Downtown West Vacations from $279

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Your Downtown West Vacation

Downtown West is beckoning! Whatever type of getaway you're organizing, you can experience and see more of this neighborhood with a Downtown West vacation package. Your trip to Downtown West wouldn't be complete without exploring popular attractions nearby such as Busch Stadium, Gateway Arch and Dome at America’s Center. Whatever your travel goals or budget, booking a perfect Downtown West vacation is easy with Expedia.

The Latest Downtown West Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG

3 out of 5
Price was $380, price is now $279 per person
$279
per person
Oct 2 - Oct 5
found 11 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.4/10 Very Good! (371 reviews)
Very nice and helpful staff all the time

Reviewed on Aug 7, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $768, price is now $407 per person
$407
per person
Oct 2 - Oct 5
found 11 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
9.2/10 Wonderful! (1,562 reviews)
Always comfortable, always convenient and reliable when I'm visiting the area. It's my go-to hotel in the area.

Reviewed on Aug 25, 2025

Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Save 100% on your flight
Price was $396, price is now $279 per person
$279
per person
Oct 2 - Oct 5
found 12 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.2/10 Very Good! (763 reviews)
I booked online and paid via the app. When I arrived on site they explained they had overbooked and had no rooms available. The staff was amazing and went above and beyond and secured a room at another location. Thank you to the staff for taking care of us.

Reviewed on Jul 26, 2025

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $527, price is now $381 per person
$381
per person
Oct 22 - Oct 25
found 19 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
8.6/10 Excellent! (1,006 reviews)
The Cheshire kept well from of old! We felt back in to the ages yet very 21C amenities. The location is perfect to explore St. Louis. We'd like to come back!

Reviewed on Aug 23, 2025

DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

4 out of 5
Save 100% on your flight
Price was $484, price is now $352 per person
$352
per person
Oct 2 - Oct 5
found 11 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.6/10 Excellent! (1,000 reviews)
Beautiful property, pleasant and responsive staff, delicious warm cookies! And convenient location near city hall and police department.

Reviewed on Jul 27, 2025

Where to stay in Downtown West

Find the best Downtown West areas and neighborhoods for the activities you enjoy most. Learn more about Downtown West
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

Downtown West Hotel Deals

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $116 total per night from Sep 3 to Sep 4
$116 total
Sep 3 - Sep 4
Total with taxes and fees
8.8/10 Excellent! (1,588 reviews)
"The evening snacks and drinks were a great little bonus"

Reviewed on Aug 25, 2025

Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Sep 1 to Sep 2
$173 total
Sep 1 - Sep 2
Total with taxes and fees
21C Museum Hotel St Louis
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $132 total per night from Sep 3 to Sep 4
$132 total
Sep 3 - Sep 4
Total with taxes and fees
Drury Inn & Suites St. Louis Union Station
See all 1,747 properties in Downtown West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Downtown West

St. Louis Union Station

St. Louis Union Station

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

St. Louis Union Station
City Museum featuring a city as well as children

City Museum

This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.

City Museum
Washington Avenue Historic District

Washington Avenue Historic District

Food, fashion and the blues reign supreme in this creative district of downtown St. Louis. Wander elegant tree-lined streets and delve into city history at museums.

Washington Avenue Historic District

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

$32
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

$169
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
Step into the shadows and discover the haunting tales of our city's past.

St. Louis Ghosts: Gateway Ghouls and Hauntings

$26
per adult
100% of travellers recommend
St. Louis Ghosts: Gateway Ghouls and Hauntings
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.