A town with a prominent church, surrounded by hills and mountains.

Guadalupe Vacations from $388

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The Latest Guadalupe Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Sep 21 - Sep 25

    Casa Linda Guatapé + Flight

    Guatapé
    4 nights
    3.0 star property
    7.8/10 - Good (18 reviews)
    "I dont llike to do these, but I got to be honest. Terrible place to stay, terrible acces dangerous. . I dont really recomend it. Take 25 minuts to find it beeing only 50 metters away. If you dont care to damage your vehicle stay away. Im glad the nightmare is over. Tricky photos. Staff it was ok"
    Reviewed July 3, 2026
    Roundtrip San Juan (SJU) - Medellín (MDE)
    SJU - MDENonstop MDE - SJUNonstop
    Save 100% on your flight
    $667
    $388
    per traveler
    found 1 day ago
    Casa Linda Guatapé
  • Oct 8 - Oct 14

    Devú + Flight

    El Poblado
    6 nights
    5.0 star property
    9.8/10 - Exceptional (19 reviews)
    "We really enjoyed our stay at Devu Hotel — it’s a fantastic hotel apartment. The facility is clean, the location is excellent, and the service is superb, meeting all of our expectations. The location couldn’t be more convenient, close to everywhere we needed to go. The apartment itself was clean, well-maintained, and comfortable throughout our stay. What really stood out was the service. The customer service was phenomenal across the board — from the front desk to housekeeping. Most..."
    Reviewed July 13, 2026
    Roundtrip New York (EWR) - Medellín (MDE)
    EWR - MDE1 stop MDE - EWR1 stop
    Save 100% on your flight
    $2,444
    $1,292
    per traveler
    found 1 day ago
    Devú
  • Oct 13 - Oct 17

    Makondo House in Provenza by Nowa + Flight

    El Poblado
    4 nights
    2.0 star property
    Roundtrip San Juan (SJU) - Medellín (MDE)
    SJU - MDENonstop MDE - SJU1 stop
    Save 100% on your flight
    $1,682
    $940
    per traveler
    found 12 hours ago
    Makondo House in Provenza by Nowa
  • Oct 8 - Oct 14

    Autenthico Sajonia Hotel Aeropuerto + Flight

    Rionegro
    6 nights
    2.0 star property
    9.2/10 - Wonderful (84 reviews)
    "Where do I start…if you want to stay at a beautiful place with scenic views where the staff tries to robe you at every turn, then this is the place for you. When we first checked in, the front desk called us from a private number insisting that we pay additional money in cash because we weren’t charged the right amount. After we insisted to talk with the owner they said it was okay and we won’t get overcharged. After we finally were able to accommodate, we tried to look for an uber to get to..."
    Reviewed July 9, 2026
    Roundtrip New York (EWR) - Medellín (MDE)
    EWR - MDE1 stop MDE - EWR1 stop
    Save 100% on your flight
    $1,774
    $996
    per traveler
    found 1 day ago
    Autenthico Sajonia Hotel Aeropuerto
  • Oct 8 - Oct 14

    BoH Collection + Flight

    El Poblado
    6 nights
    3.0 star property
    9.6/10 - Exceptional (5 reviews)
    Roundtrip New York (EWR) - Medellín (MDE)
    EWR - MDE1 stop MDE - EWR1 stop
    Save 100% on your flight
    $2,574
    $1,466
    per traveler
    found 1 day ago
    BoH Collection

Frequently Asked Questions

How much does a Guadalupe vacation package cost?

Offering great value package deals from $388 on Expedia, you'll be thrilled with how little a vacation to Guadalupe costs! Our packages make travel planning easier and your savings go further.

What are the cheapest months to go to Guadalupe?

If you're hoping to snag a cheap Guadalupe vacation package, consider planning a trip in November, December and January. You'll generally find better rates on flights and hotels during these months — ideal for travelers wishing to save money.

How many days is enough for Guadalupe?

The ideal duration of your Guadalupe vacation depends on what you'd like to do and see. Usually, a few days to a week will give you time to go to all the top sights and explore some hidden spots along the way.

How to find the best Guadalupe package deals?

Start your search for a Guadalupe package deal by entering your destination and preferred travel dates under our "Packages" tab. Then add some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the ideal Guadalupe package deal right away, just switch up your dates and search again. Remember that deals are only available for a limited time, so book early and get your Guadalupe getaway off to a flying start.

Is it cheaper to book a Guadalupe vacation as a package?

An Expedia vacation package could land you considerable savings when compared to arranging flights and hotels separately. Better still, you can personalize your Guadalupe trip to match your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.

When to book a vacation package to Guadalupe?

If you've got your Guadalupe travel dates locked in, book as soon as you can to bag some terrific deals. With Expedia, you can generally reserve some flights up to one year in advance. Prefer spur-of-the-moment getaways? Our last-minute deals are perfect for traveling on a whim.

How to plan a trip to Guadalupe?

  1. Choose when to go: Check your schedule and get packing. Your preferred season and the activities available will also help you decide when to escape to Guadalupe.
  2. Work out your budget: Ensure you have enough money to cover everything from food and transportation to activities and flights. Your hotel will probably be the biggest expense during your trip to Guadalupe.
  3. Organize your Guadalupe getaway with our trip planning tool: Look for and book hotels and things to do all in one place. You can also collaborate with family and friends to plan an unforgettable trip to Guadalupe together.
  4. Decide how long to go for: Now that you're up to speed on Guadalupe, you can figure out the perfect length of your vacation. Pull together a rough itinerary and allocate enough time to get through everything on your must-do list.
  5. Combine your accommodations and airfare: Once you've nailed down your trip dates and duration, lock in the ideal Guadalupe vacation package for you.
  6. Book activities and experiences in advance: Whether it's entrance to a major attraction or a walking tour, you won't have to worry about missing out on Guadalupe's best offerings. Find all the incredible things to do in Guadalupe with our dedicated travel guide.

Does Expedia offer Book Now, Pay Later Guadalupe vacation packages?

If you're anything like us, you love traveling the world but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the cost of your Guadalupe trip over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up great vacation packages with payment plans as soon as you spot them.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.