Name: La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Price range: $91 total
Rating: 8.8

Your Cape Girardeau County Vacation

Travel on your own terms with a vacation package to Cape Girardeau County. Whether you're going for its family-friendly attractions, history, culture, or something else entirely, our package deals make travel planning hassle-free. You can expect to have a to-do list as long as your arm during your trip to Cape Girardeau County. One major city you'll want to spend some time in is Cape Girardeau. Quit dreaming and get packing, because your Cape Girardeau County vacation is only a few clicks away with Expedia.

The Latest Cape Girardeau County Vacation Packages

Price found within the past 48 hours. Click for updated prices.

EC Reed's Mercantile and Hotel

$338

per person

Nov 26 - Nov 29

found 22 hours ago

Roundtrip flight included

Chicago (ORD) to Cape Girardeau (CGI)

9.6/10 Exceptional! (77 reviews)

Quiet small town vibe, great food and service! Definitely recommend

Reviewed on Sep 21, 2025

Rockwood Inn

$449

per person

Nov 26 - Nov 29

found 22 hours ago

Roundtrip flight included

Chicago (ORD) to Cape Girardeau (CGI)

10/10 Exceptional! (16 reviews)

The property seemed to run on its own. We never saw the staff, except for one brief meeting of the owner. The Inn is beautiful and well maintained. We were quite comfortable.

Reviewed on May 28, 2025

The Riverview

$449

per person

Nov 26 - Nov 29

found 22 hours ago

Roundtrip flight included

Chicago (ORD) to Cape Girardeau (CGI)

9.4/10 Exceptional! (416 reviews)

Newer hotel so clean. Walk-in shower with no door but works. Control is on opposite side of shower head so alittle awkward. Starbucks was nice. Front desk very accommodating. Close to old downtown but too far to walk. Railroad tracks on east side but didn’t reallly hear.

Reviewed on Oct 7, 2025

Makanda Inn

$532

per person

Nov 26 - Nov 29

found 22 hours ago

Roundtrip flight included

Chicago (ORD) to Cape Girardeau (CGI)

10/10 Exceptional! (33 reviews)

Peaceful and relaxing.

Reviewed on May 20, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

$368

per person

Nov 26 - Nov 29

found 22 hours ago

Roundtrip flight included

Chicago (ORD) to Cape Girardeau (CGI)

9.4/10 Exceptional! (1,006 reviews)

Hotel staff at checkin very friendly & helpful. Many dining options within walking distance of hotel. Beds comfy and room clean

Reviewed on Oct 2, 2025

Cape Girardeau County Essential Information

Language	English
Currency	U.S dollars
Closest Airport	Cape Girardeau Municipal Airport (CGI)
Top Sights	Cape Rock Park, Cape Girardeau Conservation Nature Center and Lazy L Safari Park

Cape Girardeau County Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive, Cape Girardeau, MO

Fully refundableReserve now, pay when you stay

$90 nightly

$102 total

Oct 19 - Oct 20

Total with taxes and fees

9.4/10 Exceptional! (1,012 reviews)

"The lady that checked me in was amazing!"

Reviewed on Oct 6, 2025

The Riverview

777 Main St, Cape Girardeau, MO

Fully refundableReserve now, pay when you stay

$136 nightly

$154 total

Oct 19 - Oct 20

Total with taxes and fees

9.2/10 Wonderful! (431 reviews)

"The rooms are always amazing! When we go in its always so nice and cool. Loved having a k-cup in my room again. This is my favorite place in cape. My only complaint would be no microwave in the room for snacks and things."

Reviewed on Oct 6, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3003 SOUTH OLD ORCHARD ROAD, Jackson, MO

Fully refundableReserve now, pay when you stay

$84 nightly

$91 total

Oct 12 - Oct 13

Total with taxes and fees

8.8/10 Excellent! (631 reviews)

"very updated a modern.nvery clean"

Reviewed on Oct 4, 2025

See all 239 properties in Cape Girardeau County

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.