A historic downtown street with vintage buildings, a church steeple, and a prominent clock tower.

Great River Road Vacation Rentals

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Check prices for these dates

In two weeks
Nov 6 - Nov 8
In two months
Dec 18 - Dec 20
In three months
Jan 15 - Jan 17
In four months
Feb 12 - Feb 14

Our top choices for Great River Road vacation rentals

A spacious living area with a gray sofa, a dining table with chairs, a large window with a city view, and a ceiling fan.

1. The Jungle Book | Marcel Stays

The Jungle Book | Marcel Stays
Downtown West
9.2 out of 10, Wonderful, (16 reviews)
"Clean, convenient, comfortable for family travel with pets."
United States
Persis B.
$295 nightly
The price is $298
Oct 20 - Oct 21
Total with taxes and fees
The Jungle Book | Marcel Stays
A brick wall with a wooden table and two chairs. There is a chalkboard sign on the wall and a small shelf with a vase of flowers.

2. Cozy Soulard 2BR w/ Free Parking

Cozy Soulard 2BR w/ Free Parking
Soulard
9.6 out of 10, Exceptional, (68 reviews)
"Enjoyed our visit to St. Louis. The host was very accommodating and helpful."
United States
Chad G.
$178 nightly
The price is $192
Oct 20 - Oct 21
Total with taxes and fees
Cozy Soulard 2BR w/ Free Parking
A modern kitchen with wooden cabinets, a central island, bar stools, and a ceiling fan.

3. 3 King Beds/3Baths Spacious by StayStLouis

3 King Beds/3Baths Spacious by StayStLouis
McKinley Heights
9.8 out of 10, Exceptional, (34 reviews)
"Property is exactly as it is advertised. It was very clean, and stocked with every item you might have forgotten, as a courtesy. The check-in process was clear and smooth. Our host was extremely professional, courteous, and accommodating to all of our needs. Highly recommend this property for your trip to STL!"
United States
Justine
$350 nightly
The price is $382
Oct 20 - Oct 21
Total with taxes and fees
3 King Beds/3Baths Spacious by StayStLouis
A modern living space with a wooden loft, a red chair, a potted plant, and a television on the wall.

4. Cozy Cottage Loft near Breweries Free Parking Pet Friendly

Cozy Cottage Loft near Breweries Free Parking Pet Friendly
Benton Park West
9.6 out of 10, Exceptional, (83 reviews)
"It was a nice cozy place! Good price for the money, bed was very comfortable! "
United States
Luke S.
$143 nightly
The price is $156
Nov 17 - Nov 18
Total with taxes and fees
Cozy Cottage Loft near Breweries Free Parking Pet Friendly
A two-story brick building with arched windows and a black door.

5. Brand New! Soulard Charmer - Pet Friendly.

Brand New! Soulard Charmer - Pet Friendly.
Soulard
9.6 out of 10, Exceptional, (58 reviews)
"Great accomodation would come back every time"
Germany
Daniel
$259 nightly
The price is $283
Oct 26 - Oct 27
Total with taxes and fees
Brand New! Soulard Charmer - Pet Friendly.
A dining area with a wooden table, grey upholstered chairs, a bench, a patterned rug, a brick wall, a framed picture, and a potted plant.

6. Centrally located in the Tower Grove East neighborhood!

Centrally located in the Tower Grove East neighborhood!
Tower Grove East
9.8 out of 10, Exceptional, (180 reviews)
"Great place!"
United States
Arthur S.
$141 nightly
The price is $152
Oct 21 - Oct 22
Total with taxes and fees
Centrally located in the Tower Grove East neighborhood!
A living room with a TV, wooden furniture, a fireplace, and a cozy seating area.

7. Charming 2-bedroom, cozy bungalow with sunroom in fabulous St. Louis with WiFi

Charming 2-bedroom, cozy bungalow with sunroom in fabulous St. Louis with WiFi
Bevo Mill
9.0 out of 10, Wonderful, (37 reviews)
"We enjoyed our stay, very quaint house and Julie was an amazing host "
United States
Lori O.
$230 nightly
The price is $250
Oct 21 - Oct 22
Total with taxes and fees
Charming 2-bedroom, cozy bungalow with sunroom in fabulous St. Louis with WiFi
A living room with a wooden entertainment center, a white sofa, and a dining area with a white railing.

8. Spacious, cozy home in Saint Louis

Spacious, cozy home in Saint Louis
St. Louis
10.0 out of 10, Exceptional, (46 reviews)
"Excellent communication and service, very clean, and nice place to stay. We enjoyed our stay!"
United States
Jennifer M.
$290 nightly
The price is $310
Oct 20 - Oct 21
Total with taxes and fees
Spacious, cozy home in Saint Louis
A rooftop pool area with checkered flooring, lounge chairs, and umbrellas.

9. Memoir Warehouse District

Memoir Warehouse District
4.0 star property
Arts/Warehouse District
9.4 out of 10, Exceptional, (483 reviews)
"Great location"
United States
Vincent
$177 nightly
The price is $209
Nov 3 - Nov 4
Total with taxes and fees
Memoir Warehouse District
A modern kitchen with white cabinets, a central island, and a hanging light fixture.

