Title: Cape Girardeau Vacation Packages 2026 | Expedia.com [Cape Girardeau Travel Guide](https://expedia.com/Cape-Girardeau.dx820)[Hotels in Cape Girardeau](https://expedia.com/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels)[Vacation Rentals in Cape Girardeau](https://expedia.com/Cape-Girardeau-Vacation-Rentals.d820.Travel-Guide-VacationRentals)[Flights to Cape Girardeau](https://expedia.com/Cheap-Flights-To-Cape-Girardeau.d820.Travel-Guide-Flights)[Car Rentals in Cape Girardeau](https://expedia.com/Car-Rentals-In-Cape-Girardeau.d820.Car-Rental-Guide) ![](https://images.trvl-media.com/place/820/34f5c59a-7e57-4244-94c6-c657830fc4ab.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Cape Girardeau Vacations ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Cape Girardeau Vacation Food, history, entertainment and more … There's so much to immerse yourself in with a Cape Girardeau vacation package. And with the ability to easily customize your city break, it's guaranteed to be one that's memorable. If sightseeing is on the agenda during your trip to Cape Girardeau, swing by major attractions like [Isle Casino Cape Girardeau](https://www.expedia.com/Isle-Casino-Cape-Girardeau-Cape-Girardeau.d553248621532655780.Vacation-Attraction), [Cape Rock Park](https://www.expedia.com/Cape-Rock-Park-Cape-Girardeau.d553248621532655781.Vacation-Attraction) and [Cape Girardeau Conservation Nature Center](https://www.expedia.com/Cape-Girardeau-Conservation-Nature-Center-Cape-Girardeau.d553248621532655773.Vacation-Attraction). Expedia will help you escape your routine. Tailor your vacation to Cape Girardeau to suit your travel style, whatever that may be. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_820) ### Discover the most popular places to visit in Cape Girardeau ![Panorama of Academic Hall, Southeast Missouri State University ](https://images.trvl-media.com/place/553248621554122994/3bc9a5e0-c92b-4ca4-b94a-564376156913.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Southeast Missouri State University 4.5/5(76 reviews) Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.com/Southeast-Missouri-State-University-Cape-Girardeau.d553248621554122994.Vacation-Attraction) ![View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park](https://images.trvl-media.com/place/553248621532655774/ae18e765-2c28-4c35-b4b0-74f1aaedcb22.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Riverfront Bridge Park 4.5/5(43 reviews) Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.com/Riverfront-Bridge-Park-Cape-Girardeau.d553248621532655774.Vacation-Attraction) #### Isle Casino Cape Girardeau 4.5/5(48 reviews) Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.com/Isle-Casino-Cape-Girardeau-Cape-Girardeau.d553248621532655780.Vacation-Attraction) ## Cape Girardeau Hotel Deals ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel Cape Girardeau Conference Center 3351 Percy Drive Cape Girardeau MO Fully refundableReserve now, pay when you stay $100 nightly $113 total Mar 8 - Mar 9 Total with taxes and fees 9.6/10 Exceptional! (1,006 reviews) The rooms were wonderful. The staff was wonderful super helpful for checking in during breakfast and during dinner at the pool was such a big hit with my kiddos. Everything was so clean thank you. Reviewed on Mar 2, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=17269948&PinnedHotelID=17269948&HadPinnedHotel=true®ionId=820) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Cape Girardeau 3303 Campster Drive Cape Girardeau MO Fully refundableReserve now, pay when you stay $90 nightly $102 total Mar 8 - Mar 9 Total with taxes and fees 9.4/10 Exceptional! (1,005 reviews) Great stop. Great facility and food. Reviewed on Mar 2, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=40831&PinnedHotelID=40831&HadPinnedHotel=true®ionId=820) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Riverview 777 Main St Cape Girardeau MO Fully refundableReserve now, pay when you stay $92 nightly $104 total Mar 8 - Mar 9 Total with taxes and fees 9.4/10 Exceptional! (515 reviews) Very clean. Nice staff. Reviewed on Mar 2, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=105081384&PinnedHotelID=105081384&HadPinnedHotel=true®ionId=820) [See all 169 properties in Cape Girardeau](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F3%2F2026&endDate=3%2F4%2F2026®ionId=820) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Cape Girardeau Vacation Packages ## Cape Girardeau Essential Information | Language | English | | --------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | U.S dollars | | Closest Airport | Cape Girardeau Municipal Airport (CGI) | | Population | 39,500 | | Max Temp Winter | 45ºF | | Max Temp Summer | 85ºF | | Top Sights | [Cape Splash Family Aquatic