Cheap Flights to Santa Cruz from $217

View $217 flight on Fri, Mar 13, 2026Opens in a new window

Popular airlines to Santa Cruz

  • Avianca

  • LATAM Airlines Group

  • Copa

  • Boliviana De Aviacion

  • United

  • Air Europa

  • Iberia

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

How much is the cheapest flight to Santa Cruz?

Prices were available within the past 7 days and start at $217 for one-way flights and $482 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, Mar 13 - Mon, Mar 16
MIA
Miami
VVI
Santa Cruz
$482 Roundtrip, just found
$482
Roundtrip
just found
Select Copa flight, departing Fri, Mar 13 from Miami to Santa Cruz, returning Mon, Mar 16, priced at $482 just found
Copa
Fri, Mar 13 - Mon, Mar 16
MIA
Miami
VVI
Santa Cruz
$492 Roundtrip, just found
$492
Roundtrip
just found
Select Copa flight, departing Fri, Mar 13 from Miami to Santa Cruz, returning Mon, Mar 16, priced at $492 just found
Copa
Thu, Apr 23 - Wed, Apr 29
MIA
Miami
VVI
Santa Cruz
$501 Roundtrip, just found
$501
Roundtrip
just found
Select Copa flight, departing Thu, Apr 23 from Miami to Santa Cruz, returning Wed, Apr 29, priced at $501 just found
Copa
Thu, Mar 19 - Mon, Apr 13
MIA
Miami
VVI
Santa Cruz
$502 Roundtrip, found 16 hours ago
$502
Roundtrip
found 16 hours ago
Select Copa flight, departing Thu, Mar 19 from Miami to Santa Cruz, returning Mon, Apr 13, priced at $502 found 16 hours ago
Copa
Thu, Mar 19 - Mon, Apr 13
MIA
Miami
VVI
Santa Cruz
$512 Roundtrip, found 16 hours ago
$512
Roundtrip
found 16 hours ago
Select Copa flight, departing Thu, Mar 19 from Miami to Santa Cruz, returning Mon, Apr 13, priced at $512 found 16 hours ago
Copa
Thu, Apr 23 - Wed, Apr 29
MIA
Miami
VVI
Santa Cruz
$517 Roundtrip, just found
$517
Roundtrip
just found
Select Copa flight, departing Thu, Apr 23 from Miami to Santa Cruz, returning Wed, Apr 29, priced at $517 just found
avianca
Wed, Mar 18 - Sun, Apr 12
MIA
Miami
VVI
Santa Cruz
$520 Roundtrip, found 1 day ago
$520
Roundtrip
found 1 day ago
Select avianca flight, departing Wed, Mar 18 from Miami to Santa Cruz, returning Sun, Apr 12, priced at $520 found 1 day ago
LATAM Airlines Group
Fri, May 29 - Sat, Jun 6
MIA
Miami
VVI
Santa Cruz
$566 Roundtrip, found 1 hour ago
$566
Roundtrip
found 1 hour ago
Select LATAM Airlines Group flight, departing Fri, May 29 from Miami to Santa Cruz, returning Sat, Jun 6, priced at $566 found 1 hour ago
United
Sun, Mar 29 - Tue, Mar 31
EWR
New York
VVI
Santa Cruz
$603 Roundtrip, found 3 days ago
$603
Roundtrip
found 3 days ago
Select United flight, departing Sun, Mar 29 from New York to Santa Cruz, returning Tue, Mar 31, priced at $603 found 3 days ago
Boliviana De Aviacion
Fri, Mar 13 - Mon, Mar 16
MIA
Miami
VVI
Santa Cruz
$652 Roundtrip, just found
$652
Roundtrip
just found
Select Boliviana De Aviacion flight, departing Fri, Mar 13 from Miami to Santa Cruz, returning Mon, Mar 16, priced at $652 just found

Enjoy extra legroom, flight flexibility, and a seamless travel experience.

*Flight schedules are subject to change.

*Flight schedules are subject to change.

Trending flights to Santa Cruz

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, Mar 13 - Mon, Mar 16
MIA
Miami
VVI
Santa Cruz
$482 Roundtrip, just found
$482
Roundtrip
just found
Select Copa flight, departing Fri, Mar 13 from Miami to Santa Cruz, returning Mon, Mar 16, priced at $482 just found
*Available to One Key members.