
Great Plains Vacations from $221
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Your Great Plains Vacation
Leave the travel planning up to us with a Great Plains vacation package. With everything organized before you leave home, the only thing left for you to do is sit back, relax and experience this destination's culture and beauty. Your trip to Great Plains wouldn't be complete without experiencing some of its most well-known cities, starting with Houston. Two of the top attractions here include NRG Stadium and MD Anderson Cancer Center. Denver should also be on the itineraries of all Great Plains travelers. Visitors to this destination love Union Station and Empower Field at Mile High. Expedia has flights, hotels and everything else you need to help you curate your very own tailored Great Plains vacation today.
The Latest Great Plains vacation packages

Broadmore Miami Beach
Reviewed on Oct 25, 2025

Los Angeles Deluxe Suites - 2 Bedrooms & 2 Bathrooms
Reviewed on Jul 31, 2025

The Shelborne By Proper, a Member of Design Hotels
Reviewed on Oct 28, 2025

Hollywood Inn Suites Hotel
Reviewed on Oct 30, 2025

Where to stay in Great Plains

Downtown Denver
Dive into this bustling financial and entertainment hub, featuring the 16th Street pedestrian mall, Larimer Square, and the Theatre District. Catch a game at Coors Field or Ball Arena, and explore the neighborhood's vibrant dining scene.
Discover the most popular places to visit in Great Plains

Union Station
Combining transit, accommodations, shopping, dining, and events, this landmark building in downtown Denver offers history and excitement in the Mile High City.

Mount Rushmore
Explore the great outdoors at Mount Rushmore, a popular spot to commune with nature in Keystone. Discover the area's notable monuments, or seek out its horseback riding.

Garden of the Gods
Get a taste for the Colorado landscape as you explore this huge city park on your own or during a guided bus or Segway tour.
Great Plains Hotel Deals

Hilton Denver City Center
I was sad to see that the pool was closed. But really liked the food/breakfast and credit option. It was helpful when there was some confusion at the front desk. However, the front desk made it right. So I really appreciate it as I was traveling with my family.
Reviewed on Oct 29, 2025

Sonesta Denver Downtown
Clean room, fun area, would visit again next time I’m in the downtown area
Reviewed on Oct 28, 2025

Renaissance Denver Hotel & Conference Center
Nice and clean
Reviewed on Oct 28, 2025























