Santa Cruz Vacation Packages 2026

Your Santa Cruz Vacation

With a Santa Cruz vacation package, you can forget about planning hassles and simply focus on experiencing everything this thrilling destination has to offer. The best way to plan your trip to Santa Cruz is to begin with its most popular cities, which include Samaipata, Roboré and Camiri. Expedia is a one-stop shop when it comes to planning your Santa Cruz vacation. From flights and hotels, to activities and more, we're here to help you create a travel experience like no other.

Top destinations in Santa Cruz

A colonial-style building with a bell tower, palm trees, and a paved walkway.

A mountainous landscape with rugged peaks and lush green valleys.

A person wearing a yellow and black costume with a headpiece.

A corridor with arches and detailed wall carvings.

A historic building with intricate architectural details and a clock tower.

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most.Learn more about Santa Cruz

Equipetrol

Though Equipetrol might not have many top sights, you can venture to the surrounding area to see attractions like Santa Cruz Zoo and Municipal Library.

Find hotel + flight trips in Equipetrol

Centro Histórico

If you're spending some time in Centro Histórico, Plaza 24 de Septiembre and La Recova Artisan Walk are top sights worth seeing.

Find hotel + flight trips in Centro Histórico

Hamacas

While Hamacas isn't home to many top sights, Las Brisas Shopping Center and Santa Cruz Zoo are some notable places to visit nearby.

Find hotel + flight trips in Hamacas

Zona Sur (South Zone)

Zona Sur (South Zone) might not have many top sights, but Ramon Tahuichi Aguilera Stadium and Plaza 24 de Septiembre are two attractions nearby that you can check out.

Find hotel + flight trips in Zona Sur (South Zone)

Urubó

While Urubó might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Guembe Biocenter and Ventura Mall.

Find hotel + flight trips in Urubó

Best Places to Vacation in Santa Cruz

1. Plan your dream getaway to Santa Cruz

Santa Cruz, located in Bolivia, offers a unique and vibrant atmosphere for city vacationers. With its diverse range of attractions, including shopping centers, charming cafes, colorful flower markets, a zoo, and various excursions, visitors can immerse themselves in the local culture. The city also boasts a beautiful cathedral and is a haven for birdwatching enthusiasts. For those interested in sports, Santa Cruz is known for its passion for soccer. Additionally, the city has a thriving business scene and offers a wide selection of local beers to enjoy. Overall, Santa Cruz provides a delightful and exciting experience for travelers.

The peak season is from July to September
The off-peak season is from October to December
Travelers tend to stay 4 days in Santa Cruz

2. Escape to Samaipata with a vacation package

Samaipata, located in Santa Cruz, Bolivia, offers a unique outdoor vacation experience. With its diverse geography, this destination is perfect for activities such as hiking, mountain exploration, forest and jungle adventures, camping, and waterfall visits. Wildlife enthusiasts will also enjoy the opportunity for birdwatching and spotting local fauna. Samaipata is also home to an impressive UNESCO World Heritage Site and a zoo. Popular traveler activities include destination activities, tours, and sightseeing. Immerse yourself in the natural beauty and vibrant atmosphere of Samaipata for an unforgettable outdoor vacation.

The peak season is from December to February
The off-peak season is from October to December
Travelers tend to stay 2 days in Samaipata

3. Experience Warnes with a travel package

Warnes, Santa Cruz, Bolivia offers a unique and memorable family vacation experience. The local atmosphere is warm and welcoming, with friendly locals eager to share their culture and traditions. The town is surrounded by beautiful natural landscapes, including lush forests and picturesque mountains, perfect for outdoor activities such as hiking and exploring. Families can also visit local attractions like the Warnes Zoo, which houses a variety of exotic animals, or enjoy traditional Bolivian cuisine at the town's charming restaurants. With its rich history and natural beauty, Warnes is an ideal destination for a family vacation.

