Title: 20 Best B&B in Cairo, IL - Bed and Breakfast from $69 | Expedia.com [Cairo Travel Guide](https://expedia.com/Cairo.dx6626)[Hotels in Cairo](https://expedia.com/Cairo-Hotels.d6626.Travel-Guide-Hotels)[Vacation Rentals in Cairo](https://expedia.com/Cairo-Vacation-Rentals.d6626.Travel-Guide-VacationRentals)[Flights to Cairo](https://expedia.com/Cheap-Flights-To-Cairo.d6626.Travel-Guide-Flights)[Car Rentals in Cairo](https://expedia.com/Car-Rentals-In-Cairo.d6626.Car-Rental-Guide)[Cairo Vacation Packages](https://expedia.com/Cairo.d6626.Destination-Travel-Guides) ![Cairo Ohio River Bridge traversing over the Ohio River at sunset](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6626&startDate=2026-02-20&endDate=2026-02-22&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6626&startDate=2026-02-27&endDate=2026-03-01&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6626&startDate=2026-03-13&endDate=2026-03-15&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6626&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Cairo ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/74187a0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Iron/ironing board, free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/e2b2c624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cairo I-57 [](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) Cairo 6.6/10 (276 reviews) "The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6\. I was not satisfied at all." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ReShena $68 nightly $75 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/4d49b58b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/7498b763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/70102e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverstone Hotel [](https://www.expedia.com/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) Charleston 6.8/10 (408 reviews) "The staff was very friendly and accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arturo $70 nightly $78 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) ![Basic Double Room | Living area](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/e95f9062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/bbe54b21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room | Living area](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/dc7ca140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/f3adf3f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Center Motel [](https://www.expedia.com/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) La Center 7.8/10 Good (17 reviews) "Quiet and convenient." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alma $65 nightly $70 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) Charleston 6.8/10 (622 reviews) "Affordable for a quick one night stay. Restaurant and gas station next to hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annette $62 nightly $69 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/9b8cfc2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/2ea775b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/fe5a3b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/7ebce143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quiet Country Stay: Modern Home Near Paducah [](https://www.expedia.com/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information) Cunningham $271 nightly $290 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/09707f79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/7bfe8087.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/c221a56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/3f7db1ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming cottage overlooking Lake Acre [](https://www.expedia.com/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information) Dongola 10/10 Exceptional (102 reviews) "Great place so peaceful and relaxing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul D. $265 nightly $281 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/c1fa9596.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Books](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/e1242dbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/8482f63b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/123000000/122890000/122882400/122882332/42d2c51f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quiet Country Stay: Modern Home Near Paducah [](https://www.expedia.com/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122882332.Hotel-Information) Cunningham 10/10 Exceptional (2 reviews) "Very clean very fun stat. Great host great ammenities!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maddi T. $274 nightly $292 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122882332.Hotel-Information) ![Room, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/8720ff7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/352edf3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston [](https://www.expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) Charleston 6.6/10 (105 reviews) "Middle of nowhere hotel was ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David $64 nightly $71 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/53db6388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/85f62077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/52fdc4c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/23c71fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy cabins on beautiful Horseshoe Lake [](https://www.expedia.com/Cozy-Cabins-On-Beautiful-Horseshoe-Lake.h90331191.Hotel-Information) Olive Branch 9.8/10 Exceptional (35 reviews) "Beautiful place, host was kind and and quick to respond to messages " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa W. $133 nightly $140 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Cozy-Cabins-On-Beautiful-Horseshoe-Lake.h90331191.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/1be40475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/d47379a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/6f998875.