Downtown West Vacations from $260

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Your Downtown West Vacation

Downtown West is beckoning! Whatever type of getaway you're organizing, you can experience and see more of this neighborhood with a Downtown West vacation package. Your trip to Downtown West wouldn't be complete without exploring popular attractions nearby such as Busch Stadium, Gateway Arch and Dome at America’s Center. Whatever your travel goals or budget, booking a perfect Downtown West vacation is easy with Expedia.

The Latest Downtown West Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Riverport
$260
per person
Oct 8 - Oct 11
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
7.6/10 Good! (1,015 reviews)
There was nothing unique about the property. Would not recommend this place at all.we were on the 3rd floor to which our room had no working a.c in the living room area even tho it ran on 60 degrees. The pull out couch was not comfortable at all with very noticeable stains on the mattress. There was dirty dishes left in the dishwasher from the previous person.Key card to our room kept deactivated and you would have togo down multiple times to get it re active. We spent 5 days iheree becuse there was no refunds. And we had no other chOoice.ne of the ice machines worked in the entire hotel on all floors. They had 1 working elevators in the way back of the hotel for allfloors .So we had to carry the luggage up 3 flights of stairs. The hallway are not toclean.VERY!VERY!OUT DATEDALL PICTURES YOU SEE ON ANY ON LINE DOES NOT MATCH WHAT THE HOTEL IS. The breakfast was terrible boiled eggs and dried up cereal and 1 waffle maker.Not worth the price they charge for the rooms.The location is definitely not co n vient Definitely would not recommend.

Reviewed on Sep 4, 2026

The Wildwood Hotel

The Wildwood Hotel

Save 100% on your flight
$322
per person
Oct 13 - Oct 16
found 2 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,657 reviews)
Remodeled and Inviting Free EV

Remodeled and Inviting Free EV

Save 100% on your flight
$328
per person
Oct 23 - Oct 26
just found
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (2 reviews)
It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it

Reviewed on Aug 7, 2026

Residence Inn by Marriott St. Louis West County

Residence Inn by Marriott St. Louis West County

$724
per person
Oct 12 - Oct 17
just found
Roundtrip flight included
Seattle (SEA) to St. Louis (STL)
9.2/10 Wonderful! (265 reviews)
Ive stayed here before. Rooms are nice because they have a desk kitchen snd couch. Bed was not good. We stayed here because our ac went out. I called and confirmed pet friendly booked and paid for the room only to arrive and be told its $100 pet fee. Thats not fair or ok.

Reviewed on Sep 4, 2026

Moonrise Hotel

Moonrise Hotel

Delmar Loop
Save 100% on your flight
$286
per person
Oct 16 - Oct 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (2,031 reviews)

Where to stay in Downtown West

Find the best Downtown West areas and neighborhoods for the activities you enjoy most. Learn more about Downtown West
A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis

3 out of top 10 points of interest in this area

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

A street with parked cars, a building with a sign reading "Brennan's", and a tree in front.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Downtown West Hotel Deals

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
$114 total
Sep 20 - Sep 21
Total with taxes and fees
7.8/10 Good! (939 reviews)
"Valet parking expensive. Good breakfast. I didn’t walk the area when it got dark."

Reviewed on Sep 5, 2026

Home2 Suites by Hilton St. Louis Downtown
21C Museum Hotel St Louis

21C Museum Hotel St Louis

1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
$173 total
Sep 27 - Sep 28
Total with taxes and fees
9/10 Wonderful! (2,092 reviews)
"Excellent hotel , friendly , loved all public area including the pool"

Reviewed on Sep 5, 2026

21C Museum Hotel St Louis
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
$114 total
Sep 13 - Sep 14
Total with taxes and fees
Tru By Hilton St. Louis Downtown
See all 1,967 properties in Downtown West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Downtown West attractions

A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
See properties
A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)
This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.
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A city street with a red car, a blue fire hydrant, and a building with a spire.

Washington Avenue Historic District

Food, fashion and the blues reign supreme in this creative district of downtown St. Louis. Wander elegant tree-lined streets and delve into city history at museums.
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A historic building with a red-tiled roof and ornate architectural details.

St. Louis City Hall

Learn about the local history of St. Louis with a stop at St. Louis City Hall. Experience the area's acclaimed art scene or attend a baseball game.
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St. Louis Aquarium at Union Station

9.0/10 (17 reviews)
Meet the animals who live at St. Louis Aquarium at Union Station during your trip to St. Louis.
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Energizer Park

Catch an event at Energizer Park during your trip to St. Louis.
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The St. Louis Wheel

9.2/10 (13 reviews)
Enjoy an outing to The St. Louis Wheel during your stay in St. Louis.
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Stifel Theatre

You can make plans for a show at Stifel Theatre on your trip to St. Louis.
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Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
Landmarks Downtown-West Walking Tour

Landmarks Downtown-West Walking Tour

$20
per adult
Landmarks Downtown-West Walking Tour
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

$25
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.