Cape Girardeau Vacations from $616

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Your Cape Girardeau Vacation

Food, history, entertainment and more … There's so much to immerse yourself in with a Cape Girardeau vacation package. And with the ability to easily customize your city break, it's guaranteed to be one that's memorable. If sightseeing is on the agenda during your trip to Cape Girardeau, swing by major attractions like Isle Casino Cape Girardeau, Cape Rock Park and Cape Girardeau Conservation Nature Center. Expedia will help you escape your routine. Tailor your vacation to Cape Girardeau to suit your travel style, whatever that may be.

The Latest Cape Girardeau vacation packages

Price found within the past 48 hours. Click for updated prices.
Best Western Saluki Inn

Best Western Saluki Inn

2.5 out of 5
Price was $625, price is now $616 per person
$616
per person
Jan 2 - Jan 4
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Cape Girardeau (CGI)
7.8/10 Good! (1,006 reviews)
Perfect for what we needed it to be

Reviewed on Oct 11, 2025

Makanda Inn

Makanda Inn

3.5 out of 5
Price was $758, price is now $723 per person
$723
per person
Jan 2 - Jan 4
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Cape Girardeau (CGI)
10/10 Exceptional! (33 reviews)
Peaceful and relaxing.

Reviewed on May 20, 2025

Holiday Inn Carbondale-Conference Center by IHG

Holiday Inn Carbondale-Conference Center by IHG

3 out of 5
Price was $643, price is now $623 per person
$623
per person
Jan 2 - Jan 4
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Cape Girardeau (CGI)
8.8/10 Excellent! (601 reviews)
Nice staff, clean rooms, awesome beds and pillows!

Reviewed on Oct 9, 2025

Hampton Inn Carbondale

Hampton Inn Carbondale

2.5 out of 5
Price was $758, price is now $745 per person
$745
per person
Dec 19 - Dec 21
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Cape Girardeau (CGI)
8.4/10 Very Good! (584 reviews)
Location was under some construction process . Black out shades only went down halfway , staff provided black garbage bag and tape as solution . Left for the second night , refunded as such .

Reviewed on Oct 1, 2025

Home2 Suites by Hilton Carbondale

Home2 Suites by Hilton Carbondale

3 out of 5
Price was $659, price is now $648 per person
$648
per person
Jan 2 - Jan 4
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Cape Girardeau (CGI)
8.8/10 Excellent! (488 reviews)
The property was nice and up to date. The staff was VERY friendly and professional! Thank you!

Reviewed on Sep 14, 2025

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Discover the most popular places to visit in Cape Girardeau

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Southeast Missouri State University

Isle Casino Cape Girardeau

Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

Isle Casino Cape Girardeau

Riverfront Bridge Park

Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.

Riverfront Bridge Park

Cape Girardeau Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Oct 19 to Oct 20
$102 total
Oct 19 - Oct 20
Total with taxes and fees
9.4/10 Exceptional! (1,012 reviews)
"The lady that checked me in was amazing!"

Reviewed on Oct 6, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $143 total per night from Oct 19 to Oct 20
$143 total
Oct 19 - Oct 20
Total with taxes and fees
9.2/10 Wonderful! (431 reviews)
"The rooms are always amazing! When we go in its always so nice and cool. Loved having a k-cup in my room again. This is my favorite place in cape. My only complaint would be no microwave in the room for snacks and things."

Reviewed on Oct 6, 2025

The Riverview
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Oct 12 to Oct 13
$79 total
Oct 12 - Oct 13
Total with taxes and fees
9/10 Wonderful! (1,005 reviews)
"Close to the interstate so easy to get to when traveling. Nice property - plus that Outback Steakhouse is right next door for dining. We have stayed here numerous times over the years and always pleased."

Reviewed on Oct 9, 2025

Pear Tree Inn Cape Girardeau West
See all 167 properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cape Girardeau Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Cape Girardeau Municipal Airport (CGI)
Population
39,500
Max Temp Winter
45ºF
Max Temp Summer
85ºF
Top Sights
Cape Splash Family Aquatic Center, Hunter Valley Winery and Steele Crest Winery

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Frequently asked questions

How much does a Cape Girardeau vacation package cost?
Offering excellent value package deals from $616 on Expedia, you'll be pleasantly surprised at how much a vacation to Cape Girardeau costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Cape Girardeau?
If you're looking to score a cheap Cape Girardeau vacation package, consider traveling in March, September and November. You're likely to find lower prices on hotels and airfares during these months — perfect for a budget-friendly getaway.
How many days is enough for Cape Girardeau?
With a well-planned schedule, you can easily hit the main Cape Girardeau sights in a handful of days. But if you'd like to discover lesser-known spots or take day trips, think about booking your Cape Girardeau vacation for longer.
Is it worth booking a vacation package to Cape Girardeau?
Cape Girardeau has everything you need for the perfect break — history, culture and family-friendly attractions are just the start. Whether you want to visit sights such as Cape Rock Park and Fort D Historic Site, or venture off the beaten track, you'll have plenty to experience on your Cape Girardeau vacation.
How to find the best Cape Girardeau package deals?
Start your search for a Cape Girardeau package deal by entering your preferred travel dates and destination under our "Packages" tab. Then select some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the perfect Cape Girardeau package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Cape Girardeau adventure underway.
Is it cheaper to book a Cape Girardeau vacation as a package?
You can enjoy significant savings on your Cape Girardeau retreat by booking a tailored vacation package. Click on the "Package" heading, then enter your destination and travel dates to view the best flight and hotel prices. Bundling can save travelers hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Cape Girardeau?
If you're planning a spontaneous Cape Girardeau trip, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can land awesome deals on your flights and hotels by booking well in advance.
Does Expedia offer Book Now, Pay Later Cape Girardeau vacation packages?
If you're like us, you love exploring new places but don't love the price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the total cost of your Cape Girardeau trip over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.