Cape Girardeau County Vacations & Trips from $630
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Your Cape Girardeau County Vacation
Travel on your own terms with a vacation package to Cape Girardeau County. Whether you're going for its family-friendly attractions, history, culture, or something else entirely, our package deals make travel planning hassle-free. You can expect to have a to-do list as long as your arm during your trip to Cape Girardeau County. One major city you'll want to spend some time in is Cape Girardeau. Quit dreaming and get packing, because your Cape Girardeau County vacation is only a few clicks away with Expedia.
Top destinations in Cape Girardeau County
Cape Girardeau
Jackson
The Latest Cape Girardeau County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Makanda Inn
$1,221
per person
Oct 22 - Oct 25
found 19 hours ago
Roundtrip flight included
Gainesville (GNV) to Cape Girardeau (CGI)
10/10 Exceptional! (39 reviews)
I travel to So. Illinois annually to visit but this is my first stay at the Makanda Inn. It will not be my last. I had a very peaceful stay- after long days of family visit and running around with the grands, it was so nice to stay here where it was quiet and relaxing. Breakfast every morning was top notch and just the right portions.
Reviewed on Jul 22, 2026
Find the Best Cape Girardeau County Vacation Packages
Cape Girardeau County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Cape Girardeau Municipal Airport (CGI) |
Top Sights | Cape Rock Park, Cape Girardeau Conservation Nature Center and Lazy L Safari Park |
Cape Girardeau County Hotel Deals
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$98 nightly
$110 total
Aug 23 - Aug 24
Total with taxes and fees
9.6/10 Exceptional! (1,006 reviews)
"Best hotel so far great customer service great breakfast awesome kickback very nice and clean love the roof top"
Reviewed on Aug 14, 2026
The Riverview
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$114 nightly
$129 total
Aug 16 - Aug 17
Total with taxes and fees
9.4/10 Exceptional! (643 reviews)
"Very well kept"
Reviewed on Aug 13, 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$84 nightly
$91 total
Aug 16 - Aug 17
Total with taxes and fees
9/10 Wonderful! (831 reviews)
"Bed was awesome sleep great but a lot of noise"
Reviewed on Aug 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Cape Girardeau County attractions
Southeast Missouri State University
8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Riverfront Bridge Park
8.8/10 (129 reviews)
Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.
Century Casino & Hotel Cape Girardeau
8.4/10 (176 reviews)
Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.
Riverfront Park
8.0/10 (2 reviews)
Riverfront Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.
Cape Splash Family Aquatic Center
8.6/10 (21 reviews)
Bring the family to Cape Splash Family Aquatic Center and enjoy this exciting amusement park in Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Hunter Valley Winery
7.4/10 (48 reviews)
You can enjoy a tasting or tour at Hunter Valley Winery during your travels to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Cape Rock Park
8.6/10 (36 reviews)
Cape Rock Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
