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Vacation Rentals in Panama

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Top Cities in Panama

Our top choices for Panama vacation rentals

3.0 star property
$34 nightly
The price is $37
Dec 14 - Dec 15
Total with taxes and fees
Habitación Privada en Playa Dorada + Kitchenette

Apartment in Bella Vista

Boutique Apartments Panama
3.5 star property
7.6 out of 10, Good, (218)
"The view was amazing and the place was great could stay here again "
United States
Yonnette
$135 nightly
The price is $148
Dec 14 - Dec 15
Total with taxes and fees
Boutique Apartments Panama

Apartment in Calidonia

Studio Apartment with Ocean View
3.0 star property
10.0 out of 10, Exceptional, (1)
"Muy amables en general "
Mexico
Algis
$65 nightly
The price is $72
Jan 2 - Jan 3, 2026
Total with taxes and fees
Studio Apartment with Ocean View

Apartment in David

Peace N' Green
3.0 star property
$43 nightly
The price is $48
Dec 14 - Dec 15
Total with taxes and fees
Peace N' Green
3.0 star property
$160 nightly
The price is $193
Dec 22 - Dec 23
Total with taxes and fees
Living 73 Panamá by Boutique Apartments

Aparthotel in Bocas del Toro

Sun Havens Apartments & Suites
3.0 star property
8.4 out of 10, Very Good, (66)
"Great place and even better people! The room was clean, comfortable and the kitchen was well equipped. The location was great as well as it was only a short walk to everything including the airport. I will definitely stay here again. "
United States
James
$31 nightly
The price is $34
Dec 15 - Dec 16
Total with taxes and fees
Sun Havens Apartments & Suites

Apartment in San Francisco

Boutique Apartments Atlapa
3.0 star property
8.0 out of 10, Very Good, (26)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
$129 nightly
The price is $141
Dec 30 - Dec 31
Total with taxes and fees
Boutique Apartments Atlapa

Villa in Los Naranjos

Casa Mate by Villa Alejandro
3.5 star property
$82 nightly
The price is $90
Dec 14 - Dec 15
Total with taxes and fees
Casa Mate by Villa Alejandro

Aparthotel in Costa del Este

Arcadia Condo Suites
2.5 star property
9.4 out of 10, Exceptional, (160)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
$108 nightly
The price is $119
Dec 15 - Dec 16
Total with taxes and fees
Arcadia Condo Suites

Villa in Boquete

Villa Alejandro
3.5 star property
8.8 out of 10, Excellent, (130)
"Priced right, easy walk to town, safe, quiet & overall great stay! "
United States
John
$69 nightly
The price is $77
Dec 17 - Dec 18
Total with taxes and fees
Villa Alejandro

Condo resort in Alto Boquete

Aires frescos de Boquete
2.0 star property
8.8 out of 10, Excellent, (3)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
$52 nightly
The price is $57
Dec 14 - Dec 15
Total with taxes and fees
Aires frescos de Boquete

Cabin in La Ermita

las cabañas
3.0 star property
$63 nightly
The price is $69
Dec 14 - Dec 15
Total with taxes and fees
las cabañas

Vacation Home in Bocas del Toro

Surfari Bocas
2.5 star property
9.0 out of 10, Wonderful, (52)
"Excelente !!"
United States
Nadia
$26 nightly
The price is $29
Dec 14 - Dec 15
Total with taxes and fees
Surfari Bocas

Apartment in Bocas del Toro

Annies 6th Street Apartment
3.5 star property
$57 nightly
The price is $63
Jan 5 - Jan 6, 2026
Total with taxes and fees
Annies 6th Street Apartment
$214 nightly
The price is $236
Dec 24 - Dec 25
Total with taxes and fees
Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
3.5 star property
7.4 out of 10, Good, (28)
"Great, clean condo overlooking the pool and ocean. We didn't cook our meals, but used the restaurant on site. Staff was friendly and professional. "
Canada
Timothy
$202 nightly
The price is $222
Dec 14 - Dec 15
Total with taxes and fees
Surfside Beachfront Suites by Playa Caracol Resorts
$49 nightly
The price is $54
Dec 20 - Dec 21
Total with taxes and fees
NOE AND Amas Beautiful air Conditioned Villa at El Nazareno

Vacation Home in Panamá

LILIA HOUSE 10 MINUTES AIRPORT
$78 nightly
The price is $78
Dec 17 - Dec 18
Total with taxes and fees
LILIA HOUSE 10 MINUTES AIRPORT

Aparthotel in Bastimentos

Brisas del Mar Bocas
2.0 star property
$89 nightly
The price is $99
Dec 17 - Dec 18
Total with taxes and fees
Brisas del Mar Bocas
2.0 star property
$85 nightly
The price is $94
Dec 14 - Dec 15
Total with taxes and fees
Cabaña Chepo HERRERA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Find out more about Panama

Discover your perfect Panama vacation rental with Expedia

How many vacation rentals are available in Panama?


Expedia has plenty of vacation rentals to choose from in and around  Panama, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Panama?


The selection of Panama vacation rentals we have selected for you start as low as $77 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Panama?


Vacation rentals in Panama come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Panama vacation rentals to suit everyone. 


Why should I choose a vacation rental in Panama?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Panama vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Panama?


Find vacation rentals in Panama by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Panama.  


What amenities are available in a vacation rental in Panama?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Panama vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Panama?   


Everytime is a great time to head to Panama! Staying in a Panama vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Panama. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Panama vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Panama, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Panama vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.  


Explore a world of travel with Expedia