Guadalupe Vacation Rentals

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Our top choices for Guadalupe vacation rentals

3.0 star property
$33 nightly
The price is $36
Dec 28 - Dec 29
Total with taxes and fees
Habitación Privada en Playa Dorada + Kitchenette

Aparthotel in Pajonal

Punta Chame Club and Resort
4.0 star property
9.2 out of 10, Wonderful, (5)
"Endroit bien situé pour rayonner aux alentours. chambres propres et en bon état, il manque juste un peu de luminosité! Très grande piscine très agréable. Personnel disponible et sympathique. juste un peu de bruit le samedi soir car les voisins ont mis la musique fort mais apparemment c'était exceptionnel"
France
Frederic
$179 nightly
The price is $197
Dec 28 - Dec 29
Total with taxes and fees
Punta Chame Club and Resort

Apartment in Amador

La Palma Aparta Suite
3.0 star property
$75 nightly
The price is $82
Dec 29 - Dec 30
Total with taxes and fees
La Palma Aparta Suite
$96 nightly
The price is $96
Dec 27 - Dec 28
Total with taxes and fees
Panama View House – A Hilltop Retreat with Stunning Canal Views
9.0 out of 10, Wonderful, (4)
"Cute and clean place, as described."
United States
Fanny
$107 nightly
The price is $107
Dec 30 - Dec 31
Total with taxes and fees
Top loft with ocean view at La Mimosa de Taboga. A quiet and peaceful home.
3.5 star property
7.4 out of 10, Good, (28)
"Great, clean condo overlooking the pool and ocean. We didn't cook our meals, but used the restaurant on site. Staff was friendly and professional. "
Canada
Timothy
$202 nightly
The price is $222
Dec 28 - Dec 29
Total with taxes and fees
Surfside Beachfront Suites by Playa Caracol Resorts
10.0 out of 10, Exceptional, (1)
"The stay was nice. There is one picture in the listing that shows an air conditioner in the room, but the air conditioner is no longer there. There are fans. The house is only a few blocks from the Panamerican highway. The neighborhood felt safe and it was quiet at night. The interior and exterior were very clean. The kitchen has enough utensils so that we could cook meals. Our car was parked in a gated garage. The hosts were very kind, hospitable, and attentive to our needs. It was perfect for...
United States
Jason S.
$57 nightly
The price is $57
Dec 30 - Dec 31
Total with taxes and fees
Cozy La Chorrera Villa with Private Patio & Nature Views

Apartment in Veracruz

Centriqo by Wynwood house
3.0 star property
$158 nightly
The price is $174
Jan 18 - Jan 19, 2026
Total with taxes and fees
Centriqo by Wynwood house

Vacation Home in Panamá

Oasis with pool near panama canal
9.4 out of 10, Exceptional, (24)
"The place was really comfortable and very close to the city and other tourist attractions and even close to the airport. My family really enjoyed the the pool area and the convenience of the spacious house! Would recommend and I would rent this place on my next vacation."
United States
Wendy F.
$260 nightly
The price is $260
Dec 27 - Dec 28
Total with taxes and fees
Oasis with pool near panama canal

Apartment in Provincia de Panamá Oeste

Great studio beach apartment with wonderful amenities
$136 nightly
The price is $136
Dec 27 - Dec 28
Total with taxes and fees
Great studio beach apartment with wonderful amenities
$85 nightly
The price is $90
Dec 28 - Dec 29
Total with taxes and fees
Cabañas Ecológicas,lo Ideal Para Disfrutar de la Naturaleza, Aire Puro, Animales
$110 nightly
The price is $110
Dec 30 - Dec 31
Total with taxes and fees
Malaya Lodge⎯ Romantic off grid cabin near Panama City
9.4 out of 10, Exceptional, (11)
"We had another wonderful stay at Casa Rosie. It’s the perfect place to unwind."
United States
Dimo
$317 nightly
The price is $317
Dec 28 - Dec 29
Total with taxes and fees
Casa Rosie - relax and unwind in paradise
$227 nightly
The price is $243
Dec 27 - Dec 28
Total with taxes and fees
Villa Ana Eco Lodge w pool | Chicá Altos de Campana.

Vacation Home in panama taboga

Wili taboga's house
$180 nightly
The price is $220
Dec 27 - Dec 28
Total with taxes and fees
Wili taboga's house
$256 nightly
The price is $256
Dec 27 - Dec 28
Total with taxes and fees
Reef Townhouse Tides (T39)
2.0 star property
$135 nightly
The price is $135
Jan 4 - Jan 5, 2026
Total with taxes and fees
Homey and Budget-Friendly Getaway for Families
2.0 star property
$150 nightly
The price is $165
Jan 18 - Jan 19, 2026
Total with taxes and fees
w Splendid 1BR in the Heart of Centriqo

Vacation Home in Provincia de Panamá Oeste

Excellent beach apartment with excellent amenities
$136 nightly
The price is $136
Dec 27 - Dec 28
Total with taxes and fees
Excellent beach apartment with excellent amenities
$140 nightly
The price is $140
Dec 31 - Jan 1, 2026
Total with taxes and fees
Beach apartment in Veracruz, Panama. Beautiful 57mts2 studio apartment.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Guadalupe Hotel Reviews

Find out more about Guadalupe

Everything you need to know about Guadalupe vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Guadalupe vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Guadalupe vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Guadalupe vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Guadalupe. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Guadalupe in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $36 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Guadalupe rentals

At Expedia, we put the best Guadalupe vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Guadalupe rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Guadalupe vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Guadalupe. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Guadalupe?

Yes, we have vacation rentals near popular attractions in Guadalupe, or you can choose a more remote option if you want a relaxing place to stay.

What's the top vacation rental that Guadalupe has to offer?

Oasis with pool near panama canal: This vacation home rental outside of Guadalupe offers an outdoor pool, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind.

What’s there to see and do in Guadalupe?

While you're exploring the area, Altos De Campana National Park and Isla Mandinga are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Campana Viewpoint and Kevin Castle.

What’s a vacation rental in Guadalupe like?

A vacation rental is a private property you can stay in for several days or longer in Guadalupe. Vacation rentals offer extras like WiFi and washers and dryers so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of seclusion away from shared hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a great option for a family getaway.