Center](https://www.expedia.com/Cape-Splash-Family-Aquatic-Center-Cape-Girardeau.d553248621532655772.Vacation-Attraction), [Hunter Valley Winery](https://www.expedia.com/Hunter-Valley-Winery-Cape-Girardeau.d553248621532655783.Vacation-Attraction) and [Steele Crest Winery](https://www.expedia.com/Steele-Crest-Winery-Jackson.d553248621554122992.Vacation-Attraction) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ Friendly Vacations [](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adventure Vacations [](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click) ![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does a Cape Girardeau vacation package cost? ### What are the cheapest months to go to Cape Girardeau? ### How many days is enough for Cape Girardeau? ### Is it worth booking a vacation package to Cape Girardeau? ### How to find the best Cape Girardeau package deals? ### Is it cheaper to book a Cape Girardeau vacation as a package? ### When to book a vacation package to Cape Girardeau? ### Does Expedia offer Book Now, Pay Later Cape Girardeau vacation packages? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near eDen Spa & Salon ](https://www.expedia.com/EDen-Spa-Salon-Hotels.0-l553248621532655776-0.Travel-Guide-Filter-Hotels) - [Hotels near Isle Casino Cape Girardeau ](https://www.expedia.com/Isle-Casino-Cape-Girardeau-Hotels.0-l553248621532655780-0.Travel-Guide-Filter-Hotels) - [Hotels near Riverfront Bridge Park ](https://www.expedia.com/Riverfront-Bridge-Park-Hotels.0-l553248621532655774-0.Travel-Guide-Filter-Hotels) - [Hotels near Southeast Missouri State University ](https://www.expedia.com/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) - [Hotels near Fort D Historic Site ](https://www.expedia.com/Fort-D-Historic-Site-Hotels.0-l553248621532655775-0.Travel-Guide-Filter-Hotels) - [Hotels near Cape Rock Park 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Indianapolis (IND) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/ind/cgi/indianapolis-to-cape-girardeau) - [Flights from Oklahoma City (OKC) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/okc/cgi/oklahoma-city-to-cape-girardeau) - [Flights from Miami (MIA) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/mia/cgi/miami-to-cape-girardeau) - [Flights from Colorado Springs (COS) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/cos/cgi/colorado-springs-to-cape-girardeau) - [Flights from Raleigh (RDU) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/rdu/cgi/raleigh-to-cape-girardeau) - [Flights from Boston (BOS) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/bos/cgi/boston-to-cape-girardeau) - [Flights from Washington (IAD) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/iad/cgi/washington-to-cape-girardeau) - [Flights from Las Vegas (LAS) to Cape Girardeau (CGI) 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](https://www.expedia.com/lp/flights/mdw/cgi/chicago-to-cape-girardeau) - [Flights from Pensacola (PNS) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/pns/cgi/pensacola-to-cape-girardeau) - [Flights from South Bend (SBN) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/sbn/cgi/south-bend-to-cape-girardeau) - [Flights from Portland (PDX) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/pdx/cgi/portland-to-cape-girardeau) - [Flights from Peoria (PIA) to Cape Girardeau (CGI) ](https://www.expedia.com/lp/flights/pia/cgi/peoria-to-cape-girardeau) - [Eden Spa & Salon ](https://www.expedia.com/EDen-Spa-Salon-Cape-Girardeau.d553248621532655776.Vacation-Attraction) - [Isle Casino Cape Girardeau ](https://www.expedia.com/Isle-Casino-Cape-Girardeau-Cape-Girardeau.d553248621532655780.Vacation-Attraction) - [Riverfront Bridge Park ](https://www.expedia.com/Riverfront-Bridge-Park-Cape-Girardeau.d553248621532655774.Vacation-Attraction) - [Southeast Missouri State University ](https://www.expedia.com/Southeast-Missouri-State-University-Cape-Girardeau.d553248621554122994.Vacation-Attraction) - [Fort D Historic Site ](https://www.expedia.com/Fort-D-Historic-Site-Cape-Girardeau.d553248621532655775.Vacation-Attraction) - [Cape Rock Park ](https://www.expedia.com/Cape-Rock-Park-Cape-Girardeau.d553248621532655781.Vacation-Attraction) - [Cape Splash Family Aquatic Center ](https://www.expedia.com/Cape-Splash-Family-Aquatic-Center-Cape-Girardeau.d553248621532655772.Vacation-Attraction) - [Car rentals near Isle Casino Cape Girardeau ](https://www.expedia.com/Car-Rentals-In-Isle-Casino-Cape-Girardeau.d553248621532655780.Car-Rental-Guide) - [Car rental Scott City Airport (CGI) ](https://www.expedia.com/Car-Rentals-In-Cape-Girardeau-Municipal.d6026978.Car-Rental-Guide) \* Savings based on package bookings compared to the price of the same components booked separately. 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