Commerce Vacations from $389

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The Latest Commerce vacation packages

Price found within the past 48 hours. Click for updated prices.
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

3 out of 5
Price was $526, price is now $389 per person
$389
per person
Apr 9 - Apr 15
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
9.6/10 Exceptional! (84 reviews)
Clean rooms, great value.

Reviewed on Nov 28, 2025

The Riverview

The Riverview

4 out of 5
Price was $652, price is now $551 per person
$551
per person
Apr 9 - Apr 15
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
9.4/10 Exceptional! (513 reviews)
Run very well—check in great

Reviewed on Mar 2, 2026

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
Price was $569, price is now $483 per person
$483
per person
Apr 9 - Apr 15
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
9.6/10 Exceptional! (1,004 reviews)
This was our first time staying at a Drury Hotel. The room was clean and comfortable! We missed the evening snack, but breakfast was awesome! So many options. Would definitely stay again!

Reviewed on Mar 4, 2026

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
Price was $543, price is now $462 per person
$462
per person
Apr 9 - Apr 15
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
9.4/10 Exceptional! (1,004 reviews)
Great as all Drury’s

Reviewed on Mar 4, 2026

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
Price was $460, price is now $397 per person
$397
per person
Apr 9 - Apr 15
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Cape Girardeau (CGI)
9.6/10 Exceptional! (1,004 reviews)
Stayed there for 10 years when we leave the Gulf to head home. Great place to stop. Meals for supper and breakfast.

Reviewed on Mar 4, 2026

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Commerce Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $113 total per night from Mar 9 to Mar 10
$113 total
Mar 9 - Mar 10
Total with taxes and fees
9.6/10 Exceptional! (1,013 reviews)
This was our first time staying at a Drury Hotel. The room was clean and comfortable! We missed the evening snack, but breakfast was awesome! So many options. Would definitely stay again!

Reviewed on Mar 4, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $103 total per night from Mar 12 to Mar 13
$103 total
Mar 12 - Mar 13
Total with taxes and fees
9.4/10 Exceptional! (516 reviews)
Run very well—check in great

Reviewed on Mar 2, 2026

The Riverview
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Mar 10 to Mar 11
$102 total
Mar 10 - Mar 11
Total with taxes and fees
9.4/10 Exceptional! (1,006 reviews)
Great as all Drury’s

Reviewed on Mar 4, 2026

Drury Inn & Suites Cape Girardeau
See all 75 properties in Commerce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Commerce Vacation Packages

Commerce Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Cape Girardeau Municipal Airport (CGI)
Top Sights
Isle Casino Cape Girardeau, Cape Rock Park and Fort D Historic Site

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Frequently asked questions

How much does a Commerce vacation package cost?
You'll find cheap prices from $389 on Expedia for your Commerce escape. However, a range of factors like the season, length of stay and your choice of hotel will influence how much your vacation to Commerce costs.
What are the cheapest months to go to Commerce?
You can usually find lower rates and better availability in January, October and December. Browse our cheap Commerce vacation packages and you could land some great off-season discounts.
How many days is enough for Commerce?
With a well-organized itinerary, you can easily tick off the top Commerce attractions in a few days. But if you prefer to discover hidden gems or go on day tours, consider booking your Commerce vacation for longer.
How to find the best Commerce package deals?
Start your search for a Commerce package deal by entering your preferred trip dates and destination under our "Packages" tab. Then add a few filters, like "Property type" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the ideal Commerce package deal straight away, just change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Commerce getaway off to a flying start.
Is it cheaper to book a Commerce vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging flights and accommodations individually. Better still, you can personalize your Commerce getaway to fit your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Commerce?
Score amazing discounts by booking your flights in advance with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Commerce escape.
Does Expedia offer Book Now, Pay Later Commerce vacation packages?
If you're like us, you love going away but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Commerce trip across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.