El Santuario Vacations from $378

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The Latest El Santuario vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Villa Real

Hotel Villa Real

2.5 out of 5
Laureles - Estadio
Save 100% on your flight
Price was $773, price is now $378 per person
$378
per person
Feb 7 - Feb 12
found 1 day ago
Roundtrip non-stop flight included
San Juan (SJU) to Medellín (MDE)
7.2/10 Good! (52 reviews)
Estuvo genial gracias

Reviewed on Sep 28, 2025

Hotel Du Parc

Hotel Du Parc

4.5 out of 5
El Poblado
Save 100% on your flight
Price was $1,196, price is now $566 per person
$566
per person
Feb 1 - Feb 7
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
9.4/10 Exceptional! (1,001 reviews)
Breakfast buffet is royalty

Reviewed on Dec 1, 2025

MYLOS Hotel Boutique

MYLOS Hotel Boutique

3 out of 5
Save 100% on your flight
Price was $1,312, price is now $713 per person
$713
per person
Jan 15 - Jan 20
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Medellín (MDE)
7.2/10 Good! (5 reviews)
Mylos hotel was a hidden gem in Guatape. Such a cute luxury boutique hotel and near everything. From the moment we stepped in we were greeted by the wonderful staff. Hotel look just like the pictures. Will definitely stay here again in the future.

Reviewed on Nov 20, 2025

The Host Medellin Only Adults

The Host Medellin Only Adults

3 out of 5
El Poblado
Save 100% on your flight
Price was $1,012, price is now $566 per person
$566
per person
Feb 1 - Feb 7
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
10/10 Exceptional! (6 reviews)
Brand new hotel, very comfortable, excellent location, close to restaurants and parks, staff very polite and helpful, rooms very clean and comfortable, beautiful architecture, and great decoration including three original paintings by David Manzur.

Reviewed on Nov 19, 2025

Blues Suites Medellin

Blues Suites Medellin

4 out of 5
El Poblado
Save 100% on your flight
Price was $850, price is now $477 per person
$477
per person
Feb 1 - Feb 7
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
9/10 Wonderful! (981 reviews)
Excelente hotel, excelente staff y muy buena ubicación con estacionamiento. Todo súper bien y estaré regresando pronto

Reviewed on Dec 1, 2025

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El Santuario Hotel Deals

Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $73 total per night from Dec 22 to Dec 23
$73 total
Dec 22 - Dec 23
9/10 Wonderful! (999 reviews)
We chose the Hotel for the location to walkable restaurants and Bars, the roof top restaurant and pool. We were a 100% satisfied! The staff is very friendly, the room we chose was tiny but that’s what we booked, because we did not plan to spend much time there. It was cleaned every day very well. ...

Reviewed on Nov 30, 2025

Heiss Hotel By Jalo
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

3.5 out of 5
# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $78 total per night from Dec 2 to Dec 3
$78 total
Dec 2 - Dec 3
9.2/10 Wonderful! (256 reviews)
The staff are so friendly and helpful. You feel safe inside the hotel, but outside there is to much movement and noise.

Reviewed on Nov 25, 2025

Calle Flora Hotel by Jalo
York Luxury Suites Medellín

York Luxury Suites Medellín

4 out of 5
Carrera 43a 17sur 63 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $158 total per night from Dec 3 to Dec 4
$158 total
Dec 3 - Dec 4
9.4/10 Exceptional! (1,408 reviews)
Highly Recommend!!

Reviewed on Nov 29, 2025

York Luxury Suites Medellín
See all 2,592 properties in El Santuario
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best El Santuario Vacation Packages

El Santuario Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Jose Maria Cordova Intl. Airport (MDE)
Population
17,700
Top Sights
Rock of Guatapé, Comfama Tutucán Recreational Park and Estadio Alberto Grisales Stadium

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Frequently asked questions

How much does an El Santuario vacation package cost?
Offering excellent value package deals from $378 on Expedia, you'll be pleasantly surprised at how much a vacation to El Santuario costs! Expedia's packages mean less travel planning for you and greater savings.
What are the cheapest months to go to El Santuario?
November, December and January are great times to look for cheap El Santuario vacation packages. Choosing to travel in quieter periods means you can generally find lower prices on hotels and flights.
How many days is enough for El Santuario?
The ideal length of your El Santuario vacation depends on what you'd like to see. Usually, a handful of days to a week will give you enough time to check out all the main sights and explore some hidden spots along the way.
How to find the best El Santuario package deals?
Begin your search for an El Santuario package deal by entering your destination and preferred travel dates under our "Packages" tab. Then select a few filters, like "Property type" and "Guest rating," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the ideal El Santuario package deal straight away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your El Santuario escape off to a flying start.
Is it cheaper to book an El Santuario vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, car rental and flight into one great-value price and enjoy significant savings. You'll generally snag a better deal than booking each component separately. And you'll still enjoy the freedom to create a tailored El Santuario vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to El Santuario?
If you have your El Santuario vacation dates finalized, book early to grab some fantastic deals. With Expedia, you can generally reserve some flights up to one year in advance. Prefer spur-of-the-moment getaways? Our last-minute deals are ideal for jetting off on a whim.
How to plan a trip to El Santuario?

  1. Choose when to travel: Check your schedule and get your bags packed. Your preferred time of year and the type of activities on offer will also help you decide when to escape to El Santuario.
  2. Budget wisely: Besides the price of your hotel, you'll need to factor in other expenses. These include flights, food and transportation. Also, set aside a little extra for unexpected costs that could crop up during your trip to El Santuario.
  3. Organize your El Santuario getaway with our trip planning tool: Search for and book accommodations and things to do all in one place. You can also collaborate with family and friends to plan an unforgettable trip to El Santuario together.
  4. Set the duration of your trip: Start by listing all the attractions you'd like to get to in El Santuario. Then, estimate how long you'll need at each, along with any travel time.
  5. Combine your flights and hotel: Awesome destination, check. Length of stay, check. All that's left now is to pick an El Santuario vacation package that brings all your bookings together.
  6. Add on experiences and excursions: Read our travel guide to find some awesome things to do in El Santuario. Book tickets or make reservations before you go to save time and avoid the stress of looking for activities when you arrive.

Does Expedia offer Book Now, Pay Later El Santuario vacation packages?
Your El Santuario break is meant to be a relaxing escape from your busy life, not a reason for money worries. So to allow you a bit more flexibility, we've teamed up with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.