The peak season is from September to November
The off-peak season is from March to May

4. Create memories in San Jose de Chiquitos with a vacation package

San Jose de Chiquitos in Santa Cruz, Bolivia, offers a unique cultural vacation experience. With its sunny weather, lush forests, and stunning natural parks, the town is a haven for nature lovers. Explore the historical urban center and marvel at the beautiful cathedral, a true architectural gem. Immerse yourself in the local culture by visiting the various churches and experiencing their rich traditions. The scenery in San Jose de Chiquitos is breathtaking, with picturesque landscapes and vibrant colors. Whether you're seeking a peaceful retreat or an adventure-filled getaway, this charming town has it all.

The peak season is from July to September
The off-peak season is from October to December
Travelers tend to stay 2 days in San Jose de Chiquitos

6. Explore Roboré with a vacation package

Concepcion, Santa Cruz, Bolivia, offers a rich cultural experience for travelers. The town is known for its churches, waterfalls, cathedral, and natural beauty. Visitors can explore the picturesque lake, enjoy live music performances, and immerse themselves in local festivals. Concepcion also boasts a vibrant theater scene and opportunities to appreciate art in museums. Whether you're seeking a peaceful retreat in nature or a lively cultural experience, Concepcion has something to offer. With its unique blend of tradition and modernity, this Bolivian town promises an unforgettable vacation for culture enthusiasts.

The peak season is from December to February
The off-peak season is from September to November

5. Discover Concepcion with our vacation deals

Roboré, located in Santa Cruz, Bolivia, offers a unique cultural vacation experience. Immerse yourself in the vibrant local atmosphere as you explore the town's rich heritage and traditions. Discover the region's indigenous culture through captivating art, music, and dance performances. Indulge in the local cuisine, savoring traditional Bolivian dishes bursting with flavors. Engage with friendly locals and learn about their customs and way of life. Explore the breathtaking natural landscapes surrounding Roboré, from lush rainforests to majestic waterfalls. Whether you're wandering through charming local markets or exploring ancient ruins, Roboré promises an unforgettable cultural adventure.

The peak season is from October to December
The off-peak season is from May to July

Things to do in Santa Cruz

Santa Cruz offers a vibrant mix of culture and family-friendly activities, perfect for a city-themed getaway. Enjoy shopping at local centers and malls, relax at resorts, and explore outdoor adventures. Don't miss out on day trips and wine tastings to experience the region's unique flavors. Whether you’re looking for a beach vacation or engaging activities, Santa Cruz has something for everyone to enjoy.

Shopping

Ventura Mall offers a vibrant shopping experience with entertainment and family-friendly options. For unique crafts, visit La Recova Artisan Walk, where local artisans showcase their work. Finally, explore Patio Design LifeStyle Center for a mix of shopping and dining in a lively atmosphere.

Recreation

Experience the vibrant energy at the Ramon Tahuichi Aguilera Stadium, perfect for sports enthusiasts. Enjoy cinematic adventures at Cine Center, ideal for family outings and romantic dates. Immerse yourself in culture at Casa Municipal de Cultura Raúl Otero Reiche, where entertainment and family vibes come alive.

Adventure

Parque Nacional Amboró offers breathtaking hiking trails through diverse ecosystems, where you can spot exotic wildlife. For thrill-seekers, the nearby Lomas de Arena invites you to explore stunning sand dunes, perfect for sandboarding and adrenaline-filled adventures amidst striking landscapes.

Nightlife

In Santa Cruz, dive into vibrant nightlife at Avenida San Martín and Equipetrol, where lively bars and dance clubs come alive. Enjoy live music and local DJs, or relax at rooftop lounges with stunning views. Don’t miss the energetic atmosphere that keeps the city buzzing until dawn.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, offers a delightful blend of culture and adventure, making it perfect for family vacations and city explorations. Key attractions include national parks, impressive cathedrals, and historic landmarks. Visitors can enjoy outdoor activities and cultural experiences, with nearby points of interest like Santa Barbara and the scenic Santa Cruz Beach enhancing your trip. Whether seeking adventure or cultural immersion, Santa Cruz has something for everyone.

