Top 10 Hotels in Greencastle, MO (from $62) 2026 - Competitive Prices

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Our top choices for Greencastle hotels

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.

1. Depot Inn and Suites

La Plata

Margaret

$88 nightly

Nov 8 - Nov 9

Total with taxes and fees

A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.

2. Super 8 by Wyndham Kirksville-University Area

Kirksville

Albert

$65 nightly

Nov 22 - Nov 23

Total with taxes and fees

A modern hotel lobby with multiple seating areas, including a bar and dining tables.

3. Hampton Inn Kirksville

Kirksville

Larissa

$114 nightly

Nov 28 - Nov 29

Total with taxes and fees

A buffet with various food items, including omelets and other dishes, arranged in metal serving trays.

4. Holiday Inn Express & Suites Kirksville - University Area by IHG

Kirksville

Kristin

$107 nightly

Nov 29 - Nov 30

Total with taxes and fees

A hotel room with a large bathtub, a bed, a desk, and a television.

5. Baymont by Wyndham Kirksville University Area

Kirksville

James

$64 nightly

Nov 22 - Nov 23

Total with taxes and fees

A modern dining area with a kitchen in the background, a flat-screen TV mounted on the wall, and a comfortable seating arrangement.

6. Quality Inn Kirksville

Kirksville

Don

$75 nightly

Nov 22 - Nov 23

Total with taxes and fees

A wooden deck with tables and chairs overlooking a lake at sunset.

7. Thousand Hills

Kirksville

Michelle

$102 nightly

Nov 19 - Nov 20

Total with taxes and fees

A reception area with a wooden counter, a brick wall, a computer, and a calendar.

8. Budget Host Village Inn

Kirksville

James

$55 nightly

Nov 3 - Nov 4

Total with taxes and fees

A hotel room with two beds, a desk with a chair, a television, a lamp, and a window with blinds.

9. Knights Inn Kirksville

Kirksville

Rhonda

$68 nightly

Nov 3 - Nov 4

Total with taxes and fees

10. Zeke’s Retreat – Hunter’s Getaway with On-Site Taxidermy Shop

Greencastle

Joshua R.

$161 nightly

Nov 30 - Dec 1

Total with taxes and fees

A kitchen with wooden cabinets, a microwave, a sink, and a window with a view.

11. Rescued Wood Bunkhouse-Sleeps 8 hunters. Full kitchen and bath. Lots of parking.

Greencastle

Austin M.

A wooden bridge with a rope railing in a forested area.

12. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Brashear

Shadi H.

A wooden staircase with a railing leading to a dining area with natural light from windows.

13. Second Heaven Lodge Southern Iowa Escape

Moulton

$1,460 nightly

Nov 3 - Nov 4

Total with taxes and fees

A hotel room with a large bed, a sofa, a TV, and a desk.

14. Cozy hotel in charming location with AC comfort

Kirksville

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Where to stay near Greencastle

Outdoor enthusiasts and families will love the charm of Greencastle. Explore scenic parks and enjoy the area's tranquil atmosphere, perfect for relaxation and wellness. Nearby attractions offer opportunities for excursions and quality family time, making it an ideal destination for those seeking both adventure and serenity.

A calm lake with a forested island in the distance.

Kirksville

Discover Kirksville, a welcoming destination perfectly suited for travelers seeking a blend of family-friendly activities, nature, and romance. This charming city offers access to beautiful outdoor spaces like Thousand Hills State Park, while history enthusiasts can explore Truman State University and A.T. Still University. Located about 21 miles by car from Greencastle, Kirksville is a smart choice for a hotel stay, providing a unique experience for those looking to unwind and explore.

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Green City

Enjoy a vibrant getaway in Green City, a fantastic spot for families and nature lovers looking to explore outdoor activities and scenic views. With attractions like Lake Thunderhead for relaxing days by the water, Thousand Hills State Park for hiking and wildlife, and the nearby Truman State University for a touch of history, there's something for everyone. Located about 4 miles from Greencastle, Green City provides an ideal base for your adventures, making it a smart choice for your stay.

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Novinger

If you are a family or nature enthusiast, look no further than Novinger, a charming city known for its scenic beauty and budget-friendly options. Experience the great outdoors at Thousand Hills State Park, enjoy educational opportunities at Truman State University, and relax at local attractions like the nature reserve. With visitor numbers peaking in February, April, and November, you’ll find plenty to explore year-round. Located about 9 miles from Greencastle, Novinger is an ideal choice for your next getaway.

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Milan

Milan stands out as a prime spot for travelers interested in family-friendly experiences and outdoor adventures. With attractions like Lake Thunderhead for scenic relaxation, Gladys Grimes Public Park for family fun, and the historic charm of the Gen. John J. Pershing Boyhood Home State Historic Site, there’s plenty to explore. Located about 14 miles from Greencastle, Milan offers easy access to nature and recreation, making it a smart choice for your next vacation.

