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Sep 19 - Sep 21

Vacation Homes in Defiance

Stunning 1890's Home - Sleeps 8!
Enjoy cooking in this well-lit kitchen with appliances and a spacious island.

Stunning 1890's Home - Sleeps 8!

10.0 out of 10, Exceptional, (67)
"Beautiful house and location."
$391 nightly
The price is $401
Aug 3 - Aug 4
Total includes taxes and fees
Stunning 1890's Home - Sleeps 8!
AK's STL Pearl Grey House - Game Room
Enjoy meals in this well-equipped kitchen with a central island, oven, and dining area with a view.

AK's STL Pearl Grey House - Game Room

9.4 out of 10, Exceptional, (6)
"Quiet neighborhood, comfortable house, well-stocked kitchen. We would stay here again."
$543 nightly
The price is $543
Aug 4 - Aug 5
Total includes taxes and fees
AK's STL Pearl Grey House - Game Room
Honky Tonk Hideaway
Relax on the patio surrounded by a serene natural landscape with a dining table and wicker seating.

Honky Tonk Hideaway

9.2 out of 10, Wonderful, (5)
"Great place to stay"
Honky Tonk Hideaway
Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic
Kitchen features white cabinetry, stainless steel appliances, and a window with a bamboo blind.

Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic

9.6 out of 10, Exceptional, (53)
"Lovely home within a neighborhood subdivision. Clean, beautifully decorated, plenty of bedrooms and bathroom for our group. Close to restaurants and shopping. "
$382 nightly
The price is $382
Jul 27 - Jul 28
Total includes taxes and fees
Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic
Stunning Lakeside Retreat at Innsbrook w/ Swing, Canoe and 3 Kayaks
Cozy cabin with a loft area, accessible via a stone pathway, surrounded by a wooden fence.

Stunning Lakeside Retreat at Innsbrook w/ Swing, Canoe and 3 Kayaks

10.0 out of 10, Exceptional, (52)
"We had a great time. The home was great for our group of 7.! "
Stunning Lakeside Retreat at Innsbrook w/ Swing, Canoe and 3 Kayaks
Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway
Enjoy a spacious living area with a dining table and chairs, a kitchen with modern appliances, and large windows.

Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway

9.6 out of 10, Exceptional, (44)
"This was our third stay in this house! It’s the perfect location for visiting our son who attends Lindenwood. Quiet neighborhood, great place to walk our fur baby, comfy beds and decorated so cute!"
$324 nightly
The price is $324
Jul 27 - Jul 28
Total includes taxes and fees
Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway
Residence on the Roundabout
Relax in this open-plan living space with a comfortable bed, glass-top coffee table, and wicker chairs.

Residence on the Roundabout

9.6 out of 10, Exceptional, (133)
"We had a nice stay in this cute home. St. Charles is a wonderful place to visit! "
Residence on the Roundabout
St. Charles 1860's Gem - Sleeps 6!
Enjoy cooking in this well-equipped kitchen with an oven, dishwasher, and sink.

St. Charles 1860's Gem - Sleeps 6!

9.8 out of 10, Exceptional, (110)
"Great time and nice and quiet :) "
$256 nightly
The price is $256
Jul 27 - Jul 28
Total includes taxes and fees
St. Charles 1860's Gem - Sleeps 6!
Charming 3BR/2BA home—peaceful country vibes, perfect for relaxing stays!
Relax in a spacious living area with a tufted sofa and ceiling fan, offering a comfortable seating space and a view of the outdoors.

Charming 3BR/2BA home—peaceful country vibes, perfect for relaxing stays!

6.8 out of 10, (3)
"The house was great and Nicole was a great host. "
Charming 3BR/2BA home—peaceful country vibes, perfect for relaxing stays!
Walk to St Charles Main St. Shops, Eateries & Bars!
Relax in a spacious room with a comfortable seating area, dining table, and floor lamp.

Walk to St Charles Main St. Shops, Eateries & Bars!

