hotel is beautiful; we felt like we were in Europe! The room was lovely and very clean. The staff was very friendly and helpful. The location was great too, close to shopping and restaurants, walkable, felt very safe, and near a park. Having a parking garage free of charge was also great! We would definitely stay again."
    Reviewed November 5, 2026
    Roundtrip • Atlanta (ATL) - St. Louis (STL)
    ATL - STL • Nonstop STL - ATL • Nonstop
    $386
    $209
    per traveler
    found 1 day ago
    The Wildwood Hotel
  • Jan 8 - Jan 11

    Remodeled and Inviting Free EV + Flight

    Fenton
    3 nights
    2.0 star property
    9.4/10 - Exceptional (3 reviews)
    "We had a great time with my family ❤️ thank you"
    Reviewed October 12, 2026
    Roundtrip • Atlanta (ATL) - St. Louis (STL)
    ATL - STL • Nonstop STL - ATL • Nonstop
    $663
    $424
    per traveler
    found 1 day ago
    Remodeled and Inviting Free EV
  • Jan 8 - Jan 11

    The Cheshire + Flight

    Richmond Heights
    3 nights
    4.0 star property
    8.8/10 - Excellent (1,003 reviews)
    Roundtrip • Atlanta (ATL) - St. Louis (STL)
    ATL - STL • Nonstop STL - ATL • Nonstop
    $547
    $414
    per traveler
    found 1 day ago
    The Cheshire
  • Jan 8 - Jan 11

    The Knight Center at Washington University + Flight

    St. Louis
    3 nights
    2.5 star property
    9.4/10 - Exceptional (720 reviews)
    Roundtrip • Atlanta (ATL) - St. Louis (STL)
    ATL - STL • Nonstop STL - ATL • Nonstop
    $417
    $322
    per traveler
    found 1 day ago
    The Knight Center at Washington University

Where to stay in Berkeley

Find the best Berkeley areas and neighborhoods for the activities you enjoy most. Learn more about Berkeley
Learn more about Berkeley

Downtown St. Louis

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Discover the most popular places to visit in Berkeley

What to do near Berkeley

Berkeley Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.