Sanctuary, FL
Sanibel
Visit Sanctuary
Things to do
Fort Myers Beach Sunset and Dolphin Watching Cruise
$63
per adult
100% of travellers recommend
Sunset Cruise Fort Myers Beach
$48
per adult
100% of travellers recommend
Parasailing Adventure on Fort Myers Beach (400 Foot Flight)
$105
per adult
94% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
$64
per adult
100% of travellers recommend
Sanctuary Hotel Deals
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
$208 nightly
The price is $232 total per night from Sep 2 to Sep 3
$232 total
Sep 2 - Sep 3
Total with taxes and fees
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,482 reviews)
"it was a great day"
Reviewed on Aug 25, 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
$150 nightly
The price is $167 total per night from Aug 30 to Aug 31
$167 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, 3 restaurants, and a beach locale. Popular attractions Key West Express and Estero Boulevard ...
8.8/10 Excellent! (1,956 reviews)
"Property was in a good location. The beach was nice. The hotel held very strict rules presumably controlling spring break."
Reviewed on Aug 26, 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
$206 nightly
The price is $230 total per night from Aug 30 to Aug 31
$230 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
9.2/10 Wonderful! (2,239 reviews)
"We loved the location to all of our stops during our stay we went to museums and preserves and beaches every day"
Reviewed on Aug 25, 2026
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
$223 nightly
The price is $248 total per night from Sep 9 to Sep 10
$248 total
Sep 9 - Sep 10
Total with taxes and fees
Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ...
8.6/10 Excellent! (1,014 reviews)
"Everything excellent"
Reviewed on Aug 26, 2026
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
$103 nightly
The price is $115 total per night from Sep 7 to Sep 8
$115 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Pink Shell Beach Resort and Marina
275 Estero Blvd Fort Myers Beach FL
$257 nightly
The price is $287 total per night from Aug 31 to Sep 1
$287 total
Aug 31 - Sep 1
Total with taxes and fees
Book a stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools, and a full-service spa. Our guests praise the breakfast and the ...
9.4/10 Exceptional! (1,435 reviews)
"We loved everything about this resort! Very clean & well taken care of. Beautiful serene beachfront, great amenities and wonderful staff who felt more like family."
Reviewed on Aug 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Sanctuary
Find the best Sanctuary areas and neighborhoods for the activities you enjoy most.
Mid Island
While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.
West End
While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.
East End
While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.
Beachview Country Club Estates
If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.
Gulf Shores
While there might not be top attractions in Gulf Shores, you can explore the larger area and discover places like Bowman's Beach and J. N. Ding Darling National Wildlife Refuge.