Sanctuary, FL
Sanibel
Visit Sanctuary
Things to do
Fort Myers Beach Sunset and Dolphin Watching Cruise
$59
per adult
100% of travellers recommend
Parasailing Adventure on Fort Myers Beach (400 Foot Flight)
$105
per adult
94% of travellers recommend
Sunset Cruise Fort Myers Beach
$48
per adult
100% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
$64
per adult
100% of travellers recommend
Sanctuary Hotel Deals
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $266 total per night from Nov 11 to Nov 12
$266 total
Nov 11 - Nov 12
Total with taxes and fees
Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ...
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
$210 nightly
The price is $234 total per night from Nov 1 to Nov 2
$234 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,712 reviews)
"Convenient place to stay after coming in on the Key West Express passenger ferry."
Reviewed on Oct 27, 2026
The Lighthouse Resort Inn & Suites
1051 5th St Fort Myers Beach FL
$147 nightly
The price is $164 total per night from Nov 3 to Nov 4
$164 total
Nov 3 - Nov 4
Total with taxes and fees
Stay at this hotel in Fort Myers Beach. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,841 reviews)
"The lighthouse is our go to spot. Beautiful rooms. Great staff. New pool is amazing. Book go and have a blast"
Reviewed on Oct 27, 2026
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
$101 nightly
The price is $113 total per night from Nov 1 to Nov 2
$113 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
$165 nightly
The price is $184 total per night from Nov 1 to Nov 2
$184 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, 3 restaurants, and a beach locale. Popular attractions Key West Express and Crescent Beach ...
8.8/10 Excellent! (2,154 reviews)
"Came in on a Friday to Wednesday stay. First day was fine. On Saturday we watched a dog being led by their owners take a major crap on the beach where people walked.. we called down to the front desk to let them know..nothing happened as we watchrd and waited. On Sunday we put out our clean the room ..."
Reviewed on Oct 27, 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
$204 nightly
The price is $227 total per night from Oct 29 to Oct 30
$227 total
Oct 29 - Oct 30
Total with taxes and fees
Book a stay at this beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
9.2/10 Wonderful! (2,385 reviews)
"Absolutely fantastic location! We just stayed for one night but the staff is friendly and accommodating. Having the bar in sight was nice and the pool was fabulous. Plenty of lounge chairs on the pool deck and the beach. We can’t wait to return."
Reviewed on Oct 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Sanctuary
Find the best Sanctuary areas and neighborhoods for the activities you enjoy most.
Mid Island
While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.
West End
While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.
East End
While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.
Beachview Country Club Estates
If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.
Gulf Shores
While there might not be top attractions in Gulf Shores, you can explore the larger area and discover places like Bowman's Beach and J. N. Ding Darling National Wildlife Refuge.