Plaza 24 de Septiembre: This vibrant square serves as the heart of Santa Cruz, surrounded by historical architecture and lively cafes. It's a perfect spot to immerse yourself in local culture, enjoy street performances, and savor Bolivian cuisine while soaking up the bustling city vibes.
Amboró National Park: A paradise for adventure seekers, this national park boasts diverse ecosystems and stunning landscapes. Hike through lush forests, encounter unique wildlife, and revel in the breathtaking views, making it an ideal destination for outdoor enthusiasts and nature lovers.
San Lorenzo Cathedral: A stunning example of colonial architecture, this cathedral reflects the rich cultural heritage of Santa Cruz. Its intricate design and serene atmosphere make it a perfect place for reflection and appreciation of local artistry.

Best time to go to Santa Cruz

The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in October, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Santa Cruz falls in June, visitor numbers are average and weather is mostly sunny with light rain.

Calendar Month	Temperature	Precipitation	Cloudiness	Occupancy	Pricing
January	78.3°F (25.700000000000003°C)	Light Rain	Mostly Sunny	Slightly Low	Average
February	77.0°F (25.0°C)	Light Rain	Mostly Cloudy	Slightly High	Average
March	76.5°F (24.700000000000003°C)	Light Rain	Mostly Sunny	Average	Slightly High
April	74.5°F (23.6°C)	Light Rain	Mostly Sunny	Average	Slightly High
May	70.2°F (21.200000000000003°C)	Light Rain	Mostly Sunny	Slightly Low	Average
June	67.8°F (19.9°C)	Light Rain	Mostly Sunny	Average	Slightly Low
July	68.5°F (20.3°C)	No Rain	Mostly Sunny	Average	Average
August	72.9°F (22.700000000000003°C)	No Rain	Sunny	Slightly High	Slightly Low
September	77.9°F (25.5°C)	Light Rain	Sunny	Slightly High	Slightly High
October	79.5°F (26.4°C)	Light Rain	Mostly Sunny	Average	Average
November	79.3°F (26.3°C)	Light Rain	Mostly Sunny	Average	Slightly Low
December	78.4°F (25.8°C)	Light Rain	Mostly Sunny	Slightly Low	Average

Tips to save on your trip to Santa Cruz

Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Santa Cruz.
Consider traveling to Santa Cruz during the low season (June, August and November) for more affordable options.
Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Find the Best Santa Cruz Vacation Packages

Santa Cruz Essential Information

Language	Spanish
Currency	Bolivian bolivianos
Local Welcome	¡Hola!
Local Goodbye	Adiós
Closest Airport	Viru Viru Intl. Airport (VVI)
Top Sights	Santa Cruz Zoo, Amboró National Park and Municipal Botanical Garden of Santa Cruz

Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra

AVENIDA CRISTOBAL DE MENDOZA Santa Cruz

$40 nightly

$40 total

Oct 25 - Oct 26

9.4/10 Exceptional! (153 reviews)

"The hotel is OK, but nothing more. Stuff was unpleasant"

Reviewed on Sep 24, 2026

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ave. San Martin, #455 Santa Cruz

$135 nightly

$135 total

Nov 7 - Nov 8

Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23 Santa Cruz Santa Cruz

$106 nightly

$106 total

Nov 1 - Nov 2

See all 343 properties in Santa Cruz

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz vacation package cost?

Vacation packages in Santa Cruz, Bolivia are centered on Santa Cruz city. A week-long trip there typically costs around $1,350 per adult, with prices ranging from around $550 to $2,050 per adult.*Package prices shown are the average total cost per adult across Expedia bookings over the past year and may change depending on availability, dates, and demand.

How can I save money on a Santa Cruz vacation package?

When you bundle, you can save up to 30%*. To save money on a Santa Cruz package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.

What's included in a Santa Cruz vacation package?

A Santa Cruz vacation package in Santa Cruz lets you combine flights, hotel stays, and rental cars. Many hotels offer airport shuttle service to Santa Cruz (VVI-Viru Viru Intl.), and most hotels provide free breakfast.Exactly what's included will vary by hotel and package, so it's worth reviewing the details before you confirm your booking.