10. California Building

California Building
4.0 star property
New Orleans Central Business District
8.8 out of 10, Excellent, (330 reviews)
"Great room, great price and location."
United States
Phillip
$139 nightly
The price is $160
Oct 20 - Oct 21
Total with taxes and fees
California Building
A modern hotel room with a large window, a grey sofa, a wooden coffee table, a bed, and a view of a church spire.

11. Roami at Century Plaza

Roami at Century Plaza
4.0 star property
Downtown Minneapolis
9.4 out of 10, Exceptional, (115 reviews)
"The roof top is amazing make sure to enjoy that."
United States
Mason
$185 nightly
The price is $216
Nov 17 - Nov 18
Total with taxes and fees
Roami at Century Plaza
A modern living room with a glass dining table, grey sofas, and a large TV.

12. The Stallion

The Stallion
4.5 star property
Downtown Memphis
9.8 out of 10, Exceptional, (460 reviews)
"This place was wild and so surprisingly amazing. Clean huge, perfect amenities. We loved the layout, high ceiling everything!"
United States
Doreen
$211 nightly
The price is $251
Nov 18 - Nov 19
Total with taxes and fees
The Stallion
A bedroom with a bed, a wooden headboard, a window with a view of greenery, and a tray with breakfast items.

13. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
10.0 out of 10, Exceptional, (114 reviews)
"The stay here gets better every time."
United States
cynthia
$141 nightly
The price is $160
Nov 18 - Nov 19
Total with taxes and fees
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
A hotel room with two beds, green walls, and framed pictures of landscapes.

14. Hudson Inn & Suites

Hudson Inn & Suites
3.0 star property
Hudson
8.4 out of 10, Very good, (959 reviews)
"Friendly staff and safe place to stay."
United States
Terry
$81 nightly
The price is $88
Oct 20 - Oct 21
Total with taxes and fees
Hudson Inn & Suites
A modern living room with a sofa, a coffee table, and a rug. There is a kitchen in the background, and a bed with a white headboard is visible in the adjacent room.

15. Ironworks

Ironworks
3.5 star property
New Orleans Central Business District
9.6 out of 10, Exceptional, (77 reviews)
"Clean, safe, and great location. Would absolutely stay here again! The Ironworks Coffee is delicious and Ernst Cafe has the best priced beer."
United States
Jessica
$278 nightly
The price is $327
Oct 27 - Oct 28
Total with taxes and fees
Ironworks
A wicker chair with a cushion, a glass table with two wine glasses and a vase with flowers, and a plate of grapes.

16. The Pelican by Hosteeva

The Pelican by Hosteeva
4.0 star property
New Orleans Central Business District
9.4 out of 10, Exceptional, (58 reviews)
"Great location, wonderful stay! Our stay was awesome! The location was everything—extremely walkable and close to everything we wanted to see and do. The only downside was the limited bathroom space for a large party, which required a bit of coordination in the mornings. Overall, a great place to stay, and we’d definitely recommend it for the location alone!"
United States
james
$284 nightly
The price is $328
Oct 20 - Oct 21
Total with taxes and fees
The Pelican by Hosteeva
A view of a historic building with a tower and arched windows through a window with white flowers.

17. The Moose

The Moose
4.0 star property
Victorian Village Historic District
9.8 out of 10, Exceptional, (270 reviews)
"great stay"
United States
Ariel
$145 nightly
The price is $173
Oct 26 - Oct 27
Total with taxes and fees
The Moose
Property amenity

18. Turn On Inn

Turn On Inn
3.0 star property
Lake Village
9.6 out of 10, Exceptional, (95 reviews)
"Excellent place to stay I stay every time if available"
United States
Christi
$116 nightly
The price is $128
Oct 21 - Oct 22
Total with taxes and fees
Turn On Inn
A modern living room with a sofa, two side chairs, a coffee table, and a TV.

19. The Mayfair

The Mayfair
5.0 star property
French Quarter
10.0 out of 10, Exceptional, (66 reviews)
"Great location, elegant rooms & fun town to visit"
United States
Michael L
$291 nightly
The price is $335
Oct 20 - Oct 21
Total with taxes and fees
The Mayfair
A row of single-family homes with a well-maintained lawn and a tree in the foreground.

20. Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos
3.0 star property
Nauvoo
9.8 out of 10, Exceptional, (459 reviews)
"A great place to stay!"
United States
Renae
$135 nightly
The price is $143
Oct 27 - Oct 28
Total with taxes and fees
Nauvoo Vacation Villas & Condos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Great River Road Hotel Reviews

AmericInn by Wyndham Prairie du Chien

AmericInn by Wyndham Prairie du Chien

10/10 Excellent
"We enjoyed our stay!"
Angie 2-night trip
Posted less than an hour ago
AmericInn by Wyndham Prairie du Chien

Find out more about Great River Road

Everything you need to know about Great River Road vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Great River Road vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Great River Road vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Great River Road vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Great River Road. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Great River Road in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Great River Road rentals

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