
Cape Girardeau Vacations from $684
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Your Cape Girardeau Vacation
Food, history, entertainment and more … There's so much to immerse yourself in with a Cape Girardeau vacation package. And with the ability to easily customize your city break, it's guaranteed to be one that's memorable. If sightseeing is on the agenda during your trip to Cape Girardeau, swing by major attractions like Isle Casino Cape Girardeau, Cape Rock Park and Cape Girardeau Conservation Nature Center. Expedia will help you escape your routine. Tailor your vacation to Cape Girardeau to suit your travel style, whatever that may be.
The Latest Cape Girardeau vacation packages
Price found within the past 48 hours. Click for updated prices.


Makanda Inn
Price was $822, price is now $797 per person
$797
per person
Jan 13 - Jan 15
found 14 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Cape Girardeau (CGI)
10/10 Exceptional! (41 reviews)
Makanda inn is a very well maintained place. The room was very comfortable, and the staff was excellent. The breakfasts were delicious.
Reviewed on Oct 11, 2026


Candlewood Suites Cape Girardeau by IHG
Price was $711, price is now $705 per person
$705
per person
Jan 13 - Jan 15
found 14 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Cape Girardeau (CGI)
8/10 Very Good! (1,003 reviews)
The facility, grounds and staff were all amazing. Very clean and helpful.
Reviewed on Oct 26, 2026

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Cape Girardeau Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $113 total per night from Nov 8 to Nov 9
$113 total
Nov 8 - Nov 9
Total with taxes and fees
9.6/10 Exceptional! (1,000 reviews)
"Nice place to stay."
Reviewed on Nov 2, 2026

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Nov 8 to Nov 9
$81 total
Nov 8 - Nov 9
Total with taxes and fees
9.2/10 Wonderful! (1,000 reviews)
"Will stay again"
Reviewed on Nov 2, 2026

The Riverview
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $116 total per night from Nov 11 to Nov 12
$116 total
Nov 11 - Nov 12
Total with taxes and fees
9.4/10 Exceptional! (700 reviews)
"Great property"
Reviewed on Nov 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Cape Girardeau Vacation Packages
Cape Girardeau Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Cape Girardeau Municipal Airport (CGI) |
Population | 39,500 |
Max Temp Winter | 45ºF |
Max Temp Summer | 85ºF |
Top Sights | Cape Splash Family Aquatic Center, Hunter Valley Winery and Steele Crest Winery |
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- Cape Rock Park
- Crown Valley Winery
- Dexter Vacations
- Cape Splash Family Aquatic Center
- Trail of Tears State Park
- The Heritage House
- Sikeston Depot Museum
- Bernie Vacations
- Hunter Valley Winery
- Southeast Missouri State University
- Hunter-Dawson State Historic Site
- Fort D Historic Site
- Stoddard County Civil War Memorial Cemetery
- Eden Spa & Salon
- Visit Cape Girardeau
- Lake Wappapello
- Central Park
- New Madrid Historical Museum
- Silver Mine Recreation Area
- Riverfront Bridge Park
- Charleston Vacations
- Litz Park
- Weingarten Vineyard
- Bloomfield Vacations
- Marble Hill Vacations
- National Shrine of Our Lady of the Miraculous Medal
- Marston Community Center
- Sikeston Vacations
- Perryville Vacations
- Felix Valle House State Historic Site
- Luxury Car Rentals in Cape Girardeau
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.




