10.0 out of 10, Exceptional, (69)
"The house was just as described and the location is just a few blocks from the historic area."
Walk to St Charles Main St. Shops, Eateries & Bars!
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
Enjoy al fresco dining under the shade of red umbrellas in this charming outdoor space.

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

10.0 out of 10, Exceptional, (260)
"It was a wonderful getaway it was close to St Peter's Church and downtown."
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟
Enjoy cooking in this well-lit kitchen with a refrigerator, oven, and microwave.

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟

9.8 out of 10, Exceptional, (63)
"Had a great stay! Perfect place and super cute! Perfect distance from downtown st. Charles!! Will stay here again!!!!"
🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟
Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
Relax in this stylish living room with a beige sofa, coffee table, and floor lamp.

Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.

10.0 out of 10, Exceptional, (34)
"Very clean and had everything we needed. TV had a lot of options and overall was very cozy and comfortable. "
Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
Private St Peters Home Patio Pool Table
Enjoy a peaceful view of the backyard from the large window, featuring a potted plant and a lamp on the side table.

Private St Peters Home Patio Pool Table

10.0 out of 10, Exceptional, (23)
"Very nice house to stay, Highly recommend "
Private St Peters Home Patio Pool Table
Pet Friendly - Private Home - Fenced Yard
Enjoy cooking in the fully equipped kitchen with a stove and oven, and relax in the living area with a sofa and flat-screen TV.

Pet Friendly - Private Home - Fenced Yard

10.0 out of 10, Exceptional, (20)
"Great rental property that was perfect for our stay! The hosts thought of everything and the home was clean and well appointed. If we are in town again I would absolutely stay here again."
Pet Friendly - Private Home - Fenced Yard
TJ’s Country Getaway- Dog Friendly
Enjoy outdoor gatherings by the fire pit in this secluded, fenced area.

TJ’s Country Getaway- Dog Friendly

10.0 out of 10, Exceptional, (41)
"It had everything you need for a relaxing stay. "
$133 nightly
The price is $133
Jul 31 - Aug 1
Total includes taxes and fees
TJ’s Country Getaway- Dog Friendly
Washington Guest House
Enjoy casual dining at the central island with bar stools, offering a view of the outdoors.

Washington Guest House

10.0 out of 10, Exceptional, (35)
"Wonderful weekend. House was comfy even with single digit temperatures outside. Very clean and well stocked. Enough room for the six of us to play games, cook and eat as well as spread out and make hand knitted blankets. Several fun things in house that allows you a peek into the personality of the owners. Thank you for sharing your house with us. "
$332 nightly
The price is $372
Jul 28 - Jul 29
Total includes taxes and fees
Washington Guest House
Judge’s Quarters: Exquisite Luxury Apartment
Enjoy al fresco dining on the patio with a stainless steel grill and comfortable seating for two.

Judge’s Quarters: Exquisite Luxury Apartment

10.0 out of 10, Exceptional, (22)
"Perfect stay for the weekend! It was cozy and I was able to walk all around town from the apartment. Everything was just perfect!"
Judge’s Quarters: Exquisite Luxury Apartment
Hilltop Hideaway with Lake Front Access
Relax by the pool surrounded by trees, with a covered pavilion offering shade and a ceiling fan.

Hilltop Hideaway with Lake Front Access

Hilltop Hideaway with Lake Front Access
Luxe Innsbrook Resort Home - Lakes/Golf/Trails
Relax and socialize in this sheltered outdoor space with a comfortable L-shaped sofa set and ceiling fan.

Luxe Innsbrook Resort Home - Lakes/Golf/Trails

9.6 out of 10, Exceptional, (17)
"House was very large and accommodated our group of 10 very well. The house had everything we needed during our stay. Access to the community pool was also nice. We would return again."
Luxe Innsbrook Resort Home - Lakes/Golf/Trails
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Elimwood Hotel, A Ramada by Wyndham

Elimwood Hotel, A Ramada by Wyndham

10/10 Excellent
"Great value - quiet area near the Casino. Staff was very friendly. Some of the appliances could use a refresh. But service was great!!"
Kunal 3-night trip
Posted 1 day ago
Elimwood Hotel, A Ramada by Wyndham