Downtown West Vacations from $209

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Your Downtown West Vacation

Downtown West is beckoning! Whatever type of getaway you're organizing, you can experience and see more of this neighborhood with a Downtown West vacation package. Your trip to Downtown West wouldn't be complete without exploring popular attractions nearby such as Busch Stadium, Gateway Arch and Dome at America’s Center. Whatever your travel goals or budget, booking a perfect Downtown West vacation is easy with Expedia.

The Latest Downtown West Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Riverport
Save 100% on your flight
$209
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
7.8/10 Good! (1,005 reviews)
Stains on the carpet floor. They initially alloted a room that was not cleaned, later we were shifted to a cleaned room when we told the issue. No phone lines between rooms were working. Utensils were old and lots of scrteches on pans. For few days only one elevator was working. Some of the guests at the property were lound on the parking and there was also incident where cops were called to interfere.

Reviewed on Oct 7, 2026

The Wildwood Hotel

The Wildwood Hotel

$279
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,679 reviews)
The Knight Center at Washington University

The Knight Center at Washington University

Save 100% on your flight
$345
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.4/10 Exceptional! (690 reviews)
All great except the very noisy toilet. When you flesh, you probably can wake up whole saint louis

Reviewed on Oct 7, 2026

Moonrise Hotel

Moonrise Hotel

Delmar Loop
Save 100% on your flight
$351
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (2,029 reviews)
I love the Moonrise and will stay here anytime I come to St. Louis. I have stayed here multiple times and never had a negative experience. Easy parking, walking to food, next door to concert venues, plus pet friendly. The rooftop bar is great too!

Reviewed on Oct 7, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Save 100% on your flight
$427
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,062 reviews)

Where to stay in Downtown West

Find the best Downtown West areas and neighborhoods for the activities you enjoy most. Learn more about Downtown West
A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

3 out of top 10 points of interest in this area

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis
The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Find hotels in Clayton
A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Find hotels in Central West End
A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Find hotels in St. Charles Historic District
A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Find hotels in Creve Coeur

Downtown West Hotel Deals

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$104 nightly
$122 total
Oct 18 - Oct 19
Total with taxes and fees
8.8/10 Excellent! (2,229 reviews)
"One of the only hotels in the area with free on-site parking, can park in the garage on site or in regular lot and come and go and you please"

Reviewed on Oct 7, 2026

Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
$173 total
Nov 1 - Nov 2
Total with taxes and fees
9/10 Wonderful! (2,129 reviews)
"Great location. Parking is expensive unless you can find street parking. It is a really neat old building make sure you walk around! We had a weird light that would not turn off I our room. Maintenance came and had to put tape and cardboard over it. Effective but not a long term solution for dum ..."

Reviewed on Oct 7, 2026

21C Museum Hotel St Louis
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
$101 nightly
$118 total
Oct 14 - Oct 15
Total with taxes and fees
7.8/10 Good! (974 reviews)
"Great location Downtown. Staff were great. Parking on street is fine."

Reviewed on Oct 5, 2026

Home2 Suites by Hilton St. Louis Downtown
See all 1,961 properties in Downtown West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Downtown West attractions

A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
See properties
A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
See properties
The National Blues Museum in Saint Louis, Missouri.

Washington Avenue Historic District

Food, fashion and the blues reign supreme in this creative district of downtown St. Louis. Wander elegant tree-lined streets and delve into city history at museums.
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A historic building with a red-tiled roof and ornate architectural details.

St. Louis City Hall

Learn about the local history of St. Louis with a stop at St. Louis City Hall. Experience the area's acclaimed art scene or attend a baseball game.
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St. Louis Aquarium at Union Station

9.0/10 (17 reviews)
Meet the animals who live at St. Louis Aquarium at Union Station during your trip to St. Louis.
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Energizer Park

Catch an event at Energizer Park during your trip to St. Louis.
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The St. Louis Wheel

9.2/10 (13 reviews)
Enjoy an outing to The St. Louis Wheel during your stay in St. Louis.
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Stifel Theatre

You can make plans for a show at Stifel Theatre on your trip to St. Louis.
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Things to do

Self Guided Walking & Driving Audio Tour St. Louis

Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP

$15
per traveler
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
Landmarks Downtown-West Walking Tour

Landmarks Downtown-West Walking Tour

$20
per adult
Landmarks Downtown-West Walking Tour
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.