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, bed sheets](https://images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/d4f180ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peaceful secluded cabin located near Horseshoe Lake [](https://www.expedia.com/Peaceful-Secluded-Cabin-Located-Near-Horseshoe-Lake.h109730068.Hotel-Information) Miller City 10/10 Exceptional (21 reviews) "The cabin is perfect for a quiet getaway. Location is great close to Dollar General, gas station and restaurants" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marsha G. $173 nightly $183 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/Peaceful-Secluded-Cabin-Located-Near-Horseshoe-Lake.h109730068.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90930000/90923000/90922960/46c181aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90930000/90923000/90922960/a3fcb1a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/91000000/90930000/90923000/90922960/e172b109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/91000000/90930000/90923000/90922960/8049aee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Home just minutes from Interstate and Mall [](https://www.expedia.com/Paducah-Hotels-Charming-Home.h90922960.Hotel-Information) Kevil 10/10 Exceptional (20 reviews) "We enjoyed staying here very much. Clean and close to where we wanted to be!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becky C. $165 nightly $187 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Paducah-Hotels-Charming-Home.h90922960.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/d70c82b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/29d5afe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/1959f5ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/73a1d2fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rested Duck Mallard Room [](https://www.expedia.com/The-Rested-Duck-Mallard-Room.h90331048.Hotel-Information) Olive Branch 9.4/10 Exceptional (28 reviews) "This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mike b. $133 nightly $140 total Feb 11 - Feb 12 Total with taxes and fees [](https://www.expedia.com/The-Rested-Duck-Mallard-Room.h90331048.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-24&endDate=2026-02-25®ionId=6626&adults=2&lodging=BED_AND_BREAKFAST&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCairo-Bed-And-Breakfast.d6626-aaBedAndBreakfast.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCairo-Bed-And-Breakfast.d6626-aaBedAndBreakfast.Travel-Guide-Accommodation) ## Top Cairo Hotel Reviews ![Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/bd476bf3_y.jpg) ### Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout. 10/10 Excellent "Great place to stay for our hunting trip. Host was helpful and very accommodating." [](https://expedia.com/Tamms-Hotels-Attention-Hunters-Deer-Camp.h109109006.Hotel-Information) ![Charming cottage overlooking Lake Acre](https://images.trvl-media.com/lodging/40000000/39680000/39671200/39671140/7bfe8087_y.jpg) ### Charming cottage overlooking Lake Acre 10/10 Excellent "beautiful solid cabin. Great books on the history of the area. Truly enjoyed are restful stay! I just wish it was warmer, so we could have enjoyed the amazing stars at night and just the beauty of the area. We would rent again." [](https://expedia.com/Charming-Cabin-Overlooking-5-Acre-Lake.h39671140.Hotel-Information) ![The Rested Duck Mallard Room](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/29d5afe7_y.jpg) ### The Rested Duck Mallard Room 10/10 Excellent "It’s very nice and comfortable " [](https://expedia.com/The-Rested-Duck-Mallard-Room.h90331048.Hotel-Information) ![Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286](https://images.trvl-media.com/lodging/54000000/53860000/53856300/53856204/f8ac9a8a_y.jpg) ### Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286 10/10 Excellent "We loved our stay in this country location. It was quiet and peaceful yet close enough to Paducah for shopping and restaurants. The home was spotless, and every amenity was available - basic kitchen supplies (mixer, oil, sugar, spices, and much more), lots of towels and blankets and pillows, wifi and TV, washer and dryer, and more I'm probably not thinking of.It was very cold and snowy during our visit, so we made the home a cozy place to watch movies and relax. We even had our three small dogs with us, and there was lots of yard space to walk them.If you visit here, don't miss the National Quilt Museum. It's not your grandmother's quilt - it's amazing fabric art! Oh, and we found a vegan restaurant we liked: Branch Out.Definitely recommend staying here!!!" [](https://expedia.com/Quiet-Home-On-Horse-Farm.h53856204.Hotel-Information) ![Cozy cabins on beautiful Horseshoe Lake](https://images.trvl-media.com/lodging/91000000/90340000/90331200/90331191/53db6388_y.jpg) ### Cozy cabins on beautiful Horseshoe Lake 10/10 Excellent "The cabin was great" [](https://expedia.com/Cozy-Cabins-On-Beautiful-Horseshoe-Lake.h90331191.Hotel-Information) ![Super 8 by Wyndham Charleston/Sikeston East MO](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg) ### Super 8 by Wyndham Charleston/Sikeston East MO 10/10 Excellent "Thank you " [](https://expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Peaceful secluded cabin located near Horseshoe Lake ](https://images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/b6736ddb_y.jpg) ### Peaceful secluded cabin located near Horseshoe Lake 10/10 Excellent "The cabin is perfect for a quiet getaway. Location is great close to Dollar General, gas station and restaurants" [](https://expedia.com/Peaceful-Secluded-Cabin-Located-Near-Horseshoe-Lake.h109730068.Hotel-Information) ![Quality Inn Cairo I-57](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d_y.jpg) ### Quality Inn Cairo I-57 10/10 Excellent "Break fast was excellent " [](https://expedia.com/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![La Center Motel](https://images.trvl-media.com/lodging/100000000/99670000/99665300/99665264/6218157c_y.jpg) ### La Center Motel 10/10 Excellent "The place was very clean" [](https://expedia.com/La-Center-Hotels-La-Center-Motel.h99665264.Hotel-Information) ## Find out more about Cairo ## Cairo B&B information | Number of reviews | 1,629 | | ----------------- | ----- | | Accommodation | 0 B&B | | Lowest Price | $69 | | Highest Price | $281 | ## Frequently asked questions ### Searching for B&Bs in Cairo? ### How do you know if a B&B is the best choice for your stay? ### When should I book my B&B in Cairo? ### What is there to do in Cairo? ### How can I get to and around Cairo? ## Explore a world of travel with Expedia - 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