Find all hotels by Independent in Cairo, MO from $101

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Dec 13 - Dec 14
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Dec 19 - Dec 21
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Our top choices for Cairo Independent

Classic Single Room | Individually decorated, individually furnished, desk, blackout drapes
Simple Rewards Inn Shelbina

Simple Rewards Inn Shelbina

Simple Rewards Inn Shelbina
2.0 star property
Shelbina
8.2 out of 10, Very Good, (153)
"Simple but great for a good nights sleep. "
United States
Jan
$92 nightly
The price is $101
Dec 14 - Dec 15
Total with taxes and fees
Simple Rewards Inn Shelbina
Smart TV, books
Unwind on Vine

Unwind on Vine

Unwind on Vine
Macon
9.4 out of 10, Exceptional, (22)
"The house was very nice and clean. Will stay again!!"
United States
Ashley G.
$160 nightly
The price is $160
Dec 14 - Dec 15
Total with taxes and fees
Unwind on Vine
Exterior
Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri

Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri

Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri
Macon
10.0 out of 10, Exceptional, (3)
"Cimfortable and clean. Ideal setup for our reunion."
United States
Tim and Lela S.
Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri
Terrace/patio
Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
Cairo
10.0 out of 10, Exceptional, (23)
"Very peaceful property with lots of wildlife. Beautiful lake view."
United States
Bobi N.
Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
TV
Briggs Convenience Haven, Briggs Convenience Haven

Briggs Convenience Haven, Briggs Convenience Haven

Briggs Convenience Haven, Briggs Convenience Haven
2.0 star property
Macon
10.0 out of 10, Exceptional, (4)
"Clean house with very comfortable beds. "
United States
Paul H.
$264 nightly
The price is $264
Jan 12 - Jan 13, 2026
Total with taxes and fees
Briggs Convenience Haven, Briggs Convenience Haven
Exterior
Blue Heron Hut - At the Lodges of Long Branch

Blue Heron Hut - At the Lodges of Long Branch

Blue Heron Hut - At the Lodges of Long Branch
Bevier Township
10.0 out of 10, Exceptional, (1)
"We enjoyed our stay. It was nice and clean and had everything that we needed. The host was very friendly and responsive "
United States
Ryan S.
$246 nightly
The price is $256
Dec 15 - Dec 16
Total with taxes and fees
Blue Heron Hut - At the Lodges of Long Branch
Dining
The Sundae Cottage - A Missouri Sweet Spot , beautiful views, secluded 🌻

The Sundae Cottage - A Missouri Sweet Spot , beautiful views, secluded 🌻

The Sundae Cottage - A Missouri Sweet Spot , beautiful views, secluded 🌻
New Cambria
10.0 out of 10, Exceptional, (45)
"Perfect place to stay, we enjoyed our stay, very friendly host, property was beautiful !"
United States
Vicki D.
The Sundae Cottage - A Missouri Sweet Spot , beautiful views, secluded 🌻
Exterior
Mallard Cottage - At the Lodges of Long Branch

Mallard Cottage - At the Lodges of Long Branch

Mallard Cottage - At the Lodges of Long Branch
Bevier Township
$269 nightly
The price is $279
Dec 15 - Dec 16
Total with taxes and fees
Mallard Cottage - At the Lodges of Long Branch
Exterior detail
Teal Nest - at The Lodges of Long Branch

Teal Nest - at The Lodges of Long Branch

Teal Nest - at The Lodges of Long Branch
Bevier Township
10.0 out of 10, Exceptional, (2)
"Great place to stay and relax. Great Italian Food close by -Ugo;s. Will stay here again next year"
United States
Vincent H.
$165 nightly
The price is $170
Dec 16 - Dec 17
Total with taxes and fees
Teal Nest - at The Lodges of Long Branch
Living area
Snodgrass in-town rental!

Snodgrass in-town rental!

Snodgrass in-town rental!
Macon
Snodgrass in-town rental!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cairo Hotel Reviews

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

10/10 Excellent
"Host went above and beyond to make our anniversary stay special. Cabin is always welcoming and homey."
Bobi N. 3-night trip
Posted 5 days ago
Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

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