A historic downtown street with vintage buildings, a church steeple, and a prominent clock tower.

Great River Road Vacation Rentals

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Check prices for these dates

In two weeks
Sep 11 - Sep 13
In two months
Oct 23 - Oct 25
In three months
Nov 20 - Nov 22
In four months
Dec 18 - Dec 20

Our top choices for Great River Road vacation rentals

Smart TV, offices

1. Classic Soulard 2BD King Master & Private Deck

Classic Soulard 2BD King Master & Private Deck
Soulard
9.8 out of 10, Exceptional, (62 reviews)
"Our family of 5 stayed for a long weekend. The host was extremely responsive. The place was clean, stocked well with all the necessities and more and there was plenty of room to spread out. The location was great and was within walking distance to tons of food, coffee places and Soulard market. The street can get busy on a Friday or Saturday night but there was still parking available and the noise wasn’t so much that it kept us awake. We would definitely stay here again!"
United States
Stephanie F.
$190 nightly
The price is $204
Aug 25 - Aug 26
Total with taxes and fees
Classic Soulard 2BD King Master & Private Deck
Coffee/tea maker, fridge, microwave, oven

2. Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
The Hill
9.8 out of 10, Exceptional, (195 reviews)
"Looks exactly like the pictures. Clean, beautiful shower. Friendly staff, had no problems answering questions, had all the things you needed to relax for a few days with a couple of friends. The neighborhood is lovely & peaceful at night. Beautiful yard. So pleased I came across this cottage. Thanks guy, our stay was awesome"
United States
Crystal
$141 nightly
The price is $152
Aug 26 - Aug 27
Total with taxes and fees
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
View from property

3. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
9.8 out of 10, Exceptional, (96 reviews)
"I really enjoyed my time at the stay !"
United States
Ronrecus
$141 nightly
The price is $160
Sep 22 - Sep 23
Total with taxes and fees
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Interior

4. Spacious, cozy home in Saint Louis

Spacious, cozy home in Saint Louis
St. Louis
10.0 out of 10, Exceptional, (43 reviews)
"The house was spacious and clean! It was perfect for our family, and convenient location. "
United States
Julie L.
$272 nightly
The price is $290
Sep 1 - Sep 2
Total with taxes and fees
Spacious, cozy home in Saint Louis
Property amenity

5. Turn On Inn

Turn On Inn
3.0 star property
Lake Village
9.6 out of 10, Exceptional, (92 reviews)
"Great accomodstion great price!"
United States
martha
$116 nightly
The price is $128
Aug 30 - Aug 31
Total with taxes and fees
Turn On Inn
Desk, iron/ironing board, WiFi (free), bed sheets

6. Hudson Inn & Suites

Hudson Inn & Suites
3.0 star property
Hudson
8.2 out of 10, Very Good, (901 reviews)
"Older hotel but well maintained and great value for the price."
United States
Dennis
$93 nightly
The price is $101
Sep 3 - Sep 4
Total with taxes and fees
Hudson Inn & Suites
Spruce Cabin Residences | Premium bedding, pillowtop beds, blackout drapes, WiFi (free)

7. Nature Link Resort

Nature Link Resort
3.0 star property
Nisswa
9.8 out of 10, Exceptional, (93 reviews)
"We had our kids wedding here and the whole stay was enjoyable and relaxing it made for a very memorable day in our kids life together."
United States
Jeffrey
$234 nightly
The price is $251
Sep 7 - Sep 8
Total with taxes and fees
Nature Link Resort
Exterior detail

8. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (72 reviews)
"The cabin was great! A few little extras for a welcome package. Did not skimp on the towels and bedding. Great decor. Loved it!!!"
United States
Ann
$165 nightly
The price is $182
Aug 25 - Aug 26
Total with taxes and fees
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Property grounds

9. Peter Ray House

Peter Ray House
Maeystown
10.0 out of 10, Exceptional, (75 reviews)
"This house was incredible. Loved the history and ambience of the town. Peter was one of the nicest homes I’ve stayed in over the years. I would highly recommend it."
United States
Eric
$212 nightly
The price is $225
Aug 25 - Aug 26
Total with taxes and fees
Peter Ray House
Smart TV, stereo

10. Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.

Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.
Bellevue
9.8 out of 10, Exceptional, (126 reviews)
"Super convenient and comfy place to stay in the Bellevue area."
United States
Bruce B.
$183 nightly
The price is $205
Aug 25 - Aug 26
Total with taxes and fees
Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.
Exterior detail

11. Pegasus Lair Upper Floor Apt.NoPetFee, NoChores.Short Walk to Satellite Venue!

Pegasus Lair Upper Floor Apt.NoPetFee, NoChores.Short Walk to Satellite Venue!
North Memphis
10.0 out of 10, Exceptional, (91 reviews)
"We had a wonderful time in Memphis, our host was extraordinarily friendly and helpful. The appartement is the best place you can imagine for your stay in Memphis: nice neighbourhood, near all the sights, lovely old house which is spotlessly clean, well equipped and beautifully decorated. We hope we will come back soon!"
United States
Nicole
$161 nightly
The price is $192
Aug 30 - Aug 31
Total with taxes and fees
Pegasus Lair Upper Floor Apt.NoPetFee, NoChores.Short Walk to Satellite Venue!
Exterior

12. Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (424 reviews)
"Cabin was cute and cozy!! "
United States
Anonymous traveler
$191 nightly
The price is $202
Aug 25 - Aug 26
Total with taxes and fees
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Exterior

13. Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.6 out of 10, Exceptional, (50 reviews)
"We enjoyed our stay at the well outfitted cabin near the Shawnee Wine Trail. Cabin is conveniently located near Giant City State Park and the lodge restaurant. "
United States
Janine B.
$193 nightly
The price is $213
Sep 14 - Sep 15
Total with taxes and fees
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Terrace/patio

14. Country cottage on 3 acres right outside of town close to UTM

Country cottage on 3 acres right outside of town close to UTM
Martin
10.0 out of 10, Exceptional, (75 reviews)
"Great location, easy check-in and check-out."
United States
Eric J.
$127 nightly
The price is $147
Aug 28 - Aug 29
Total with taxes and fees
Country cottage on 3 acres right outside of town close to UTM
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers

15. Memoir Warehouse District

Memoir Warehouse District
4.0 star property
Arts/Warehouse District
9.4 out of 10, Exceptional, (444 reviews)
"This was by far one of my faveorite stays !"
United States
Johaida
$134 nightly
The price is $159
Aug 30 - Aug 31
Total with taxes and fees
Memoir Warehouse District
Outdoor dining

16. The Alton House - Come experience tiny house living in beautiful Pepin!

The Alton House - Come experience tiny house living in beautiful Pepin!
Pepin
9.8 out of 10, Exceptional, (45 reviews)
"Amazing little place. Very clean and organized."
United States
Chris K.
$184 nightly
The price is $194
Aug 25 - Aug 26
Total with taxes and fees
The Alton House - Come experience tiny house living in beautiful Pepin!
Front of property

17. Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos
3.0 star property
Nauvoo
9.8 out of 10, Exceptional, (441 reviews)
"Staff were very helpful. Wonderful place. Qoiet and clean"
United States
Carrie
$140 nightly
The price is $149
Sep 3 - Sep 4
Total with taxes and fees
Nauvoo Vacation Villas & Condos
View from room

18. The Moose

The Moose
4.0 star property
Victorian Village Historic District
9.8 out of 10, Exceptional, (255 reviews)
"Great location. Very clean!"
United States
Courtney
$135 nightly
The price is $161
Sep 2 - Sep 3
Total with taxes and fees
The Moose
Exterior

19. Beautiful Modern Loft In Wine Country!

Beautiful Modern Loft In Wine Country!
Ste. Genevieve
10.0 out of 10, Exceptional, (288 reviews)
"The place was easy to find. Cute, clean, and relaxing. It was the perfect stay for our trip. Highly recommend. "
United States
Shayna P.
$181 nightly
The price is $202
Aug 26 - Aug 27
Total with taxes and fees
Beautiful Modern Loft In Wine Country!
Dining

20. Riverfront Cabin With Small Beach Short Drive From Nauvoo

Riverfront Cabin With Small Beach Short Drive From Nauvoo
Niota
8.2 out of 10, Very Good, (53 reviews)
"This was such a great getaway spot! We needed peace and we got it."
United States
Anonymous traveler
$95 nightly
The price is $101
Sep 22 - Sep 23
Total with taxes and fees
Riverfront Cabin With Small Beach Short Drive From Nauvoo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Great River Road Hotel Reviews

Fairfield Inn & Suites by Marriott La Crosse Downtown

Fairfield Inn & Suites by Marriott La Crosse Downtown

10/10 Excellent
"The staff was very nice and super helpful. Directed us to great good stops in town."
Melissa 2-night trip
Posted 16 hours ago
Fairfield Inn & Suites by Marriott La Crosse Downtown

Find out more about Great River Road

Everything you need to know about Great River Road vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Great River Road vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Great River Road vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Great River Road vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Great River Road. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Great River Road in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Great River Road rentals

At Expedia, we put the best Great River Road vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Great River Road rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Great River Road vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Great River Road. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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