Downtown West Vacations from $611

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Your Downtown West Vacation

Downtown West is beckoning! Whatever type of getaway you're organizing, you can experience and see more of this neighborhood with a Downtown West vacation package. Your trip to Downtown West wouldn't be complete without exploring popular attractions nearby such as Busch Stadium, Gateway Arch and Dome at America’s Center. Whatever your travel goals or budget, booking a perfect Downtown West vacation is easy with Expedia.

The Latest Downtown West Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield
The Wildwood Hotel
Alhonna Resort LLC
Hilton St. Louis at the Ballpark
Ameristar Casino Resort and Spa

Where to stay in Downtown West

Find the best Downtown West areas and neighborhoods for the activities you enjoy most. Learn more about Downtown West

Downtown West Hotel Deals

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from May 24 to May 25
$173 total
May 24 - May 25
Total with taxes and fees
9/10 Wonderful! (1,814 reviews)
The staff was excellent, I want to point that out first and foremost from the valet to the front desk. However, the bed was hard, the pillows were harder, and the A/C unit made a loud knocking/clicking noise for 20 seconds every time the unit cycled. Also, the phone in the room did not work, so I ...

Reviewed on May 3, 2026

21C Museum Hotel St Louis
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from May 25 to May 26
$140 total
May 25 - May 26
Total with taxes and fees
8.8/10 Excellent! (1,950 reviews)
Check in was easy and staff was friendly and helpful. Breakfast was a good selection of hot and cold foodsz juices and coffee. They have nightly snacks and drink options from 5-7pm that were pretty good. Everything was clean and maintained. The restaurant that's attached to the hotel offers shuttles ...

Reviewed on May 2, 2026

Pear Tree Inn St. Louis Near Union Station
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

3 out of 5
1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $114 total per night from May 21 to May 22
$114 total
May 21 - May 22
Total with taxes and fees
8/10 Very Good! (747 reviews)
We got a room on the corner of the building and it was so big and pretty. It was very clean. The room said 1 bed but it also had a couch with a pullout bed. Breakfast was good and free. Parking can be expensive. Felt safe here despite lots of homeless people downtown.

Reviewed on Apr 29, 2026

Home2 Suites by Hilton St. Louis Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Downtown West

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.