A steel bridge with a sunset in the background.

Book Cairo Bed & Breakfast

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals
  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings
  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Next weekend
In two weeks
In one month
In two months
No exact matches found, but these alternatives could be just right

Recommended hotels in Cairo

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (291 reviews)
"The web site said smoking rooms, this is untrue. I was fine with that, but my room smelled like a smoking room. There where cobwebs on the lamps and the tables where dirty. The shower was dirty and had a whole in the ceiling. The outside was very dirty. I would never stay at this hotel aging. I would tell everyone to stay far away from it as they can."
United States
Cyndy
$68 nightly
The price is $75
Jul 18 - Jul 19
Total with taxes and fees
Quality Inn Cairo I-57

La Center Motel

La Center Motel
2.0 star property
La Center
7.4 out of 10, Good, (20 reviews)
"Property is located just outside of town, so very convenient yet slightly off the beaten path."
United States
Carrie
$65 nightly
The price is $70
Jul 5 - Jul 6
Total with taxes and fees
La Center Motel

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (418 reviews)
"It was not at all what I expected. The website showed a very good hotel. It was awful. I would not paid even $40/ night if I knew how awful it is. I felt bad for the ladies working on front desk."
United States
Soheila
$74 nightly
The price is $82
Jul 9 - Jul 10
Total with taxes and fees
The Riverstone Hotel Charleston-Sikeston

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (646 reviews)
"Clean rooms,"
United States
Karl
$60 nightly
The price is $66
Jul 5 - Jul 6
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (105 reviews)
"Enjoyed our stay great hospitality, everything we needed was addressed. We would highly recommend staying there. Great location "
United States
carlton h.
$265 nightly
The price is $281
Jul 5 - Jul 6
Total with taxes and fees
Charming cottage overlooking Lake Acre

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (29 reviews)
"This was an amazing property. We our stay here with our doodles while hiking and exploring Shawnee Forest. Private, comfortable and unique! "
United States
Tammy &.
$175 nightly
The price is $185
Jul 6 - Jul 7
Total with taxes and fees
Peaceful secluded cabin located near Horseshoe Lake

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
Villa Ridge
10.0 out of 10, Exceptional, (1 review)
"Nice quiet peaceful property with a large pond in the woods"
United States
Brad M.
$225 nightly
The price is $238
Jul 5 - Jul 6
Total with taxes and fees
Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Welcoming 4-bedroom house with AC in charming La Center

Welcoming 4-bedroom house with AC in charming La Center
La Center
10.0 out of 10, Exceptional, (2 reviews)
"We stayed here while working on a project, and it was honestly one of the best stays I’ve had. The house was super clean, the beds were very comfortable, and the air conditioning worked great. The neighborhood felt safe, the neighbors were friendly, and the location was very convenient with a grocery store just a couple blocks away and a great pizza place nearby.I would definitely stay here again. Highly recommend!"
United States
Tom R.
$277 nightly
The price is $297
Jul 6 - Jul 7
Total with taxes and fees
Welcoming 4-bedroom house with AC in charming La Center

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"It’s very nice and comfortable "
United States
John S.
$133 nightly
The price is $140
Jul 14 - Jul 15
Total with taxes and fees
The Rested Duck Mallard Room

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (42 reviews)
"Peaceful and suited our needs perfectly."
United States
Matthew
$133 nightly
The price is $140
Jul 14 - Jul 15
Total with taxes and fees
Cozy cabins on beautiful Horseshoe Lake

Charming Home just minutes from Interstate and Mall

Charming Home just minutes from Interstate and Mall
Kevil
10.0 out of 10, Exceptional, (24 reviews)
"Location was great. Beds were so comfortable, place was so clean and nice. Very cute place to stay. Would stay here again!"
United States
Deannena H.
$182 nightly
The price is $206
Jul 8 - Jul 9
Total with taxes and fees
Charming Home just minutes from Interstate and Mall

Beautiful Cabin Retreat

Beautiful Cabin Retreat
tamms
8.2 out of 10, Very Good, (41 reviews)
"This is a very nice, peaceful cabin. The host was very friendly and accommodating. I would definitely stay here again."
United States
Anonymous traveler
$210 nightly
The price is $223
Jul 31 - Aug 1
Total with taxes and fees
Beautiful Cabin Retreat

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
$271 nightly
The price is $290
Aug 2 - Aug 3
Total with taxes and fees
Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
Cunningham
10.0 out of 10, Exceptional, (2 reviews)
"Host was great. "
United States
Sheila C.
$273 nightly
The price is $291
Aug 2 - Aug 3
Total with taxes and fees
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Cairo Hotel Reviews

Find out more about Cairo

Cairo B&B information

Number of reviews
1,599
Accommodation
0 B&B
Lowest Price
$66
Highest Price
$297

Frequently asked questions

Searching for B&Bs in Cairo?
If you're looking for something a little different than your standard hotel experience, a stay at a bed and breakfast could be a great option for your getaway. When you want to explore some attractions in town, Mississippi River and Ohio River Valley are worth a stop.
How do you know if a B&B is the best choice for your stay?
With attentive service, opportunities to meet other guests, and of course a full breakfast to start the day, B&Bs provide a truly one-of-a-kind setting.
When should I book my B&B in Cairo?
When you're planning your stay in Cairo, be sure to take into account the year-round temperatures. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.
What is there to do in Cairo?
Spend some time exploring Mississippi River and Ohio River Valley if you're hoping to see some of the area's natural features. You might check out Fort Defiance State Park if you have time to see more of the area.
How can I get to and around Cairo?
You can map out your trip in and around Cairo ahead of time with these transportation options. Fly into Cairo, IL (CIR-Cairo Regional), which is located 4.7 mi (7.5 km) from the heart of the city. Otherwise, look for flights into Paducah, KY (PAH-Barkley Regional), which is 22.9 mi (36.8 km) away. If you'd like to explore around the area, consider renting a car to take in more sights.

Explore a world of travel with Expedia