A historic downtown street with vintage buildings, a church steeple, and a prominent clock tower.

Great River Road Vacation Rentals

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Check prices for these dates

In two weeks
Nov 6 - Nov 8
In two months
Dec 18 - Dec 20
In three months
Jan 15 - Jan 17
In four months
Feb 12 - Feb 14

Our top choices for Great River Road vacation rentals

A bedroom with a large bed, wooden doors, a window with blinds, and a painting on the wall.

1. Cozy Soulard 2BR w/ Free Parking

Cozy Soulard 2BR w/ Free Parking
Soulard
9.6 out of 10, Exceptional, (68 reviews)
"Enjoyed our visit to St. Louis. The host was very accommodating and helpful."
United States
Chad G.
$180 nightly
The price is $194
Oct 25 - Oct 26
Total with taxes and fees
Cozy Soulard 2BR w/ Free Parking
A spacious living area with a gray sofa, a dining table with chairs, a large window with a city view, and a ceiling fan.

2. The Jungle Book | Marcel Stays

The Jungle Book | Marcel Stays
Downtown West
9.2 out of 10, Wonderful, (17 reviews)
"Clean, convenient, comfortable for family travel with pets."
United States
Persis B.
$300 nightly
The price is $303
Oct 25 - Oct 26
Total with taxes and fees
The Jungle Book | Marcel Stays
A dining area with a wooden table, grey upholstered chairs, a bench, a patterned rug, a brick wall, a framed picture, and a potted plant.

3. Centrally located in the Tower Grove East neighborhood!

Centrally located in the Tower Grove East neighborhood!
Tower Grove East
9.8 out of 10, Exceptional, (180 reviews)
"Great place!"
United States
Arthur S.
$152 nightly
The price is $165
Nov 1 - Nov 2
Total with taxes and fees
Centrally located in the Tower Grove East neighborhood!
A modern kitchen with wooden cabinets, a central island, bar stools, and a ceiling fan.

4. 3 King Beds/3Baths Spacious by StayStLouis

3 King Beds/3Baths Spacious by StayStLouis
McKinley Heights
9.8 out of 10, Exceptional, (34 reviews)
"Property is exactly as it is advertised. It was very clean, and stocked with every item you might have forgotten, as a courtesy. The check-in process was clear and smooth. Our host was extremely professional, courteous, and accommodating to all of our needs. Highly recommend this property for your trip to STL!"
United States
Justine
$354 nightly
The price is $386
Oct 26 - Oct 27
Total with taxes and fees
3 King Beds/3Baths Spacious by StayStLouis
A modern living space with a wooden loft, a red chair, a potted plant, and a television on the wall.

5. Urban Cottage Loft near Downtown Free Parking Pet Friendly

Urban Cottage Loft near Downtown Free Parking Pet Friendly
Benton Park West
9.6 out of 10, Exceptional, (84 reviews)
"It was located in a very interesting area (Cherokee Street/Antiques Row) and was near many St. Louis attractions. The loft apartment was was really cozy, small, and nicely decorated. Very unique and creative! In my opinion, it would be ideal for an adult couple; the stairs to the loft bedroom area would be a challenge for some. The kitchen was well equipped with appliances and supplies. The private parking area behind the apartment was just right. The bathroom sink was rather small, but...
United States
Dennis
$140 nightly
The price is $153
Oct 29 - Oct 30
Total with taxes and fees
Urban Cottage Loft near Downtown Free Parking Pet Friendly
A two-story brick building with arched windows and a black door.

6. Brand New! Soulard Charmer - Pet Friendly.

Brand New! Soulard Charmer - Pet Friendly.
Soulard
9.6 out of 10, Exceptional, (58 reviews)
"Great accomodation would come back every time"
Germany
Daniel
$260 nightly
The price is $285
Oct 26 - Oct 27
Total with taxes and fees
Brand New! Soulard Charmer - Pet Friendly.
A living room with a TV, wooden furniture, a fireplace, and a cozy seating area.

7. Charming 2-bedroom, cozy bungalow with sunroom in fabulous St. Louis with WiFi

Charming 2-bedroom, cozy bungalow with sunroom in fabulous St. Louis with WiFi
Bevo Mill
9.0 out of 10, Wonderful, (38 reviews)
"We enjoyed our stay, very quaint house and Julie was an amazing host "
United States
Lori O.
$211 nightly
The price is $230
Oct 22 - Oct 23
Total with taxes and fees
Charming 2-bedroom, cozy bungalow with sunroom in fabulous St. Louis with WiFi
A living room with a wooden entertainment center, a white sofa, and a dining area with a white railing.

8. Spacious, cozy home in Saint Louis

Spacious, cozy home in Saint Louis
St. Louis
10.0 out of 10, Exceptional, (46 reviews)
"Excellent communication and service, very clean, and nice place to stay. We enjoyed our stay!"
United States
Jennifer M.
$290 nightly
The price is $310
Oct 22 - Oct 23
Total with taxes and fees
Spacious, cozy home in Saint Louis
A modern hotel room with a large window, a grey sofa, a wooden coffee table, a bed, and a view of a church spire.

