Guadalupe Vacations from $738

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The Latest Guadalupe vacation packages

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Price was $1,218, price is now $738 per person
$738
per person
Dec 7 - Dec 11
found 20 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr 18, 2025

Nowhere

Nowhere

3 out of 5
Price was $1,401, price is now $774 per person
$774
per person
Dec 9 - Dec 16
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.2/10 Wonderful! (17 reviews)
What a uniqe location! Get up early, take your time to take in amazing birds and wildlife surrounding you!

Reviewed on Feb 28, 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
Price was $2,668, price is now $1,557 per person
$1,557
per person
Jan 19 - Jan 23
found 10 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
No reviews
Hotel Panamonte

Hotel Panamonte

3.5 out of 5
Price was $1,492, price is now $890 per person
$890
per person
Dec 14 - Dec 19
found 18 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.4/10 Exceptional! (121 reviews)
This is a classic, elegant property that lives up to its reputation. Quality in every regard. On par with some of the finest historic hotels in the country (and I’ve stayed at a few).

Reviewed on Sep 4, 2025

La Coralina Island House

La Coralina Island House

3.5 out of 5
Save 100% on your flight
Price was $2,615, price is now $1,592 per person
$1,592
per person
Dec 9 - Dec 16
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.4/10 Exceptional! (91 reviews)
Everything was great , lovely and peaceful place.

Reviewed on Sep 29, 2025

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Guadalupe Hotel Deals

Backpackers Las Pesas

Backpackers Las Pesas

2 out of 5
La Chorrera, vía interamericana,, Urbanización Loma Brigida, Panama City, Panama
Get rates
Backpackers Las Pesas
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from Nov 8 to Nov 9
$148 total
Nov 8 - Nov 9
Total with taxes and fees
9/10 Wonderful! (1,012 reviews)
Clean room and friendly staff

Reviewed on Nov 4, 2025

Marriott Panama Hotel
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
$272 nightly
The price is $272 total per night from Dec 3 to Dec 4
$272 total
Dec 3 - Dec 4
Total with taxes and fees
7.4/10 Good! (1,002 reviews)
Room was cleaned and stocked everyday

Reviewed on Nov 1, 2025

Dreams Playa Bonita Panama - All Inclusive
See all 218 properties in Guadalupe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Guadalupe Vacation Packages

Guadalupe Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Marcos A. Gelabert Intl. Airport (PAC)
Population
6,600

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Frequently asked questions

How much does a Guadalupe vacation package cost?
You can snap up a vacation package to this top destination from $738 on Expedia. However, how much your vacation to Guadalupe costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Guadalupe?
If you'd like to book a cheap Guadalupe vacation package, consider planning a trip in January, July and December. You'll generally find better prices on airfares and hotels during these quieter months — ideal for budget-conscious travelers.
How many days is enough for Guadalupe?
The ideal length of your Guadalupe vacation depends on what you'd like to see and do. Usually, a few days to a week will give you enough time to tick off all the leading sights and discover some hidden treasures along the way.
How to find the best Guadalupe package deals?
Begin your search for a Guadalupe package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the perfect Guadalupe package deal straight away, simply change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Guadalupe adventure underway.
Is it cheaper to book a Guadalupe vacation as a package?
An Expedia vacation package could land you significant savings when compared to arranging stays and flights individually. Better still, you can customize your Guadalupe getaway to fit your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Guadalupe?
Score amazing discounts by booking your flights ahead of time with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for an impromptu Guadalupe getaway.
Does Expedia offer Book Now, Pay Later Guadalupe vacation packages?
Your Guadalupe break should be a relaxing escape from your daily routine, not a reason for money-related stress. So to allow you a bit more flexibility, we've teamed up with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there aren't any late payment fees or hidden costs to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.