Downtown West Vacations from $279

Book a Hotel + Flight or Car together to unlock savings

Your Downtown West Vacation

Downtown West is beckoning! Whatever type of getaway you're organizing, you can experience and see more of this neighborhood with a Downtown West vacation package. Your trip to Downtown West wouldn't be complete without exploring popular attractions nearby such as Busch Stadium, Gateway Arch and Dome at America’s Center. Whatever your travel goals or budget, booking a perfect Downtown West vacation is easy with Expedia.

The Latest Downtown West Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Staybridge Suites O'Fallon Chesterfield by IHG
The Wildwood Hotel
Hilton Garden Inn Chesterfield
The Cheshire
DoubleTree by Hilton Hotel St. Louis - Chesterfield

Where to stay in Downtown West

Find the best Downtown West areas and neighborhoods for the activities you enjoy most. Learn more about Downtown West

Downtown West Hotel Deals

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $116 total per night from Sep 3 to Sep 4
$116 total
Sep 3 - Sep 4
Total with taxes and fees
8.8/10 Excellent! (1,588 reviews)
"The evening snacks and drinks were a great little bonus"

Reviewed on Aug 25, 2025

Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Sep 1 to Sep 2
$173 total
Sep 1 - Sep 2
Total with taxes and fees
21C Museum Hotel St Louis
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $132 total per night from Sep 3 to Sep 4
$132 total
Sep 3 - Sep 4
Total with taxes and fees
Drury Inn & Suites St. Louis Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Downtown West

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.