9. Roami at Century Plaza

Roami at Century Plaza
4.0 star property
Downtown Minneapolis
9.4 out of 10, Exceptional, (122 reviews)
"The roof top is amazing make sure to enjoy that."
United States
Mason
$82 nightly
The price is $96
Nov 2 - Nov 3
Total with taxes and fees
Roami at Century Plaza
A bedroom with a bed, a wooden headboard, a window with a view of greenery, and a tray with breakfast items.

10. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
10.0 out of 10, Exceptional, (115 reviews)
"The stay here gets better every time."
United States
cynthia
$159 nightly
The price is $181
Oct 28 - Oct 29
Total with taxes and fees
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
A hotel room with two beds, green walls, and framed pictures of landscapes.

11. Hudson Inn & Suites

Hudson Inn & Suites
3.0 star property
Hudson
8.4 out of 10, Very good, (961 reviews)
"All around it was great"
United States
Dominic M
$81 nightly
The price is $88
Oct 26 - Oct 27
Total with taxes and fees
Hudson Inn & Suites
A modern kitchen with white cabinets, a central island, and a hanging light fixture.

12. California Building

California Building
4.0 star property
New Orleans Central Business District
8.8 out of 10, Excellent, (331 reviews)
"Great room, great price and location."
United States
Phillip
$135 nightly
The price is $156
Nov 9 - Nov 10
Total with taxes and fees
California Building
A rooftop pool area with checkered flooring, lounge chairs, and umbrellas.

13. Memoir Warehouse District

Memoir Warehouse District
4.0 star property
Arts/Warehouse District
9.4 out of 10, Exceptional, (484 reviews)
"Great location"
United States
Vincent
$177 nightly
The price is $209
Nov 2 - Nov 3
Total with taxes and fees
Memoir Warehouse District
A wooden-paneled bedroom with a bed, bedside lamps, a ceiling fan, a toilet, and a small shelf with toiletries.

14. Turn On Inn

Turn On Inn
3.0 star property
Lake Village
9.6 out of 10, Exceptional, (95 reviews)
"Excellent place to stay I stay every time if available"
United States
Christi
$116 nightly
The price is $128
Oct 26 - Oct 27
Total with taxes and fees
Turn On Inn
A modern living room with a glass dining table, grey sofas, and a large TV.

15. The Stallion

The Stallion
4.5 star property
Downtown Memphis
9.8 out of 10, Exceptional, (462 reviews)
"This place was wild and so surprisingly amazing. Clean huge, perfect amenities. We loved the layout, high ceiling everything!"
United States
Doreen
$203 nightly
The price is $242
Nov 4 - Nov 5
Total with taxes and fees
The Stallion
A modern living room with a sofa, a coffee table, and a rug. There is a kitchen in the background, and a bed with a white headboard is visible in the adjacent room.

16. Ironworks

Ironworks
3.5 star property
New Orleans Central Business District
9.6 out of 10, Exceptional, (77 reviews)
"Clean, safe, and great location. Would absolutely stay here again! The Ironworks Coffee is delicious and Ernst Cafe has the best priced beer."
United States
Jessica
$271 nightly
The price is $319
Oct 27 - Oct 28
Total with taxes and fees
Ironworks
A wooden deck with a bench and a staircase leading to a house.

17. Countryside Private Guest Room

Countryside Private Guest Room
Freeburg
10.0 out of 10, Exceptional, (31 reviews)
"Awesome place to stay really nice host would highly recommend!!!!"
United States
Cayson P.
$92 nightly
The price is $98
Oct 22 - Oct 23
Total with taxes and fees
Countryside Private Guest Room
A row of single-family homes with a well-maintained lawn and a tree in the foreground.

18. Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos
3.0 star property
Nauvoo
9.8 out of 10, Exceptional, (459 reviews)
"A great place to stay!"
United States
Renae
$135 nightly
The price is $143
Oct 30 - Oct 31
Total with taxes and fees
Nauvoo Vacation Villas & Condos
A two-story cabin with a balcony, surrounded by autumn foliage and a lake.

19. In the Country a Beautiful 2-bedroom house with its own private lake

In the Country a Beautiful 2-bedroom house with its own private lake
Waterloo
10.0 out of 10, Exceptional, (39 reviews)
"Wonderful place!"
United States
Tina S.
$238 nightly
The price is $252
Oct 22 - Oct 23
Total with taxes and fees
In the Country a Beautiful 2-bedroom house with its own private lake
A modern courtyard with white furniture, a central seating area, and a small lawn.

20. stayAPT Suites Memphis-Cordova-Wolfchase

stayAPT Suites Memphis-Cordova-Wolfchase
4.0 star property
Cordova
8.8 out of 10, Excellent, (109 reviews)
"Nice place easy check in and quiet"
United States
Alfred
$129 nightly
The price is $155
Nov 19 - Nov 20
Total with taxes and fees
stayAPT Suites Memphis-Cordova-Wolfchase
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Great River Road Hotel Reviews

AmericInn by Wyndham Prairie du Chien

AmericInn by Wyndham Prairie du Chien

10/10 Excellent
"We enjoyed our stay!"
Angie 2-night trip
Posted 2 days ago
AmericInn by Wyndham Prairie du Chien

Find out more about Great River Road

Everything you need to know about Great River Road vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Great River Road vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Great River Road vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Great River Road vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Great River Road. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Great River Road in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Great River Road rentals

At Expedia, we put the best Great River Road vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Great River Road rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Great River Road vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Great River Road. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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