Downtown West Vacations from $348

Book a Hotel + Flight or Car together to unlock savings

Photo by Terry Eaves

Your Downtown West Vacation

Downtown West is beckoning! Whatever type of getaway you're organizing, you can experience and see more of this neighborhood with a Downtown West vacation package. Your trip to Downtown West wouldn't be complete without exploring popular attractions nearby such as Busch Stadium, Gateway Arch and Dome at America’s Center. Whatever your travel goals or budget, booking a perfect Downtown West vacation is easy with Expedia.

The Latest Downtown West Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
Ameristar Casino Resort and Spa
Marriott St. Louis Airport
Moonrise Hotel
Landing Furnished Apartments - Central West End

Where to stay in Downtown West

Find the best Downtown West areas and neighborhoods for the activities you enjoy most. Learn more about Downtown West

Downtown West Hotel Deals

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $122 total per night from Nov 22 to Nov 23
$122 total
Nov 22 - Nov 23
Total with taxes and fees
Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Dec 6 to Dec 7
$173 total
Dec 6 - Dec 7
Total with taxes and fees
21C Museum Hotel St Louis
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $134 total per night from Nov 22 to Nov 23
$134 total
Nov 22 - Nov 23
Total with taxes and fees
9.4/10 Exceptional! (1,620 reviews)
"Great overnight stay to celebrate Veterans Day"

Reviewed on Nov 12, 2026

Drury Plaza Hotel St. Louis Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Downtown West attractions

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.