How do I find cheap Santa Cruz vacation package deals?

Santa Cruz vacation packages are available in Santa Cruz, where prices start around $190 per adult for weekend trips.Bundling your flight and hotel can offer additional savings compared with booking separately. Week-long Santa Cruz packages typically save around $40 per adult, and weekend trips can save around $15 per adult.Browse cheap vacation packages in Santa Cruz on Expedia to compare current deals.*Package prices shown are the average total cost per adult across Expedia bookings over the past year and may change depending on availability, dates, and demand.

What is the best time to visit Santa Cruz?

The best time for a Santa Cruz vacation package in Santa Cruz city is typically March, May, and July, which are the peak booking months. In March, average temperatures are around 76°F with highs of 85°F, while May sees average temperatures of 70°F with highs of 78°F. Timing reflects Santa Cruz city specifically, so conditions may differ elsewhere in the region.If you'd prefer a quieter trip with fewer visitors, consider traveling in January or October. January offers average temperatures of 78°F with highs of 87°F, and October is slightly warmer with average temperatures of 80°F and highs of 89°F.

What types of vacation packages are available in Santa Cruz?

Vacation packages in Santa Cruz, concentrated in the city of Santa Cruz, come in several styles:

For breakfast-inclusive stays: Surbackpackers, rated 9.5 out of 10 by travelers, offers complimentary breakfast and free WiFi.
For budget-friendly options: The 4.5-star Gran Hotel Santa Cruz provides family rooms, an outdoor pool, and free breakfast, making it a good value choice.
For couples: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, a 3.5-star property rated 8.9 out of 10 by travelers, features a hot tub and outdoor pool. Guests often highlight its excellent location and friendly staff.
For families: The 4.5-star Camino Real Hotel, rated 8.8 out of 10 by travelers, includes family rooms and an indoor pool. Travelers frequently praise the super helpful staff and nice pool.

Which destinations should I consider for a Santa Cruz vacation?

For a Santa Cruz vacation, the region offers several distinct areas to consider as your base, each catering to different travel styles:

Santa Cruz: This city is the main base for travelers seeking city and urban attractions, cultural experiences and is well-suited for business travel or family-friendly trips.
Samaipata: For those interested in cultural attractions combined with outdoor activities and scenic views, Samaipata offers an adventure-focused stay.
Cuevas: Couples looking for a romantic getaway with opportunities for outdoor activities and scenic views will find Cuevas to be a fitting choice.
Warnes: Ideal for families, Warnes provides a mix of family-friendly attractions, outdoor activities, and urban conveniences.

Is Santa Cruz better suited for a beach vacation or a cultural trip?

Santa Cruz, Bolivia is primarily a cultural and urban destination, known for its rich heritage and city attractions. Travelers seeking a Santa Cruz vacation will find plenty to explore, from historic landmarks to vibrant city life.The city of Santa Cruz offers a wealth of cultural experiences, including the central Plaza 24 de Septiembre and the impressive San Lorenzo Cathedral.

Which airport should I use for a Santa Cruz vacation?

For a Santa Cruz vacation, the primary gateway is Santa Cruz (VVI-Viru Viru Intl.) Airport, which serves the region. Another option within the city is Santa Cruz (SRZ-El Trompillo) Airport. Both airports provide access to the city of Santa Cruz and the wider region, with onward travel available to your chosen base.

What are the top things to do in Santa Cruz?

A Santa Cruz vacation in Bolivia is best explored from the city of Santa Cruz, which serves as a vibrant base for cultural and urban attractions. From here, you can discover a range of sights both within the city and in the surrounding region:Browse and book things to do in Santa Cruz on Expedia.

What is the best time to book a Santa Cruz vacation package?

Book your Santa Cruz vacation package around 2 weeks in advance, with packages located in Santa Cruz. It gives you time to secure your preferred flights and hotel while rates are still competitive. Most travelers book between 1 and 6 weeks out.March, May, and July are the most popular months for Santa Cruz packages in Santa Cruz, so booking earlier is advisable if you're traveling during those months.

