Guadalupe Vacations from $951

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The Latest Guadalupe vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,440, price is now $951 per person
$951
per person
Jun 17 - Jun 24
found 2 days ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (5,374 reviews)
Hotel was beautiful, the service staff was exceptional and the breakfast selections were fantastic. I would definitely plan to stay at this establishment again when I visit Panamá city again. I would not be opposed to trying one of their other properties based on my experience at the Riu Plaza, Panamá city location.

Reviewed on May 9, 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,654, price is now $1,693 per person
$1,693
per person
Jul 13 - Jul 20
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9.2/10 Wonderful! (1,005 reviews)
Excelente localización personal del hotel muy bueno. La crítica.: hotel no te tiene los útiles básicos como crema para la piel, gorro de baño. Cepillo dental etc. Hay q estar en la recepción para recordar y solicitarlo

Reviewed on May 4, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was $1,758, price is now $1,168 per person
$1,168
per person
Jun 17 - Jun 24
found 2 days ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.4/10 Very Good! (1,524 reviews)
The spa was amazing so relaxing. The breakfast buffet had an assortment of things to eat but it’s better to get there in the am when the food is fresh. Great room with an amazing view! The kid pool was very dirty though I’m talking about bugs and this whitish film. I hope they also have more amenities such as the club and kids area open up. Seems like still recovering from covid. But overall I would stay again.

Reviewed on May 8, 2026

Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,392, price is now $1,666 per person
$1,666
per person
Jun 13 - Jun 20
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.8/10 Exceptional! (27 reviews)
In the middle of the old town, lovely rooftop. Beautiful apartment. Easy check in. WhatsApp line is available if anything was needed or if we had questions.

Reviewed on Mar 12, 2026

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5
Juan Diaz
Price was $1,654, price is now $1,207 per person
$1,207
per person
Jun 17 - Jun 24
found 2 days ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9.6/10 Exceptional! (693 reviews)
This is the definition of a 5 start hotel. We went to celebrate my husbands birthday because he's an avid golfer. It was easy to book tee times and the service was impeccable. The course was wel maintained and even saw a crocodile. The hotel itself went above and beyond because our room wasn't ready at time of arrival.

Reviewed on Apr 5, 2026

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Guadalupe Hotel Deals

Backpackers Las Pesas

Backpackers Las Pesas

2 out of 5
La Chorrera, vía interamericana, Panama City Panama
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Backpackers Las Pesas
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

4.5 out of 5
Amador Avenue & Van Hook Street Panama City Panama
Fully refundable
$74 nightly
The price is $81 total per night from Jun 5 to Jun 6
$81 total
Jun 5 - Jun 6
Total with taxes and fees
8.6/10 Excellent! (1,011 reviews)
Excellent services. Great location

Reviewed on May 8, 2026

Radisson Hotel Panama Canal
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$262 nightly
The price is $262 total per night from Jun 4 to Jun 5
$262 total
Jun 4 - Jun 5
Total with taxes and fees
7.6/10 Good! (1,016 reviews)
My wife and I stayed at Dreams Playa Bonita for a short break. The property is well-maintained and clean. The room had everything we needed. The only slight issue was that the shower water wasn't as hot as we might have wished. The staff at the property was friendly and proactive. After a few days, ...

Reviewed on May 8, 2026

Dreams Playa Bonita Panama - All Inclusive
See all 352 properties in Guadalupe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Guadalupe Vacation Packages

Guadalupe Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Marcos A. Gelabert Intl. Airport (PAC)
Population
6,600

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Frequently asked questions

How much does a Guadalupe vacation package cost?
You can snap up a vacation package to this top destination from $951 on Expedia. However, how much your vacation to Guadalupe costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Guadalupe?
If you'd like to book a cheap Guadalupe vacation package, consider planning a trip in January, July and December. You'll generally find better prices on airfares and hotels during these quieter months — ideal for budget-conscious travelers.
How many days is enough for Guadalupe?
The ideal length of your Guadalupe vacation depends on what you'd like to see and do. Usually, a few days to a week will give you enough time to tick off all the leading sights and discover some hidden treasures along the way.
How to find the best Guadalupe package deals?
Begin your search for a Guadalupe package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the perfect Guadalupe package deal straight away, simply change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Guadalupe adventure underway.
Is it cheaper to book a Guadalupe vacation as a package?
An Expedia vacation package could land you significant savings when compared to arranging stays and flights individually. Better still, you can customize your Guadalupe getaway to fit your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Guadalupe?
Score amazing discounts by booking your flights ahead of time with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for an impromptu Guadalupe getaway.
Does Expedia offer Book Now, Pay Later Guadalupe vacation packages?
Your Guadalupe break should be a relaxing escape from your daily routine, not a reason for money-related stress. So to allow you a bit more flexibility, we've teamed up with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there aren't any late payment fees or hidden costs to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.