Find all hotels by Independent in Cairo, MO from $89

Start date: Check-in selected.
To Date
End date: Check-out

Check prices for these dates

Tonight
Oct 13 - Oct 14
Tomorrow
Oct 14 - Oct 15
This weekend
Oct 17 - Oct 19
Next weekend
Oct 24 - Oct 26

Compare rooms and suites by Independent in Cairo with rates, reviews, and availability. Most hotels are fully refundable.

Simple Rewards Inn Shelbina
Individually decorated, individually furnished, desk, blackout drapes

Simple Rewards Inn Shelbina

2.0 star property
8.2 out of 10, Very Good, (151)
"Simple but great for a good nights sleep. "
$81 nightly
The price is $89
Oct 28 - Oct 29
Total with taxes and fees
Simple Rewards Inn Shelbina
R&R Guest House- Renovated Downtown Gem, Patio
Fridge, microwave, oven, stovetop

R&R Guest House- Renovated Downtown Gem, Patio

7.0 out of 10, Good, (2)
"Such a cute, clean, spacious loft. The pictures do not do it justice. We booked it for our kids coming into town for the weekend. We would definitely book it again. "
R&R Guest House- Renovated Downtown Gem, Patio
Unwind on Vine
Fridge, microwave, oven, stovetop

Unwind on Vine

9.6 out of 10, Exceptional, (18)
"Extremely happy with our visit. No issues at all. "
$160 nightly
The price is $160
Oct 14 - Oct 15
Total with taxes and fees
Unwind on Vine
The Sundae Cottage - A Missouri Sweet Spot , beautiful views, secluded 🌻
Dining

The Sundae Cottage - A Missouri Sweet Spot , beautiful views, secluded 🌻

10.0 out of 10, Exceptional, (44)
"Perfect place to stay, we enjoyed our stay, very friendly host, property was beautiful !"
The Sundae Cottage - A Missouri Sweet Spot , beautiful views, secluded 🌻
Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri
Exterior

Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri

10.0 out of 10, Exceptional, (3)
"Cimfortable and clean. Ideal setup for our reunion."
Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri
Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
Terrace/patio

Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness

10.0 out of 10, Exceptional, (20)
"Very peaceful property with lots of wildlife. Beautiful lake view."
Peaceful Lakeside Getaway with Private Dock surrounded with Serene Wilderness
Mallard Cottage - At the Lodges of Long Branch
Exterior

Mallard Cottage - At the Lodges of Long Branch

$269 nightly
The price is $279
Oct 14 - Oct 15
Total with taxes and fees
Mallard Cottage - At the Lodges of Long Branch
The Rustic Railroad Studio 5 Min to HWY 63 Kitchen + Washer/Dryer
Fridge, microwave, oven, stovetop

The Rustic Railroad Studio 5 Min to HWY 63 Kitchen + Washer/Dryer

8.0 out of 10, Very Good, (2)
"good"
$92 nightly
The price is $96
Oct 14 - Oct 15
Total with taxes and fees
The Rustic Railroad Studio 5 Min to HWY 63 Kitchen + Washer/Dryer
Spacious Country Stay for Weekend Gatherings
Private kitchen

Spacious Country Stay for Weekend Gatherings

Spacious Country Stay for Weekend Gatherings
Blue Heron Hut - At the Lodges of Long Branch
Exterior

Blue Heron Hut - At the Lodges of Long Branch

$246 nightly
The price is $256
Oct 14 - Oct 15
Total with taxes and fees
Blue Heron Hut - At the Lodges of Long Branch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Cairo Hotel Reviews

Simple Rewards Inn Shelbina

Simple Rewards Inn Shelbina

10/10 Excellent
"Simple but great for a good nights sleep. "
Jan 2-night trip
Posted 6 days ago
Simple Rewards Inn Shelbina

Explore a world of travel with Expedia