
Eastern Oregon Vacations from $1,130
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Eastern Oregon Vacation
Leave the travel planning to us with an Eastern Oregon vacation package. With everything arranged before you head off, all you'll have to do is relax and enjoy this destination's countless delights. Kick off your trip to Eastern Oregon with some time exploring Pendleton visiting popular sights like Wildhorse Casino and Pendleton Woolen Mills. Baker City is another top city that draws crowds from far and wide. Baker City Mini-Loop and Adler House Museum are two of the top places to see in this destination. Expedia has flights, hotels, car rentals and more to help you create your very own customized Eastern Oregon vacation today.
The Latest Eastern Oregon vacation packages




Travelodge by Wyndham Hermiston
Reviewed on Sep 18, 2025

The Hotel Pendleton, Trademark Collection by Wyndham
Reviewed on Nov 21, 2025
Discover the most popular places to visit in Eastern Oregon

Hat Rock State Park
You can take time to visit Hat Rock State Park during your travels to Hermiston. While in this family-friendly area, you can savor the bars and coffeehouses.
Wildhorse Casino
Why not roll the dice with a visit to Wildhorse Casino during your visit to Mission? While you're here, you can savor the top-notch restaurants.
Wallowa Lake State Park
Commune with nature and explore the great outdoors at Wallowa Lake State Park during your travels in Joseph. Wander the lakeside or discover the mountain views in this family-friendly area.
What to do in Eastern Oregon

Half-Day Multnomah Falls & Gorge Waterfalls Tour

Portland: Willamette River 2.5-hour Dinner Cruise

Portland: Brunch Cruise on Willamette River
Eastern Oregon Hotel Deals

Oxford Suites Hermiston
Our room was spacious, clean and quiet. Breakfast was good and the servers were very nice.
Reviewed on Nov 15, 2025

Oxford Suites Pendleton
The room was clean, larger than normal size, a little loud in the evening due to the room being on the side of the interstate, the bathroom had a little smell. I believe it was the shower curtain. But overall cleanliness was very good. Hotel staff extremely friendly. Buffet Was very good.
Reviewed on Nov 24, 2025

Red Lion Inn & Suites Ontario
Despite the hotel being very basic. It was clean, the bed was comfortable and it was exactly what I needed. What the hotel lacked in fancy details it more than made up for with it's friendly helpful staff. Shawn at the front desk was helpful and efficient and gracious. This is a little hotel, close ...
Reviewed on Nov 17, 2025
Find the Best Eastern Oregon Vacation Packages
Eastern Oregon Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Tri-Cities Airport (PSC) |
More vacations you might like
Explore a world of travel with Expedia
- Unity Hotels
- Sumpter Hotels
- B&B in Sumpter
- Cabin Rentals in Sumpter
- Motels in Sumpter
- Vacation Homes in Sumpter
- 3 Star Hotels in Sumpter
- RV Parks in Sumpter
- Granite Hotels
- Prairie City Hotels
- Cabin Rentals in Prairie City
- Motels in Prairie City
- 3 Star Hotels in Prairie City
- Hotels near Malheur National Forest
- Baker City Hotels
- Hotels near Quail Ridge Golf Course
- Pet-friendly Hotels in Baker City
- Cheap Hotels in Baker City
- Best Western Hotels in Baker City
- Hotels with an Indoor Pool in Baker City
- Historic Hotels in Baker City
- Motels in Baker City
- Cabin Rentals in Baker City
- Hotels with Free Breakfast in Baker City
- Wyndham Hotels in Baker City
- Hotels with Hot Tubs in Baker City
- Family Hotels in Baker City
- Resorts & Hotels with Spas in Baker City
- Hotels with Restaurants in Baker City
- Gay friendly Hotels in Baker City
- Hotels with Bars in Baker City
- Luxury Hotels in Baker City
- Vacation Homes in Baker City
- Hotel Wedding Venues Hotels in Baker City
- Romantic Hotels in Baker City
- B&B in Baker City
- Hotels with Connecting Rooms in Baker City
- Hotels with Laundry Facilities in Baker City
- Extended Stay Hotels in Baker City
- Honeymoon Resorts & in Baker City
- Hotels with Room Service in Baker City
- Hotels with an Outdoor Pool in Baker City
- 4 Star Hotels in Baker City
- 3 Star Hotels in Baker City
- Hotels with a Pool in Baker City
- Apartments in Baker City
- Ski Hotels in Baker City
- Hotels with Free Parking in Baker City
- Motel 6 Hotels in Baker City
- Hotels near Anthony Lakes Ski Area
- Hotels near Baker City Mini-Loop
- Hotels near Baker Tower
- Hotels near Adler House Museum
- Hotels near Baker Heritage Museum
- Hotels near Oregon Trail Monument
- Haines Hotels
- Flights to Unity
- Flights from Unity
- Flights from Greenhorn
- Flights to Sumpter
- Flights to Prairie City
- Flights from Baker City
- Flights to Baker City
- Flights from Medford to Baker City
- Flights from Detroit to Baker City
- Flights from Tokyo to Baker City
- Flights from Tucson to Baker City
- Flights from San Luis Obispo to Baker City
- Flights to Haines
- Visit Unity
- Sumpter Vacations
- Visit Sumpter
- Visit Prairie City
- Malheur National Forest
- Old Downtown Area
- Quail Ridge Golf Course
- Baker City Vacations
- Anthony Lakes Ski Area
- Baker City Mini-Loop
- Baker Tower
- Adler House Museum
- Visit Baker City
- Baker Heritage Museum
- Oregon Trail Monument
- Chinese Cemetery
- Visit Haines
- Car rentals near Unity
- Car rentals near Sumpter
- Car rentals near Prairie City
- Car rentals near Baker City
- Enterprise Rental Cars in Baker City
- Hertz Rental Cars in Baker City
- Avis Rental Cars in Baker City
- Alamo Rent A Car Rental Cars in Baker City
- National Car Rental Rental Cars in Baker City
- Car rentals near Baker City Mini-Loop
- Car rentals near Oregon Trail Monument




