How many days do you need for a Santa Cruz vacation?

Most Santa Cruz vacation packages last around 5 days, with stays in Santa Cruz, a central urban destination known for its cultural attractions. Week-long trips are popular, and weekend getaways are also common, giving you ample time to explore sights like Plaza 24 de Septiembre.

Can I change or cancel my Santa Cruz vacation package if my plans change?

Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.

Do One Key members get extra savings when booking Santa Cruz vacation packages?

Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.

Does Expedia offer Book Now, Pay Later Santa Cruz vacation packages?

Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Santa Cruz vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.

How do I find last-minute vacation packages to Santa Cruz?

To find last-minute vacation packages to Santa Cruz, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.

How does free cancellation work on Santa Cruz vacation packages?

Free cancellation on a Santa Cruz vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.

Is it cheaper to book a Santa Cruz vacation as a package or separately?

Booking flights and hotels together can unlock lower overall prices. Better still, you can tailor your Santa Cruz getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.

Why should I book my Santa Cruz vacation package with Expedia?

Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.

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A historic tower with a clock, surrounded by lush greenery and palm trees.

San Lorenzo Cathedral

9.0/10 (84 reviews)

One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork.

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Ventura Mall

9.0/10 (183 reviews)

During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.

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Guembe Biocenter

8.8/10 (60 reviews)

Explore the great outdoors at Guembe Biocenter, a lovely green space in Colinas del Urubo. While in the area, you can find time to visit its shops.

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Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)

Catch an event at Ramon Tahuichi Aguilera Stadium during your trip to Santa Cruz. While in the area, you can find time to visit its shops.

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Las Brisas Shopping Center

8.4/10 (40 reviews)

You can find the perfect gifts to bring home at Las Brisas Shopping Center during your visit to Santa Cruz. While in the area, you can find time to visit its shops.

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Santa Cruz Zoo

8.4/10 (53 reviews)

Why not visit the native and exotic animals who call Santa Cruz Zoo home during your vacation in Santa Cruz? While in the area, you can find time to visit its shops.

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What to do in Santa Cruz

Historical Tour: Visit to the Che Mausoleum in Vallegrande

Historical Tour in Vallegrande: Che's Mausoleum and Laundry

$19

per adult

Vallegrande City Tour: History, Culture, and Flavor

$29

per adult

Common grave, where the body of Che Guevara was found in 1997.

CITY TOURS RUTA DEL CHE: Walking Tour Real Scenarios

$10

per adult

See all activities in Santa Cruz

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Other vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

Santa Cruz Vacations & Trips

Book a Hotel + Flight or Car together to unlock savings

Your Santa Cruz Vacation

Top destinations in Santa Cruz

Santa Cruz

Samaipata

Warnes

San Jose de Chiquitos

Concepcion

Where to stay in Santa Cruz

Equipetrol

Centro Histórico

Hamacas

Zona Sur (South Zone)

Urubó

Best Places to Vacation in Santa Cruz

1. Plan your dream getaway to Santa Cruz

2. Escape to Samaipata with a vacation package

3. Experience Warnes with a travel package

4. Create memories in San Jose de Chiquitos with a vacation package

6. Explore Roboré with a vacation package

5. Discover Concepcion with our vacation deals

Things to do in Santa Cruz

Find the best attractions in Santa Cruz

Best time to go to Santa Cruz

Tips to save on your trip to Santa Cruz

Find the Best Santa Cruz Vacation Packages

Santa Cruz Essential Information

Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Marriott Santa Cruz de la Sierra Hotel

Frequently asked questions

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre

San Lorenzo Cathedral

Ventura Mall

Guembe Biocenter

Ramon Tahuichi Aguilera Stadium

Las Brisas Shopping Center

Santa Cruz Zoo

What to do in Santa Cruz

Historical Tour in Vallegrande: Che's Mausoleum and Laundry

Vallegrande City Tour: History, Culture, and Flavor

CITY TOURS RUTA DEL CHE: Walking Tour Real Scenarios

Other vacations you might like

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