Cape Girardeau Vacations
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Your Cape Girardeau Vacation
Food, history, entertainment and more … There's so much to immerse yourself in with a Cape Girardeau vacation package. And with the ability to easily customize your city break, it's guaranteed to be one that's memorable. If sightseeing is on the agenda during your trip to Cape Girardeau, swing by major attractions like Isle Casino Cape Girardeau, Cape Rock Park and Cape Girardeau Conservation Nature Center. Expedia will help you escape your routine. Tailor your vacation to Cape Girardeau to suit your travel style, whatever that may be.
Discover the most popular places to visit in Cape Girardeau
Southeast Missouri State University
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Isle Casino Cape Girardeau
Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.
Riverfront Bridge Park
Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.
Cape Girardeau Hotel Deals
The Riverview
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $132 total per night from Jul 3 to Jul 4
$132 total
Jul 3 - Jul 4
Total includes taxes and fees
9.2/10 Wonderful! (311 reviews)
Clean
"Great clean room"
Reviewed on Jun 30, 2025
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
$90 nightly
The price is $102 total per night from Jul 6 to Jul 7
$102 total
Jul 6 - Jul 7
Total includes taxes and fees
9.4/10 Exceptional! (1,009 reviews)
"The staff was very friendly and the hotel was very clean!"
Reviewed on Jun 29, 2025
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Jul 6 to Jul 7
$81 total
Jul 6 - Jul 7
Total includes taxes and fees
9/10 Wonderful! (1,003 reviews)
"Lovely"
Reviewed on Jun 29, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Cape Girardeau Vacation Packages
Cape Girardeau Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Cape Girardeau Municipal Airport (CGI) |
Population | 39,500 |
Max Temp Winter | 45ºF |
Max Temp Summer | 85ºF |
Top Sights | Cape Splash Family Aquatic Center, Hunter Valley Winery and Steele Crest Winery |
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- Hotels near eDen Spa & Salon
- Hotels near Isle Casino Cape Girardeau
- Hotels near Riverfront Bridge Park
- Hotels near Southeast Missouri State University
- Hotels near Fort D Historic Site
- Hotels near Cape Rock Park
- Hotels near Cape Splash Family Aquatic Center
- Hotels near Cape Girardeau Conservation Nature Center
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.