Find hotels near Colleton Medical Center, Walterboro from $52

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Compare 248 hotels close to Colleton Medical Center with room rates, reviews, and availability. Most hotels are fully refundable.

Sleep Inn Walterboro I-95

2.5 star property
1.2 mi from Colleton Medical Center
7.6 out of 10, Good, (572)
"Quiet and very accesible place."
United States
Lisa
$84 nightly
The price is $94
Jan 4 - Jan 5, 2026
Total with taxes and fees
Sleep Inn Walterboro I-95

Southern Inn By OYO Walterboro I-95

2.5 star property
1.1 mi from Colleton Medical Center
7.0 out of 10, Good, (79)
"Room is badly overrated. Sink was clogged. Interior badly needs remodeled."
United States
Ronnie
$47 nightly
The price is $52
Dec 14 - Dec 15
Total with taxes and fees
Southern Inn By OYO Walterboro I-95

Travelodge by Wyndham Walterboro

2.0 star property
1.1 mi from Colleton Medical Center
6.2 out of 10, (526)
"Everything is ok "
United States
Fonda
$47 nightly
The price is $52
Dec 28 - Dec 29
Total with taxes and fees
Travelodge by Wyndham Walterboro

Super 8 by Wyndham Walterboro

2.0 star property
1.5 mi from Colleton Medical Center
6.2 out of 10, (211)
"Stay was good. "
United States
Cindy
$59 nightly
The price is $66
Dec 10 - Dec 11
Total with taxes and fees
Super 8 by Wyndham Walterboro

Red Roof Inn Walterboro

2.0 star property
3.8 mi from Colleton Medical Center
6.6 out of 10, (859)
"Always stay here on our way to the mountains "
United States
Judy
$58 nightly
The price is $66
Jan 1 - Jan 2, 2026
Total with taxes and fees
Red Roof Inn Walterboro

Baymont by Wyndham Walterboro

2.5 star property
3.9 mi from Colleton Medical Center
6.2 out of 10, (1041)
"I like the quietness. "
United States
Joseph
$47 nightly
The price is $52
Dec 7 - Dec 8
Total with taxes and fees
Baymont by Wyndham Walterboro

Hampton Inn & Suites Walterboro

2.5 star property
4.3 mi from Colleton Medical Center
9.2 out of 10, Wonderful, (1001)
"Wonderful stay!"
United States
Efrain
$152 nightly
The price is $170
Dec 14 - Dec 15
Total with taxes and fees
Hampton Inn & Suites Walterboro

Comfort Inn & Suites Walterboro I-95

2.5 star property
4.1 mi from Colleton Medical Center
8.4 out of 10, Very Good, (1001)
"Room is clean and staff was very courteous and check in was a breeze. Would stay here again"
United States
Teddy
$97 nightly
The price is $108
Dec 14 - Dec 15
Total with taxes and fees
Comfort Inn & Suites Walterboro I-95

Motel 6 Walterboro, SC

2.0 star property
4.1 mi from Colleton Medical Center
8.2 out of 10, Very Good, (1415)
"Room was spotless and the staff was excellent. Would love to stay here again. "
United States
Tina
$56 nightly
The price is $63
Dec 7 - Dec 8
Total with taxes and fees
Motel 6 Walterboro, SC

Econo Lodge

2.0 star property
3.7 mi from Colleton Medical Center
7.8 out of 10, Good, (1000)
"Great motel and great prices "
United States
Kent
$52 nightly
The price is $58
Dec 14 - Dec 15
Total with taxes and fees
Econo Lodge

Holiday Inn Exp Walterboro by IHG

2.5 star property
4.2 mi from Colleton Medical Center
8.6 out of 10, Excellent, (1000)
"Clean stay, helpful service"
United States
Imani
$148 nightly
The price is $166
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Exp Walterboro by IHG

Best Western Of Walterboro

2.5 star property
3.9 mi from Colleton Medical Center
7.6 out of 10, Good, (333)
"Room was very clean and quiet. Easy check in and check out. "
United States
Jessica
$81 nightly
The price is $91
Dec 8 - Dec 9
Total with taxes and fees
Best Western Of Walterboro

Microtel Inn & Suites by Wyndham Walterboro

2.0 star property
4.3 mi from Colleton Medical Center
8.0 out of 10, Very Good, (1003)
"Room was clean and friendly staff"
United States
Katina
$94 nightly
The price is $106
Jan 5 - Jan 6, 2026
Total with taxes and fees
Microtel Inn & Suites by Wyndham Walterboro

Quality Inn

2.5 star property
4.3 mi from Colleton Medical Center
7.6 out of 10, Good, (850)
"Comfy beds and clean room with frig and microwave!"
United States
Cynthia
$55 nightly
The price is $61
Dec 22 - Dec 23
Total with taxes and fees
Quality Inn

Rodeway Inn Walterboro I-95

2.0 star property
4 mi from Colleton Medical Center
7.0 out of 10, Good, (259)
"The AC worked hgreat, .my room was clean and the staff was friendly. "
United States
Tammy
$47 nightly
The price is $52
Dec 21 - Dec 22
Total with taxes and fees
Rodeway Inn Walterboro I-95

Days Inn by Wyndham Walterboro

2.0 star property
4.2 mi from Colleton Medical Center
7.2 out of 10, Good, (761)
"Welcoming front desk and friendly staff"
United States
Mounika
$64 nightly
The price is $71
Dec 8 - Dec 9
Total with taxes and fees
Days Inn by Wyndham Walterboro

Budgetel

2.0 star property
3.7 mi from Colleton Medical Center
3.6 out of 10, (5)
"There was bedbugs! Tim was very friendly though. "
United States
Abu
$70 nightly
The price is $78
Dec 7 - Dec 8
Total with taxes and fees
Budgetel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What's the area like around Colleton Medical Center?
Colleton Medical Center is located in Walterboro. This welcoming area is known for its array of dining options. You'll find 35 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Colleton Medical Center?
Comfort Inn & Suites Walterboro I-95 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 4.1 mi (6.6 km) from Colleton Medical Center. Other good choices within a few miles include Motel 6 Walterboro, SC and Microtel Inn & Suites by Wyndham Walterboro.
How many hotels will I be able to find close to Colleton Medical Center?
Expedia has 35 hotels and other accommodations a few miles from Colleton Medical Center.
If I need to cancel the hotel reservation for my stay near Colleton Medical Center, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view the best deals available near Colleton Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Colleton Medical Center?
To access more information about rescheduling or cancelling your stay near Colleton Medical Center, click here.