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Our top choices for Defiance vacation homes

TJ’s Country Getaway- Dog Friendly

TJ’s Country Getaway- Dog Friendly
Union
10.0 out of 10, Exceptional, (45)
"My dog and I stayed for the week while attending our National Specialty at Purina Farms. I would definitely stay here again. Safe, quiet, peaceful and tons of amenities. 10/10!"
United States
Laura S.
TJ’s Country Getaway- Dog Friendly

Cozy 3 Bedroom/ Family Comfort & Convenient Location

Cozy 3 Bedroom/ Family Comfort & Convenient Location
2.0 star property
Wentzville
10.0 out of 10, Exceptional, (1)
"We had a wonderful stay! The home was very clean, check-in was super easy, and it was the perfect place for our family. Everything was exactly as described and we felt comfortable the entire time. Would definitely stay here again!"
United States
Tricia W.
Cozy 3 Bedroom/ Family Comfort & Convenient Location

Two King and Two Twin Beds in the Heart of French Town

Two King and Two Twin Beds in the Heart of French Town
2.0 star property
St. Charles Historic District
10.0 out of 10, Exceptional, (1)
"Cute house and great location! "
United States
Courtney A.
Two King and Two Twin Beds in the Heart of French Town

The Below Deck Suite

The Below Deck Suite
Saint Charles
9.0 out of 10, Wonderful, (2)
"Overall good place for a family. The neighborhood is quiet and there is a good amount of space. Easy to find and to get places. You will hear the people upstairs and one bed was very squeaky. It was very clean and the couches are very comfy. "
United States
Amy B.
The Below Deck Suite

5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1

5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
St. Charles Historic District
9.2 out of 10, Wonderful, (12)
"House was beautiful. Very nice quiet stay"
United States
Amy S.
5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1

Adorable 2 King Bed Frenchtown Home

Adorable 2 King Bed Frenchtown Home
2.0 star property
Saint Charles
Adorable 2 King Bed Frenchtown Home

Cozy little house blocks from the Park & Fair Grounds. EV Charger equipped.

Cozy little house blocks from the Park & Fair Grounds. EV Charger equipped.
Washington
10.0 out of 10, Exceptional, (58)
"Had a great stay. Great location, clean, friendly host. "
United States
Orrin P.
Cozy little house blocks from the Park & Fair Grounds. EV Charger equipped.

Quaint and Cozy Hamlet

Quaint and Cozy Hamlet
O'Fallon
9.6 out of 10, Exceptional, (12)
"Overall great time- communication was wonderful with Kevin, neighborhood was quiet, perfect for our stay. The house wasn’t as clean as I’d expect but besides that, great stay!"
United States
Madison A.
Quaint and Cozy Hamlet

1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
8.4 out of 10, Very Good, (7)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
1st Capitol Mansion - Suite 401

Wine Country Getaway | JZ Vacation Rentals

Wine Country Getaway | JZ Vacation Rentals
3.5 star property
Washington
8.0 out of 10, Very Good, (1)
"Great communication, had a couple of leaks and shower flooded but the maintenance came right away to fix it. Overall clean, AC/Heat unit in each room, big kitchen, wonderful sitting area and decor."
United States
Stacy
Wine Country Getaway | JZ Vacation Rentals

Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill

Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill
2.0 star property
Byrnes Mill
10.0 out of 10, Exceptional, (11)
"Great place to stay. Huge fenced in backyard for dogs to run around. Host was real helpful with any questions we had"
United States
Michael A.
Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill

Madison House 1 -Walk to Main St

Madison House 1 -Walk to Main St
St. Charles Historic District
8.6 out of 10, Excellent, (14)
"The house was clean and well stocked, location was great, and plenty of street parking. "
United States
Brad K.
Madison House 1 -Walk to Main St

Pet and kid friendly duplex with 2 bedrooms

Pet and kid friendly duplex with 2 bedrooms
Pacific
9.6 out of 10, Exceptional, (47)
"Such a charming house. Very clean with great amenities. "
United States
Darla M.
Pet and kid friendly duplex with 2 bedrooms

Cozy Historic WashMo home

Cozy Historic WashMo home
Washington
9.2 out of 10, Wonderful, (27)
"Great location and easy to work with host"
United States
melissa G.
Cozy Historic WashMo home

The Olive House - Near Main Street- Fully rehabbed

The Olive House - Near Main Street- Fully rehabbed
Saint Charles
8.6 out of 10, Excellent, (8)
"Perfect location for buddies golf trip... clean comfortable house...very helpful host!"
United States
Mark H.
The Olive House - Near Main Street- Fully rehabbed

Spacious Townhome Retreat by StayLage

Spacious Townhome Retreat by StayLage
O Fallon
9.8 out of 10, Exceptional, (9)
"This was the perfect place for us and our adult daughter while we were in town for our sons wedding."
United States
Tanya h.
Spacious Townhome Retreat by StayLage

Kid and pet friendly 2 nd floor duplex

Kid and pet friendly 2 nd floor duplex
Pacific
9.0 out of 10, Wonderful, (28)
"We had a great time. We will definately be back! "
United States
Shayla Y.
Kid and pet friendly 2 nd floor duplex

Honky Tonk Hideaway

Honky Tonk Hideaway
St. Charles Historic District
8.8 out of 10, Excellent, (12)
"Great location close to historic district."
United States
Hugh S.
Honky Tonk Hideaway

Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway

Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway
St. Charles Historic District
9.6 out of 10, Exceptional, (58)
"Nice property. Clean. "
United States
Belinda J.
Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway

St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!
St. Charles Historic District
9.8 out of 10, Exceptional, (134)
"This was such a cute historical home and was perfect for our weekend in St Charles!"
United States
Isabelle C.
St. Charles 1860's Gem - Sleeps 6!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Vacation Homes information

Number of reviews
473
Accommodation
269 Vacation Homes
Lowest Price
Highest Price

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