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Pollock

Travelers seeking a family-friendly getaway will find Pollock to be the ideal base for their vacation, featuring stunning natural beauty and budget-friendly options. With attractions like Lake Thunderhead and Thousand Hills State Park, outdoor enthusiasts can enjoy a variety of recreational activities, while those interested in city experiences can explore the local urban park and historic sites. Located about 13 miles from Greencastle, Pollock makes for a smart choice for memorable vacations all year round.

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Stay near popular attractions around Greencastle

Greencastle offers a perfect blend of outdoor adventures and scenic beauty, making it an ideal getaway for families and couples alike. Explore historic and modern universities or unwind in nearby national parks, all while soaking in the picturesque surroundings that promise unforgettable experiences.

Truman State University

9.2/10 (152 reviews)

Highly recommended for travelers interested in cultural experiences, Truman State University in Kirksville offers a historic campus rich with vibrant student life and artistic events. Located about 16 miles from Greencastle, it provides an engaging atmosphere perfect for visitors wanting to explore the local academic culture.

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Top Greencastle Hotel Reviews

Super 8 by Wyndham Kirksville-University Area

8/10 Good

"it was a good stay"

New tiny home in an incredible private setting among all nature has to offer.

10/10 Excellent

"Second stay in the last month and half at the Tiny Nest. Again the place was clean and set up awaiting our arrival. They had the place open and ready for us to arrive early and very accommodating to details of our stay. Our family has been staying in the Kirksville area a lot over the last 5 years and this has become our go to place to check first for our stays in the Kirksville area. I highly recommend you try it out, you won’t look elsewhere."

Quaint Guest Cottage

10/10 Excellent

"From the moment you arrive, you are transported in time. This is one of the best cottage experiences I have ever had. I rate it a 10 out of 10 for authentic cottage feel. Owners thought of everything. Would love to have one myself, back in Texas. Owners were gracious to allow us early check-in and late checkout due to our flight. The cottage has easy access to Truman State and ATSU college campuses, we walked and enjoyed our stay in Kirksville so much. That experience all started with the perfect cottage."

Country's Edge Retreat

10/10 Excellent

"We were in town for the Truman State University Family Weekend. We have a large family and the house was large enough for everyone to have their own space. The house was spotless and had everything we needed to make us feel right at home. We were worried that the commute would be bad because it was 10 miles away but it was all one road and seemed to go very fast. We were so happy that we plan on staying here every year."

More cheap stays in Greencastle

Budget Host Village Inn

1304 S Baltimore Kirksville MO

$55 nightly

$62 total

Nov 3 - Nov 4

Total with taxes and fees

Hotels in Greencastle with star-rating

Frequently asked questions

What is the best area to stay in Greencastle?

The best area to stay in Greencastle is near the town center, particularly around the intersection of Main Street and Highway 147, as this is where most of the town's facilities are located.

This central area offers convenience, with local eateries and shops clustered within walking distance. It provides easy access to the few local points of interest, making it a practical base for visitors.

For couples seeking a quiet retreat, staying in this central area provides access to the town's limited amenities while allowing for peaceful evenings.

When is the best time to go to Greencastle?

The best time to go to Greencastle, Missouri, is during the spring and fall months.

Spring, particularly from April to May, offers pleasant weather with blooming landscapes. This is an excellent time for nature enthusiasts and those who enjoy outdoor activities like exploring the nearby conservation areas or taking scenic drives. The temperatures are mild, making it comfortable for sightseeing without the summer heat.

Fall, from September to October, is another ideal period, characterized by cooler temperatures and the vibrant colors of autumn foliage. This season is great for travelers who appreciate picturesque scenery and a relaxed pace.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Greencastle.

How much is the nightly rate at a Greencastle hotel?

Prices for hotels in Greencastle often vary, but you can find a great deal from $62 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Find hotels in Greencastle, MO from $62

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Our top choices for Greencastle hotels

1. Depot Inn and Suites

2. Super 8 by Wyndham Kirksville-University Area

3. Hampton Inn Kirksville

4. Holiday Inn Express & Suites Kirksville - University Area by IHG

5. Baymont by Wyndham Kirksville University Area

6. Quality Inn Kirksville

7. Thousand Hills

8. Budget Host Village Inn

9. Knights Inn Kirksville

10. Zeke’s Retreat – Hunter’s Getaway with On-Site Taxidermy Shop

11. Rescued Wood Bunkhouse-Sleeps 8 hunters. Full kitchen and bath. Lots of parking.

12. Lost Branch Lodge. Complete exterior remodel, spring 2026!

13. Second Heaven Lodge Southern Iowa Escape

14. Cozy hotel in charming location with AC comfort

Where to stay near Greencastle

Kirksville

Green City

Novinger

Milan

Pollock

Stay near popular attractions around Greencastle

Truman State University

Top Greencastle Hotel Reviews

Super 8 by Wyndham Kirksville-University Area

More cheap stays in Greencastle

Budget Host Village Inn

Hotels in Greencastle with star-rating

Frequently asked questions

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