A historic downtown street with vintage buildings, a church steeple, and a prominent clock tower.

Great River Road Vacation Rentals

Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for Great River Road vacation rentals

Coffee/tea maker, fridge, microwave, oven

1. Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
The Hill
9.8 out of 10, Exceptional, (199 reviews)
"Great cottage, pet friendly, wonderful neighborhood to explore and many great food options within walking distance. Would definitely stay again at this cottage."
United States
Scott J.
$136 nightly
The price is $148
Sep 30 - Oct 1
Total with taxes and fees
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
Cabin, 1 Queen Bed | Private kitchen | Mini-fridge, stovetop, cookware/dishes/utensils, paper towels

2. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
10.0 out of 10, Exceptional, (107 reviews)
"I really enjoyed my time at the stay !"
United States
Ronrecus
$141 nightly
The price is $160
Oct 21 - Oct 22
Total with taxes and fees
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Interior

3. Spacious, cozy home in Saint Louis

Spacious, cozy home in Saint Louis
St. Louis
10.0 out of 10, Exceptional, (45 reviews)
"Very clean. We had a nice stay."
United States
John V.
$256 nightly
The price is $274
Sep 28 - Sep 29
Total with taxes and fees
Spacious, cozy home in Saint Louis
Property grounds

4. Countryside Private Guest Room

Countryside Private Guest Room
Freeburg
9.8 out of 10, Exceptional, (29 reviews)
"Awesome place to stay really nice host would highly recommend!!!!"
United States
Cayson P.
$92 nightly
The price is $98
Sep 24 - Sep 25
Total with taxes and fees
Countryside Private Guest Room
Desk, iron/ironing board, WiFi (free), bed sheets

5. Hudson Inn & Suites

Hudson Inn & Suites
3.0 star property
Hudson
8.2 out of 10, Very good, (926 reviews)
"Friendly staff and safe place to stay."
United States
Terry
$91 nightly
The price is $99
Oct 23 - Oct 24
Total with taxes and fees
Hudson Inn & Suites
Property amenity

6. Turn On Inn

Turn On Inn
3.0 star property
Lake Village
9.6 out of 10, Exceptional, (94 reviews)
"We really enjoyed our overnight stay here. There were 5 of us and Cabin 1 accommodated us perfectly. The campground was very peaceful, quiet, and clean as was the cabin. Will definitely book again next year!"
United States
Richard
$103 nightly
The price is $114
Oct 23 - Oct 24
Total with taxes and fees
Turn On Inn
Front of property

7. Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos
3.0 star property
Nauvoo
9.8 out of 10, Exceptional, (449 reviews)
"A great place to stay!"
United States
Renae
$144 nightly
The price is $153
Sep 23 - Sep 24
Total with taxes and fees
Nauvoo Vacation Villas & Condos
Coffee/tea maker, fridge, microwave, oven

8. Aunt Lele's Cozy Cottage

Aunt Lele's Cozy Cottage
Quincy
9.8 out of 10, Exceptional, (46 reviews)
"Perfect place for our family of 5 to enjoy a weekend visiting my wife’s family."
United States
Matt B.
$145 nightly
The price is $165
Oct 11 - Oct 12
Total with taxes and fees
Aunt Lele's Cozy Cottage
Terrace/patio

9. Mississippi River Cabin

Mississippi River Cabin
Bellevue
9.8 out of 10, Exceptional, (47 reviews)
"Great place"
United States
Greg G.
$242 nightly
The price is $272
Sep 27 - Sep 28
Total with taxes and fees
Mississippi River Cabin
Exterior

10. Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.6 out of 10, Exceptional, (50 reviews)
"We enjoyed our stay at the well outfitted cabin near the Shawnee Wine Trail. Cabin is conveniently located near Giant City State Park and the lodge restaurant. "
United States
Janine B.
$199 nightly
The price is $220
Sep 28 - Sep 29
Total with taxes and fees
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Smart TV, stereo

11. Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.

Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.
Bellevue
9.8 out of 10, Exceptional, (128 reviews)
"Super convenient and comfy place to stay in the Bellevue area."
United States
Bruce B.
$182 nightly
The price is $203
Sep 23 - Sep 24
Total with taxes and fees
Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.
Exterior detail

12. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (75 reviews)
"Very clean and comfortable stay"
United States
Alison K.
$165 nightly
The price is $182
Sep 28 - Sep 29
Total with taxes and fees
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Interior

13. St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!
St. Charles Historic District
9.8 out of 10, Exceptional, (164 reviews)
"Very nice very clean property. Very much enjoyed our stay"
United States
Joe R.
$265 nightly
The price is $284
Sep 27 - Sep 28
Total with taxes and fees
St. Charles 1860's Gem - Sleeps 6!
Property grounds

14. Tamarack Point Homestead

Tamarack Point Homestead
Arcadia
10.0 out of 10, Exceptional, (46 reviews)
"What a wonderful place to stay. "
United States
Anonymous traveler
$111 nightly
The price is $117
Sep 23 - Sep 24
Total with taxes and fees
Tamarack Point Homestead
Exterior

15. Beautiful Modern Loft In Wine Country!

Beautiful Modern Loft In Wine Country!
Ste. Genevieve
10.0 out of 10, Exceptional, (291 reviews)
"The place was easy to find. Cute, clean, and relaxing. It was the perfect stay for our trip. Highly recommend. "
United States
Shayna P.
$171 nightly
The price is $192
Sep 24 - Sep 25
Total with taxes and fees
Beautiful Modern Loft In Wine Country!
Indoor pool, outdoor pool

16. Charming, Farmhouse Chic, Cozy|Fireplace|12 Min to Town|Beautiful View

Charming, Farmhouse Chic, Cozy|Fireplace|12 Min to Town|Beautiful View
The Galena Territory
10.0 out of 10, Exceptional, (55 reviews)
"Very nice place to stay. We enjoyed being there. "
United States
Ruth D.
$250 nightly
The price is $265
Sep 23 - Sep 24
Total with taxes and fees
Charming, Farmhouse Chic, Cozy|Fireplace|12 Min to Town|Beautiful View
42-inch Smart TV with digital channels

17. Roami at Century Plaza

Roami at Century Plaza
4.0 star property
Downtown Minneapolis
9.4 out of 10, Exceptional, (82 reviews)
"Location is great for being in Minneapolis, rooms were very clean and spacious. Has everything you needed plus more. Would definitely stay here again in the future."
Canada
Cory
$179 nightly
The price is $209
Sep 23 - Sep 24
Total with taxes and fees
Roami at Century Plaza
Exterior

18. Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (427 reviews)
"Beautiful quaint cabin! Had everything you could need. Would definitely recommend to anyone looking for a nice place to stay."
United States
Brandon
$189 nightly
The price is $209
Sep 24 - Sep 25
Total with taxes and fees
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Interior

19. Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus
Carbondale
9.2 out of 10, Wonderful, (154 reviews)
"Great place to get away while still being close enough to town"
United States
Travis S.
$134 nightly
The price is $141
Sep 23 - Sep 24
Total with taxes and fees
Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus
Interior

20. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.8 out of 10, Exceptional, (67 reviews)
"Great location for downtown exploring."
United States
Lisa B.
$172 nightly
The price is $186
Sep 28 - Sep 29
Total with taxes and fees
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Great River Road Hotel Reviews

Reel Paradise at Shore Slough

Reel Paradise at Shore Slough

10/10 Excellent
"We had a great stay and the place was clean and in a great location to downtown Lansing!"
Megan C. 2-night trip
Posted 10 hours ago
Reel Paradise at Shore Slough

Find out more about Great River Road

Everything you need to know about Great River Road vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Great River Road vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Great River Road vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Great River Road vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Great River Road. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Great River Road in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Great River Road rentals

At Expedia, we put the best Great River Road vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Great River Road rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Great River Road vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Great River Road. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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